Inhibition of endothelial cell proliferation and bFGF-induced phenotypic modulation by nitric oxide

Journal of Cellular Biochemistry

Volumn 63, Issue 2, 1996, Pages 125-134

  RayChaudhury, Amlan ^a   Frischer, Henri ^a   Malik, Asrar B ^a,b  

^a RUSH MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF ILLINOIS   (United States)

Author keywords

angiogenesis; contact inhibition; inhibitor; SNAP

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CELL PROLIFERATION; DOSE RESPONSE; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME ACTIVATION; GROWTH INHIBITION; GROWTH REGULATION; MITOGENESIS; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

ANIMALIA;

EID: 0029903812     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-4644(19961101)63:2<125::aid-jcb1>3.0.co;2-#     Document Type: Article

References (30)

1. Blanco FJ, Ochs RL, Schwarz H, Lotz M (1995): Chondrocyte apoptosis induced by nitric oxide. Am J Pathol 146:75-85.
2. Cornwell TL, Arnold E, Boerth NJ, Lincoln TM (1994): Inhibition of smooth muscle cell growth by nitric oxide and activation of cAMP-dependent protein kinase by cGMP. Am J Physiol 267:C1405-1413.
3. Dawson VL, Dawson TM, Bartley DA, Uhl GR, Snyder SH (1993): Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. J Neurosci 13:2651-2661.
4. Del Vecchio PJ, Siflinger-Birnboim A, Belloni PA, Holleran LA, Lum H, Malik AB (1992): Culture and characterization of pulmonary microvascular endothelial cells. In Vitro Cell Dev Biol 28A:711-715.
5. Engerman RL, Pfaffenbach D, Davis MD (1967): Cell turn-over of capillaries. Lab Invest 17:738-743.
6. Folkman J, Shing Y (1992): Angiogenesis. J Biol Chem 267:10931-10934.
7. Fukuo K, Inoue T, Morimoto S, Nakahashi T, Yasuda O, Kitano S, Sasada R, Ogihara T (1995): Nitric oxide mediates cytotoxicity and basic fibroblast growth factor release in cultured vascular smooth muscle cells. A possible mechanism of neovascularization in atherosclerotic plaques. J Clin Invest 95:669-676.
8. Garg UC, Devi L, Turndorf H, Goldfrank LR, Bansinath M (1992): Effect of nitric oxide on mitogenesis and proliferation of cerebellar glial cells. Brain Res 592:208-212.
9. Good DJ, Polverini PJ, Rastinejad F, Le Beau MM, Lemons RS, Frazier WA, Bouck NP (1990): A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. PNAS 87:6624-6628.
10. Goureau O, Lepoivre M, Becquet F, Courtois Y (1993): Differential regulation of inducible nitric oxide synthase by fibroblast growth factors and transforming growth factor beta in bovine retinal pigmented epithelial cells: Inverse correlation with cellular proliferation. PNAS 90: 4276-4280.
11. Goureau O, Lepoivre M, Courtois Y (1992): Lipopolysaccharide and cytokines induce a macrophage-type nitric oxide synthase in bovine retinal pigmented epithelial cells. Biochem Biophys Res Commun 186:854-859.
12. Hobson B, Denekamp J (1984): Endothelial proliferation in tumours and normal tissues: Continuous labeling studies. Br J Cancer 49:405-413.
13. Hogan M, Cerami A, Bucala R (1992): Advanced glycosylation endproducts block the antiproliferative effect of nitric oxide. Role in the vascular and renal complications of diabetes mellitus. J Clin Invest 90:1110-1115.
14. Klagsbrun M, D'Amore PA (1991): Regulators of angiogenesis. Annu Rev Physiol 53:217-239.
15. Kroncke KD, Brenner HH, Rodriguez ML, Etzkorn K, Noack EA, Kolb H, Kolb-Bachofen V (1993): Pancreatic islet cells are highly susceptible towards the cytotoxic effects of chemically generated nitric oxide. Biochim Biophys Acta 1182:221-229.
16. Lindner V, Majack R, Reidy MA (1990): Basic FGF stimulates endothelial regrowth and proliferation in denuded arteries. Effect of bFGF on endothelial recovery following injury. J Clin Invest 85:2004-2008.
17. Malinski T, Bailey F, Zhang ZG, Chopp M (1993): Nitric oxide measured by porphyrinic microsensor in rat brain after transient middle cerebral artery occlusion. J Cereb Blood Flow Metab 13:355-358.
18. Maragos CM, Wang JM, Hrabie JA, Oppenheim JJ, Keefer LK (1993): Nitric oxide/nucleophile complexes inhibit the in vitro proliferation of A3 75 melanoma cells via nitric oxide release. Cancer Res 53:564-568.
19. Moncada S, Higgs A (1993): The L-arginine-nitric oxide pathway. New Eng J Med 329:2002-2012.
20. Murphy AN, Unsworth EJ, Stetler-Stevenson WG (1993): Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular cell proliferation. J Cell Physiol 157:351-358.
21. O'Reilly MS, Holmgren L, Shing Y, Chen C, Rosenthal RA, Moses M, Lane WS, Cao Y, Sage EH, Folkman J (1994): Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79:315-328.
22. Pellegata F, Radaelli A, Ferrero E, Toninelli E, Vidai MJ, Chierchia SL, Zocchi MR (1994): Inducible nitric oxide synthase modulates fibronectin production in the EA.hy926 cell line and cultured human umbilical vein endothelial cells. J Cardiovasc Pharmacol 24:1014-1019.
23. Pepper MS, Belin D, Montesano R, Orci L, Vassalli J-D (1990): Transforming growth factor-betal modulates basic fibroblast growth factor-induced proteolytic and angiogenic properties of endothelial cells in vitro. J Cell Biol 111:743-755.
24. Pipili-Synetos E, Sakkoula E, Haralabopoulos G, Andriopoulou P, Peristeris P, Maragoudakis ME (1994): Evidence that nitric oxide is an endogenous antiangiogenic mediator. Br J Pharmacol 111:892-900.
25. Saksela O, Moscatelli D, Rifkin DB (1987): The opposing effects of basic fibroblast growth factor and transforming growth factor beta on the regulation of plasminogen activator activity in capillary endothelial cells. J Cell Biol 105:957-963.
26. Sarkar R, Webb RC, Stanley JC (1995): Nitric oxide inhibition of endothelial cell mitogenesis and proliferation. Surgery 118:274-279.
27. Schultz-Hector S, Haghayegh S (1993): β-fibroblast growth factor expression in human and murine squamous cell carcinomas and its relationship to regional endothelial cell proliferation. Cancer Res 53:1444-1449.
28. Takahashi JA, Fukumoto M, Kozai Y, Ito N, Oda Y, Kikuchi H, Hatanaka M (1991): Inhibition of cell growth and tumorigenesis of human glioblastoma cells by a neutralizing antibody against human basic fibroblast growth factor. FEBS Lett 288:65-71.
29. Yang W, Ando J, Korenaga R, Toyo-oka T, Kamiya A (1994): Exogenous nitric oxide inhibits proliferation of cultured vascular endothelial cells. Biochem Biophys Res Commun 203:1160-1167.
30. Ziche M, Morbidelli L, Masini E, Amerini S, Granger HJ, Maggi CA, Geppeti P, Ledda F (1994): Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by Substance P. J Clin Invest 94:2036-2044.