Expression of Helicobacter pylori urease subunit B gene in transgenic rice

Biotechnology Letters

Volumn 28, Issue 20, 2006, Pages 1661-1666

  Gu, Qing ^a,b   Han, Ning ^a   Liu, Jianyi ^c   Zhu, Muyuan ^a  

^a ZHEJIANG GONGSHANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c NINGBO MUNICIPAL CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

Author keywords

Helicobacter pylori; Transgenic rice; ureB; Vaccine

Indexed keywords

ANTISERUM; HELICOBACTER PYLORI; TRANSGENIC RICE; UREB;

BACTERIA; ENZYMES; GENES; VACCINES;

PLANTS (BOTANY);

BACTERIAL PROTEIN; BACTERIAL VACCINE; EDIBLE VACCINE; HYBRID PROTEIN; PROTEIN SUBUNIT; UREASE;

ARTICLE; BIOSYNTHESIS; ENZYMOLOGY; GENETICS; HELICOBACTER PYLORI; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; PROMOTER REGION; RHIZOBIUM; RICE; TRANSGENIC PLANT;

BACTERIAL PROTEINS; BACTERIAL VACCINES; HELICOBACTER PYLORI; HUMANS; ORYZA SATIVA; PLANTS, GENETICALLY MODIFIED; PROMOTER REGIONS (GENETICS); PROMOTER REGIONS, GENETIC; PROTEIN SUBUNITS; RECOMBINANT FUSION PROTEINS; RHIZOBIUM; UREASE; VACCINES, EDIBLE;

AGROBACTERIUM; HELICOBACTER PYLORI; RHIZOBIUM;

EID: 33748555860     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-006-9141-4     Document Type: Article

References (17)

1. Arakawa T, Chong DK, Langridge WH (1998) Efficacy of a food plant-based oral cholera toxin B subunit vaccine. Nature Biotechnol 16:292-297
2. Bazzoli F, Pozzato P, Rokkas T (2002) Helicobacter pylori: the challenge in therapy. Helicobacter 7:43-49
3. Del Giudice G, Covacci A, Telford JL, Montecucco C, Rappuoli R (2001) The design of vaccines against Helicobacter pylori and their development. Annu Rev Immunol 19:523-563
4. Domansky N, Ehsani P, Salmanian AH, Medvedeva T (1995) Organ-specific expression of hepatitis B surface antigen in potato. Biotechnol Lett 17:863-866
5. Ermak TH, Giannasca PJ, Nichols R, Myers GA, Nedrud J, Weltzin R, Lee CK, Kleanthous H, Monath TP (1998) Immunization of mice with urease vaccine affords protection against Helicobacter pylori infection in the absence of antibodies and is mediated by MHC class II-restricted responses. J Exp Med 188:2277-2288
6. Ferrero RL, Thiberge JM, Huerre M, Labigne A (1994) Recombinant antigens prepared from the urease subunits of Helicobacter spp.: evidence of protection in a mouse model of gastric infection. Infect Immun 62:4981-4989
7. Gomez N, Wigdorovitz A, Castanon S, Gil F, Ordas R, Borca MV, Escribano JM (2000) Oral immunogenicity of the plant derived spike protein from swine-transmissible gastroenteritis coronavirus. Arch Virol 145:1725-1732
8. Haq TA, Mason HS, Clements JD, Arntzen CJ (1995) Oral immunization with a recombinant bacterial antigen produced in transgenic plants. Science 268:714-716
9. Hiei Y, Komari T, Kubo T (1997) Transformation of rice mediated by Agrobacterium tumefaciens. Plant Mol Biol 35:205-218
10. Holsters M, de Waele D, Depicker A, Messens E, van Montagu M, Schell J (1978) Transfection and transformation of Agrobacterium tumefaciens. Mol Gen Genet 163:181-187
11. Jefferson RA, Kavanagh TA, Bevan MW (1987) GUS fusions: beta-glucuronidase as a sensitive and versatile gene fusion marker in higher plants. EMBO J 6:3901-3907
12. Mason HS, Ball JM, Shi JJ, Jiang X, Estes MK, Arntzen CJ (1996) Expression of Norwalk virus capsid protein in transgenic tobacco and potato and its oral immunogenicity in mice. Proc Natl Acad Sci USA 93:5335-5340
13. Richter LJ, Thanavala Y, Arntzen CJ, Mason HS (2000) Production of hepatitis B surface antigen in transgenic plants for oral immunization. Nature Biotechnol 18:1167-1171
14. Sheikh NA, al-Shamisi M, Morrow WJ (2000) Delivery systems for molecular vaccination. Curr Opin Mol Ther 2:37-54
15. Tacket CO, Mason HS, Losonsky G, Clements JD, Levine MM, Arntzen CJ (1998) Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato. Nature Med 4:607-609
16. Telford JL, Ghiara P (1996) Prospects for the development of a vaccine against Helicobacter pylori. Drugs 52:799-804
17. Wang H, Qi M, Cutler AJ (1993) A simple method of preparing plant samples for PCR. Nucleic Acids Res 21:4153-4154