Synthesis, discovery and mechanism of 2,6-dimethoxy-N-(4-methoxyphenyl)benzamide as potent depigmenting agent in the skin

Biochemical and Biophysical Research Communications

Volumn 349, Issue 1, 2006, Pages 39-49

  Choi, Sang Yoon ^a   Hwang, Jae Sung ^b   Kim, Sanghee ^c   Kim, Sun Yeou ^d  

^a Korea Food Research Institute   (South Korea)

^b Skin Research Institute   (South Korea)

^c Seoul National University   (South Korea)

^d Kyung Hee University   (South Korea)

Author keywords

Biaryl amide; Depigment agent; Dopachrome tautomerase; Melanin; Skin

Indexed keywords

2,6 DIMETHOXY N (4 METHOXYPHENYL)BENZAMIDE; 5,6 DIHYDROXYINDOLE 2 CARBOXYLIC ACID; ANILINE; BENZAMIDE DERIVATIVE; BENZOIC ACID; DEPIGMENTING AGENT; DOPACHROME TAUTOMERASE; MELAN A; MELANIN; MONOPHENOL MONOOXYGENASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL TRANSFORMATION; CELL VIABILITY; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVATION; GUINEA PIG; HYPERPIGMENTATION; MELANOGENESIS; NONHUMAN; PRIORITY JOURNAL; SKIN COLOR; SKIN PIGMENTATION; SYNTHESIS; ULTRAVIOLET B RADIATION;

ANILINE COMPOUNDS; ANIMALS; ANISOLES; BENZAMIDES; BENZOIC ACID; CELL LINE, TUMOR; ENZYME ACTIVATION; GUINEA PIGS; HUMANS; INDOLES; INTRAMOLECULAR OXIDOREDUCTASES; MODELS, CHEMICAL; MONOPHENOL MONOOXYGENASE; SKIN;

CAVIA PORCELLUS;

EID: 33748447149     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.07.206     Document Type: Article

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