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Volumn 18, Issue 10, 2006, Pages 757-766

Involvement of the Ser-Glu-Pro motif in ligand species-dependent desensitisation of the rat gonadotrophin-releasing hormone receptor

Author keywords

C terminaltail; Desensitisation; GnRH receptor; Ligand; Ser Glu Promotif

Indexed keywords

CALCIUM ION; GLUTAMINE; GONADORELIN; GONADORELIN I; GONADORELIN II; GONADORELIN RECEPTOR; GREEN FLUORESCENT PROTEIN; INOSITOL PHOSPHATE; MUTANT PROTEIN; PROLINE; SERINE; UNCLASSIFIED DRUG; VALINE;

EID: 33748471175     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/j.1365-2826.2006.01469.x     Document Type: Article
Times cited : (3)

References (52)
  • 1
    • 0028092770 scopus 로고
    • Gonadotropin releasing hormone receptors: Structure and signal transduction pathways
    • Stojilkovic SS, Reinhart J, Catt KJ. Gonadotropin releasing hormone receptors: Structure and signal transduction pathways. Endocr Rev 1994; 15: 462-499.
    • (1994) Endocr Rev , vol.15 , pp. 462-499
    • Stojilkovic, S.S.1    Reinhart, J.2    Catt, K.J.3
  • 3
    • 0011305311 scopus 로고
    • Identification of the second gonadotropin-releasing hormone in chicken hypothalamus: Evidence that gonadotropin secretion is probably controlled by two distinct gonadotropin-releasing hormones in avian species
    • Miyamoto K, Hasegawa Y, Nomura M, Igarashi M, Kangawa K, Matsuo H. Identification of the second gonadotropin-releasing hormone in chicken hypothalamus: Evidence that gonadotropin secretion is probably controlled by two distinct gonadotropin-releasing hormones in avian species. Proc Natl Acad Sci USA 1984; 81: 3874-3878.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 3874-3878
    • Miyamoto, K.1    Hasegawa, Y.2    Nomura, M.3    Igarashi, M.4    Kangawa, K.5    Matsuo, H.6
  • 4
    • 0027996738 scopus 로고
    • Lovejoy DA, Sherwood NM. Three forms of gonadotropin-releasing hormone characterized from brains of one species
    • Powell JF, Zohar Y, Elizur A, Park M, Fischer WH, Craig AG, Rivier JE. Lovejoy DA, Sherwood NM. Three forms of gonadotropin-releasing hormone characterized from brains of one species. Proc Natl Acad Sci USA 1994; 91: 12081-12085.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12081-12085
    • Powell, J.F.1    Zohar, Y.2    Elizur, A.3    Park, M.4    Fischer, W.H.5    Craig, A.G.6    Rivier, J.E.7
  • 5
    • 0032815546 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone genes. phylogeny, structure, and functions
    • Fernald RD, White RB. Gonadotropin-releasing hormone genes. phylogeny, structure, and functions. Front Neuroendocrinol 1999; 20: 224-240.
    • (1999) Front Neuroendocrinol , vol.20 , pp. 224-240
    • Fernald, R.D.1    White, R.B.2
  • 6
    • 0015251023 scopus 로고
    • Primary structure of the ovine hypothalamic luteinizing hormone-releasing factor (LHF) (LH-hypothalamus-LRF gas chromatography-mass spectrometry-decapeptide-Edman degradation)
    • Burgus R, Butcher M, Amoss M, Ling N, Monahan M, Rivier J, Fellows R, Blackwell R, Vale W, Guillemin R. Primary structure of the ovine hypothalamic luteinizing hormone-releasing factor (LHF) (LH-hypothalamus-LRF gas chromatography-mass spectrometry-decapeptide-Edman degradation). Proc Natl Acad Sci USA 1972; 69: 278-282.
    • (1972) Proc Natl Acad Sci USA , vol.69 , pp. 278-282
    • Burgus, R.1    Butcher, M.2    Amoss, M.3    Ling, N.4    Monahan, M.5    Rivier, J.6    Fellows, R.7    Blackwell, R.8    Vale, W.9    Guillemin, R.10
  • 8
    • 0032982686 scopus 로고    scopus 로고
    • Regional expression of mRNA encoding a second form of gonadotropin-releasing hormone in the macaque brain
    • Urbanski HF, White RB, Fernald RD, Kohama SG, Garyfallou VT, Densmore VS. Regional expression of mRNA encoding a second form of gonadotropin-releasing hormone in the macaque brain. Endocrinology 1999; 140: 1945-1948.
    • (1999) Endocrinology , vol.140 , pp. 1945-1948
    • Urbanski, H.F.1    White, R.B.2    Fernald, R.D.3    Kohama, S.G.4    Garyfallou, V.T.5    Densmore, V.S.6
  • 9
    • 0030916226 scopus 로고    scopus 로고
    • Chicken GnRH II-like peptides and a GnRH receptor selective for chicken GnRH II in amphibian sympathetic ganglia
    • Troskie B, King JA, Millar RP, Peng YY, Kim J, Figueras H, Illing N. Chicken GnRH II-like peptides and a GnRH receptor selective for chicken GnRH II in amphibian sympathetic ganglia. Neuroendocrinology 1997; 65: 396-402.
    • (1997) Neuroendocrinology , vol.65 , pp. 396-402
    • Troskie, B.1    King, J.A.2    Millar, R.P.3    Peng, Y.Y.4    Kim, J.5    Figueras, H.6    Illing, N.7
  • 10
    • 0026794339 scopus 로고
    • Molecular cloning and expression of cDNA encoding the murine gonadotropin-releasing hormone receptor
    • Reinhart J, Mertz LM, Catt KJ. Molecular cloning and expression of cDNA encoding the murine gonadotropin-releasing hormone receptor. J Biol Chem 1992; 267: 21281-21284.
    • (1992) J Biol Chem , vol.267 , pp. 21281-21284
    • Reinhart, J.1    Mertz, L.M.2    Catt, K.J.3
  • 13
    • 0030937284 scopus 로고    scopus 로고
    • Molecular mechanisms of ligand interaction with the gonadotropin-releasing hormone receptor
    • Sealfon SC, Weinstein H, Millar RP. Molecular mechanisms of ligand interaction with the gonadotropin-releasing hormone receptor. Endocr Rev 1997; 18: 180-205.
    • (1997) Endocr Rev , vol.18 , pp. 180-205
    • Sealfon, S.C.1    Weinstein, H.2    Millar, R.P.3
  • 15
    • 0033515025 scopus 로고    scopus 로고
    • Two gonadotropin-releasing hormone receptor subtypes with distinct ligand selectivity and differential distribution in brain and pituitary in the goldfish (Carassius auratus)
    • Illing N, Troskie BE, Nahorniak CS, Hapgood JP, Peter RE, Millar RP. Two gonadotropin-releasing hormone receptor subtypes with distinct ligand selectivity and differential distribution in brain and pituitary in the goldfish (Carassius auratus). Proc Natl Acad Sci USA 1999; 96: 2526-2531.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2526-2531
    • Illing, N.1    Troskie, B.E.2    Nahorniak, C.S.3    Hapgood, J.P.4    Peter, R.E.5    Millar, R.P.6
  • 18
    • 0034810482 scopus 로고    scopus 로고
    • A gonadotropin-releasing hormone (GnRH) receptor specific for GnRH II in primates
    • Neill JD, Duck LW, Sellers JC, Musgrove LC. A gonadotropin-releasing hormone (GnRH) receptor specific for GnRH II in primates. Biochem Biophys Res Commun 2001; 282: 1012-1018.
    • (2001) Biochem Biophys Res Commun , vol.282 , pp. 1012-1018
    • Neill, J.D.1    Duck, L.W.2    Sellers, J.C.3    Musgrove, L.C.4
  • 19
    • 0034756120 scopus 로고    scopus 로고
    • The genes encoding the type-II gonadotropin-releasing hormone receptor and the ribonucleoprotein RBM8A in humans overlap in two genomic loci
    • Faurholm B, Millar RP, Katz AA. The genes encoding the type-II gonadotropin-releasing hormone receptor and the ribonucleoprotein RBM8A in humans overlap in two genomic loci. Genomics 2001; 78: 15-18.
    • (2001) Genomics , vol.78 , pp. 15-18
    • Faurholm, B.1    Millar, R.P.2    Katz, A.A.3
  • 20
    • 85047684264 scopus 로고    scopus 로고
    • GnRH and GnRH receptor genes in the human genome
    • Neill JD. GnRH and GnRH receptor genes in the human genome. Endocrinology 2002; 143: 737-743.
    • (2002) Endocrinology , vol.143 , pp. 737-743
    • Neill, J.D.1
  • 21
    • 0037320294 scopus 로고    scopus 로고
    • A transcriptionally active human type II gonadotropin-releasing hormone receptor gene homolog overlaps two genes in the antisense orientation on chromosome 1q 12
    • Morgan K, Conklin D, Pawson AJ, Sellar R, Ott TR, Millar RP. A transcriptionally active human type II gonadotropin-releasing hormone receptor gene homolog overlaps two genes in the antisense orientation on chromosome 1q 12. Endocrinology 2003; 144: 423-436.
    • (2003) Endocrinology , vol.144 , pp. 423-436
    • Morgan, K.1    Conklin, D.2    Pawson, A.J.3    Sellar, R.4    Ott, T.R.5    Millar, R.P.6
  • 22
    • 0141460511 scopus 로고    scopus 로고
    • Evidence that gonadotropin-releasing hormone (GnRH) II stimulates luteinizing hormone and follicle-stimulating hormone secretion from monkey pituitary cultures by activating the GnRH I receptor
    • Okada Y, Murota-Kawano A, Kakar SS, Winters SJ. Evidence that gonadotropin-releasing hormone (GnRH) II stimulates luteinizing hormone and follicle-stimulating hormone secretion from monkey pituitary cultures by activating the GnRH I receptor. Biol Reprod 2003; 69: 1356-1356.
    • (2003) Biol Reprod , vol.69 , pp. 1356-1356
    • Okada, Y.1    Murota-Kawano, A.2    Kakar, S.S.3    Winters, S.J.4
  • 23
    • 0347286637 scopus 로고    scopus 로고
    • Position of Pro and Ser near Glu7.32 in the extracellular loop 3 of mammalian and nonmammalian gonadotropin-releasing hormone (GnRH) receptors is a critical determinant for differential ligand selectivity for mammalian GnRH and chicken GnRH-II
    • Wang C, Yun O, Maiti K, Oh DY, Kim KK, Chae CH, Lee CJ, Seong JY, Kwon HB. Position of Pro and Ser near Glu7.32 in the extracellular loop 3 of mammalian and nonmammalian gonadotropin-releasing hormone (GnRH) receptors is a critical determinant for differential ligand selectivity for mammalian GnRH and chicken GnRH-II. Mol Endocrinol 2004; 18: 105-116.
    • (2004) Mol Endocrinol , vol.18 , pp. 105-116
    • Wang, C.1    Yun, O.2    Maiti, K.3    Oh, D.Y.4    Kim, K.K.5    Chae, C.H.6    Lee, C.J.7    Seong, J.Y.8    Kwon, H.B.9
  • 24
    • 0032496280 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone receptors with intracellular carboxyl-terminal tails undergo acute desensitization of total inositol phosphate production and exhibit accelerated internalization kinetics
    • Heding A, Vrecl M, Bogerd J, McGregor A, Sellar R, Taylor PL, Eidne KA. Gonadotropin-releasing hormone receptors with intracellular carboxyl-terminal tails undergo acute desensitization of total inositol phosphate production and exhibit accelerated internalization kinetics. J Biol Chem 1998; 273: 11472-11477.
    • (1998) J Biol Chem , vol.273 , pp. 11472-11477
    • Heding, A.1    Vrecl, M.2    Bogerd, J.3    McGregor, A.4    Sellar, R.5    Taylor, P.L.6    Eidne, K.A.7
  • 25
    • 0033570130 scopus 로고    scopus 로고
    • Lack of a c-terminal tail in the mammalian gonadotropin-releasing hormone receptor confers resistance to agonist-dependent phosphorylation and rapid desensitization
    • Willars GB, Heding A, Vrecl M, Sellar R, Blomenröhr M, Nahorski SR, Eidne KA. Lack of a c-terminal tail in the mammalian gonadotropin-releasing hormone receptor confers resistance to agonist-dependent phosphorylation and rapid desensitization. J Biol Chem 1999; 274: 30146-30153.
    • (1999) J Biol Chem , vol.274 , pp. 30146-30153
    • Willars, G.B.1    Heding, A.2    Vrecl, M.3    Sellar, R.4    Blomenröhr, M.5    Nahorski, S.R.6    Eidne, K.A.7
  • 26
    • 0142029492 scopus 로고    scopus 로고
    • Differential G protein coupling preference of mammalian and nonmammalian gonadotropin-releasing hormone receptors
    • Oh DY, Wang L, Ahn RS, Park JY, Seong JY, Kwon HB. Differential G protein coupling preference of mammalian and nonmammalian gonadotropin-releasing hormone receptors. Mol Cell Endocrinol 2003; 205: 89-98.
    • (2003) Mol Cell Endocrinol , vol.205 , pp. 89-98
    • Oh, D.Y.1    Wang, L.2    Ahn, R.S.3    Park, J.Y.4    Seong, J.Y.5    Kwon, H.B.6
  • 27
    • 14844321940 scopus 로고    scopus 로고
    • Membrane-proximal region of the carboxyl terminus of the gonadotropin-releasing hormone receptor (GnRHR) confers differential signal transduction between mammalian and nonmammalian GnRHRs
    • Oh DY, Song JA, Moon JS, Moon MJ, Kim JI, Kim K, Kwon HB, Seong JY. Membrane-proximal region of the carboxyl terminus of the gonadotropin-releasing hormone receptor (GnRHR) confers differential signal transduction between mammalian and nonmammalian GnRHRs. Mol Endocrinol 2005; 19: 722-731.
    • (2005) Mol Endocrinol , vol.19 , pp. 722-731
    • Oh, D.Y.1    Song, J.A.2    Moon, J.S.3    Moon, M.J.4    Kim, J.I.5    Kim, K.6    Kwon, H.B.7    Seong, J.Y.8
  • 29
    • 0037206272 scopus 로고    scopus 로고
    • Differential desensitization and internalization of three different bullfrog gonadotropin-releasing hormone receptors
    • Acharjee S, Maiti K, Soh JM, Im WB, Seong JY, Kwon HB. Differential desensitization and internalization of three different bullfrog gonadotropin-releasing hormone receptors. Mol Cells 2002; 14: 101-107.
    • (2002) Mol Cells , vol.14 , pp. 101-107
    • Acharjee, S.1    Maiti, K.2    Soh, J.M.3    Im, W.B.4    Seong, J.Y.5    Kwon, H.B.6
  • 30
    • 0031757743 scopus 로고    scopus 로고
    • Agonist-induced endocytosis and recycling of the gonadotropin-releasing hormone receptor: Effect of β-arrestin on internalization kinetics
    • Vrecl M, Anderson L, Hanyaloglu A, McGregor AM, Groarke AD, Milligan G, Taylor PL, Eidne KA. Agonist-induced endocytosis and recycling of the gonadotropin-releasing hormone receptor: Effect of β-arrestin on internalization kinetics. Mol Endocrinol 1998; 12: 1818-1829.
    • (1998) Mol Endocrinol , vol.12 , pp. 1818-1829
    • Vrecl, M.1    Anderson, L.2    Hanyaloglu, A.3    McGregor, A.M.4    Groarke, A.D.5    Milligan, G.6    Taylor, P.L.7    Eidne, K.A.8
  • 31
    • 0032230140 scopus 로고    scopus 로고
    • Addition of catfish gonadotropin-releasing hormone (GnRH) receptor intracellular carboxyl-terminal tail to rat GnRH receptor alters receptor expression and regulation
    • Lin X, Janovick JA, Brothers S, Blomenröhr M, Bogerd J, Conn PM. Addition of catfish gonadotropin-releasing hormone (GnRH) receptor intracellular carboxyl-terminal tail to rat GnRH receptor alters receptor expression and regulation. Mol Endocrinol 1998; 12: 161-171.
    • (1998) Mol Endocrinol , vol.12 , pp. 161-171
    • Lin, X.1    Janovick, J.A.2    Brothers, S.3    Blomenröhr, M.4    Bogerd, J.5    Conn, P.M.6
  • 32
    • 0003045249 scopus 로고    scopus 로고
    • Visualization of unoccupied and occupied gonadotropin-releasing hormone receptors in living cells
    • Lin X, Cornea A, Janovick JA, Conn PM. Visualization of unoccupied and occupied gonadotropin-releasing hormone receptors in living cells. Mol Cell Endocrinol 1998; 146: 27-37.
    • (1998) Mol Cell Endocrinol , vol.146 , pp. 27-37
    • Lin, X.1    Cornea, A.2    Janovick, J.A.3    Conn, P.M.4
  • 33
    • 0034463035 scopus 로고    scopus 로고
    • The rat gonadotropin-releasing hormone receptor internalizes via a beta-arrestin-independent, but dynamin-dependent, pathway: Addition of a carboxyl-terminal tail confers beta-arrestin dependency
    • Heding A, Vrecl M, Hanyaloglu AC, Sellar R, Taylor PL, Eidne KA. The rat gonadotropin-releasing hormone receptor internalizes via a beta-arrestin-independent, but dynamin-dependent, pathway: Addition of a carboxyl-terminal tail confers beta-arrestin dependency. Endocrinology 2000; 141: 299-306.
    • (2000) Endocrinology , vol.141 , pp. 299-306
    • Heding, A.1    Vrecl, M.2    Hanyaloglu, A.C.3    Sellar, R.4    Taylor, P.L.5    Eidne, K.A.6
  • 35
    • 0034646687 scopus 로고    scopus 로고
    • β-Arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of β-arrestin1-dependent targeting of c-SRC in receptor endocytosis
    • Miller WE, Maudsley S, Ahn S, Khan KD, Luttrell LM, Lefkowitz RJ. β-Arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of β-arrestin1-dependent targeting of c-SRC in receptor endocytosis. J Biol Chem 2000; 275: 11312-11319.
    • (2000) J Biol Chem , vol.275 , pp. 11312-11319
    • Miller, W.E.1    Maudsley, S.2    Ahn, S.3    Khan, K.D.4    Luttrell, L.M.5    Lefkowitz, R.J.6
  • 36
    • 0034652310 scopus 로고    scopus 로고
    • Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors
    • Pierce KL, Maudsley S, Daaka Y, Luttrell LM, Lefkowitz RJ. Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors. Proc Natl Acad Sci USA 2000; 97: 1489-1494.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1489-1494
    • Pierce, K.L.1    Maudsley, S.2    Daaka, Y.3    Luttrell, L.M.4    Lefkowitz, R.J.5
  • 37
    • 0023125942 scopus 로고
    • Novel aspects of gonadotropin-releasing hormone action on inositol polyphosphate metabolism in cultured pituitary gonadotrophs
    • Morgan RO, Chang JP, Catt KJ. Novel aspects of gonadotropin-releasing hormone action on inositol polyphosphate metabolism in cultured pituitary gonadotrophs. J Biol Chem 1987; 262: 1166-1171.
    • (1987) J Biol Chem , vol.262 , pp. 1166-1171
    • Morgan, R.O.1    Chang, J.P.2    Catt, K.J.3
  • 38
    • 0024367312 scopus 로고
    • Identification of a specific site required for rapid heterologous desensitization of the beta-adrenergic receptor by cAMP-dependent protein kinase
    • Clark RB, Friedman J, Dixon RA, Strader CD. Identification of a specific site required for rapid heterologous desensitization of the beta-adrenergic receptor by cAMP-dependent protein kinase. Mol Pharmacol 1989; 36: 343-348.
    • (1989) Mol Pharmacol , vol.36 , pp. 343-348
    • Clark, R.B.1    Friedman, J.2    Dixon, R.A.3    Strader, C.D.4
  • 39
    • 0034006037 scopus 로고    scopus 로고
    • Identification of threonine residues controlling the agonist-dependent phosphorylation and desensitization of the rat A(3) adenosine receptor
    • Palmer TM, Stiles GL. Identification of threonine residues controlling the agonist-dependent phosphorylation and desensitization of the rat A(3) adenosine receptor. Mol Pharmacol 2000; 57: 539-545.
    • (2000) Mol Pharmacol , vol.57 , pp. 539-545
    • Palmer, T.M.1    Stiles, G.L.2
  • 40
    • 0037099297 scopus 로고    scopus 로고
    • Identification of two C-terminal amino acids, Ser(355) and Thr(357), required for short-term homologous desensitization of mu-opioid receptors
    • Wang HL, Chang WT, Hsu CY, Huang PC, Chow YW, Li AH. Identification of two C-terminal amino acids, Ser(355) and Thr(357), required for short-term homologous desensitization of mu-opioid receptors. Biochem Pharmacol 2002; 64: 257-266.
    • (2002) Biochem Pharmacol , vol.64 , pp. 257-266
    • Wang, H.L.1    Chang, W.T.2    Hsu, C.Y.3    Huang, P.C.4    Chow, Y.W.5    Li, A.H.6
  • 41
    • 0028242680 scopus 로고
    • Absence of rapid desensitization of the mouse gonadotropin-releasing hormone receptor
    • Davidson JS, Wakefield IK, Millar RP. Absence of rapid desensitization of the mouse gonadotropin-releasing hormone receptor. Biochem J 1994; 300: 299-302.
    • (1994) Biochem J , vol.300 , pp. 299-302
    • Davidson, J.S.1    Wakefield, I.K.2    Millar, R.P.3
  • 42
    • 0031734588 scopus 로고    scopus 로고
    • Potential regulatory roles for G protein-coupled receptor kinases and beta-arrestins in gonadotropin-releasing hormone receptor signaling
    • Neill JD, Duck LW, Musgrove LC, Sellers JC. Potential regulatory roles for G protein-coupled receptor kinases and beta-arrestins in gonadotropin-releasing hormone receptor signaling. Endocrinology 1998; 139: 1781-1788.
    • (1998) Endocrinology , vol.139 , pp. 1781-1788
    • Neill, J.D.1    Duck, L.W.2    Musgrove, L.C.3    Sellers, J.C.4
  • 43
    • 0035947557 scopus 로고    scopus 로고
    • Casein kinase II sites in the intracellular C-terminal domain of the thyrotropin-releasing hormone receptor and chimeric gonadotropin-releasing hormone receptors contribute to beta-arrestin-dependent internalization
    • Hanyaloglu AC, Vrecl M, Kroeger KM, Miles LE, Qian H, Thomas WG, Eidne KA. Casein kinase II sites in the intracellular C-terminal domain of the thyrotropin-releasing hormone receptor and chimeric gonadotropin-releasing hormone receptors contribute to beta-arrestin-dependent internalization. J Biol Chem 2001; 276: 18066-18074.
    • (2001) J Biol Chem , vol.276 , pp. 18066-18074
    • Hanyaloglu, A.C.1    Vrecl, M.2    Kroeger, K.M.3    Miles, L.E.4    Qian, H.5    Thomas, W.G.6    Eidne, K.A.7
  • 44
    • 0033304626 scopus 로고    scopus 로고
    • Simultaneous and independent visualization of the gonadotropin-releasing hormone receptor and its ligand: Evidence for independent processing and recycling in living cells
    • Cornea A, Janovick JA, Lin X, Conn PM. Simultaneous and independent visualization of the gonadotropin-releasing hormone receptor and its ligand: Evidence for independent processing and recycling in living cells. Endocrinology 1999; 140: 4272-4280.
    • (1999) Endocrinology , vol.140 , pp. 4272-4280
    • Cornea, A.1    Janovick, J.A.2    Lin, X.3    Conn, P.M.4
  • 45
    • 0034747357 scopus 로고    scopus 로고
    • Role of aspartate 7.32 (302) of the human gonadotropin-releasing hormone receptor in stabilizing a high-affinity ligand conformation
    • Fromme BJ, Katz AA, Roeske RW, Millar RP, Flanagan CA. Role of aspartate 7.32 (302) of the human gonadotropin-releasing hormone receptor in stabilizing a high-affinity ligand conformation. Mol Pharmacol 2001; 60: 1280-1287.
    • (2001) Mol Pharmacol , vol.60 , pp. 1280-1287
    • Fromme, B.J.1    Katz, A.A.2    Roeske, R.W.3    Millar, R.P.4    Flanagan, C.A.5
  • 46
    • 0036471926 scopus 로고    scopus 로고
    • Chimaeric gonadotropin-releasing hormone (GnRH) peptides with improved affinity for the catfish (Clarias gariepinus) GnRH receptor
    • Blomenröhr M, ter Laak T, Kuhne R, Beyermann M, Hund E, Bogerd J, Leurs R. Chimaeric gonadotropin-releasing hormone (GnRH) peptides with improved affinity for the catfish (Clarias gariepinus) GnRH receptor. Biochem J 2002; 361: 515-523.
    • (2002) Biochem J , vol.361 , pp. 515-523
    • Blomenröhr, M.1    ter Laak, T.2    Kuhne, R.3    Beyermann, M.4    Hund, E.5    Bogerd, J.6    Leurs, R.7
  • 47
    • 0141613856 scopus 로고    scopus 로고
    • Type II gonadotrophin-releasing hormone (GnRH-II) in reproductive biology
    • Pawson AJ, Morgan K, Maudsley SR, Millar RP. Type II gonadotrophin-releasing hormone (GnRH-II) in reproductive biology. Reproduction 2003; 126: 271-278.
    • (2003) Reproduction , vol.126 , pp. 271-278
    • Pawson, A.J.1    Morgan, K.2    Maudsley, S.R.3    Millar, R.P.4
  • 48
    • 23844444851 scopus 로고    scopus 로고
    • Molecular polymorphism of native gonadotropin-releasing hormone (GnRH) is restricted to mammalian GnRH and [hydroxyproline9]GnRH in the developing rat brain
    • Gautron JP, Gras C, Enjalbert A. Molecular polymorphism of native gonadotropin-releasing hormone (GnRH) is restricted to mammalian GnRH and [hydroxyproline9]GnRH in the developing rat brain. Neuroendocrinology 2005; 81: 69-86.
    • (2005) Neuroendocrinology , vol.81 , pp. 69-86
    • Gautron, J.P.1    Gras, C.2    Enjalbert, A.3
  • 49
    • 0037320294 scopus 로고    scopus 로고
    • A transcriptionally active human type II gonadotropin-releasing hormone receptor gene homolog overlaps two genes in the antisense orientation on chromosome 1q.12
    • Morgan K, Conklin D, Pawson AJ, Sellar R, Ott TR, Millar RP. A transcriptionally active human type II gonadotropin-releasing hormone receptor gene homolog overlaps two genes in the antisense orientation on chromosome 1q.12. Endocrinology 2003; 144: 423-436.
    • (2003) Endocrinology , vol.144 , pp. 423-436
    • Morgan, K.1    Conklin, D.2    Pawson, A.J.3    Sellar, R.4    Ott, T.R.5    Millar, R.P.6
  • 50
    • 4544262511 scopus 로고    scopus 로고
    • Newly recognized GnRH receptors: Function and relative role
    • Neill JD, Musgrove LC, Duck LW. Newly recognized GnRH receptors: function and relative role. Trends Endocrinol Metab 2004; 15: 383-392.
    • (2004) Trends Endocrinol Metab , vol.15 , pp. 383-392
    • Neill, J.D.1    Musgrove, L.C.2    Duck, L.W.3
  • 51
    • 0038030829 scopus 로고    scopus 로고
    • Relative effect of gonadotropin-releasing hormone (GnRH)-I and GnRH-II on gonadotropin release
    • Densmore VS, Urbanski HF. Relative effect of gonadotropin-releasing hormone (GnRH)-I and GnRH-II on gonadotropin release. J Clin Endocrinol Metab 2003; 88: 2126-2134.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2126-2134
    • Densmore, V.S.1    Urbanski, H.F.2
  • 52
    • 0035114414 scopus 로고    scopus 로고
    • Differential regulation of two forms of gonadotropin-releasing hormone messenger ribonucleic acid in human granulosa-luteal cells
    • Kang SK, Tai CJ, Nathwani PS, Leung PC. Differential regulation of two forms of gonadotropin-releasing hormone messenger ribonucleic acid in human granulosa-luteal cells. Endocrinology 2001; 142: 182-192.
    • (2001) Endocrinology , vol.142 , pp. 182-192
    • Kang, S.K.1    Tai, C.J.2    Nathwani, P.S.3    Leung, P.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.