Construction of a sIgA-enhancing anti-Porphyromonas gingivalis FimA vaccine and nasal immunization in mice

Immunology Letters

Volumn 107, Issue 1, 2006, Pages 71-75

  Guo, Hongmei ^a   Wang, Xijun ^b   Jiang, Guangshui ^a   Yang, Pishan ^a  

^a SHANDONG UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

DNA vaccine; FimA; Interleukin 15; Nasal; Porphyromonas gingivalis

Indexed keywords

DNA VACCINE; FIMA VACCINE; IMMUNOGLOBULIN A; INTERLEUKIN 15; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; CHO CELL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FIMBRIA; IMMUNE RESPONSE; IMMUNITY; IMMUNIZATION; IMMUNOGLOBULIN BLOOD LEVEL; MALE; MOUSE; NONHUMAN; PLASMID PIRES; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; RECOMBINANT PLASMID; WESTERN BLOTTING;

ADMINISTRATION, INTRANASAL; ANIMALS; BACTEROIDACEAE INFECTIONS; FIMBRIAE PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A, SECRETORY; INTERLEUKIN-15; MICE; MICE, INBRED BALB C; PLASMIDS; PORPHYROMONAS GINGIVALIS; VACCINATION; VACCINES, DNA;

EID: 33748286704     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2006.07.008     Document Type: Article

References (25)

1. Ezzo P., and Cutler C.W. Microorganisms as risk factors for periodontal disease. Periodontology 32 (2000, 2003) 24-35
2. Holt S.C., Kesavalu L., Walker S., and Genco C.A. Virulence factors of Porphyromonas gingivalis. Periodontology 20 (2000, 1999) 168-238
3. Ogawa T., Uchida H., and Hamada S. Porphyromonas gingivalis fimbriae and their synthetic peptides induce proinflammatory cytokines in human peripheral blood monocyte cultures. FEMS Microbiol Lett 116 (1994) 237-342
4. Hamada N., Watanabe K., Sasakawa C., Yoshikawa M., Yoshimura F., and Umemoto T. Construction and characterization of a fimA mutant of Porphyromonas gingivalis. Infect Immun 62 (1994) 1696-1704
5. Evans R.T., Klausen B., Sojar H.T., Bedi G.S., Sfintescu C., Ramamurthy N.S., et al. Immunization with Porphyromonas (Bacteroides) gingivalis fimbriae protects against periodontal destruction. Infect Immun 60 (1992) 2926-2935
6. Kawabata S., Terao Y., Fujiwara T., Nakagawa I., and Hamada S. Targeted salivary gland immunization with plasmid DNA elicits specific salivary immunoglobulin A and G antibodies and serum immunoglobulin G antibodies in mice. Infect Immun 67 (1999) 5863-5868
7. Boyaka P.N., and McGhee J.R. Cytokines as adjuvants for the induction of mucosal immunity. Adv Drug Deliv Rev 51 (2001) 71-79
8. Carson W.E., Giri J.G., Lindemann M.J., Linett M.L., Ahdieh M., Paxton R., et al. Interleukin (IL) 15 is a novel cytoline that activates human natural killer cells via components of the IL-2 receptor. J Exp Med 180 (1994) 1395-1403
9. Schluns K.S., Williams K., Ma A., Zheng X.X., and Lefrancois L. Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells. J Immunol 168 (2001) 4827-4831
10. Armitage R.J., Macduff B.M., Eisenman J., Paxton R., and Grabstein K.H. IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation. J Immunol 154 (1995) 483-490
11. Fujiwara T., Morishima S., Takahashi I., and Hamada S. Molecular cloning and sequencing of the fimbrillin gene of Porphyromonas gingivalis strains and characterization of recombinant proteins. Biochem Biophys Res Comun 197 (1993) 241-247
12. Pachuk C.J., Ciccarelli R.B., Samuel M., Bayer M.E., Trontman R.D., Zurawab D.V., et al. Characterization of a new class of DAN delivery complexes formed by the local anesthetic bupivacaine. Biochim Biophys Acta 1468 (2000) 20-30
13. Bernstein D.I., Tepe E.R., Mester J.C., Arnold R.L., Stanberry L.R., and Higgins T. Effects of DNA immunization formulated with bupivacaine in murine and guinea pig models of genital herpes simplex virus infection. Vaccine 17 (1999) 1964-1969
14. Amano A., Fujiwara T., Nagata H., Kuboniwa M., Sharma A., Sojar H.T., et al. Porphyromonas gingivalis fimbriae mediate coaggregation with Streptococcus oralis through specific domains. J Dent Res 76 (1997) 852-857
15. O'Brien-Simpson N.M., Paolini R.A., and Reynolds E.C. RgpA-Kgp peptide based immunogens probide protection against Porphyromonas gingivalis challenge in a murine lesion model. Infect Immun 68 (2000) 4055-4063
16. Kesavalu J.J., Ebersole J.L., Machen R.L., and Holt S.C. Porphyromonas gingivalis virulence in mice: induction of immunity to bacterial components. Infect Immun 60 (1992) 1455-1464
17. Genco C.A., Potempa J., Mikolajczyk-Pawlinska J., and Travis J. Role of gingipains R in the pathogenesis of Porphyromonas gingivalis in periodontal disease. Clin Infect Dis 28 (1999) 456-465
18. Boyaka P.N., Wright P.F., Marinaro M., Kiyono H., Johnson J.E., Gonzales R.A., et al. Human nasopharyngeal-associated lymphoreticular tissue: functional analysis of subepithelial and intraepithelial B and T cells from adenoids and tonsils. Am J Pathol 157 (2000) 2023-2035
19. Kuper C.F., Koomstra P.J., Hameleers D.M., Bieuienga J., Spit B.J., Duijvestijn A.M., et al. The role of nasopharyngeal lymphoid tissue. Immunol Today 13 6 (1992) 219-224
20. Mestecky J., McGhee J.R., Arnold R.R., Michalek S.M., Prince S.J., and Babb J.L. Selective induction of an immune response in human external secretions by ingestion of bacterial antigen. J Clin Invest 61 (1978) 731-737
21. Toka F.N., Pack C.D., and Rouse B.T. Molecular adjuvants for mucosal immunity. Immunol Rev 199 (2004) 100-112
22. Brandtzaeg P., Farstad I.N., and Haraldsen G. Regional specialization in the mucosal immune system: primed cells do not always home along the same track. Immunol Today 20 (1999) 267-277
23. Kroese F.G., Ammerlaan W.A., and Kantor A.B. Evidence that intestinal IgA plasma cells in m-, k-transgenic mice are derived from B-1 (Ly-1 B) cells. Int Immunol 5 (1993) 1317-1327
24. Hiroi T., Yanagita M., Ohta N., Sakaue G., and Kiyono H. IL-15 and IL-15 receptor selectively regulate differentiation of common mucosal immune system-independent B-1 cells for IgA responses. J Immunol 165 (2000) 4329-4937
25. Shikina T., Hiroi T., Iwatani K., Jang M.H., Fukuyama S., Tamura M., et al. IgA class switch occurs in the organized nasopharynx- and gut-associated lymphoid tissue, but not in the diffuse lamina propria of airways and gut. J Immunol 172 (2004) 6259-6264