Effect of transforming growth factor-beta 1 (TGF-ß1) released from a scaffold on chondrogenesis in an osteochondral defect model in the rabbit

Central European Journal of Biology

Volumn 1, Issue 1, 2006, Pages 43-60

  Cucchiarini, Magali ^a   Sohier, Jerome ^b   Mitosch, Karin ^a   Kaul, Gunter ^a   Zurakowski, David ^c   Bezemer, Jeroen M ^b,d   Kohn, Dieter ^a   Madry, Henning ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b OctoPlus NV   (Netherlands)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d AMGEN INC   (United States)

Author keywords

Cartilage defects; Cartilage repair; Rabbit; Scaffold; TGF 1; Transplantation

Indexed keywords

ORYCTOLAGUS CUNICULUS;

EID: 33748316616     PISSN: 1895104X     EISSN: 16443632     Source Type: Journal    
DOI: 10.2478/s11535-006-0004-8     Document Type: Article

References (31)

1. S.W. O'Driscoll: "The healing and regeneration of articular cartilage", J. Bone Joint Surg. Am., Vol. 80, (1998), pp. 1795-1812.
2. E.B. Hunziker: "Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects", Osteoarthr. Cartil., Vol. 10, (2002), pp. 432-463.
3. F. Shapiro, S. Koide and M.J. Glimcher: "Cell origin and differentiation in the repair of full-thickness defects of articular cartilage", J. Bone Joint Surg. Am., Vol. 75, (1993), pp. 532-553.
4. J.A. Buckwalter and H.J. Mankin: "Articular cartilage: degeneration and osteoarthritis, repair, regeneration, and transplantation", Instr. Course Lect., Vol. 47, (1998), pp. 487-504.
5. S.B. Trippel: "Growth factor actions on articular cartilage", J. Rheumatol. Suppl., Vol. 43, (1995), pp. 129-132.
6. E. Grimaud, D. Heymann and F. Redini: "Recent advances in TGF-beta effects on chondrocyte metabolism. Potential therapeutic roles of TGF-beta in cartilage disorders", Cytokine Growth Factor Rev., Vol. 13, (2002), pp. 241-257.
7. I.D. Dinbergs, L. Brown and E.R. Edelman: "Cellular response to transforming growth factor-beta 1 and basic fibroblast growth factor depends on release kinetics and extracellular matrix interactions", J. Biol. Chem., Vol. 271, (1996), pp. 29822-29829.
8. J. Sohier: "Controlled release of TGF-beta 1 from porous polymeric scaffolds for cartilage tissue engineering", submitted, 2006.
9. R. van Dijkhuizen-Radersma, J.R. Roosma, J. Sohier, F.L. Peters, M. van den Doel, C.A. van Blitterswijk, K. de Groot and J.M. Bezemer: "Biodegradable poly(etherester) multiblock copolymers for controlled release applications: An in vivo evaluation", J. Biomed. Mater. Res. A, Vol. 71, (2004), pp. 118-127.
10. T.B. Woodfield, J.M. Bezemer, J.S. Pieper, C.A. van Blitterswijk and J. Riesle: "Scaffolds for tissue engineering of cartilage", Grit. Rev. Eukaryot. Gene Expr., Vol. 12, (2002), pp. 209-236.
11. J. Sohier, R.E. Haan, K. de Groot and J.M. Bezemer: "A novel method to obtain protein release from porous polymer scaffolds: emulsion coating", J. Control. Release, Vol. 87, (2003), pp. 57-68.
12. M. Cucchiarini, H. Madry, C. Ma, T. Thurn, D. Zurakowski, M.D. Menger, D. Kohn, S.B. Trippel and E.F. Terwilliger: "Improved tissue repair in articular cartilage defects in vivo by rAAV-mediated overexpression of human fibroblast growth factor 2", Mol Ther., Vol. 12, (2005), pp. 229-238.
13. H. Madry, G. Kaul, M. Cucchiarini, U. Stein, D. Zurakowski, K. Remberger, M.D. Menger, D. Kohn and S.B. Trippel: "Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I)", Gene Ther., Vol. 12, (2005), pp. 1171-1179.
14. G. Kaul, M. Cucchiarini, D. Arntzen, D. Zurakowski, M.D. Menger, D. Kohn, S.B. Trippel and H. Madry: "Local stimulation of articular cartilage repair by transplantation of encapsulated chondrocytes overexpressing human fibroblast growth factor 2 (FGF-2) in vivo", J. Gene Med., Vol. 8, (2006), pp. 100-111.
15. J.A. Kiernan: Histological and histochemical methods - theory and practice, 3rd ed., Butterworth-Heinemann, Oxford, 1999.
16. A.J. Nixon, L.A. Fortier, J. Williams and H. Mohammed: "Enhanced repair of extensive articular defects by insulin-like growth factor-I-laden fibrin composites", J. Orthop. Res., Vol. 17, (1999), pp. 475-487.
17. L.A. Fortier, H.O. Mohammed, G. Lust and A.J. Nixon: "Insulin-like growth factor-I enhances cell-based repair of articular cartilage", J. Bone Joint Surg. Br., Vol. 84, (2002), pp. 276-288.
18. R.S. Sellers, D. Peluso and E.A. Morris: "The effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) on the healing of full-thickness defects of articular cartilage", J. Bone Joint Surg. Am., Vol. 79, (1997), pp. 1452-1463.
19. R.S. Sellers, R. Zhang, S.S. Glasson, H.D. Kim, D. Peluso, D.A. D'Augusta, K. Beck-with and E.A. Morris: "Repair of articular cartilage defects one year after treatment with recombinant human bone morphogenetic protein-2 (rhBMP-2)", J. Bone Joint Surg. Am., Vol. 82, (2000), pp. 151-160.
20. J.M. Bezemer, R. Radersma, D.W. Grijpma, P.J. Dijkstra, C.A. van Blitterswijk and J. Feijen: "Microspheres for protein delivery prepared from amphiphilic multiblock copolymers. 2. Modulation of release rate", J. Control Release, Vol. 67, (2000), pp. 249-260.
21. R. van Dijkhuizen-Radersma, J.R. Roosma, P. Kaim, S. Metairie, F.L. Peters, J. de Wijn, P. G. Zijlstra, K. de Groot and J.M. Bezemer: "Biodegradable poly (etherester) multiblock copolymers for controlled release applications", J. Biomed. Mater. Res. A, Vol. 67, (2003), pp. 1294-1304.
22. T. Abe, H. Yamada, H. Nakajima, T. Kikuchi, H. Takaishi, T. Tadakuma, K. Fujikawa and Y. Toyama: "Repair of full-thickness cartilage defects using liposomal transforming growth factor-beta 1", J. Orthop. Sci., Vol. 8, (2003), pp. 92-101.
23. C.M. Mierisch, S.B. Cohen, L.C. Jordan, P.G. Robertson, G. Balian and D.R. Diduch: "Transforming growth factor-beta in calcium alginate beads for the treatment of articular cartilage defects in the rabbit", Arthroscopy, Vol. 18, (2002), pp. 892-900.
24. P.R. Elford, M. Graeber, H. Ohtsu, M. Aeberhard, B. Legendre, W.L. Wishart and A.R. MacKenzie: "Induction of swelling, synovial hyperplasia and cartilage proteoglycan loss upon intra-articular injection of transforming growth factor beta-2 in the rabbit", Cytokine, Vol. 4, (1992), pp. 232-238.
25. Z. Mi, S.C. Ghivizzani, E. Lechman, J.C. Glorioso, C.H. Evans and P.D. Robbins: "Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees", Arthritis Re,s Ther., Vol. 5, (2003), pp. R132-R139.
26. T. Takizawa, S. Akizuki, H. Horiuchi and Y. Yasukawa: "Foreign body gonitis caused by a broken poly-L-lactic acid screw", Arthroscopy, Vol. 14, (1998), pp. 329-330.
27. T.A. Holland, E.W. Bodde, L.S. Baggett, Y. Tabata, A.G. Mikos and J.A. Jansen: "Osteochondral repair in the rabbit model utilizing bilayered, degradable oligo(poly(ethylene glycol) fumarate) hydrogel scaffolds", J. Biomed. Mater. Res. A, Vol. 75, (2005), pp. 156-167.
28. C.M. Ferguson, E.M. Schwarz, J.E. Puzas, M.J. Zuscik, H. Drissi and R.J. O'Keefe: "Transforming growth factor-beta 1 induced alteration of skeletal morphogenesis in vivo", J. Orthop. Res., Vol. 22, (2004), pp. 687-696.
29. P. Galera, F. Redini, D. Vivien, J. Bonaventure, H. Penfornis, G. Loyau and J.P. Pujol: "Effect of transforming growth factor-beta 1 (TGF-beta 1) on matrix synthesis by monolayer cultures of rabbit articular chondrocytes during the dedifferentiation process", Exp. Cell Res., Vol. 200, (1992), pp. 379-392.
30. C. Chadjichristos, C. Ghayor, J.F. Herrouin, L. Ala-Kokko, G. Suske, J.P. Pujol and P. Galera: "Down-regulation of human type II collagen gene expression by transforming growth factor-beta 1 (TGF-beta 1) in articular chondrocytes involves SP3/SP1 ratio", J. Biol. Chem., Vol. 277, (2002), pp. 43903-43917.
31. E.B. Hunziker and L.C. Rosenberg: "Repair of partial-thickness defects in articular cartilage: cell recruitment from the synovial membrane", J. Bone Joint Surg. Am., Vol. 78, (1996), pp. 721-733.