Transport of multidrug resistance substrates by the Streptococcus agalactiae hemolysin transporter

Journal of Bacteriology

Volumn 188, Issue 16, 2006, Pages 5984-5992

  Gottschalk, Birgit ^a   Bröker, Gerd ^a   Kuhn, Melanie ^a   Aymanns, Simone ^a   Gleich Theurer, Ute ^a   Spellerberg, Barbara ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; DAUNORUBICIN; DOXORUBICIN; HEMOLYSIN; MULTIDRUG RESISTANCE PROTEIN; RHODAMINE 6G; VIRULENCE FACTOR; ANTIINFECTIVE AGENT; CARRIER PROTEIN; RESERPINE;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL MENINGITIS; BACTERIAL PNEUMONIA; BACTERIAL STRAIN; CONTROLLED STUDY; COW; CYL GENE; CYLA GENE; CYLB GENE; CYLK GENE; DELETION MUTANT; GENE CLUSTER; GENE MUTATION; HEMOLYSIS; NEWBORN SEPSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN TRANSPORT; STREPTOCOCCUS AGALACTIAE; UDDER; WILD TYPE; BACTERIOLYSIS; ESCHERICHIA COLI; GENE DELETION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MULTIDRUG RESISTANCE; NUCLEOTIDE SEQUENCE; TIME;

BOS TAURUS; STREPTOCOCCUS AGALACTIAE; STREPTOCOCCUS SP. 'GROUP B';

ANTI-BACTERIAL AGENTS; BACTERIOLYSIS; BASE SEQUENCE; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; GENE DELETION; HEMOLYSIN PROTEINS; MEMBRANE TRANSPORT PROTEINS; RESERPINE; STREPTOCOCCUS AGALACTIAE; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 33748644399     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.00768-05     Document Type: Article

References (32)

1. Ahmed, M., C. M. Borsch, A. A. Neyfakh, and S. Schuldiner. 1993. Mutants of the Bacillus subtilis multidrug transporter Bmr with altered sensitivity to the antihypertensive alkaloid reserpine. J. Biol. Chem. 268:11086-11089.
2. Biswas, I., A. Gruss, D. Ehrlich, and E. Maguin. 1993. High-efficiency gene inactivation and replacement system for gram-positive bacteria. J. Bacteriol. 175:3628-3635.
3. Bolhuis, H., D. Molenaar, G. Poelarends, H. W. van Veen, B. Poolman, A. J. Driessen, and W. N. Konings. 1994. Proton motive force-driven and ATP-dependent drug extrusion systems in multidrug-resistant Lactococcus lactis. J. Bacteriol. 176:6957-6964.
4. Dal, M. C., and H. Monteil. 1983. Hemolysin produced by group B Streptococcus agalactiae. FEMS Microbiol. Lett. 16:89-94.
5. Davis, D. R., J. B. McAlpine, C. J. Pazoles, M. K. Talbot, E. A. Alder, C. White, B. M. Jonas, B. E. Murray, G. M. Weinstock, and B. L. Rogers. 2001. Enterococcus faecalis multi-drug resistance transporters: application for antibiotic discovery. J. Mol. Microbiol. Biotechnol. 3:179-184.
6. De la Rosa, M., R. Villareal, D. Vega, C. Miranda, and A. Martinzbrocal. 1983. Granada medium for the detection and identification of group B streptococci. J. Clin. Microbiol. 18:779-785.
7. Doran, K. S., J. C. Chang, V. M. Benoit, L. Eckmann, and V. Nizet. 2002. Group B streptococcal beta-hemolysin/cytolysin promotes invasion of human lung epithelial cells and the release of interleukin-8. J. Infect. Dis. 185:196-203.
8. Doran, K. S., G. Y. Liu, and V. Nizet. 2003. Group B streptococcal beta-hemolysin/cytolysin activates neutrophil signaling pathways in brain endothelium and contributes to development of meningitis. J. Clin. Investig. 112:736-744.
9. Farley, M. 1995. Group B streptococcal infection in older patients. Spectrum of disease and management strategies. Drugs Aging 6:293-300.
10. Franken, C., G. Haase, C. Brandt, J. Weber-Heynemann, S. Martin, C. Lammler, A. Podbielski, R. Lutticken, and B. Spellerberg. 2001. Horizontal gene transfer and host specificity of beta-haemolytic streptococci: the role of a putative composite transposon containing scpB and lmb. Mol. Microbiol. 41:925-935.
11. Guilfoile, P. G., and C. R. Hutchinson. 1991. A bacterial analog of the mdr gene of mammalian tumor cells is present in Streptomyces peucetius, the producer of daunorubicin and doxorubicin. Proc. Natl. Acad. Sci. USA 88:8553-8557.
12. Holland, B., S. Cole, K. Kuchler, and C. Higgins. 2003. ABC proteins from bacteria to man. Academic Press, San Diego, Calif.
13. Karow, M., and C. Georgopoulos. 1993. The essential Escherichia coli msbA gene, a multicopy suppressor of null mutations in the htrB gene, is related to the universally conserved family of ATP-dependcnt translocators. Mol. Microbiol. 7:69-79.
14. Kling, D. E., L. C. Madoff, and J. L. Michel. 1999. Subcellular fractionation of group B Streptococcus. BioTechniques 27:24-6:28.
15. Luck, S., M. Torny, K. d'Agapeyeff, A. Pitt, P. Heath, A. Breathnach, and A. B. Russell. 2003. Estimated early-onset group B streptococcal neonatal disease. Lancet 361:1953-1954.
16. Mackman, N., and I. B. Holland. 1984. Functional characterization of a cloned haemolysin determinant from E. coli of human origin, encoding information for the secretion of a 107K polypeptide. Mol. Gen. Genet. 196:129-134.
17. Marchlewicz, B. A., and J. L. Duncan. 1980. Properties of a hemolysin produced by group B streptococci. Infect. Immun. 30:805-813.
18. Neyfakh, A. A., C. M. Borsch, and G. W. Kaatz. 1993. Fluoroquinolone resistance protein NorA of Staphylococcus aureus is a multidrug efflux transporter. Antimicrob. Agents Chemother. 37:128-129.
19. Nishino, K., and A. Yamaguchi. 2001. Overexpression of the response regulator evgA of the two-component signal transduction system modulates multidrug resistance conferred by multidrug resistance transporters. J. Bacteriol. 183:1455-1458.
20. Pospiech, A., and B. Neumann. 1995. A versatile quick-prep of genomic DNA from gram-positive bacteria. Trends Genet. 11:217-218.
21. Pritzlaff, C. A., J. C. Chang, S. P. Kuo, G. S. Tamura, C. E. Rubens, and V. Nizet. 2001. Genetic basis for the beta-haemolytic/cytolytic activity of group B Streptococcus. Mol. Microbiol. 39:236-247.
22. Putman, M., H. W. van Veen, and W. N. Konings. 2000. Molecular properties of bacterial multidrug transporters. Microbiol. Mol. Biol. Rev. 64:672-693.
23. Reuter, G., T. Janvilisri, H. Venter, S. Shahi, L. Balakrishnan, and H. W. van Veen. 2003. The ATP binding cassette multidrug transporter LmrA and lipid transporter MsbA have overlapping substrate specificities. J. Biol. Chem. 278:35193-35198.
24. Ricci, M. L., R. Manganelli, C. Berneri, G. Orefici, and G. Pozzi. 1994. Electrotransformation of Streptococcus agalactiae with plasmid DNA. FEMS Microbiol. Lett. 119:47-52.
25. Sakamoto, K., A. Margolles, H. W. van Veen, and W. N. Konings. 2001. Hop resistance in the beer spoilage bacterium Lactobacillus brevis is mediated by the ATP-binding cassette multidrug transporter HorA. J. Bacteriol. 183:5371-5375.
26. Spellerberg, B., S. Martin, C. Brandt, and R. Lutticken. 2000. The cyl genes of Streptococcus agalactiae are involved in the production of pigment. FEMS Microbiol. Lett. 188:125-128.
27. Spellerberg, B., S. Martin, C. Franken, R. Berner, and R. Lutticken. 2000. Identification of a novel insertion sequence element in Streptococcus agalactiae. Gene 241:51-56.
28. Spellerberg, B., B. Pohl, G. Haase, S. Martin, J. Weber-Heynemann, and R. Lütticken. 1999. Identification of genetic determinants for the hemolytic activity of Streptococcus agalactiae by ISS1 transposition. J. Bacteriol. 181:3212-3219.
29. Tatusov, R. L., R. V. Koonin, and D. J. Lipman. 1997. A genomic perspective on protein families. Science 278:631-637.
30. Trieu-Cuot, P., C. Carlier, C. Poyart-Salmeron, and P. Courvalin. 1990. A pair of mobilizable shuttle vectors conferring resistance to spectinomycin for molecular cloning in Escherichia coli and in gram-positive bacteria. Nucleic Acids Res. 18:4296.
31. van Veen, H. W., A. Margolles, M. Muller, C. F. Higgins, and W. N. Konings. 2000. The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism. EMBO J. 19:2503-2514.
32. Zangwill, K., A. Schuchat, and J. D. Wenger. 1992. Group B streptococcal disease in the United States, 1990: report from a multistate active surveillance system. Morb. Mortal. Wkly. Rep. CDC Surveill. Summ. 41:25-32.