Molecular polymorphism of native gonadotropin-releasing hormone (GnRH) is restricted to mammalian GnRH and [hydroxyproline9] GnRH in the developing rat brain

Neuroendocrinology

Volumn 81, Issue 2, 2005, Pages 69-86

  Gautron, Jean Pierre ^a   Gras, Christophe ^a   Enjalbert, Alain ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

Author keywords

GnRH and development; Gonadotropin releasing hormone; Posttranslational processing

Indexed keywords

BRAIN EXTRACT; GLYCINE; GONADORELIN DERIVATIVE; GONADORELIN[1-5]; HYDROXYPROLINE; PEPTIDE; PROTEIN PRECURSOR; UNCLASSIFIED DRUG; GONADORELIN;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CATABOLISM; CHICKEN; CHROMATOGRAPHY; COMPARATIVE STUDY; CONTROLLED STUDY; ELUTION; FEMALE; GENETIC POLYMORPHISM; HORMONE DETERMINATION; HYDROXYLATION; HYPOTHALAMUS; IMMUNOREACTIVITY; MALE; NEWBORN; NONHUMAN; ONTOGENY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROCESSING; RAT; SEX DIFFERENCE; TIME SERIES ANALYSIS; AGE; ANIMAL; BRAIN; BRAIN LEVEL; CHEMISTRY; CLASSIFICATION; CROSS REACTION; FROGS AND TOADS; GROWTH, DEVELOPMENT AND AGING; HISTOLOGY; LIQUID CHROMATOGRAPHY; METABOLISM; METHODOLOGY; PHYSIOLOGY; PREGNANCY; RADIOIMMUNOASSAY; SPECIES DIFFERENCE; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; ANURA; BRAIN; BRAIN CHEMISTRY; CHROMATOGRAPHY, LIQUID; CROSS REACTIONS; FEMALE; GONADOTROPIN-RELEASING HORMONE; HYDROXYPROLINE; HYPOTHALAMUS; MALE; PREGNANCY; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; SEX FACTORS; SPECIES SPECIFICITY; TISSUE DISTRIBUTION;

EID: 23844444851     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000084896     Document Type: Article

References (51)

1. Matsuo H, Baba Y, Nair RMG, Arimura A, Schally AV: Structure of the porcine LH- and FSH-releasing hormone. I. The proposed amino acid sequence. Biochem Biophys Res Commun 1971;43:1334-1339.
2. Burgus R, Butcher M, Amoss M, Ling N, Monahan M, Rivier J, Fellows R, Blackwell R, Vale W, Guillemin R: Primary structure of the ovine hypothalamic luteinizing hormone releasing factor. Proc Natl Acad Sci USA 1972;69:278-282.
3. 9]luteinizing hormone-releasing hormone: A novel peptide in mammalian and frog hypothalamus. Neurochem Int 1991;18:221-223.
4. Dellovade TL, King JA, Millar RP, Rissman EF: Presence and differential distribution of distinct forms of immunoreactive gonadotropin-releasing hormone in the musk shrew brain. Neuroendocrinology 1993;58:166-167.
5. Chen A, Yahalom D, Ben-Aroya N, Kaganovsky E, Okon E, Koch Y: A second isoform of gonadotropin-releasing hormone is present in the brain of human and rodents. FEBS Lett 1998;435:199-203.
6. Montaner AD, Mongiat L, Lux-Lantos VA, Warby C, Chewpoy B, Bianchi MS, Libertun C, Rivier JE, Sherwood NM, Somoza G: Guinea pig gonadotropin-releasing hormone: Expression pattern, characterization and biological activity. Neuroendocrinology 2002;75:326-338.
7. Yahalom D, Chen A, Ben-Aroya N, Rahimipour S, Kaganovsky E, Okon E, Fridkin M, Koch Y: The gonadotropin-releasing hormone family of neuropeptides in the brain of human, bovine and rat: Identification of a third isoform. FEBS Lett 1999;463:289-294.
8. Hiney JK, Sower SA, Yu WH, McCann SM, Dees WL: Gonadotropin-releasing hormone neurons in the preoptic-hypothalamic region of the rat contain lamprey gonadotropin-releasing hormone III, mammalian luteinizing hormone-releasing hormone, or both peptides. Proc Natl Acad Sci USA 2002;99:2386-2391.
9. King JA, Hassan MF, Mehl AE, Millar RP: Gonadotropin-releasing hormone molecular forms in mammalian hypothalamus. Endocrinology 1988;122:2742-2752.
10. Kelsall R, Coe IR, Sherwood NM: Phylogeny and ontogeny of gonadotropin-releasing hormone: Comparison of guinea pig, rat and a protochordate. Gen Comp Endocrinol 1990;78:479-494.
11. Lescheid DW, Terasawa EI, Abler LA, Urbanski HF, Warby CM, Millar RP, Sherwood NM: A second form of gonadotropin-releasing hormone (GnRH) with characteristics of chicken GnRH-II is present in the primate brain. Endocrinology 1997;138:5618-5629.
12. Montaner AD, Mongiat L, Lux-Lantos VA, Park MK, Fischer WH, Craig AG, Rivier JE, Lescheid D, Lovejoy D, Libertun C, Sherwood NM, Somoza GM: Structure and biological activity of gonadotropin-releasing hormone isoforms isolated from rat and hamster brains. Neuroendocrinology 2001;74:202-212.
13. Montaner AD, Somoza G, King JA, Bianchini JJ, Bolis CG, Affanni JM: Chromatographic and immunological identification of GnRH (gonadotropin-releasing hormone) variants. Occurrence of mammalian and a salmon-like GnRH in the forebrain of an eutherian mammal: Hydrochaeris hydrochaeris (Mammalia, Rodentia). Regul Pept 1998;73:197-204.
14. Montaner AD, Affanni JM, King JA, Bianchini, JJ, Tonarelli G, Somoza G: Differential distribution of gonadotropin-releasing hormone variants in the brain of Hydrochaeris hydrochaeris (Mammalia, Rodentia). Cell Mol Neurobiol 1999;19:635-651.
15. 9]LHRH are present in the rat hypothalamus. Biochem Biophys Res Commun 1992;189:1368-1373.
16. 9]LHRH in the rat hippocampus and olfactory bulb. Neuroendocrinology 1993;58:240-250.
17. Lew RA, Tetaz TJ, Glucksman MJ, Roberts JL, Smith AI: Evidence for a two-step mechanism of gonadotropin-releasing hormone metabolism by prolyl endopeptidase and metalloendopeptidase EC 3.4.24.15 in ovine hypothalamic extracts. J Biol Chem 1994;269:12626-12632.
18. 9]LHRH. CR Acad Sci (Paris) 1992;314:355-359.
19. Di Fiore MM, King JA, D'Aniello B, Rastogi RK: Immunoreactive mammalian and chicken-II GnRHs in Rana esculenta brain during development. Regul Pept 1996;62:119-124.
20. Gopinath A, Tseng A, Whitlock K: Temporal and spatial expression of gonadotropin-releasing hormone in the brain of developing zebrafish (Danio rerio). Gene Exp Patterns 2004;4:65-70.
21. Von Schalburg KR, Warby CM, Sherwood NM: Evidence for gonadotropin-releasing hormone peptides in the ovary and testis of rainbow trout. Biol Reprod 1999;60:1338-1344.
22. Nett TM, Akbar AM, Niswender GD, Heidun GD, White WF: A radioimmunoassay for gonadotropin-releasing hormone in serum. J Clin Endocrinol Metab 1973;36:880-885.
23. Siler-Khodr TM, Grayson M: Action of chicken II GnRH on the human placenta. J Clin Endocrinol Metab 2001;86:804-810.
24. Dees WL, Hiney JK, Sower SA, Yu WH, McCann SM: Localization of immunoreactive lamprey gonadotropin-releasing hormone in the rat brain. Peptides 1999;20:1503-1511.
25. Dubois EA, Zandbergen MA, Peute J, Goos HJ: Evolutionary development of three gonadotropin-releasing hormone systems in vertebrates. Brain Res Bull 2002;57:413-418.
26. Grove-Strawser D, Sower SA, Ronsheim PM, Connolly JB, Bourn CG, Rubin BS: Guinea pig GnRH: Localization and physiological activity reveal that it, not mammalian GnRH, is the major neuroendocrine form in guinea pigs. Endocrinology 2002;143:1602-1612.
27. Pawson AJ, Morgan K, Maudsley SR, Millar RP: Type II gonadotrophin- releasing hormone (GnRH-II) in reproductive biology. Reproduction 2003;126:271-278.
28. Gault PM, Morgan PM, Pawson AJ, Millar RP, Lincoln GA: Sheep exhibit novel variations in the organization of the mammalian type II gonadotropin-releasing hormone receptor gene. Endocrinology 2004;145:2362-2374.
29. Gestrin ED, White RB, Fernald RD: Second form of gonadotropin-releasing hormone in mouse: Immunocytochemistry reveals hippocampal and periventricular distribution. FEBS Lett 1999;448:289-291.
30. Chen A, Yahalom D, Laskar-Levy O, Rahimipour S, Ben-Aroya N, Koch Y: Two isoforms of gonadotropin-releasing hormone are coexpressed in neuronal cell lines. Endocrinology 2001;142:830-837.
31. Stopa EG, Sower SA, Svendsen CN, King JC: Polygenic expression of gonadotropin-releasing hormone in human? Peptides 1988;9:419-423.
32. Sower SA, Chiang YC, Lovas S, Conlon JM: Primary structure and biological activity of a third gonadotropin-releasing hormone from lamprey brain. Endocrinology 1993;132:1125-1131.
33. Jimenez-Linan M, Rubin BS, King JC: Examination of guinea pig luteinizing hormone-releasing hormone gene reveals a unique decapeptide and existence of two transcripts in the brain. Endocrinology 1997;138:4123-4130.
34. 9]GnRH from the rat hypothalamus during postnatal development. J Neuroendocrinol 2000;12:919-926.
35. Wetsel WC, Mellon PL, Weiner RI, Negro-Vilar A: Metabolism of pro-luteinizing hormone-releasing hormone in immortalized hypothalamic neurons. Endocrinology 1991;129:1584-1595.
36. 9]luteinizing hormone-releasing hormone and its smallest precursor forms in immortalized luteinizing hormone-releasing hormone-secreting neurons (GT1-7), and evaluation of their mode of action on pituitary cells. Mol Cell Endocrinol 1995;110:161-173.
37. 9]-GnRH from the rat hypothalamus exhibits a differential sensitivity to castration and second messengers. Neuroendocrinology 1998;68:281-292.
38. Chiappa SA, Fink G: Releasing factor and hormonal changes in the hypothalamic-pituitary-gonadotrophin and -adrenocorticotrophin systems before and after birth and puberty in male, female and androgenized female rats. J Endocrinol 1977;72:211-224.
39. Smith AI, Tetaz TJ, Roberts JL, Glucksman MJ, Clarke IJ, Lew RA: The role of EC 3.4.24.15 in the post-secretory regulation of peptide signals. Biochimie (Paris) 1994;76:288-294.
40. Pierotti AR, Lasdun A, Ayala JM, Roberts JL, Molineaux CJ: Endopeptidase-24.15 in rat hypothalamus/pituitary/gonadal axis. Mol Cell Endocrinol 1991;76:95-103.
41. Yamanaka C, Lebrethon MC, Vandersmissen E, Gerard A, Purnelle G, Lemaitre M, Wilk S, Bourguignon JP: Early prepubertal ontogeny of pulsatile gonadotropin-releasing hormone (GnRH) secretion. I. Inhibitory autofeedback control through prolyl endopeptidase degradation of GnRH. Endocrinology 1999;140:4609-4615.
42. Agirregoitia N, Irazusta A, Ruiz F, Irazusta J, Gil J: Ontogeny of soluble and particulate prolyl endopeptidase activity in several areas of the rat brain and in the pituitary gland. Dev Neurosci 2003;25:316-323.
43. Griffiths EC, Hooper KC, Jeffcoate SL, Holland DT: The effect of gonadectomy and gonadal steroids on the activity of hypothalamic peptidases inactivating luteinizing hormone-releasing hormone. Brain Res 1975;88:384-388.
44. Advis JP, Krause JE, McKelvy JF: Evidence that endopeptidase-catalyzed luteinizing hormone-releasing hormone cleavage contributes to the regulation of median eminence LHRH levels during positive steroid feedback. Endocrinology 1984;112:1147-1149.
45. O'Conner JL, Lapp CA, Mahesh VB: Peptidase activity in the hypothalamus and pituitary of the rat: Fluctuations and possible regulatory role of luteinizing hormone releasing hormone-degrading activity during the estrus cycle. Biol Reprod 1984;30:855-862.
46. Griffiths EC, Hooper KC, Jeffcoate SL, Holland DT: Effect of neonatal androgen on the activity of peptidases in the rat brain inactivating luteinizing hormone-releasing hormone. Horm Res 1976;7:218-226.
47. Pang SF, Caggiula AR, Gay VL, Goodman RL, Pang CS: Serum concentration of testosterone, oestrogens, luteinizing hormone and follicle-stimulating hormone in male and female rats during the critical period of neural sexual differentiation. J Endocrinol 1979;80:103-110.
48. Germain BJ, Campbell PS, Anderson JN: Role of the serum estrogen-binding protein in the control of tissue estradiol levels during postnatal development of the female rat. Endocrinology 1978;103:1401-1410.
49. Wu TJ, Gibson MJ, Silverman AJ: Gonadotropin-releasing hormone neurons of the developing tectum of the mouse. J Neuroendocrinol 1995;7:899-902.
50. Quanbeck C, Sherwood NM, Millar RP, Terasawa EI: Two populations of luteinizing hormone-releasing hormone neurons in the forebrain of the rhesus macaque during embryonic development. J Comp Neurol 1997;380:293-309.
51. Glucksman MJ, Roberts JL: Presence of luteinizing hormone-releasing hormone fragments in the rhesus monkey forebrain. J Comp Neurol 2001;439:491-504.