Higher serum nitrate levels are associated with poor survival in lung cancer patients

Clinical Biochemistry

Volumn 39, Issue 9, 2006, Pages 898-903

  Colakogullari, Mukaddes ^a   Ulukaya, Engin ^a   Yilmaztepe, Arzu ^a   Ocakoglu, Gokhan ^a   Yilmaz, Meryem ^a   Karadag, Mehmet ^a   Tokullugil, Asuman ^a  

^a ULUDAG UNIVERSITY   (Turkey)

Author keywords

Lung cancer; Nitric oxide (NO); Serum nitrite nitrate; Survival; Vascular endothelial growth factor A (VEGF A)

Indexed keywords

ANGIOGENIC FACTOR; CISPLATIN; NITRATE; NITRIC OXIDE; NITRITE; VASCULOTROPIN A;

ADULT; ANGIOGENESIS; ARTICLE; BLOOD LEVEL; CALCULATION; CANCER COMBINATION CHEMOTHERAPY; CANCER SURVIVAL; CHEMICAL REACTION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; GRIESS REACTION; HUMAN; KAPLAN MEIER METHOD; LOG RANK TEST; LUNG CANCER; MALE; METASTASIS; OVERALL SURVIVAL; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; REACTION ANALYSIS; SURVIVAL RATE; TURKEY (REPUBLIC);

AGED; CARCINOMA; CASE-CONTROL STUDIES; DRUG THERAPY; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; NITRATES; NITRITES; SURVIVAL RATE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33748437046     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2006.06.008     Document Type: Article

References (38)

1. Kuroi K., and Toi M. Circulating angiogenesis regulators in cancer patients. Int. J. Biol. Markers 16 1 (2001) 5-26
2. Poon R.T., Ng I.O., Lau C., Yu W.C., Fan S.T., and Wong J. Correlation of serum basic fibroblast growth factor levels with clinicopathologic features and postoperative recurrence in hepatocellular carcinoma. Am. J. Surg. 182 3 (2001) 298-304
3. Sandler A.B. Targeting angiogenesis in lung cancer. Semin. Oncol. 32 6 Suppl. 10 (2005) S16-S22
4. Dudek A.Z., and Mahaseth H. Circulating angiogenic cytokines in patients with advanced non-small cell lung cancer: correlation with treatment response and survival. Cancer Invest. 23 3 (2005) 193-200
5. Jenkins D.C., Charles I.G., Thomsen L.L., et al. Roles of nitric oxide in tumour growth. Proc. Natl. Acad. Sci. U. S. A. 92 10 (1995) 4392-4396
6. Wink D.A., Vodovotz Y., Laval J., Laval F., Dewhirst M.W., and Mitchell J.B. The multifaceted roles of nitric oxide in cancer. Carcinogenesis 19 5 (1998) 711-721
7. Jadeski L.C., Hum K.O., Chakraborty C., and Lala P.K. Nitric oxide promotes murine mammary tumour growth and metastasis by stimulating tumour cell migration, invasiveness and angiogenesis. Int. J. Cancer 86 1 (2000) 30-39
8. Fukumura D., Gohongi T., Kadambi A., et al. Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability. Proc. Natl. Acad. Sci. U. S. A. 98 5 (2001) 2604-2609
9. Jones M.K., Tsugawa K., Tarnawski A.S., and Baatar D. Dual actions of nitric oxide on angiogenesis: possible roles of PKC, ERK, and AP-1. Biochem. Biophys. Res. Commun. 318 2 (2004) 520-528
10. RayChaudhury A., Frischer H., and Malik A.B. Inhibition of endothelial cell proliferation and bFGF-induced phenotypic modulation by nitric oxide. J. Cell. Biochem. 63 2 (1996) 125-134
11. Edwards P., Cendan J.C., Topping D.B., Moldawer L.L., MacKay S., Copeland E.M.I.I.I., et al. Tumor cell nitric oxide inhibits cell growth in vitro, but stimulates tumorigenesis and experimental lung metastasis in vivo. J. Surg. Res. 63 1 (1996) 49-52
12. Fujimoto H., Sasaki J., Matsumoto M., Suga M., Ando Y., Iggo R., et al. Significant correlation of nitric oxide synthase activity and p53 gene mutation in stage I lung adenocarcinoma. Jpn. J. Cancer Res. 89 7 (1998) 696-702
13. Gauthier N., Lohm S., Touzery C., et al. Tumour-derived and host-derived nitric oxide differentially regulate breast carcinoma metastasis to the lungs. Carcinogenesis 25 9 (2004) 1559-1565
14. Kisley L.R., Barrett B.S., Bauer A.K., et al. Genetic ablation of inducible nitric oxide synthase decreases mouse lung tumorigenesis. Cancer Res. 62 23 (2002) 6850-6856
15. Kaynar H., Meral M., Turhan H., Keles M., Celik G., and Akcay F. Glutathione peroxidase, glutathione-S-transferase, catalase, xanthine oxidase, Cu-Zn superoxide dismutase activities, total glutathione, nitric oxide, and malondialdehyde levels in erythrocytes of patients with small cell and non-small cell lung cancer. Cancer Lett. 227 2 (2005) 133-139
16. Green L.C., Wagner D.A., Glogowski J., Skipper P.L., Wishnok J.S., and Tannenbaum S.R. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal. Biochem. 126 1 (1982) 131-138
17. Thomas K.A. Vascular endothelial growth factor, a potent and selective angiogenic agent. J. Biol. Chem. 271 2 (1996) 603-606
18. Ambs S., Bennett W.P., Merriam W.G., et al. Vascular endothelial growth factor and nitric oxide synthase expression in human lung cancer and the relation to p53. Br. J. Cancer 78 2 (1998) 233-239
19. Tsao M.S., Liu N., Nicklee T., Shepherd F., and Viallet J. Angiogenesis correlates with vascular endothelial growth factor expression but not with Ki-ras oncogene activation in non-small cell lung carcinoma. Clin. Cancer Res. 3 10 (1997) 1807-1814
20. Marrogi A.J., Travis W.D., Welsh J.A., Khan M.A., Rahim H., Tazelaar H., et al. Nitric oxide synthase, cyclooxygenase 2, and vascular endothelial growth factor in the angiogenesis of non-small cell lung carcinoma. Clin. Cancer Res. 6 12 (2000) 4739-4744
21. Choi J.H., Kim H.C., Lim H.Y., et al. Vascular endothelial growth factor in the serum of patients with non-small cell lung cancer: correlation with platelet and leukocyte counts. Lung Cancer 33 2-3 (2001) 171-179
22. Hood J.D., Meininger C.J., Ziche M., and Granger H.J. VEGF upregulates ecNOS message, protein, and NO production in human endothelial cells. Am. J. Physiol. 274 3 Pt 2 (1998) H1054-H1058
23. Jozkowicz A., Cooke J.P., Guevara I., Huk I., Funovics P., Pachinger O., et al. Genetic augmentation of nitric oxide synthase increases the vascular generation of VEGF. Cardiovasc. Res. 51 4 (2001) 773-783
24. Schmidt H.H., Warner T.D., Nakane M., Forstermann U., and Murad F. Regulation and subcellular location of nitrogen oxide synthases in RAW264.7 macrophages. Mol. Pharmacol. 41 4 (1992) 615-624
25. Moshage H., Kok B., Huizenga J.R., and Jansen P.L. Nitrite and nitrate determinations in plasma: a critical evaluation. Clin. Chem. 41 6 Pt 1 (1995) 892-896
26. Matsuyama W., Hashiguchi T., Mizoguchi A., Iwami F., Kawabata M., Arimura K., et al. Serum levels of vascular endothelial growth factor dependent on the stage progression of lung cancer. Chest 118 4 (2000) 948-951
27. Dudek A.Z., and Mahaseth H. Circulating angiogenic cytokines in patients with advanced non-small cell lung cancer: correlation with treatment response and survival. Cancer Invest. 23 3 (2005) 193-200
28. Kaya A., Ciledag A., Gulbay B.E., Poyraz B.M., Celik G., Sen E., et al. The prognostic significance of vascular endothelial growth factor levels in sera of non-small cell lung cancer patients. Respir. Med. 98 7 (2004) 632-636
29. Laack E., Kohler A., Kugler C., et al. Pretreatment serum levels of matrix metalloproteinase-9 and vascular endothelial growth factor in non-small-cell lung cancer. Ann. Oncol. 13 10 (2002) 1550-1557
30. Niklinska W., Burzykowski T., Chyczewski L., and Niklinski J. Expression of vascular endothelial growth factor (VEGF) in non-small cell lung cancer (NSCLC): association with p53 gene mutation and prognosis. Lung Cancer 34 Suppl. 2 (2001) S59-S64
31. Gibb R.K., Taylor D.D., Wan T., O'Connor D.M., Doering D.L., and Gercel-Taylor C. Apoptosis as a measure of chemosensitivity to cisplatin and taxol therapy in ovarian cancer cell lines. Gynecol. Oncol. 65 1 (1997) 13-22
32. Kaushal G.P., Kaushal V., Hong X., and Shah S.V. Role and regulation of activation of caspases in cisplatin-induced injury to renal tubular epithelial cells. Kidney Int. 60 5 (2001) 1726-1736
33. Herr I., Ucur E., Herzer K., et al. Glucocorticoid cotreatment induces apoptosis resistance toward cancer therapy in carcinomas. Cancer Res. 63 12 (2003) 3112-3120
34. Zhou J., Zhu Q., and Yao H. Chemotherapy of non-small-cell lung cancer (NSCLC) and changes in serum sAPO-1/Fas and nitric oxide (NO) levels. Zhonghua Zhongliu Zazhi 22 3 (2000 (May)) 225-227
35. Kimura H., and Esumi H. Reciprocal regulation between nitric oxide and vascular endothelial growth factor in angiogenesis. Acta Biochim. Pol. 50 1 (2003) 49-59
36. Puhakka A., Kinnula V., Napankangas U., et al. High expression of nitric oxide synthases is a favorable prognostic sign in non-small cell lung carcinoma. APMIS 111 12 (2003) 1137-1146
37. Saleh S., and El-Demerdash E. Protective effects of l-arginine against cisplatin-induced renal oxidative stress and toxicity: role of nitric oxide. Basic Clin. Pharmacol. Toxicol. 97 2 (2005) 91-97
38. Khattab M.M., Mostafa A., and Al-Shabanah O. Effects of captopril on cardiac and renal damage, and metabolic alterations in the nitric oxide-deficient hypertensive rat kidney. Blood Press Res. 28 4 (2005) 243-250