-
1
-
-
0025304678
-
Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells
-
Borchelt, D. R., M. Scott, A. Taraboulos, N. Stahl, and S. B. Prusiner. 1990. Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells. J. Cell Biol. 110:743-752.
-
(1990)
J. Cell Biol.
, vol.110
, pp. 743-752
-
-
Borchelt, D.R.1
Scott, M.2
Taraboulos, A.3
Stahl, N.4
Prusiner, S.B.5
-
2
-
-
0026775909
-
Evidence for synthesis of scrapie prion proteins in the endocytic pathway
-
Borchelt, D. R., A. Taraboulos, and S. B. Prusiner. 1992. Evidence for synthesis of scrapie prion proteins in the endocytic pathway. J. Biol. Chem. 267:16188-16199.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 16188-16199
-
-
Borchelt, D.R.1
Taraboulos, A.2
Prusiner, S.B.3
-
3
-
-
0141515178
-
TSE strain variation
-
Bruce, M. E. 2003. TSE strain variation. Br. Med. Bull. 66:99-108.
-
(2003)
Br. Med. Bull.
, vol.66
, pp. 99-108
-
-
Bruce, M.E.1
-
4
-
-
0026099887
-
The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: Implications for the nature of the agent and host control of pathogenesis
-
Bruce, M. E., I. McConnell, H. Fraser, and A. G. Dickinson. 1991. The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis. J. Gen. Virol. 72:595-603.
-
(1991)
J. Gen. Virol.
, vol.72
, pp. 595-603
-
-
Bruce, M.E.1
McConnell, I.2
Fraser, H.3
Dickinson, A.G.4
-
5
-
-
0023928927
-
Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins
-
Butler, D. A., M. R. Scott, J. M. Bockman, D. R. Borchelt, A. Taraboulos, K. K. Hsiao, D. T. Kingsbury, and S. B. Prusiner. 1988. Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins. J. Virol. 62:1558-1564.
-
(1988)
J. Virol.
, vol.62
, pp. 1558-1564
-
-
Butler, D.A.1
Scott, M.R.2
Bockman, J.M.3
Borchelt, D.R.4
Taraboulos, A.5
Hsiao, K.K.6
Kingsbury, D.T.7
Prusiner, S.B.8
-
6
-
-
0025991466
-
The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive
-
Caughey, B., and G. J. Raymond. 1991. The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive. J. Biol. Chem. 266:18217-18223.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 18217-18223
-
-
Caughey, B.1
Raymond, G.J.2
-
7
-
-
0025944507
-
Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy
-
Caughey, B. W., A. Dong, K. S. Bhat, D. Ernst, S. F. Hayes, and W. S. Caughey. 1991. Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy. Biochemistry 30:7672-7680.
-
(1991)
Biochemistry
, vol.30
, pp. 7672-7680
-
-
Caughey, B.W.1
Dong, A.2
Bhat, K.S.3
Ernst, D.4
Hayes, S.F.5
Caughey, W.S.6
-
8
-
-
7444240183
-
Probing the instabilities in the dynamics of helical fragments from mouse PrPC
-
Dima, R. I., and D. Thirumalai. 2004. Probing the instabilities in the dynamics of helical fragments from mouse PrPC. Proc. Natl. Acad. Sci. USA 101:15335-15340.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 15335-15340
-
-
Dima, R.I.1
Thirumalai, D.2
-
9
-
-
0035979274
-
Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody
-
Enari, M., E. Flechsig, and C. Weissmann. 2001. Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody. Proc. Natl. Acad. Sci. USA 98:9295-9299.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9295-9299
-
-
Enari, M.1
Flechsig, E.2
Weissmann, C.3
-
10
-
-
0031183651
-
Three-dimensional NMR structure of a self-folding domain of the prion protein PrP(121-231)
-
Glockshuber, R., S. Hornemann, R. Riek, G. Wider, M. Billeter, and K. Wuthrich. 1997. Three-dimensional NMR structure of a self-folding domain of the prion protein PrP(121-231). Trends Biochem. Sci. 22:241-242.
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 241-242
-
-
Glockshuber, R.1
Hornemann, S.2
Riek, R.3
Wider, G.4
Billeter, M.5
Wuthrich, K.6
-
11
-
-
2942616602
-
Evidence for assembly of prions with left-handed beta-helices into trimers
-
Govaerts, C., H. Wille, S. B. Prusiner, and F. E. Cohen. 2004. Evidence for assembly of prions with left-handed beta-helices into trimers. Proc. Natl. Acad. Sci. USA 101:8342-8347.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8342-8347
-
-
Govaerts, C.1
Wille, H.2
Prusiner, S.B.3
Cohen, F.E.4
-
12
-
-
0031473847
-
SWISS-MODEL and the Swiss-Pdb-Viewer: An environment for comparative protein modeling
-
Guex, N., and M. C. Peitsch. 1997. SWISS-MODEL and the Swiss-Pdb-Viewer: an environment for comparative protein modeling. Electrophoresis 18:2714-2723.
-
(1997)
Electrophoresis
, vol.18
, pp. 2714-2723
-
-
Guex, N.1
Peitsch, M.C.2
-
13
-
-
0035812752
-
Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies
-
Heppner, F. L., C. Musahl, I. Arrighi, M. A. Klein, T. Rulicke, B. Oesch, R. M. Zinkernagel, U. Kalinke, and A. Aguzzi. 2001. Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies. Science 294:178-182.
-
(2001)
Science
, vol.294
, pp. 178-182
-
-
Heppner, F.L.1
Musahl, C.2
Arrighi, I.3
Klein, M.A.4
Rulicke, T.5
Oesch, B.6
Zinkernagel, R.M.7
Kalinke, U.8
Aguzzi, A.9
-
14
-
-
0030878056
-
Recombinant full-length murine prion protein, mPrP(23-231): Purification and spectroscopic characterization
-
Hornemann, S., C. Korth, B. Oesch, R. Riek, G. Wider, K. Wuthrich, and R. Glockshuber. 1997. Recombinant full-length murine prion protein, mPrP(23-231): purification and spectroscopic characterization. FEBS Lett. 413:277-281.
-
(1997)
FEBS Lett.
, vol.413
, pp. 277-281
-
-
Hornemann, S.1
Korth, C.2
Oesch, B.3
Riek, R.4
Wider, G.5
Wuthrich, K.6
Glockshuber, R.7
-
15
-
-
12144271772
-
NMR structure of the bovine prion protein isolated from healthy calf brains
-
Hornemann, S., C. Schorn, and K. Wuthrich. 2004. NMR structure of the bovine prion protein isolated from healthy calf brains. EMBO Rep. 5:1159-1164.
-
(2004)
EMBO Rep.
, vol.5
, pp. 1159-1164
-
-
Hornemann, S.1
Schorn, C.2
Wuthrich, K.3
-
16
-
-
0035834680
-
Mutant prion proteins are partially retained in the endoplasmic reticulum
-
Ivanova, L., S. Barmada, T. Kummer, and D. A. Harris. 2001. Mutant prion proteins are partially retained in the endoplasmic reticulum. J. Biol. Chem. 276:42409-42421.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42409-42421
-
-
Ivanova, L.1
Barmada, S.2
Kummer, T.3
Harris, D.A.4
-
17
-
-
0030967895
-
Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform
-
James, T. L., H. Liu, N. B. Ulyanov, S. Farr-Jones, H. Zhang, D. G. Donne, K. Kaneko, D. Groth, I. Mehlhorn, S. B. Prusiner, and F. E. Cohen. 1997. Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform. Proc. Natl. Acad. Sci. USA 94:10086-10091.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10086-10091
-
-
James, T.L.1
Liu, H.2
Ulyanov, N.B.3
Farr-Jones, S.4
Zhang, H.5
Donne, D.G.6
Kaneko, K.7
Groth, D.8
Mehlhorn, I.9
Prusiner, S.B.10
Cohen, F.E.11
-
18
-
-
0037048655
-
Most of the structural elements of the globular domain of murine prion protein form fibrils with predominant beta-sheet structure
-
Jamin, N., Y. M. Coic, C. Landon, L. Ovtracht, F. Baleux, J. M. Neumann, and A. Sanson. 2002. Most of the structural elements of the globular domain of murine prion protein form fibrils with predominant beta-sheet structure. FEBS Lett. 529:256-260.
-
(2002)
FEBS Lett.
, vol.529
, pp. 256-260
-
-
Jamin, N.1
Coic, Y.M.2
Landon, C.3
Ovtracht, L.4
Baleux, F.5
Neumann, J.M.6
Sanson, A.7
-
20
-
-
0033613203
-
Evidence for the role of PrP(C) helix 1 in the hydrophilic seeding of prion aggregates
-
Morrissey, M. P., and E. I. Shakhnovich. 1999. Evidence for the role of PrP(C) helix 1 in the hydrophilic seeding of prion aggregates. Proc. Natl. Acad. Sci. USA 96:11293-11298.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 11293-11298
-
-
Morrissey, M.P.1
Shakhnovich, E.I.2
-
21
-
-
0027332116
-
Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins
-
Pan, K. M., M. Baldwin, J. Nguyen, M. Gasset, A. Serban, D. Groth, I. Mehlhorn, Z. Huang, R. J. Fletterick, F. E. Cohen, et al. 1993. Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins. Proc. Natl. Acad. Sci. USA 90:10962-10966.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10962-10966
-
-
Pan, K.M.1
Baldwin, M.2
Nguyen, J.3
Gasset, M.4
Serban, A.5
Groth, D.6
Mehlhorn, I.7
Huang, Z.8
Fletterick, R.J.9
Cohen, F.E.10
-
23
-
-
0029937271
-
NMR structure of the mouse prion protein domain PrP(121-321)
-
Riek, R., S. Hornemann, G. Wider, M. Billeter, R. Glockshuber, and K. Wuthrich. 1996. NMR structure of the mouse prion protein domain PrP(121-321). Nature 382:180-182.
-
(1996)
Nature
, vol.382
, pp. 180-182
-
-
Riek, R.1
Hornemann, S.2
Wider, G.3
Billeter, M.4
Glockshuber, R.5
Wuthrich, K.6
-
24
-
-
0030836511
-
NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231)
-
Riek, R., S. Hornemann, G. Wider, R. Glockshuber, and K. Wuthrich. 1997. NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231). FEBS Lett. 413:282-288.
-
(1997)
FEBS Lett.
, vol.413
, pp. 282-288
-
-
Riek, R.1
Hornemann, S.2
Wider, G.3
Glockshuber, R.4
Wuthrich, K.5
-
25
-
-
0027182522
-
Conformational transitions, dissociation, and unfolding of scrapie amyloid (prion) protein
-
Safar, J., P. P. Roller, D. C. Gajdusek, and C. J. Gibbs, Jr. 1993. Conformational transitions, dissociation, and unfolding of scrapie amyloid (prion) protein. J. Biol. Chem. 268:20276-20284.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 20276-20284
-
-
Safar, J.1
Roller, P.P.2
Gajdusek, D.C.3
Gibbs Jr., C.J.4
-
26
-
-
0031720905
-
Eight prion strains have PrP(Sc) molecules with different conformations
-
Safar, J., H. Wille, V. Itri, D. Groth, H. Serban, M. Torchia, F. E. Cohen, and S. B. Prusiner. 1998. Eight prion strains have PrP(Sc) molecules with different conformations. Nat. Med. 4:1157-1165.
-
(1998)
Nat. Med.
, vol.4
, pp. 1157-1165
-
-
Safar, J.1
Wille, H.2
Itri, V.3
Groth, D.4
Serban, H.5
Torchia, M.6
Cohen, F.E.7
Prusiner, S.B.8
-
27
-
-
0027086835
-
Chimeric prion protein expression in cultured cells and transgenic mice
-
Scott, M. R., R. Kohler, D. Foster, and S. B. Prusiner. 1992. Chimeric prion protein expression in cultured cells and transgenic mice. Protein Sci. 1:986-997.
-
(1992)
Protein Sci.
, vol.1
, pp. 986-997
-
-
Scott, M.R.1
Kohler, R.2
Foster, D.3
Prusiner, S.B.4
-
28
-
-
0038576230
-
The role of helix 1 aspartates and salt bridges in the stability and conversion of prion protein
-
Speare, J. O., T. S. Rush III, M. E. Bloom, and B. Caughey. 2003. The role of helix 1 aspartates and salt bridges in the stability and conversion of prion protein. J. Biol. Chem. 278:12522-12529.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 12522-12529
-
-
Speare, J.O.1
Rush III, T.S.2
Bloom, M.E.3
Caughey, B.4
-
29
-
-
0034789531
-
Deletion of β-strand and α-helix secondary structure in normal prion protein inhibits formation of its protease-resistant isoform
-
Vorberg, I., K. Chan, and S. A. Priola. 2001. Deletion of β-strand and α-helix secondary structure in normal prion protein inhibits formation of its protease-resistant isoform. J. Virol. 75:10024-10032.
-
(2001)
J. Virol.
, vol.75
, pp. 10024-10032
-
-
Vorberg, I.1
Chan, K.2
Priola, S.A.3
-
30
-
-
0141849458
-
Molecular and clinical classification of human prion disease
-
Wadsworth, J. D., A. F. Hill, J. A. Beck, and J. Collinge. 2003. Molecular and clinical classification of human prion disease. Br. Med. Bull. 66:241-254.
-
(2003)
Br. Med. Bull.
, vol.66
, pp. 241-254
-
-
Wadsworth, J.D.1
Hill, A.F.2
Beck, J.A.3
Collinge, J.4
-
31
-
-
0037133587
-
Structural studies of the scrapie prion protein by electron crystallography
-
Wille, H., M. D. Michelitsch, V. Guenebaut, S. Supattapone, A. Serban, F. E. Cohen, D. A. Agard, and S. B. Prusiner. 2002. Structural studies of the scrapie prion protein by electron crystallography. Proc. Natl. Acad. Sci. USA 99:3563-3568.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 3563-3568
-
-
Wille, H.1
Michelitsch, M.D.2
Guenebaut, V.3
Supattapone, S.4
Serban, A.5
Cohen, F.E.6
Agard, D.A.7
Prusiner, S.B.8
-
32
-
-
0037665405
-
Determinants of the in vivo folding of the prion protein. A bipartite function of helix 1 in folding and aggregation
-
Winklhofer, K. F., J. Heske, U. Heller, A. Reintjes, W. Muranyi, I. Moarefi, and J. Tatzelt. 2003. Determinants of the in vivo folding of the prion protein. A bipartite function of helix 1 in folding and aggregation. J. Biol. Chem. 278:14961-14970.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 14961-14970
-
-
Winklhofer, K.F.1
Heske, J.2
Heller, U.3
Reintjes, A.4
Muranyi, W.5
Moarefi, I.6
Tatzelt, J.7
-
33
-
-
0034758223
-
Conformational change, aggregation and fibril formation induced by detergent treatments of cellular prion protein
-
Xiong, L. W., L. D. Raymond, S. F. Hayes, G. J. Raymond, and B. Caughey. 2001. Conformational change, aggregation and fibril formation induced by detergent treatments of cellular prion protein. J. Neurochem. 79:669-678.
-
(2001)
J. Neurochem.
, vol.79
, pp. 669-678
-
-
Xiong, L.W.1
Raymond, L.D.2
Hayes, S.F.3
Raymond, G.J.4
Caughey, B.5
-
34
-
-
2542434845
-
Calpain-dependent endoproteolytic cleavage of PrPSc modulates scrapie prion propagation
-
Yadavalli, R., R. P. Guttmann, T. Seward, A. P. Centers, R. A. Williamson, and G. C. Telling. 2004. Calpain-dependent endoproteolytic cleavage of PrPSc modulates scrapie prion propagation. J. Biol. Chem. 279:21948-21956.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 21948-21956
-
-
Yadavalli, R.1
Guttmann, R.P.2
Seward, T.3
Centers, A.P.4
Williamson, R.A.5
Telling, G.C.6
-
35
-
-
0346749511
-
CD and NMR studies of prion protein (PrP) helix 1. Novel implications for its role in the PrPC→PrPSc conversion process
-
Ziegler, J., H. Sticht, U. C. Marx, W. Muller, P. Rosch, and S. Schwarzinger. 2003. CD and NMR studies of prion protein (PrP) helix 1. Novel implications for its role in the PrPC→PrPSc conversion process. J. Biol. Chem. 278:50175-50181.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 50175-50181
-
-
Ziegler, J.1
Sticht, H.2
Marx, U.C.3
Muller, W.4
Rosch, P.5
Schwarzinger, S.6
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