A recombinant transductor-effector system: In vitro study of G inhibitory protein (G-alpha-i1) direct activators

Archives of Biochemistry and Biophysics

Volumn 453, Issue 2, 2006, Pages 151-160

  Cesare Mannelli, Lorenzo Di ^a   Pacini, Alessandra ^a   Toscano, Annarita ^a   Ghelardini, Carla ^a   Manetti, Dina ^a   Gualtieri, Fulvio ^a   Patel, Tarun B ^b   Bartolini, Alessandro ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Adenylate cyclase; Direct activator; G protein; Mastoparan; Myristoylation; Protein coexpression

Indexed keywords

ADENYLATE CYCLASE; BC 5; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; ISOPROTEIN; MASTOPARAN; ML 250; MYRISTOYLTRANSFERASE; N DODECYLLYSINAMIDE; PIPERIDINE DERIVATIVE; TRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; CELL FREE SYSTEM; CYTOSOL; DRUG PROTEIN BINDING; ESCHERICHIA COLI; EVALUATION; MOLECULAR CLONING; MOLECULAR INTERACTION; MYRISTYLATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROKARYOTE; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REACTION ANALYSIS; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; SYNTHESIS;

ADENYLATE CYCLASE; ENZYME ACTIVATION; ESCHERICHIA COLI; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; TRANSDUCTION, GENETIC;

ESCHERICHIA COLI; MAMMALIA; PROKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 33748425409     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2006.07.006     Document Type: Article

References (32)

1. Gilman A.G. Annu. Rev. Biochem. 56 (1987) 615-649
2. Neves S.R., Ram P.T., and Iyengar R. Science 296 (2002) 1636-1639
3. Landry Y., and Gies J.P. Mini. Rev. Med. Chem. 2 (2002) 361-372
4. Cabrera-Vera T.M., Vanhauwe J., Thomas T.O., Medkova M., Preininger A., Mazzoni M.R., and Hamm H.E. Endocr. Rev. 24 (2003) 765-781
5. Lanier S.M. Biol. Cell. 96 (2004) 369-372
6. Spiegel A.M., and Weinstein L.S. Annu. Rev. Med. 55 (2004) 27-39
7. Lyons J., Landis C.A., Harsh G., Vallar L., Grunewald K., Feichtinger H., Duh Q.Y., Clark O.H., Kawasaki E., Bourne H.R., et al. Science 249 (1990) 655-659
8. Williamson E.A., Ince P.G., Harrison D., Kendall-Taylor P., and Harris P.E. Eur. J. Clin. Invest. 25 (1995) 128-131
9. Lerman B.B., Dong B., Stein K.M., Markovitz S.M., Linden J., and Catanzaro D.F. J. Clin. Invest. 101 (1998) 2862-2868
10. Galeotti N., Ghelardini C., Zoppi M., Del Bene E., Raimondi L., Beneforti E., and Bartolini A. J. Rheumatol. 28 (2001) 2298-2304
11. Galeotti N., Ghelardini C., Zoppi M., Del Bene E., Raimondi L., Beneforti E., and Bartolini A. Cephalalgia 21 (2001) 38-45
12. Laugwitz K.L., Allgeier A., Offermans S., Spicher K., Van Sande J., Dumont J.E., and Schultz G. Proc. Natl. Acad. Sci. USA 93 (1996) 116-120
13. Akhter S.A., Luttrell L.M., Rockman H.A., Iaccarino G., Lefkowitz R.J., and Koch W.J. Science 280 (1998) 574-577
14. Höller C., Freissmuth M., and Nanoff C. Cell. Mol. Life. Sci. 55 (1999) 257-270
15. Nürnberg B., Tögel W., Krause G., Storm R., Breitweg-Lehmann E., and Schunack W. Eur. J. Med. Chem. 34 (1999) 5-30
16. Ja W.W., and Roberts R.W. Trends Biochem. Sci. 30 (2005) 318-324
17. Odagaki Y., Nishi N., and Koyama T. Life Sci. 62 (1998) 1537-1541
18. Lesckhe C., Storm R., Breitweg E., Exner T., Nürnberg B., and Schunack W. J. Med. Chem. 40 (1997) 3130-3139
19. Breitweg-Lehmann E., Czupalla C., Storm R., Kudlacek O., Schunack W., Freissmuth M., and Nürnberg B. Mol. Pharmacol. 61 (2002) 628-636
20. Manetti D., Di Cesare Mannelli L., Dei S., Galeotti N., Ghelardini C., Romanelli M.N., Scapecchi S., Teodori E., Pacini A., Bartolini A., and Gualtieri F. J. Med. Chem. 48 (2005) 6491-6503
21. L. Di Cesare Mannelli, A. Pacini, A. Toscano, M. Fortini, D. Berti, C. Ghelardini, N. Galeotti, P. Baglioni, A. Bartolini, 47 (2006) 303-310.
22. Wittpoth C., Scholich K., Yigzaw Y., Stringfield T.M., and Patel T.B. Proc. Natl. Acad. Sci. USA 96 (1999) 9551-9556
23. Dessauer C.W., Chen-Goodspeed M., and Chen J. J. Biol. Chem. 277 (2002) 28823-28829
24. Linder M.E., Pang I.H., Duronio R.J., Gordon J.I., Sternweis P.J., and Gilman A.G. J. Biol. Chem. 266 (1991) 4654-4659
25. Patel T.B., Wittpoth C., Barbier A.J., Yigzaw Y., and Scholich K. Methods Enzymol. 345 (2002) 160-187
26. Hope M.J., Bally M.B., Webb G., and Cullis P.R. Biochim. Biophys. Acta 812 (1985) 55-65
27. Oppi C., Wagner T., Crisari A., Camerini B., and Tocchini Valentini G.P. Proc. Natl. Acad. Sci. USA 89 (1992) 8268-8272
28. Taussig R., Iniguez-Lluhi J.A., and Gilman A.G. Science 261 (1993) 218-221
29. Mumby S.M., Heuckeroth R.O., Gordon J.I., and Gilman A.G. Proc. Natl. Acad. Sci. USA 87 (1990) 728-732
30. Mumby S.M., and Linder M.E. Meth. Enzymol. 237 (1994) 254-268
31. Stebbins C.E., Jr Kaelin W.G.T., and Pavletich N.P. Science 284 (1999) 455-461
32. Sambrook J., Fritsch E.F., and Maniatis T. Molecular Cloning: A Laboratory Manual. 2nd ed. (1989), Cold Spring Harbor Laboratory, Cold Spring Harbor, NY