New role for spinal stargazin in α-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid receptor-mediated pain sensitization after inflammation

Journal of Neuroscience Research

Volumn 84, Issue 4, 2006, Pages 867-873

  Tao, Feng ^a   Skinner, John ^a   Su, Qingning ^a   Johns, Roger A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antisense technology; Central sensitization; Formalin; Inflammatory pain; Knockdown

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; CALCIUM CHANNEL; MEMBRANE PROTEIN; OLIGODEOXYRIBONUCLEOTIDE; PROTEIN STARGAZIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONFOCAL LASER MICROSCOPY; DRUG MECHANISM; IMMUNOFLUORESCENCE TEST; IMMUNOPRECIPITATION; INFLAMMATION; MALE; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; SPINAL CORD; WESTERN BLOTTING;

6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANALYSIS OF VARIANCE; ANIMALS; CALCIUM CHANNELS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; GENE EXPRESSION REGULATION; IMMUNOPRECIPITATION; INFLAMMATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; MOTOR ACTIVITY; OLIGONUCLEOTIDES, ANTISENSE; PAIN; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; SPINAL CORD;

EID: 33748520630     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.20973     Document Type: Article

References (37)

1. Bleakman D, Lodge D. 1998. Neuropharmacology of AMPA and kainate receptors. Neuropharmacology 37:1187-1204.
2. Bristol LA, Rothstein JD. 1998. Use of antisense oligodeoxynucleotides to inhibit expression of glutamate transporter subtypes. Methods Enzymol 296:514-529.
3. Chen L, Chetkovich DM, Petralia RS, Sweeney NT, Kawasaki Y, Wenthold RJ, Bredt DS, Nicoll RA. 2000. Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms. Nature 408:936-943.
4. Coderre TJ, Van EI. 1994. The utility of excitatory amino acid (EAA) antagonists as analgesic agents. I. Comparison of the antinociceptive activity of various classes of EAA antagonists in mechanical, thermal and chemical nociceptive tests. Pain 59:345-352.
5. Crooke ST. 2000. Progress in antisense technology: the end of the beginning. Methods Enzymol 313:3-45.
6. Crooke ST. 2004a. Antisense strategies. Curr Mol Med 4:465-487.
7. Crooke ST. 2004b. Progress in antisense technology. Annu Rev Med 55:61-95.
8. Garry EM, Moss A, Rosie R, Delaney A, Mitchell R, Fleetwood-Walker SM. 2003. Specific involvement in neuropathic pain of AMPA receptors and adapter proteins for the GluR2 subunit. Mol Cell Neurosci 24:10-22.
9. Hargreaves K, Dubner R, Brown F, Flores C, Joris J. 1988. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32:77-88.
10. Headley PM, Grillner S. 1990. Excitatory amino acids and synaptic transmission: the evidence for a physiological function. Trends Pharmacol Sci 11:205-211.
11. Hollmann M, Heinemann S. 1994. Cloned glutamate receptors. Annu Rev Neurosci 17:31-108.
12. Jakowec MW, Fox AJ, Martin LJ, Kalb RG. 1995. Quantitative and qualitative changes in AMPA receptor expression during spinal cord development. Neuroscience 67:893-907.
13. Jones TL, Sorkin LS. 2004. Calcium-permeable alpha-amino-3-hydroxy-5- methyl-4-isoxazolepropionic acid/kainate receptors mediate development, but not maintenance, of secondary allodynia evoked by first-degree burn in the rat. J Pharmacol Exp Ther 310:223-229.
14. Kim SH, Chung JM. 1992. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 50:355-363.
15. Kontinen VK, Meert TF. 2002. Vocalization responses after intrathecal administration of ionotropic glutamate receptor agonists in rats. Anesth Analg 95:997-1001.
16. Lee IO, Yukhananov R, Standaert DG, Crosby G. 2004. NMDA-R1 antisense oligodeoxynucleotides modify formalin-induced nociception and spinal c-Fos expression in rat spinal cord. Pharmacol Biochem Behav 79:183-188.
17. Minami T, Matsumura S, Okuda-Ashitaka E, Shimamoto K, Sakimura K, Mishina M, Mori H, Ito S. 2001. Characterization of the glutamatergic system for induction and maintenance of allodynia. Brain Res 895:178-185.
18. Neugebauer V, Lucke T, Schaible HG. 1993a. Differential effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on the responses of rat spinal neurons with joint input. Neurosci Lett 155:29-32.
19. Neugebauer V, Lucke T, Schaible HG. 1993b. N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists block the hyperexcitability of dorsal horn neurons during development of acute arthritis in rat's knee joint. J Neurophysiol 70:1365-1377.
20. Neugebauer V, Lucke T, Schaible HG. 1994. Requirement of metabotropic glutamate receptors for the generation of inflammation-evoked hyperexcitability in rat spinal cord neurons. Eur J Neurosci 6:1179-1186.
21. Nishiyama T, Gyermek L, Lee C, Kawasaki-Yatsugi S, Yamaguchi T. 1999a. The spinal antinociceptive effects of a novel competitive AMPA receptor antagonist, YM872, on thermal or formalin-induced pain in rats. Anesth Analg 89:143-147.
22. Nishiyama T, Gyermek L, Lee C, Kawasaki-Yatsugi S, Yamaguchi T. 1999b. The systemically administered competitive AMPA receptor antagonist, YM872, has analgesic effects on thermal or formalin-induced pain in rats. Anesth Analg 89:1534-1537.
23. Nozaki-Taguchi N, Yaksh TL. 2002. Pharmacology of spinal glutamatergic receptors in post-thermal injury-evoked tactile allodynia and thermal hyperalgesia. Anesthesiology 96:617-626.
24. Priel A, Kolleker A, Ayalon G, Gillor M, Osten P, Stern-Bach Y. 2005. Stargazin reduces desensitization and slows deactivation of the AMPA-type glutamate receptors. J Neurosci 25:2682-2686.
25. Sang CN, Hostetter MP, Gracely RH, Chappell AS, Schoepp DD, Lee G, Whitcup S, Caruso R, Max MB. 1998. AMPA/kainate antagonist LY293558 reduces capsaicin-evoked hyperalgesia but not pain in normal skin in humans. Anesthesiology 89:1060-1067.
26. Stanfa LC, Dickenson AH. 1999. The role of non-N-methyl-D-aspartate ionotropic glutamate receptors in the spinal transmission of nociception in normal animals and animals with carrageenan inflammation. Neuroscience 93:1391-1398.
27. Szekely JI, Torok K, Mate G. 2002. The role of ionotropic glutamate receptors in nociception with special regard to the AMPA binding sites. Curr Pharm Des 8:887-912.
28. Tao F, Lu SD, Zhang LM, Huang YL, Sun FY. 2001a. Role of excitatory amino acid transporter 1 in neonatal rat neuronal damage induced by hypoxia-ischemia. Neuroscience 102:503-513.
29. Tao F, Tao YX, Gonzalez JA, Fang M, Mao P, Johns RA. 2001b. Knockdown of PSD-95/SAP90 delays the development of neuropathic pain in rats. Neuroreport 12:3251-3255.
30. Tao F, Tao YX, Mao P, Johns RA. 2003. Role of postsynaptic density protein-95 in the maintenance of peripheral nerve injury-induced neuropathic pain in rats. Neuroscience 117:731-739.
31. Tao F, Tao YX, Zhao C, Dore S, Liaw WJ, Raja SN, Johns RA. 2004. Differential roles of neuronal and endothelial nitric oxide synthases during carrageenan-induced inflammatory hyperalgesia. Neuroscience 128:421-430.
32. Tomita S, Chen L, Kawasaki Y, Petralia RS, Wenthold RJ, Nicoll RA, Bredt DS. 2003. Functional studies and distribution define a family of transmembrane AMPA receptor regulatory proteins. J Cell Biol 161:805-816.
33. Tomita S, Fukata M, Nicoll RA, Bredt DS. 2004. Dynamic interaction of stargazin-like TARPs with cycling AMPA receptors at synapses. Science 303:1508-1511.
34. Tomita S, Adesnik H, Sekiguchi M, Zhang W, Wada K, Howe JR, Nicoll RA, Bredt DS. 2005. Stargazin modulates AMPA receptor gating and trafficking by distinct domains. Nature 435:1052-1058.
35. Turetsky D, Garringer E, Patneau DK. 2005. Stargazin modulates native AMPA receptor functional properties by two distinct mechanisms. J Neurosci 25:7438-7448.
36. Vandenberghe W, Nicoll RA, Bredt DS. 2005. Stargazin is an AMPA receptor auxiliary subunit. Proc Natl Acad Sci U S A 102:485-490.
37. Yamazaki M, Ohno-Shosaku T, Fukaya M, Kano M, Watanabe M, Sakimura K. 2004. A novel action of stargazin as an enhancer of AMPA receptor activity. Neurosci Res 50:369-374.