Cytotoxic activity of new neodymium (III) complexes of bis-coumarins

European Journal of Medicinal Chemistry

Volumn 39, Issue 9, 2004, Pages 765-775

  Kostova, Irena ^a   Manolov, Ilia ^a   Momekov, Georgi ^a  

^a Medical University   (China)

Author keywords

Bis coumarins; Cytotoxic activity; IR and NMR spectra; Neodymium (III) complexes

Indexed keywords

3,3' BENZYLIDENEBIS(4 HYDROXY 2H 1 BENZOPYRAN 2 ONE); BENZYLIDENE DERIVATIVE; BIS(4 HYDROXY 2 OXO 2H CHROMEN 3 YL)(1H PYRAZOL 3 YL)METHANE; BIS(4 HYDROXY 2 OXO 2H CHROMEN 3 YL)PYRIDIN 2 YLMETHANE; BIS(4 HYDROXY 2 OXO 2H CHROMEN 3 YL)PYRIDIN 4 YLMETHANE; CARBONYL DERIVATIVE; CHROMENE DERIVATIVE; COUMARIN DERIVATIVE; HYDROXYL GROUP; METAL ION; NEODYMIUM; SODIUM HYDROXIDE; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AQUEOUS SOLUTION; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL LINE; CELL PROLIFERATION; CELL STRAIN HL 60; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IC 50; INFRARED SPECTROMETRY; MALE; MASS SPECTROMETRY; PH; PHYSICAL CHEMISTRY; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; T CELL LEUKEMIA;

ADULT; CELL LINE, TUMOR; CELL SURVIVAL; COUMARINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HL-60 CELLS; HUMANS; LIGANDS; MOLECULAR STRUCTURE; NEODYMIUM; ORGANOMETALLIC COMPOUNDS;

EID: 4444351779     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejmech.2004.06.002     Document Type: Article

References (21)

1. Steffen U.S., Weber B., and Siegers C. Res. Commun. Mol. Pathol. Pharmacol. 99 1998 193-206
2. Egan D., James P., Cooke D., and O'Kennedy R. Cancer Lett. 118 1997 201-211
3. Rosskopt F., Kraus J., and Franz G. Pharmazie 47 1992 139-142
4. Mc Culloch P., and George W.D. Brit. J. Cancer 59 1989 179-183
5. Itokawa H., Yun J.S., Morita H., and Takeya K. Nat. Med. 48 1994 334-335
6. Akman S.A., Doroshow J.H., Dietrich M.F., Chlebowski R.T., and Block J.S. J. Pharmacol. Exp.Ther. 240 1987 486-491
7. Kolodziej H., Kayser O., Woerdenbag H.J., Van Uden W., and Pras N. Z. Naturforsch C. 52 1997 240-244
8. Zhao H., Neamati N., Hong H., Mazumder A., Wang S., Sunder S., Milne G.W.A., Pommier Y., and Burke T.R. J. Med. Chem. 40 1997 242-248
9. Issa Y.M., Omar M.M., Sabrah B.A., and Mohamed S.K. J. Indian Chem. Soc. 69 1992 186-189
10. Bisi C.C., and Carugo O. Inorg. Chim. Acta 159 1989 157-161
11. Jiang D., Deng R., and Wu J. Wuji Huaxue 5 1989 21-28
12. Deng R., Wu J., and Long L. Bull. Soc. Chim. Belg. 101 1992 439-443
13. Kostova I., Manolov I., Nicolova I., Konstantinov S., and Karaivanova M. Eur. J. Med. Chem. 36 2001 339-347
14. Kostova I., Manolov I., Konstantinov S., and Karaivanova M. Eur. J. Med. Chem. 34 1999 63-68
15. Manolov I., Kostova I., Konstantinov S., and Karaivanova M. Eur. J. Med. Chem. 34 1999 853-858
16. Manolov I., Kostova I., Netzeva T., Konstantinov S., and Karaivanova M. Arch. Pharm. Pharm. Med. Chem. 333 2000 93-98
17. Kostova I., Manolov I., Nicolova I., and Danchev N. Il Farmaco 56 2001 707-713
18. Manolov I., Kostova I., and Karaivanova M. Arch. Pharm. Pharm. Med. Chem. 334 2001 157-162
19. Mosmann T. J. Immunol. Methods 65 1983-5563
20. Konstantinov S.M., Eibl H., and Berger M.R. Br. J. of Haematol. 107 1999 365-374
21. Lewis F.D., and Barancyk S.V. J. Am. Chem. Soc. 111 1989 8653-8661