Crystal structures of the PLP- and PMP-bound forms of BtrR, a dual functional aminotransferase involved in butirosin biosynthesis

Proteins: Structure, Function and Genetics

Volumn 65, Issue 1, 2006, Pages 220-230

  Popovic, Bojana ^b   Tang, Xiao ^b   Chirgadze, Dimitri Y ^b   Huang, Fanglu ^b   Blundell, Tom L ^b   Spencer, Jonathan B ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b NONE

Author keywords

Aminoglycoside antibiotics; Aminotransferase; Butirosin; Secondary metabolite aminotransferases (SMAT); X ray crystallography

Indexed keywords

2 DEOXYINOSAMINE; 2 DEOXYSCYLLOINOSOSE; 2 DEOXYSTREPTAMINE; AMINODIDEOXYSCYLLOINOSOSE; AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMINOTRANSFERASE; ASPARTIC ACID; BACTERIAL ENZYME; BUTIROSIN; GLYCOSIDE; HOMODIMER; PROTEIN BTRR; PYRIDOXAL 5 PHOSPHATE; PYRIDOXAMINE PHOSPHATE; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BACILLUS CIRCULANS; COVALENT BOND; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; GENE CLUSTER; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; STRUCTURE ANALYSIS; THREE DIMENSIONAL IMAGING; TRANSAMINATION;

AMINO ACID SEQUENCE; BACILLUS; BINDING SITES; COMPUTER SIMULATION; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; MODELS, MOLECULAR; PROTEIN BINDING; PYRIDOXAL PHOSPHATE; PYRIDOXAMINE; TRANSAMINASES;

BACILLUS CIRCULANS;

EID: 33748255080     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21076     Document Type: Article

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