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Chem Comm
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Cytotoxicity, cellular uptake and DNA binding of the novel trinuclear platinum complex BBR 3464 in sensitive- and cisplatin-resistant murine leukemia cells
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Dinuclear platinum complexes form novel intrastrand adducts with d(GpG), an anti-syn conformation of the macrochelate as observed by NMR and molecular modeling
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J Chem Soc Dalton Trans
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Guo Z, Hambley TW, del S. Murdoch P, Sadler PJ: Chelate-ring-opened adducts of [Pt(en)(Me-Mal-O, O′)] (en equals ethane-1,2-diamine, Me-Mal equals 2-methylmalonate) with methionine derivatives: Relevance to the biological activity of platinum anticancer agents. J Chem Soc Dalton Trans 1997:469-478.
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Roat RM, Jerardi MJ, Kopay CB, Heath DC, Clark JA, DeMars JA, Weaver JM, Bezemer E, Reedijk J: Platinum(II) complexes catalyze reactions between platinum(IV) complexes and 9-methylxanthine. J Chem Soc DaltonTrans 1997:3615-3362. This paper shows that Pt(IV) species might be useful as intermediates and prodrugs.
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Dunham SU, Lippard SJ: DNA Sequence context and protein composition modulate HMG-Domain protein recognition of cisplatin-modified DNA. Biochemistry 1997, 36:11428-436. The ultimate action of cell kelling requires at least a protein surrounding the platinated DNA.
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Biochemistry
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Eur J Biochem
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