A human origin type II strain of Toxoplasma gondii causing severe encephalitis in mice

Microbes and Infection

Volumn 8, Issue 8, 2006, Pages 2206-2212

  Djurković Djaković, Olgica ^a   Klun, Ivana ^a   Khan, Asis ^b   Nikolić, Aleksandra ^a   Knežević Ušaj, Slavica ^c   Bobić, Branko ^a   Sibley, L David ^b  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NOVI SAD   (Serbia)

Author keywords

Congenital toxoplasmosis; Cytokines; Genotyping; Histopathology; Murine infection; PCR RFLP; Toxoplasma gondii; Type II strains

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CYST; DISEASE SEVERITY; ENCEPHALITIS; EUROPE; FEMALE; FETUS; GENOTYPE; HEPATITIS; HUMAN; INFECTION; INOCULATION; MENINGOENCEPHALITIS; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TOXOPLASMA GONDII; UMBILICAL CORD BLOOD;

MURINAE; OVIS ARIES; TOXOPLASMA GONDII;

EID: 33748208159     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2006.04.016     Document Type: Article

References (24)

1. Remington J.S., McLeod R., Thulliez P., and Desmonts G. Infectious Diseases of the Fetus and Newborn Infant. 5th ed. In: Remington J.S., and Klein J. (Eds) (2001), W.B. Saunders, Philadelphia 205-346
2. Thulliez P. Toxoplasmosis: A Comprehensive Clinical Guide. In: Joynson D.H.M., and Wreghitt T.G. (Eds) (2001), Cambridge University Press, Cambridge 193-213
3. Wilson C., Remington J.S., Stagno S., and Reynolds D. Development of adverse sequelae in children born with subclinical congenital Toxoplasma infection. Pediatrics 66 (1980) 767-774
4. Swisher C., Bozer K., McLeod R., Roizen N., Stein M., Hopkins J., Holfels E., Mets M., Stein L., Patel D., Meier P., Withers S., Remington J., Mack D., Heydeman P., and Patton D. Congenital toxoplasmosis. Semin. Pediatr. Neurol. 1 (1994) 4-25
5. McAuley J., Boyer K.M., Patel D., Mets M., Swisher C., Roizen N., Wolters C., Stein L., Stein M., Schey W., Remington J., Meier P., Johnson D., Heydeman P., Holfels E., Withers S., Mack D., Brown C., Patton D., and McLeod R. Early and longitudinal evaluations of treated infants and children and untreated historical patients with congenital toxoplasmosis: the Chicago Collaborative Treatment Trial. Clin. Infect. Dis. 18 (1994) 38-72
6. Sibley L.D., and Boothroyd J.C. Virulent strains of Toxoplasma gondii comprise a single clonal lineage. Nature 359 (1992) 82-85
7. Howe D.K., and Sibley L.D. Toxoplasma gondii comprises three clonal lineages: correlation of parasite genotype with human disease. J. Infect. Dis. 172 (1995) 1561-1566
8. Howe D.K., Honore S., Dérouin F., and Sibley L.D. Determination of genotypes of Toxoplasma gondii strains isolated from patients with toxoplasmosis. J. Clin. Microbiol. 35 (1997) 1411-1414
9. Ajzenberg D., Cogne N., Paris L., Bessières M.H., Thulliez P., Filisetti D., Pelloux H., Marty P., and Dardé M.L. Genotype of 86 Toxoplasma gondii isolates associated with human congenital toxoplasmosis, and correlation with clinical findings. J. Infect. Dis. 186 (2002) 684-689
10. Ajzenberg D., Bañuls A.L., Su C., Dumètre A., Demar M., Carme B., and Dardé M.L. Genetic diversity, clonality and sexuality in Toxoplasma gondii. Int. J. Parasitol. 34 (2004) 1185-1196
11. Desmonts G., and Remington J.S. Direct agglutination test for diagnosis of Toxoplasma infection: method for increasing sensitivity and specificity. J. Clin. Microbiol. 11 (1980) 562-568
12. Djurković-Djaković O., Nikolić A., Bobić B., Klun I., and Aleksić A. Stage conversion of Toxoplasma gondii RH parasites in mice by treatment with atovaquone and pyrrolidine dithiocarbamate. Microbes Infect. 7 (2005) 49-54
13. Khan A., Su C., German M., Storch G.A., Clifford D.B., and Sibley L.D. Genotyping of Toxoplasma gondii strains from immunocompromised patients reveals high prevalence of type I strains. J. Clin. Microbiol. 43 (2005) 5881-5887
14. McLeod R., Skamene E., Brown C.R., Eisenhauer P.B., and Mack D.G. Genetic regulation of early survival and cyst number after peroral Toxoplasma gondii infection of AxB/BxA recombinant inbred and B10 congenic mice. J. Immunol. 143 (1989) 3031-3034
15. Blackwell J.M., Roberts C.W., and Alexander J. Influence of genes within the MHC on mortality and brain cyst development in mice infected with Toxoplasma gondii: kinetics of immune regulation in BALB H-2 congenic mice. Parasite Immunol. 15 (1993) 317-324
16. Howe D.K., Summers B.C., and Sibley L.D. Acute virulence in mice is associated with markers on chromosome VIII in Toxoplasma gondii. Infect. Immun. 64 (1996) 5193-5198
17. Mordue D.G., Monroy F., La Regina M., Dinarello C.A., and Sibley L.D. Acute toxoplasmosis leads to lethal overproduction of Th1 cytokines. J. Immunol. 167 (2001) 4574-4584
18. Gavrilescu L.C., and Denkers E.Y. IFN-gamma overproduction and high level apoptosis are associated with high but not low virulence Toxoplasma gondii infection. J. Immunol. 167 (2001) 902-909
19. Nguyen T.D., Bigaignon G., Markine-Goriaynoff D., Heremans H., Nguyen T.N., Warnier G., Delmee M., Warny M., Wolf S.F., Uyttenhove C., Van Snick J., and Coutelier J.P. Virulent Toxoplasma gondii strain RH promotes T-cell-independent overproduction of proinflammatory cytokines IL12 and gamma-interferon. J. Med. Microbiol. 52 (2003) 869-876
20. Hunter C.A., Suzuki Y., Subauste C.S., and Remington J.S. Cells and cytokines in resistance to Toxoplasma gondii. Curr. Top. Microbiol. Immunol. 219 (1996) 113-125
21. Denkers E.Y. T lymphocyte-dependent effector mechanisms of immunity to Toxoplasma gondii. Microbes Infect. 1 (1999) 699-708
22. Gazzinelli R.T., Wysocka M., Hayashi S., Denkers E.Y., Hieny S., Caspar P., Trinchieri G., and Sher A. Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii. J. Immunol. 153 (1994) 2533-2543
23. Gazzinelli R.T., Wysocka M., Hieny S., Scharton-Kersten T., Cheever A., Kuhn R., Muller W., Trinchieri G., and Sher A. In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha. J. Immunol. 157 (1996) 798-805
24. Araujo F.G., and Slifer T. Different strains of Toxoplasma gondii induce different cytokine responses in CBA/Ca mice. Infect. Immun. 71 (2003) 4171-4174