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Volumn 41, Issue 7, 2006, Pages 1139-1150

Cytotoxicity of myeloperoxidase/nitrite-oxidized low-density lipoprotein toward endothelial cells is due to a high 7β-hydroxycholesterol to 7-ketocholesterol ratio

Author keywords

Cytotoxicity; Endothelial cells; Epicatechin; Flavonoids; HUVEC; Lipid peroxidation; Myeloperoxidase; Oxidative stress; oxLDL; Oxysterols

Indexed keywords

7 OXOCHOLESTEROL; 7BETA HYDROXYCHOLESTEROL; APOCYNIN; COPPER; DNA FRAGMENT; EPICATECHIN; HYDROGEN PEROXIDE; LOW DENSITY LIPOPROTEIN; MYELOPEROXIDASE; NITRITE; OXYSTEROL; POLYPHENOL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

EID: 33748318022     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2006.06.027     Document Type: Article
Times cited : (30)

References (67)
  • 1
    • 0026657363 scopus 로고
    • The role of lipid peroxidation and antioxidants in oxidative modification of LDL
    • Esterbauer H., Gebicki J., Puhl H., and Jürgens G. The role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Radic. Biol. Med. 13 (1992) 341-390
    • (1992) Free Radic. Biol. Med. , vol.13 , pp. 341-390
    • Esterbauer, H.1    Gebicki, J.2    Puhl, H.3    Jürgens, G.4
  • 2
    • 0035181940 scopus 로고    scopus 로고
    • Mechanisms for oxidizing low-density lipoprotein. Insights from patterns of oxidation products in the artery wall and from mouse models of atherosclerosis
    • Gaut J.P., and Heinecke J.W. Mechanisms for oxidizing low-density lipoprotein. Insights from patterns of oxidation products in the artery wall and from mouse models of atherosclerosis. Trends Cardiovasc. Med. 11 (2001) 103-112
    • (2001) Trends Cardiovasc. Med. , vol.11 , pp. 103-112
    • Gaut, J.P.1    Heinecke, J.W.2
  • 3
    • 0036729270 scopus 로고    scopus 로고
    • Luca, Oxidation of low-density lipoprotein in atherosclerosis from basic biochemistry to clinical studies
    • Albertini R., Moratti R., and De G. Luca, Oxidation of low-density lipoprotein in atherosclerosis from basic biochemistry to clinical studies. Curr. Mol. Med. 2 (2002) 579-592
    • (2002) Curr. Mol. Med. , vol.2 , pp. 579-592
    • Albertini, R.1    Moratti, R.2    De, G.3
  • 4
    • 4644310560 scopus 로고    scopus 로고
    • Role of oxidative modifications in atherosclerosis
    • Stocker R., and Keaney Jr. J.F. Role of oxidative modifications in atherosclerosis. Physiol. Rev. 84 (2004) 1381-1478
    • (2004) Physiol. Rev. , vol.84 , pp. 1381-1478
    • Stocker, R.1    Keaney Jr., J.F.2
  • 5
    • 3042827082 scopus 로고    scopus 로고
    • Oxysterol mixtures prevent proapoptotic effects of 7-ketocholesterol in macrophages: implications for proatherogenic gene modulation
    • Epub 2004 Feb 20
    • Biasi F., Leonarduzzi G., Vizio B., Zanetti D., Sevanian A., Sottero B., Verde V., Zingaro B., Chiarpotto E., and Poli G. Oxysterol mixtures prevent proapoptotic effects of 7-ketocholesterol in macrophages: implications for proatherogenic gene modulation. FASEB J. 18 (2004) 693-695 Epub 2004 Feb 20
    • (2004) FASEB J. , vol.18 , pp. 693-695
    • Biasi, F.1    Leonarduzzi, G.2    Vizio, B.3    Zanetti, D.4    Sevanian, A.5    Sottero, B.6    Verde, V.7    Zingaro, B.8    Chiarpotto, E.9    Poli, G.10
  • 6
    • 0032754476 scopus 로고    scopus 로고
    • Oxysterols from oxidized LDL are cytotoxic but fail to induce hsp70 expression in endothelial cells
    • Pirillo A., Zhu W., Roma P., Galli G., Caruso D., Pelegatta F., and Catapano A.L. Oxysterols from oxidized LDL are cytotoxic but fail to induce hsp70 expression in endothelial cells. FEBS Lett. 462 (1999) 113-116
    • (1999) FEBS Lett. , vol.462 , pp. 113-116
    • Pirillo, A.1    Zhu, W.2    Roma, P.3    Galli, G.4    Caruso, D.5    Pelegatta, F.6    Catapano, A.L.7
  • 8
    • 0035091665 scopus 로고    scopus 로고
    • Coronary atherosclerosis and oxidative stress as reflected by autoantibodies against low-density lipoprotein and oxysterols
    • Yosunobu Y., Hajashi K., Shingu T., Yamagata T., Kajiyama G., and Kambe M. Coronary atherosclerosis and oxidative stress as reflected by autoantibodies against low-density lipoprotein and oxysterols. Atherosclerosis 155 (2001) 445-453
    • (2001) Atherosclerosis , vol.155 , pp. 445-453
    • Yosunobu, Y.1    Hajashi, K.2    Shingu, T.3    Yamagata, T.4    Kajiyama, G.5    Kambe, M.6
  • 10
    • 0030008367 scopus 로고    scopus 로고
    • Sterol efflux is impaired from macrophage foam cells selectively enriched with 7-ketocholesterol
    • Gelissen I.C., Brown A.J., Mander E.L., Kritharides L., Dean R.T., and Jessup W. Sterol efflux is impaired from macrophage foam cells selectively enriched with 7-ketocholesterol. J. Biol. Chem. 271 (1996) 17852-17860
    • (1996) J. Biol. Chem. , vol.271 , pp. 17852-17860
    • Gelissen, I.C.1    Brown, A.J.2    Mander, E.L.3    Kritharides, L.4    Dean, R.T.5    Jessup, W.6
  • 13
    • 0034659164 scopus 로고    scopus 로고
    • Myeloperoxidase-generated oxidants and atherosclerosis
    • Podrez E.A., Abu-Saud H.M., and Hazen S.L. Myeloperoxidase-generated oxidants and atherosclerosis. Free Radic. Biol. Med. 28 (2000) 1717-1725
    • (2000) Free Radic. Biol. Med. , vol.28 , pp. 1717-1725
    • Podrez, E.A.1    Abu-Saud, H.M.2    Hazen, S.L.3
  • 14
    • 18844414955 scopus 로고    scopus 로고
    • Myeloperoxidase-induced lipid peroxidation of LDL in the presence of nitrite. Protection by cocoa flavanols
    • Schewe T., and Sies H. Myeloperoxidase-induced lipid peroxidation of LDL in the presence of nitrite. Protection by cocoa flavanols. BioFactors 24 (2005) 49-58
    • (2005) BioFactors , vol.24 , pp. 49-58
    • Schewe, T.1    Sies, H.2
  • 15
    • 0028292033 scopus 로고
    • Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions
    • Daugherty A., Dunn J.L., Rateri D.L., and Heinecke J.W. Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions. J. Clin. Invest. 94 (1994) 437-444
    • (1994) J. Clin. Invest. , vol.94 , pp. 437-444
    • Daugherty, A.1    Dunn, J.L.2    Rateri, D.L.3    Heinecke, J.W.4
  • 16
    • 0034731356 scopus 로고    scopus 로고
    • Myeloperoxidase binds to low-density lipoprotein; potential implications for atherosclerosis
    • Carr A.C., Myzak M.C., Stocker R., McCall M.R., and Frei B. Myeloperoxidase binds to low-density lipoprotein; potential implications for atherosclerosis. FEBS Lett. 487 (2000) 176-180
    • (2000) FEBS Lett. , vol.487 , pp. 176-180
    • Carr, A.C.1    Myzak, M.C.2    Stocker, R.3    McCall, M.R.4    Frei, B.5
  • 17
    • 0032701646 scopus 로고    scopus 로고
    • Myeloperoxidase-generated reactive nitrogen species convert LDL in its atherogenic form in vitro
    • Podrez E.A., Schmitt D., Hoff H.F., and Hazen S.L. Myeloperoxidase-generated reactive nitrogen species convert LDL in its atherogenic form in vitro. J. Clin. Invest. 103 (1999) 1547-1560
    • (1999) J. Clin. Invest. , vol.103 , pp. 1547-1560
    • Podrez, E.A.1    Schmitt, D.2    Hoff, H.F.3    Hazen, S.L.4
  • 20
    • 5044238300 scopus 로고    scopus 로고
    • Oxidative modification of low-density lipoprotein: lipid peroxidation by myeloperoxidase in the presence of nitrite
    • Kraemer T., Prakosay I., Date R.A., Sies H., and Schewe T. Oxidative modification of low-density lipoprotein: lipid peroxidation by myeloperoxidase in the presence of nitrite. Biol. Chem. 385 (2004) 809-918
    • (2004) Biol. Chem. , vol.385 , pp. 809-918
    • Kraemer, T.1    Prakosay, I.2    Date, R.A.3    Sies, H.4    Schewe, T.5
  • 25
    • 1442274617 scopus 로고    scopus 로고
    • Flavanol-rich cocoa induces nitric oxide-dependent vasodilation in healthy humans
    • Fisher N.D.L., Hughes M., Gerhard-Herman M., and Hollenberg N.K. Flavanol-rich cocoa induces nitric oxide-dependent vasodilation in healthy humans. J. Hypertens 21 (2003) 2281-2286
    • (2003) J. Hypertens , vol.21 , pp. 2281-2286
    • Fisher, N.D.L.1    Hughes, M.2    Gerhard-Herman, M.3    Hollenberg, N.K.4
  • 27
    • 33644599022 scopus 로고    scopus 로고
    • Cocoa intake, Blood pressure, and cardiovascular mortality. The Zutphen Elderly Study
    • Buijsse B., Feskens E.J.M., Kok F.J., and Kromhout D. Cocoa intake, Blood pressure, and cardiovascular mortality. The Zutphen Elderly Study. Arch. Intern. Med. 166 (2006) 411-417
    • (2006) Arch. Intern. Med. , vol.166 , pp. 411-417
    • Buijsse, B.1    Feskens, E.J.M.2    Kok, F.J.3    Kromhout, D.4
  • 29
    • 18844369559 scopus 로고    scopus 로고
    • Epicatechin protects endothelial cells against oxidized LDL and maintains NO synthase
    • Steffen Y., Schewe T., and Sies H. Epicatechin protects endothelial cells against oxidized LDL and maintains NO synthase. Biochem. Biophys. Res. Commun. 331 (2005) 1277-1283
    • (2005) Biochem. Biophys. Res. Commun. , vol.331 , pp. 1277-1283
    • Steffen, Y.1    Schewe, T.2    Sies, H.3
  • 30
    • 0026476406 scopus 로고
    • Improved measurement of low-density lipoprotein susceptibility to copper-induced oxidation: application of a short procedure for isolating low-density lipoprotein
    • Kleinveld H.A., Hak-Lemmers H.L., Stalenhoef A.F., and Demacker P.N. Improved measurement of low-density lipoprotein susceptibility to copper-induced oxidation: application of a short procedure for isolating low-density lipoprotein. Clin. Chem. 38 (1992) 2066-2072
    • (1992) Clin. Chem. , vol.38 , pp. 2066-2072
    • Kleinveld, H.A.1    Hak-Lemmers, H.L.2    Stalenhoef, A.F.3    Demacker, P.N.4
  • 31
    • 0024555858 scopus 로고
    • Studies on oxidized low density lipoproteins. Controlled oxidation and a prostaglandin artifact
    • Zhang H.F., Davis W.B., Chen X.S., Whisler R.L., and Cornwell D.G. Studies on oxidized low density lipoproteins. Controlled oxidation and a prostaglandin artifact. J. Lipid Res. 30 (1989) 141-148
    • (1989) J. Lipid Res. , vol.30 , pp. 141-148
    • Zhang, H.F.1    Davis, W.B.2    Chen, X.S.3    Whisler, R.L.4    Cornwell, D.G.5
  • 32
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh E.G., and Dyer W.J. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37 (1959) 911-917
    • (1959) Can. J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 33
    • 0025776831 scopus 로고
    • Cholesterol feeding increases plasma and aortic tissue cholesterol oxide levels in parallel: further evidence for the role of cholesterol oxidation in atherosclerosis
    • Hodis H.N., Crawford D.W., and Sevanian A. Cholesterol feeding increases plasma and aortic tissue cholesterol oxide levels in parallel: further evidence for the role of cholesterol oxidation in atherosclerosis. Atherosclerosis 89 (1991) 117-126
    • (1991) Atherosclerosis , vol.89 , pp. 117-126
    • Hodis, H.N.1    Crawford, D.W.2    Sevanian, A.3
  • 34
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application for proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application for proliferation and cytotoxicity assays. J. Immunol. Methods 65 (1983) 55-63
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 35
    • 0015383455 scopus 로고
    • Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr J.F.R., Wyllie A.H., and Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26 (1972) 239-257
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 36
    • 0028985261 scopus 로고
    • Self-association of the "death domains" of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects
    • Boldin M.P., Mett I.L., Varfolomeev E.E., Chumakov I., Shemer-Avni Y., Camonis J.H., and Wallach D. Self-association of the "death domains" of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects. J. Biol. Chem. 270 (1995) 7795-7798
    • (1995) J. Biol. Chem. , vol.270 , pp. 7795-7798
    • Boldin, M.P.1    Mett, I.L.2    Varfolomeev, E.E.3    Chumakov, I.4    Shemer-Avni, Y.5    Camonis, J.H.6    Wallach, D.7
  • 38
    • 0030820068 scopus 로고    scopus 로고
    • 7-Hydroperoxycholesterol and its products in oxidized low density lipoprotein and human atherosclerotic plaque
    • Brown A.J., Leong S., Dean R.T., and Jessup W. 7-Hydroperoxycholesterol and its products in oxidized low density lipoprotein and human atherosclerotic plaque. J. Lipid Res. 38 (1997) 1730-1745
    • (1997) J. Lipid Res. , vol.38 , pp. 1730-1745
    • Brown, A.J.1    Leong, S.2    Dean, R.T.3    Jessup, W.4
  • 39
    • 0030454202 scopus 로고    scopus 로고
    • Formation of oxysterols during oxidation of low-density lipoprotein by peroxynitrite, myoglobin and copper
    • Patel R.P., Diczfalusy U., Dzeletovic S., Wilson M.T., and Darley-Usmar V.M. Formation of oxysterols during oxidation of low-density lipoprotein by peroxynitrite, myoglobin and copper. J. Lipid Res. 37 (1996) 2361-2371
    • (1996) J. Lipid Res. , vol.37 , pp. 2361-2371
    • Patel, R.P.1    Diczfalusy, U.2    Dzeletovic, S.3    Wilson, M.T.4    Darley-Usmar, V.M.5
  • 40
    • 0033779395 scopus 로고    scopus 로고
    • Stimulation of NADPH oxidase by oxidized low-density lipoprotein induces proliferation of human vascular endothelial cells
    • Heinloth A., Heermeier K., Raff U., Wanner C., and Galle J. Stimulation of NADPH oxidase by oxidized low-density lipoprotein induces proliferation of human vascular endothelial cells. J. Am. Soc. Nephrol. 11 (2000) 1819-1825
    • (2000) J. Am. Soc. Nephrol. , vol.11 , pp. 1819-1825
    • Heinloth, A.1    Heermeier, K.2    Raff, U.3    Wanner, C.4    Galle, J.5
  • 41
    • 0035834028 scopus 로고    scopus 로고
    • Induction of NAD(P)H oxidase by oxidized low-density lipoprotein in human endothelial cells: antioxidative potential of hydroxymethylglutaryl coenzyme A reductase inhibitor therapy
    • Rueckschloss U., Galle J., Holtz J., Zerkowski H.R., and Morawietz H. Induction of NAD(P)H oxidase by oxidized low-density lipoprotein in human endothelial cells: antioxidative potential of hydroxymethylglutaryl coenzyme A reductase inhibitor therapy. Circulation 104 (2001) 1767-1772
    • (2001) Circulation , vol.104 , pp. 1767-1772
    • Rueckschloss, U.1    Galle, J.2    Holtz, J.3    Zerkowski, H.R.4    Morawietz, H.5
  • 42
    • 33646130154 scopus 로고    scopus 로고
    • The NADPH oxidase inhibitor apocynin (acetovanillone) induces oxidative stress
    • Riganti C., Costamagna C., Bosia A., and Ghigo D. The NADPH oxidase inhibitor apocynin (acetovanillone) induces oxidative stress. Toxicol. Appl. Pharmacol. 212 (2006) 179-187
    • (2006) Toxicol. Appl. Pharmacol. , vol.212 , pp. 179-187
    • Riganti, C.1    Costamagna, C.2    Bosia, A.3    Ghigo, D.4
  • 43
    • 0027533505 scopus 로고
    • Ebselen, a selenoorganic compound as glutathione peroxidase mimic
    • Sies H. Ebselen, a selenoorganic compound as glutathione peroxidase mimic. Free Radic. Biol. Med. 14 (1993) 313-323
    • (1993) Free Radic. Biol. Med. , vol.14 , pp. 313-323
    • Sies, H.1
  • 44
    • 0029114721 scopus 로고
    • Molecular actions of ebselen-An antiinflammatory antioxidant
    • Schewe T. Molecular actions of ebselen-An antiinflammatory antioxidant. Gen. Pharmacol. 26 (1995) 1153-1169
    • (1995) Gen. Pharmacol. , vol.26 , pp. 1153-1169
    • Schewe, T.1
  • 45
    • 0026636515 scopus 로고
    • Antioxidant effect of ebselen (PZ 51): peroxidase mimetic activity on phospholipid and cholesterol hydroperoxides vs free radical scavenger activity
    • Maiorino M., Roveri A., and Ursini F. Antioxidant effect of ebselen (PZ 51): peroxidase mimetic activity on phospholipid and cholesterol hydroperoxides vs free radical scavenger activity. Arch. Biochem. Biophys. 295 (1992) 404-409
    • (1992) Arch. Biochem. Biophys. , vol.295 , pp. 404-409
    • Maiorino, M.1    Roveri, A.2    Ursini, F.3
  • 46
    • 0027409382 scopus 로고
    • Lethal damage to endothelial cells by oxidized low density lipoprotein: role of selenoperoxidases in cytoprotection against lipid hydroperoxide- and iron-mediated reactions
    • Thomas J.P., Geiger P.G., and Girotti A.W. Lethal damage to endothelial cells by oxidized low density lipoprotein: role of selenoperoxidases in cytoprotection against lipid hydroperoxide- and iron-mediated reactions. J. Lipid Res. 34 (1993) 479-490
    • (1993) J. Lipid Res. , vol.34 , pp. 479-490
    • Thomas, J.P.1    Geiger, P.G.2    Girotti, A.W.3
  • 47
    • 0028046440 scopus 로고
    • Human blood cells support the reduction of low-density-lipoprotein-associated cholesteryl ester hydroperoxides by albumin-bound ebselen
    • Christison J., Sies H., and Stocker R. Human blood cells support the reduction of low-density-lipoprotein-associated cholesteryl ester hydroperoxides by albumin-bound ebselen. Biochem.J. 304 (1994) 341-345
    • (1994) Biochem.J. , vol.304 , pp. 341-345
    • Christison, J.1    Sies, H.2    Stocker, R.3
  • 48
    • 0034602533 scopus 로고    scopus 로고
    • Two-electron reduction and one-electron oxidation of organic hydroperoxides by human myeloperoxidase
    • Furtmüller P.G., Burner U., Jantschko W., Regelsberger G., and Obinger C. Two-electron reduction and one-electron oxidation of organic hydroperoxides by human myeloperoxidase. FEBS Lett. 484 (2000) 139-143
    • (2000) FEBS Lett. , vol.484 , pp. 139-143
    • Furtmüller, P.G.1    Burner, U.2    Jantschko, W.3    Regelsberger, G.4    Obinger, C.5
  • 49
    • 0030908862 scopus 로고    scopus 로고
    • Characterization of cholesterol oxidation products formed by oxidative modification of low-density lipoprotein
    • Chang Y.H., Abdalla D.S.P., and Sevanian A. Characterization of cholesterol oxidation products formed by oxidative modification of low-density lipoprotein. Free Radic. Biol. Med. 23 (1997) 202-214
    • (1997) Free Radic. Biol. Med. , vol.23 , pp. 202-214
    • Chang, Y.H.1    Abdalla, D.S.P.2    Sevanian, A.3
  • 51
    • 0030909465 scopus 로고    scopus 로고
    • Formation of reactive nitrogen species during peroxidase-catalyzed oxidation of nitrite. A potential additional mechanism of nitric oxide-dependent toxicity
    • van der Vliet A., Eiserich J.P., Halliwell B., and Cross C.E. Formation of reactive nitrogen species during peroxidase-catalyzed oxidation of nitrite. A potential additional mechanism of nitric oxide-dependent toxicity. J. Biol. Chem. 272 (1997) 7617-7625
    • (1997) J. Biol. Chem. , vol.272 , pp. 7617-7625
    • van der Vliet, A.1    Eiserich, J.P.2    Halliwell, B.3    Cross, C.E.4
  • 53
    • 0025831893 scopus 로고
    • Chromatographic separation and electrochemical determination of cholesterol hydroperoxides generated by photodynamic action
    • Korytowski W., Bachowski G.J., and Girotti A.W. Chromatographic separation and electrochemical determination of cholesterol hydroperoxides generated by photodynamic action. Anal. Biochem. 197 (1991) 149-156
    • (1991) Anal. Biochem. , vol.197 , pp. 149-156
    • Korytowski, W.1    Bachowski, G.J.2    Girotti, A.W.3
  • 54
    • 0026889241 scopus 로고
    • Photoperoxidation of cholesterol in homogeneous solution, isolated membranes, and cells: comparison of the 5 alpha- and 6 beta-hydroperoxides as indicators of singlet oxygen intermediacy
    • Korytowski W., Bachowski G.J., and Girotti A.W. Photoperoxidation of cholesterol in homogeneous solution, isolated membranes, and cells: comparison of the 5 alpha- and 6 beta-hydroperoxides as indicators of singlet oxygen intermediacy. Photochem. Photobiol. 56 (1992) 1-8
    • (1992) Photochem. Photobiol. , vol.56 , pp. 1-8
    • Korytowski, W.1    Bachowski, G.J.2    Girotti, A.W.3
  • 55
    • 0034534961 scopus 로고    scopus 로고
    • Nitric oxide is a physiological substrate for mammalian peroxidases
    • Abu-Soud H.M., and Hazen S.L. Nitric oxide is a physiological substrate for mammalian peroxidases. J. Biol. Chem. 275 (2000) 37524-37532
    • (2000) J. Biol. Chem. , vol.275 , pp. 37524-37532
    • Abu-Soud, H.M.1    Hazen, S.L.2
  • 59
    • 13244288627 scopus 로고    scopus 로고
    • 7-Ketocholesterol enhances the expression of adhesion molecules on human aortic endothelial cells by increasing the production of reactive oxygen species
    • Shimozawa M., Naito Y., Manabe H., Uchiyama K., Kuroda M., Katada K., Yoshida N., and Yoshikawa T. 7-Ketocholesterol enhances the expression of adhesion molecules on human aortic endothelial cells by increasing the production of reactive oxygen species. Redox Rep. 9 (2004) 370-375
    • (2004) Redox Rep. , vol.9 , pp. 370-375
    • Shimozawa, M.1    Naito, Y.2    Manabe, H.3    Uchiyama, K.4    Kuroda, M.5    Katada, K.6    Yoshida, N.7    Yoshikawa, T.8
  • 61
    • 0033593070 scopus 로고    scopus 로고
    • Leukocytes utilize myeloperoxidase-generated nitrating intermediates as physiological catalysts for the generation of biologically active oxidized lipids and sterols in serum
    • Schmitt D., Shen Z., Zhang R., Colles S.M., Wu W., Salomon R.G., Chen Y., Chisolm G.M., and Hazen S.L. Leukocytes utilize myeloperoxidase-generated nitrating intermediates as physiological catalysts for the generation of biologically active oxidized lipids and sterols in serum. Biochemistry 38 (1999) 16904-16915
    • (1999) Biochemistry , vol.38 , pp. 16904-16915
    • Schmitt, D.1    Shen, Z.2    Zhang, R.3    Colles, S.M.4    Wu, W.5    Salomon, R.G.6    Chen, Y.7    Chisolm, G.M.8    Hazen, S.L.9
  • 62
    • 0028787428 scopus 로고
    • In vitro cell injury by oxidized low density lipoprotein involves lipid hydroperoxide-induced formation of alkoxyl, lipid, and peroxyl radicals
    • Coffey M.D., Cole R.A., Colles S.M., and Chisolm G.M. In vitro cell injury by oxidized low density lipoprotein involves lipid hydroperoxide-induced formation of alkoxyl, lipid, and peroxyl radicals. J. Clin. Invest. 96 (1995) 1866-1873
    • (1995) J. Clin. Invest. , vol.96 , pp. 1866-1873
    • Coffey, M.D.1    Cole, R.A.2    Colles, S.M.3    Chisolm, G.M.4
  • 63
    • 0029795501 scopus 로고    scopus 로고
    • Roles of multiple oxidized LDL lipids in cellular injury: dominance of 7beta-hydroperoxycholesterol
    • Colles S.M., Irwin K.C., and Chisolm G.M. Roles of multiple oxidized LDL lipids in cellular injury: dominance of 7beta-hydroperoxycholesterol. J. Lipid Res. 37 (1996) 2018-2028
    • (1996) J. Lipid Res. , vol.37 , pp. 2018-2028
    • Colles, S.M.1    Irwin, K.C.2    Chisolm, G.M.3
  • 64
    • 33644634175 scopus 로고    scopus 로고
    • Foam cell death induced by 7β-hydroxycholesterol is mediated by labile iron-driven oxidative injury: mechanisms underlying induction of ferritin in human atheroma
    • Li W., Hellsten A., Xu L.-H., Zhuang D.-M., Jansson K., Brunk U.T., and Yuan X.-M. Foam cell death induced by 7β-hydroxycholesterol is mediated by labile iron-driven oxidative injury: mechanisms underlying induction of ferritin in human atheroma. Free Radic. Biol. Med. 39 (2005) 864-875
    • (2005) Free Radic. Biol. Med. , vol.39 , pp. 864-875
    • Li, W.1    Hellsten, A.2    Xu, L.-H.3    Zhuang, D.-M.4    Jansson, K.5    Brunk, U.T.6    Yuan, X.-M.7
  • 65
    • 0037468521 scopus 로고    scopus 로고
    • Myeloperoxidase/nitrite-mediated lipid peroxidation of low-density lipoprotein as modulated by flavonoids
    • Kostyuk V.A., Kraemer T., Sies H., and Schewe T. Myeloperoxidase/nitrite-mediated lipid peroxidation of low-density lipoprotein as modulated by flavonoids. FEBS Lett. 537 (2003) 146-150
    • (2003) FEBS Lett. , vol.537 , pp. 146-150
    • Kostyuk, V.A.1    Kraemer, T.2    Sies, H.3    Schewe, T.4
  • 66
    • 24344459055 scopus 로고    scopus 로고
    • Differential inhibition of oxidized LDL-induced apoptosis in human endothelial cells treated with different flavonoids
    • Jeong Y.-J., Choi Y.-J., Kwon H.-M., Kang S.-W., Park H.-S., Lee M., and Kang Y.-H. Differential inhibition of oxidized LDL-induced apoptosis in human endothelial cells treated with different flavonoids. Br. J. Nutr. 93 (2005) 581-591
    • (2005) Br. J. Nutr. , vol.93 , pp. 581-591
    • Jeong, Y.-J.1    Choi, Y.-J.2    Kwon, H.-M.3    Kang, S.-W.4    Park, H.-S.5    Lee, M.6    Kang, Y.-H.7
  • 67
    • 29344455162 scopus 로고    scopus 로고
    • Kaempferol inhibits apoptosis in vascular smooth muscle induced by a component of oxidized LDL
    • Ruiz E., Padilla E., Redondo S., Gordillo-Moscoso A., and Tejerina T. Kaempferol inhibits apoptosis in vascular smooth muscle induced by a component of oxidized LDL. Eur. J. Pharmacol. 529 (2006) 79-83
    • (2006) Eur. J. Pharmacol. , vol.529 , pp. 79-83
    • Ruiz, E.1    Padilla, E.2    Redondo, S.3    Gordillo-Moscoso, A.4    Tejerina, T.5


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