3-Demethoxy-3-glycosylaminothiocolchicines: Synthesis of a new class of putative muscle relaxant compounds

Journal of Medicinal Chemistry

Volumn 49, Issue 18, 2006, Pages 5571-5577

  Gelmi, Maria Luisa ^a   Pocar, Donato ^a   Pontremoli, Guido ^a   Pellegrino, Sara ^a   Bombardelli, Ezio ^b   Fontana, Gabriele ^b   Riva, Antonella ^b   Balduini, Walter ^c   Carloni, Silvia ^c   Cimino, Mauro ^c   Johnson, Francis ^d  

^a UNIVERSITY OF MILAN   (Italy)

^b INDENA S P A   (Italy)

^c UNIVERSITY OF URBINO   (Italy)

^d STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINO 3 DEMETHOXYTHIOCOLCHICINE; 3 DEMETHOXY 3 GLYCOSYLAMINOTHIOCOLCHICINE DERIVATIVE; 3 O NORTHIOCOLCHICINE; 4 AMINOBUTYRIC ACID; AMINOGLYCOSIDE DERIVATIVE; COLCHICINE DERIVATIVE; GLYCINE RECEPTOR; HEXOSE; MUSCLE RELAXANT AGENT; PENTOSE; STRYCHNINE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN; BUCHWALD HARTWIG REACTION; CHEMICAL REACTION; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HEATING; MICROWAVE IRRADIATION; NONHUMAN; POLYMERIZATION; RAT; SPINAL CORD;

ANIMALS; BINDING SITES; CEREBRAL CORTEX; COLCHICINE; GLYCOSIDES; MUSCIMOL; NEUROMUSCULAR AGENTS; RADIOLIGAND ASSAY; RATS; RECEPTORS, GABA; RECEPTORS, GLYCINE; SPINAL CORD; STRYCHNINE;

EID: 33748535110     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm060585t     Document Type: Article

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