CCR4 participation in Th type 1 (mycobacterial) and Th type 2 (schistosomal) anamnestic pulmonary granulomatous responses

Journal of Immunology

Volumn 177, Issue 6, 2006, Pages 4149-4158

  Freeman, Christine M ^a   Stolberg, Valerie R ^b   Chiu, Bo Chin ^a   Lukacs, Nicholas W ^a   Kunkel, Steven L ^a   Chensue, Stephen W ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CHEMOKINE CCL22; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR4; GAMMA INTERFERON; INTERLEUKIN 4; MYCOBACTERIUM ANTIGEN; PARASITE ANTIGEN; TUBERCULIN; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELL FUNCTION; CHEMOTAXIS; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; EFFECTOR CELL; LUNG GRANULOMA; MOUSE; MYCOBACTERIUM; NONHUMAN; PRIORITY JOURNAL; SCHISTOSOMA; TH1 CELL; TH2 CELL;

EID: 33748477501     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.177.6.4149     Document Type: Article

References (48)

1. Santana, M. A., and Y. Rosenstein. 2003. What it takes to become an effector T cell: the process, the cells involved, and the mechanisms. J. Cell. Physiol. 195: 392-401.
2. Mosmann, T. R., and R. L. Coffman. 1989. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7: 145-173.
3. Campbell, D. J., G. F. Debes, B. Johnston, E. Wilson, and E. C. Butcher. 2003. Targeting T cell responses by selective chemokine receptor expression. Semin. Immunol. 15: 277-286.
4. O'Garra, A., L. M. McEvoy, and A. Zlotnik. 1998. T-cell subsets: chemokine receptors guide the way. Curr. Biol. 8: R646-R649.
5. Qin, S., J. B. Rottman, P. Myers, N. Kassam, M. Weinblatt, M. Loetscher, A. E. Koch, B. Moser, and C. R. Mackay. 1998. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. J. Clin. Invest. 101: 746-754.
6. Bonecchi, R., G. Bianchi, P. P. Bordignon, D. D'Ambrosio, R. Lang, A. Borsatti, S. Sozzani, P. Allavena, P. A. Gray, A. Mantovani, and F. Sinigaglia. 1998. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J. Exp. Med. 187: 129-134.
7. Loetscher, P., M. Uguccioni, L. Bordoli, M. Baggiolini, B. Moser, C. Chizzolini, and J. M. Dayer. 1998. CCR5 is characteristic of Th1 lymphocytes. Nature 391: 344-345.
8. Sallusto, F., C. R. Mackay, and A. Lanzavecchia. 1997. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science 277: 2005-2007.
9. Imai, T., M. Nagira, S. Takagi, M. Kakizaki, M. Nishimura, J. Wang, P. W. Gray, K. Matsushima, and O. Yoshie. 1999. Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine. Int. Immunol. 11: 81-88.
10. D'Ambrosio, D., A. Iellem, R. Bonecchi, D. Mazzeo, S. Sozzani, A. Mantovani, and F. Sinigaglia. 1998. Selective up-regulation of chemokine receptors CCR4 and CCR8 upon activation of polarized human type 2 Th cells. J. Immunol. 161: 5111-5115.
11. Zingoni, A., H. Soto, J. A. Hedrick, A. Stoppacciaro, C. T. Storlazzi, F. Sinigaglia, D. D'Ambrosio, A. O'Garra, D. Robinson, M. Rocchi, et al. 1998. The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells. J. Immunol. 161: 547-551.
12. + T cells, which regulate Th2-mediated granuloma formation in mice. J. Immunol. 174: 1962-1970.
13. Panina-Bordignon, P., A. Papi, M. Mariani, P. Di Lucia, G. Casoni, C. Bellettato, C. Buonsanti, D. Miotto, C. Mapp, A. Villa, et al. 2001. The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics. J. Clin. Invest. 107: 1357-1364.
14. Nouri-Aria, K. T., D. Wilson, J. N. Francis, L. A. Jopling, M. R. Jacobson, M. R. Hodge, D. P. Andrew, S. J. Till, E. M. Varga, T. J. Williams, et al. 2002. CCR4 in human allergen-induced late responses in the skin and lung. Eur. J. Immunol. 32: 1933-1938.
15. + T cells. J. Leukocyte Biol. 68: 568-574.
16. Chvatchko, Y., A. J. Hoogewerf, A. Meyer, S. Alouani, P. Juillard, R. Buser, F. Conquet, A. E. Proudfoot, T. N. Wells, and C. A. Power. 2000. A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock. J. Exp. Med. 191: 1755-1764.
17. Andrew, D. P., N. Ruffing, C. H. Kim, W. Miao, H. Heath, Y. Li, K. Murphy, J. J. Campbell, E. C. Butcher, and L. Wu. 2001. C-C chemokine receptor 4 expression defines a major subset of circulating nonintestinal memory T cells of both Th1 and Th2 potential. J. Immunol. 166: 103-111.
18. + suppressor T cells. Eur. J. Immunol. 33: 1488-1496.
19. Imai, T., D. Chantry, C. J. Raport, C. L. Wood, M. Nishimura, R. Godiska, O. Yoshie, and P. W. Gray. 1998. Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4. J. Biol. Chem. 273: 1764-1768.
20. + T cells. Eur. J. Immunol. 29: 2684-2694.
21. Schaniel, C., F. Sallusto, C. Ruedl, P. Sideras, F. Melchers, and A. G. Rolink. 1999. Three chemokines with potential functions in T lymphocyte-independent and -dependent B lymphocyte stimulation. Eur. J. Immunol. 29: 2934-2947.
22. Boehlen, F., and K. J. Clemetson. 2001. Platelet chemokines and their receptors: what is their relevance to platelet storage and transfusion practice? Transfus. Med. 11: 403-417.
23. Belperio, J. A., M. Dy, L. Murray, M. D. Burdick, Y. Y. Xue, R. M. Strieter, and M. P. Keane. 2004. The role of the Th2 CC chemokine ligand CCL17 in pulmonary fibrosis. J. Immunol. 173: 4692-4698.
24. Inngjerdingen, M., B. Damaj, and A. A. Maghazachi. 2000. Human NK cells express CC chemokine receptors 4 and 8 and respond to thymus and activation-regulated chemokine, macrophage-derived chemokine, and I-309. J. Immunol. 164: 4048-4054.
25. Sallusto, F., and A. Lanzavecchia. 1999. Mobilizing dendritic cells for tolerance, priming, and chronic inflammation. J. Exp. Med. 189: 611-614.
26. Chensue, S. W., K. Warmington, J. H. Ruth, N. Lukacs, and S. L. Kunkel. 1997. Mycobacterial and schistosomal antigen-elicited granuloma formation in IFN-γ and IL-4 knockout mice: analysis of local and regional cytokine and chemokine networks. J. Immunol. 159: 3565-3573.
27. Baekkevold, E. S., M. A. Wurbel, P. Kivisakk, C. M. Wain, C. A. Power, G. Haraldsen, and J. J. Campbell. 2005. A role for CCR4 in development of mature circulating cutaneous T helper memory cell populations. J. Exp. Med. 201: 1045-1051.
28. Chensue, S. W., N. W. Lukacs, T. Y. Yang, X. Shang, K. A. Frait, S. L. Kunkel, T. Kung, M. T. Wiekowski, J. A. Hedrick, D. N. Cook, et al. 2001. Aberrant in vivo T helper type 2 cell response and impaired eosinophil recruitment in CC chemokine receptor 8 knockout mice. J. Exp. Med. 193: 573-584.
29. + T cell chemokine receptor transcript expression during in vivo type-1 (mycobacterial) and type-2 (schistosomal) immune responses. J. Leukocyte Biol. 72: 363-372.
30. Tang, H. L., and J. G. Cyster. 1999. Chemokine up-regulation and activated T cell attraction by maturing dendritic cells. Science 284: 819-822.
31. + cells of memory phenotype. Eur. J. Immunol. 27: 2225-2232.
32. Kim, C. H., L. Rott, E. J. Kunkel, M. C. Genovese, D. P. Andrew, L. Wu, and E. C. Butcher. 2001. Rules of chemokine receptor association with T cell polarization in vivo. J. Clin. Invest. 108: 1331-1339.
33. Chiu, B. C., C. M. Freeman, V. R. Stolberg, J. S. Hu, E. Komuniecki, and S. W. Chensue. 2004. The innate pulmonary granuloma: characterization and demonstration of dendritic cell recruitment and function. Am. J. Pathol. 164: 1021-1030.
34. Penna, G., S. Sozzani, and L. Adorini. 2001. Cutting edge: selective usage of chemokine receptors by plasmacytoid dendritic cells. J. Immunol. 167: 1862-1866.
35. Chiu, B. C., C. M. Freeman, V. R. Stolberg, J. S. Hu, K. Zeibecoglou, B. Lu, C. Gerard, I. F. Charo, S. A. Lira, and S. W. Chensue. 2004. Impaired lung dendritic cell activation in CCR2 knockout mice. Am. J. Pathol. 165: 1199-1209.
36. Katou, F., H. Ohtani, T. Nakayama, K. Ono, K. Matsushima, A. Saaristo, H. Nagura, O. Yoshie, and K. Motegi. 2001. Macrophage-derived chemokine (MDC/CCL22) and CCR4 are involved in the formation of T lymphocyte-dendritic cell clusters in human inflamed skin and secondary lymphoid tissue. Am. J. Pathol. 158: 1263-1270.
37. Gonzalo, J. A., Y. Pan, C. M. Lloyd, G. Q. Jia, G. Yu, B. Dussault, C. A. Powers, A. E. Proudfoot, A. J. Coyle, D. Gearing, and J. C. Gutierrez-Ramos. 1999. Mouse monocyte-derived chemokine is involved in airway hyperreactivity and lung inflammation. J. Immunol. 163: 403-411.
38. Jakubzick, C., H. Wen, A. Matsukawa, M. Keller, S. L. Kunkel, and C. M. Hogaboam. 2004. Role of CCR4 ligands, CCL17 and CCL22, during Schistosoma mansoni egg-induced pulmonary granuloma formation in mice. Am. J. Pathol. 165: 1211-1221.
39. Kunkel, E. J., J. Boisvert, K. Murphy, M. A. Vierra, M. C. Genovese, A. J. Wardlaw, H. B. Greenberg, M. R. Hodge, L. Wu, E. C. Butcher, and J. J. Campbell. 2002. Expression of the chemokine receptors CCR4, CCR5, and CXCR3 by human tissue-infiltrating lymphocytes. Am. J. Pathol. 160: 347-355.
40. Godiska, R., D. Chantry, C. J. Raport, S. Sozzani, P. Allavena, D. Leviten, A. Mantovani, and P. W. Gray. 1997. Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells. J. Exp. Med. 185: 1595-1604.
41. Wu, M., H. Fang, and S. T. Hwang. 2001. Cutting edge: CCR4 mediates antigen-primed T cell binding to activated dendritic cells. J. Immunol. 167: 4791-4795.
42. + T cell response. J. Exp. Med. 201: 1555-1565.
43. Conroy, D. M., L. A. Jopling, C. M. Lloyd, M. R. Hodge, D. P. Andrew, T. J. Williams, J. E. Pease, and I. Sabroe. 2003. CCR4 blockade does not inhibit allergic airways inflammation. J. Leukocyte Biol. 74: 558-563.
44. Annunziato, F., L. Cosmi, G. Galli, C. Beltrame, P. Romagnani, R. Manetti, S. Romagnani, and E. Maggi. 1999. Assessment of chemokine receptor expression by human Th1 and Th2 cells in vitro and in vivo. J. Leukocyte Biol. 65: 691-699.
45. Hu, J. S., C. M. Freeman, V. R. Stolberg, B. Chiu, G. J. Bridger, S. P. Ficker, N. W. Lukacs, and S. W. Chensue. 2006. AMD3465, a novel CXCR4 receptor antagonist, abrogates schistosomal Ag-elicited (type-2) pulmonary granuloma formation. Am. J. Pathol. 169: 424-432.
46. H1 cells have differential capacities for memory cell generation in vivo. Nat. Immunol. 3: 852-858.
47. Zhang, X., T. Brunner, L. Carter, R. W. Dutton, P. Rogers, L. Bradley, T. Sato, J. C. Reed, D. Green, and S. L. Swain. 1997. Unequal death in T helper cell (Th)1 and Th2 effectors: Th1, but not Th2, effectors undergo rapid Fas/FasL-mediated apoptosis. J. Exp. Med. 185: 1837-1849.
48. Randolph, D. A., G. Huang, C. J. Carruthers, L. E. Bromley, and D. D. Chaplin. 1999. The role of CCR7 in TH1 and TH2 cell localization and delivery of B cell help in vivo. Science 286: 2159-2162.