-
1
-
-
0006117895
-
Therapeutic strategies in Parkinson's disease
-
Jankovic J, Tolosa E, eds. Baltimore, Md: Urban & Schwarzenberg
-
Jankovic J, Marsden CD. Therapeutic strategies in Parkinson's disease. In: Jankovic J, Tolosa E, eds. Parkinson's Disease and Movement Disorders. Baltimore, Md: Urban & Schwarzenberg; 1988;95-119.
-
(1988)
Parkinson's Disease and Movement Disorders
, pp. 95-119
-
-
Jankovic, J.1
Marsden, C.D.2
-
2
-
-
33748503411
-
Pharmacologic management of Parkinson disease: Initial therapy
-
Pahwa R. Pharmacologic management of Parkinson disease: initial therapy. Formulary. 2006;41:4-11.
-
(2006)
Formulary
, vol.41
, pp. 4-11
-
-
Pahwa, R.1
-
3
-
-
33748508232
-
Pharmacologic management of Parkinson disease: Treatment of levodopa-associated "wearing off"
-
Waters CH. Pharmacologic management of Parkinson disease: treatment of levodopa-associated "wearing off." Formulary. 2006;41:12-17.
-
(2006)
Formulary
, vol.41
, pp. 12-17
-
-
Waters, C.H.1
-
4
-
-
0024456653
-
Effects of deprenyl on the progression of disability in early Parkinson's disease
-
Parkinson Study Group. Effects of deprenyl on the progression of disability in early Parkinson's disease. N Engl J Med. 1989;321:1364-1371.
-
(1989)
N Engl J Med
, vol.321
, pp. 1364-1371
-
-
-
5
-
-
0027530638
-
Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease
-
Parkinson Study Group. Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease. N Engl J Med. 1993;328:176-183.
-
(1993)
N Engl J Med
, vol.328
, pp. 176-183
-
-
-
6
-
-
9044226896
-
Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP patients requiring levodopa
-
Parkinson Study Group. Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP patients requiring levodopa. Ann Neurol. 1996;39:37-45.
-
(1996)
Ann Neurol
, vol.39
, pp. 37-45
-
-
-
7
-
-
0030042620
-
Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP subjects not requiring levodopa
-
Parkinson Study Group. Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP subjects not requiring levodopa. Ann Neurol. 1996;39:29-36.
-
(1996)
Ann Neurol
, vol.39
, pp. 29-36
-
-
-
8
-
-
0347635418
-
Neuroprotection by monoamine oxidase B inhibitors: A therapeutic strategy for Parkinson's disease?
-
Tabakman R, Lecht S, Lazarovici P. Neuroprotection by monoamine oxidase B inhibitors: a therapeutic strategy for Parkinson's disease? Bioessays. 2004;26:80-90.
-
(2004)
Bioessays
, vol.26
, pp. 80-90
-
-
Tabakman, R.1
Lecht, S.2
Lazarovici, P.3
-
10
-
-
0031037786
-
L-(-)-desmethylselegiline, a metabolite of selegiline [L-(-)-deprenyl], protects mesencephalic dopamine neurons from excitotoxicity in vitro
-
Mytilineou C, Radcliffe PM, Olanow CW. L-(-)-desmethylselegiline, a metabolite of selegiline [L-(-)-deprenyl], protects mesencephalic dopamine neurons from excitotoxicity in vitro. J Neurochem. 1997;68:434-436.
-
(1997)
J Neurochem
, vol.68
, pp. 434-436
-
-
Mytilineou, C.1
Radcliffe, P.M.2
Olanow, C.W.3
-
11
-
-
0028181797
-
(-)-Deprenyl alters the survival of adult murine facial motoneurons after axotomy: Increases in vulnerable C57BL strain but decreases in motor neuron degeneration mutants
-
Oh C, Murray B, Bhattacharya N, Hollard D, Tatton WG. (-)-Deprenyl alters the survival of adult murine facial motoneurons after axotomy: increases in vulnerable C57BL strain but decreases in motor neuron degeneration mutants. J Neurosci Res. 1994;38;64-74.
-
(1994)
J Neurosci Res
, vol.38
, pp. 64-74
-
-
Oh, C.1
Murray, B.2
Bhattacharya, N.3
Hollard, D.4
Tatton, W.G.5
-
12
-
-
0037059430
-
Trembovler Neuroprotective and neurotoxic effects of monoamine oxidase-B inhibitors and derived metabolites under ischemia in PC12 cells
-
Abu-Raya S, Tabakman R, Blaugrund E, Trembovler B, Lazarovici P. Trembovler Neuroprotective and neurotoxic effects of monoamine oxidase-B inhibitors and derived metabolites under ischemia in PC12 cells. Eur J Pharmacol. 2002;434:109-116.
-
(2002)
Eur J Pharmacol
, vol.434
, pp. 109-116
-
-
Abu-Raya, S.1
Tabakman, R.2
Blaugrund, E.3
Trembovler, B.4
Lazarovici, P.5
-
13
-
-
0035130289
-
Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B
-
Youdim MB, Gross A, Finberg JP. Rasagiline [N-propargyl-1R(+)-aminoindan] , a selective and potent inhibitor of mitochondrial monoamine oxidase B. Br J Pharmacol. 2001;132:500-506.
-
(2001)
Br J Pharmacol
, vol.132
, pp. 500-506
-
-
Youdim, M.B.1
Gross, A.2
Finberg, J.P.3
-
14
-
-
1542317394
-
Contrasting neuroprotective and neurotoxic actions of respective metabolites of anti-Parkinson drugs rasagiline and selegiline
-
Am OB, Amit T, Youdim B. Contrasting neuroprotective and neurotoxic actions of respective metabolites of anti-Parkinson drugs rasagiline and selegiline. Neurosci Lett. 2004;355:169-172.
-
(2004)
Neurosci Lett
, vol.355
, pp. 169-172
-
-
Am, O.B.1
Amit, T.2
Youdim, B.3
-
15
-
-
0033231244
-
Rasagiline, a monoamine oxidase-B inhibitor, protects NGF-differentiated PC12 cells against oxygen-glucose deprivation
-
Abu-Raya S, Blaugrund E, Trembovler V, Shilderman-Bloch E, Shohami E, Lazarovici P. Rasagiline, a monoamine oxidase-B inhibitor, protects NGF-differentiated PC12 cells against oxygen-glucose deprivation. J Neurosci Res. 1999;58:456-463.
-
(1999)
J Neurosci Res
, vol.58
, pp. 456-463
-
-
Abu-Raya, S.1
Blaugrund, E.2
Trembovler, V.3
Shilderman-Bloch, E.4
Shohami, E.5
Lazarovici, P.6
-
16
-
-
0032498811
-
Increased survival of dopaminergic neurons by rasagiline, a monoamine oxidase B inhibitor
-
Finberg JP, Takeshima T, Johnston JM, Commissiong JW. Increased survival of dopaminergic neurons by rasagiline, a monoamine oxidase B inhibitor. Neuroreport. 1998;9:703-707.
-
(1998)
Neuroreport
, vol.9
, pp. 703-707
-
-
Finberg, J.P.1
Takeshima, T.2
Johnston, J.M.3
Commissiong, J.W.4
-
17
-
-
0034526673
-
The neuronal survival effects of rasagiline and deprenyl on fetal human and rat ventral mesencephalic neurons in culture
-
Goggi J, Theofilopoulos S, Riaz SS, Jauniaux E, Stern GM, Bradfrod HF. The neuronal survival effects of rasagiline and deprenyl on fetal human and rat ventral mesencephalic neurons in culture. Neuroreport. 2000;11:3937-3941.
-
(2000)
Neuroreport
, vol.11
, pp. 3937-3941
-
-
Goggi, J.1
Theofilopoulos, S.2
Riaz, S.S.3
Jauniaux, E.4
Stern, G.M.5
Bradfrod, H.F.6
-
18
-
-
0032999575
-
Neuroprotective effect of rasagiline, a selective monoamine oxidase-B inhibitor, against closed head injury in the mouse
-
Huang W, Chen Y, Shohami E, Weinstock M. Neuroprotective effect of rasagiline, a selective monoamine oxidase-B inhibitor, against closed head injury in the mouse. Eur J Pharmacol. 1999;366:127-135.
-
(1999)
Eur J Pharmacol
, vol.366
, pp. 127-135
-
-
Huang, W.1
Chen, Y.2
Shohami, E.3
Weinstock, M.4
-
19
-
-
0032807402
-
Studies with rasagiline, a MAO-B inhibitor, in experimental focal ischemia in the rat
-
Speiser Z, Mayk AA, Eliash S, Cohen S. Studies with rasagiline, a MAO-B inhibitor, in experimental focal ischemia in the rat. J Neural Transm. 1999;106:593-606.
-
(1999)
J Neural Transm
, vol.106
, pp. 593-606
-
-
Speiser, Z.1
Mayk, A.A.2
Eliash, S.3
Cohen, S.4
-
20
-
-
2342547676
-
Neuroprotective effect of rasagiline in a rodent model of Parkinson's disease
-
Blandini F, Armentero MT, Fancellu R, Blaugrund E, Nappi G. Neuroprotective effect of rasagiline in a rodent model of Parkinson's disease. Exp Neurol. 2004;187:455-459.
-
(2004)
Exp Neurol
, vol.187
, pp. 455-459
-
-
Blandini, F.1
Armentero, M.T.2
Fancellu, R.3
Blaugrund, E.4
Nappi, G.5
-
21
-
-
0642345197
-
The essentiality of Bcl-2, PKC and proteasome-ubiquitin complex activations in the neuroprotective-antiapoptotic action of the anti-Parkinson drug, rasagiline
-
Youdim MB, Amit T, Yogev-Falach M, Am OB, Maruyama W, Naoi M. The essentiality of Bcl-2, PKC and proteasome-ubiquitin complex activations in the neuroprotective-antiapoptotic action of the anti-Parkinson drug, rasagiline. Biochem Pharmacol. 2003;66:1635-1641.
-
(2003)
Biochem Pharmacol
, vol.66
, pp. 1635-1641
-
-
Youdim, M.B.1
Amit, T.2
Yogev-Falach, M.3
Am, O.B.4
Maruyama, W.5
Naoi, M.6
-
22
-
-
0032101092
-
Sparing by rasagiline (TVP-1012) of cholinergic functions and behavior in the postnatal anoxia rat
-
Speiser Z, Katzir O, Rehavi M, Zabarski T, Cohen S. Sparing by rasagiline (TVP-1012) of cholinergic functions and behavior in the postnatal anoxia rat. Pharmacol Biochem Behav. 1998;60:387-393.
-
(1998)
Pharmacol Biochem Behav
, vol.60
, pp. 387-393
-
-
Speiser, Z.1
Katzir, O.2
Rehavi, M.3
Zabarski, T.4
Cohen, S.5
-
23
-
-
0034871806
-
Monoamine oxidase-inhibition and MPTP-induced neurotoxicity in the nonhuman primate: Comparison of rasagiline (TVP 1012) with selegiline
-
Kupsch A, Sautter J, Gotz ME, et al. Monoamine oxidase-inhibition and MPTP-induced neurotoxicity in the nonhuman primate: comparison of rasagiline (TVP 1012) with selegiline. J Neural Transm. 2001;108:985-1009.
-
(2001)
J Neural Transm
, vol.108
, pp. 985-1009
-
-
Kupsch, A.1
Sautter, J.2
Gotz, M.E.3
-
24
-
-
0036677312
-
Mitochondrial permeability transition mediates apoptosis induced by N-methyl(R)salsolinol, an endogenous neurotoxin, and is inhibited by Bcl-2 and rasagiline, N-propargyl-1(R)-aminoindan
-
Akao Y, Maruyama W, Shimizu S, et al. Mitochondrial permeability transition mediates apoptosis induced by N-methyl(R)salsolinol, an endogenous neurotoxin, and is inhibited by Bcl-2 and rasagiline, N-propargyl-1(R)- aminoindan. J Neurochem. 2002;82:913-923.
-
(2002)
J Neurochem
, vol.82
, pp. 913-923
-
-
Akao, Y.1
Maruyama, W.2
Shimizu, S.3
-
25
-
-
0034525891
-
Neurotoxins induce apoptosis in dopamine neurons: Protection by N-propargylamine-1R-and (S)-aminoindan, rasagiline, and TV 1022
-
Maruyama W, Akao Y, Youdim MB, Naoi M. Neurotoxins induce apoptosis in dopamine neurons: protection by N-propargylamine-1R-and (S)-aminoindan, rasagiline, and TV 1022. J Neural Transm. 2000;60(suppl):171-186.
-
(2000)
J Neural Transm
, vol.60
, pp. 171-186
-
-
Maruyama, W.1
Akao, Y.2
Youdim, M.B.3
Naoi, M.4
-
26
-
-
2642529309
-
Regulation of protein kinase C by the anti-Parkinson drug, MAO-B inhibitor, rasagiline and its derivatives, in vivo
-
Bar-Am O, Yogev-Falach M, Amit T, Sagi Y, Youdim MB. Regulation of protein kinase C by the anti-Parkinson drug, MAO-B inhibitor, rasagiline and its derivatives, in vivo. J Neurochem. 2004;89:1119-1125.
-
(2004)
J Neurochem
, vol.89
, pp. 1119-1125
-
-
Bar-Am, O.1
Yogev-Falach, M.2
Amit, T.3
Sagi, Y.4
Youdim, M.B.5
-
27
-
-
0036229947
-
Propargylamines induce anti-apoptotic new protein synthesis in serum- and nerve growth factor (NGF)-withdrawn, NGF-differentiated PC-12 cells
-
Tatton WG, Chalmers-Redman RM, Ju WJ, et al. Propargylamines induce anti-apoptotic new protein synthesis in serum- and nerve growth factor (NGF)-withdrawn, NGF-differentiated PC-12 cells. J Pharmacol Exp Ther. 2002;301:753-764.
-
(2002)
J Pharmacol Exp Ther
, vol.301
, pp. 753-764
-
-
Tatton, W.G.1
Chalmers-Redman, R.M.2
Ju, W.J.3
-
28
-
-
0037189081
-
An anti-Parkinson's disease drug, N-propargyl-1(R)-aminoindan (rasagiline), enhances expression of anti-apoptotic Bcl-2 in human dopaminergic SH-SY5Y cells
-
Akao Y, Maruyama W, Yi H, Shamoto-Nagai M, Youdim MB, Naoi M. An anti-Parkinson's disease drug, N-propargyl-1(R)-aminoindan (rasagiline), enhances expression of anti-apoptotic Bcl-2 in human dopaminergic SH-SY5Y cells. Neurosci Lett. 2002;326:105-108.
-
(2002)
Neurosci Lett
, vol.326
, pp. 105-108
-
-
Akao, Y.1
Maruyama, W.2
Yi, H.3
Shamoto-Nagai, M.4
Youdim, M.B.5
Naoi, M.6
-
29
-
-
0036777108
-
The involvement of mitogen-activated protein (MAP) kinase in the regulation of amyloid precursor protein processing by novel cholinesterase inhibitors derived from rasagiline
-
Yogev-Falach M, Amit T, Bar-Am O, Weinstock M, Youdim MB. The involvement of mitogen-activated protein (MAP) kinase in the regulation of amyloid precursor protein processing by novel cholinesterase inhibitors derived from rasagiline. FASEB J. 2002;16:1674-1676.
-
(2002)
FASEB J
, vol.16
, pp. 1674-1676
-
-
Yogev-Falach, M.1
Amit, T.2
Bar-Am, O.3
Weinstock, M.4
Youdim, M.B.5
-
30
-
-
0034705512
-
Enhancing effect of rasagiline on superoxide dismutase and catalase activities in the dopaminergic system in the rat
-
Carrillo MC, Minami C, Kitani K, et al. Enhancing effect of rasagiline on superoxide dismutase and catalase activities in the dopaminergic system in the rat. Life Sci. 2000;67:577-585.
-
(2000)
Life Sci
, vol.67
, pp. 577-585
-
-
Carrillo, M.C.1
Minami, C.2
Kitani, K.3
-
31
-
-
0034884148
-
Transfection-enforced Bcl-2 overexpression and an anti-Parkinson drug, rasagiline, prevent nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase induced by an endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol
-
Maruyama W, Akao Y, Youdim MB, Davis BA, Naoi M. Transfection-enforced Bcl-2 overexpression and an anti-Parkinson drug, rasagiline, prevent nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase induced by an endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol. J Neurochem. 2001;78:727-735.
-
(2001)
J Neurochem
, vol.78
, pp. 727-735
-
-
Maruyama, W.1
Akao, Y.2
Youdim, M.B.3
Davis, B.A.4
Naoi, M.5
-
32
-
-
0035800214
-
GAPDH knockdown rescues mesencephalic dopaminergic neurons from MPP+-induced apoptosis
-
Fukuhara Y, Takeshima T, Kashiwaya Y, Shimoda K, Ishitani R, Nakashima K. GAPDH knockdown rescues mesencephalic dopaminergic neurons from MPP+-induced apoptosis. Neuroreport. 2001;12:2049-2052.
-
(2001)
Neuroreport
, vol.12
, pp. 2049-2052
-
-
Fukuhara, Y.1
Takeshima, T.2
Kashiwaya, Y.3
Shimoda, K.4
Ishitani, R.5
Nakashima, K.6
-
33
-
-
0346848857
-
N-propargyl-1 (R)-aminoindan, rasagiline, increases glial cell line-derived neurotrophic factor (GDNF) in neuroblastoma SH-SY5Y cells through activation of NF-kappa-B transcription factor
-
Maruyama W, Nitta A, Shamoto-Nagai M, et al. N-Propargyl-1 (R)-aminoindan, rasagiline, increases glial cell line-derived neurotrophic factor (GDNF) in neuroblastoma SH-SY5Y cells through activation of NF-kappa-B transcription factor. Neurochem Int. 2004;44:393-400.
-
(2004)
Neurochem Int
, vol.44
, pp. 393-400
-
-
Maruyama, W.1
Nitta, A.2
Shamoto-Nagai, M.3
-
34
-
-
2342655732
-
A controlled, randomized, delayed-start study of rasagiline in early Parkinson's disease
-
Parkinson Study Group. A controlled, randomized, delayed-start study of rasagiline in early Parkinson's disease. Arch Neurol. 2004;61:561-566.
-
(2004)
Arch Neurol
, vol.61
, pp. 561-566
-
-
-
35
-
-
0036894795
-
A controlled trial of rasagiline in early Parkinson disease: The TEMPO Study
-
Parkinson Study Group. A controlled trial of rasagiline in early Parkinson disease: the TEMPO Study. Arch Neurol. 2002;59:1937-1943.
-
(2002)
Arch Neurol
, vol.59
, pp. 1937-1943
-
-
|