Both α-haemolysin determinants contribute to full virulence of uropathogenic Escherichia coli strain 536

Microbes and Infection

Volumn 8, Issue 8, 2006, Pages 2006-2012

  Nagy, Gábor ^a,b   Altenhoefer, Artur ^b   Knapp, Oliver ^c   Maier, Elke ^c   Dobrindt, Ulrich ^b   Blum Oehler, Gabriele ^b   Benz, Roland ^c   Emody, Levente ^a   Hacker, Jörg ^b  

^a UNIVERSITY OF PÉCS   (Hungary)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Cytotoxicity; Gene duplication; Pore formation; Uropathogenic Escherichia coli; Virulence regulation; Haemolysin

Indexed keywords

HEMOLYSIN;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM CULTURE; CHANNEL GATING; CYTOTOXICITY; ELECTROPHYSIOLOGY; ESCHERICHIA COLI; GENE DUPLICATION; LD 50; LIPID MEMBRANE; LUNG TOXICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TARGET CELL; URINARY TRACT INFECTION; UROPATHOGENIC ESCHERICHIA COLI; WILD TYPE;

ESCHERICHIA COLI;

EID: 33748186517     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2006.02.029     Document Type: Article

References (39)

1. Elliott S.J., Srinivas S., Albert M.J., Alam K., Robins-Browne R.M., Gunzburg S.T., Mee B.J., and Chang B.J. Characterization of the roles of hemolysin and other toxins in enteropathy caused by alpha-hemolytic Escherichia coli linked to human diarrhea. Infect. Immun. 66 (1998) 2040-2051
2. Johnson J.R. Virulence factors in Escherichia coli urinary tract infection. Clin. Microbiol. Rev. 4 (1991) 80-128
3. Felmlee T., Pellett S., and Welch R.A. Nucleotide sequence of an Escherichia coli chromosomal hemolysin. J. Bacteriol. 163 (1985) 94-105
4. Dobrindt U., Janke B., Piechaczek K., Nagy G., Ziebuhr W., Fischer G., Schierhorn A., Hecker M., Blum-Oehler G., and Hacker J. Toxin genes on pathogenicity islands: impact for microbial evolution. Int. J. Med. Microbiol. 290 (2000) 307-311
5. Knapp S., Then I., Wels W., Michel G., Tschape H., Hacker J., and Goebel W. Analysis of the flanking regions from different haemolysin determinants of Escherichia coli. Mol. Gen. Genet. 200 (1985) 385-392
6. Hacker J., Hughes C., Hof H., and Goebel W. Cloned hemolysin genes from Escherichia coli that cause urinary tract infection determine different levels of toxicity in mice. Infect. Immun. 42 (1983) 57-63
7. Welch R.A., and Falkow S. Characterization of Escherichia coli hemolysins conferring quantitative differences in virulence. Infect. Immun. 43 (1984) 156-160
8. Swenson D.L., Bukanov N.O., Berg D.E., and Welch R.A. Two pathogenicity islands in uropathogenic Escherichia coli J96: cosmid cloning and sample sequencing. Infect. Immun. 64 (1996) 3736-3743
9. Blum G., Falbo V., Caprioli A., and Hacker J. Gene clusters encoding the cytotoxic necrotizing factor type 1, Prs- fimbriae and alpha-hemolysin form the pathogenicity island II of the uropathogenic Escherichia coli strain J96. FEMS Microbiol. Lett. 126 (1995) 189-195
10. Dobrindt U., Blum-Oehler G., Nagy G., Schneider G., Johann A., Gottschalk G., and Hacker J. Genetic structure and distribution of four pathogenicity islands (PAI I(536) to PAI IV(536)) of uropathogenic Escherichia coli strain 536. Infect. Immun. 70 (2002) 6365-6372
11. Blum G., Ott M., Lischewski A., Ritter A., Imrich H., Tschape H., and Hacker J. Excision of large DNA regions termed pathogenicity islands from tRNA- specific loci in the chromosome of an Escherichia coli wild-type pathogen. Infect. Immun. 62 (1994) 606-614
12. Datsenko K.A., and Wanner B.L. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 6640-6645
13. Lutz M.B., Kukutsch N., Ogilvie A.L., Rossner S., Koch F., Romani N., and Schuler G. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J. Immunol. Methods. 223 (1999) 77-92
14. Allison C., Emody L., Coleman N., and Hughes C. The role of swarm cell differentiation and multicellular migration in the uropathogenicity of Proteus mirabilis. J. Infect. Dis. 169 (1994) 1155-1158
15. Nagy G., Dobrindt U., Schneider G., Khan A.S., Hacker J., and Emody L. Loss of regulatory protein RfaH attenuates virulence of uropathogenic Escherichia coli. Infect. Immun. 70 (2002) 4406-4413
16. Schneider G., Dobrindt U., Bruggemann H., Nagy G., Janke B., Blum-Oehler G., Buchrieser C., Gottschalk G., Emody L., and Hacker J. The Pathogenicity Island-Associated K15 Capsule Determinant Exhibits a Novel Genetic Structure and Correlates with Virulence in Uropathogenic Escherichia coli Strain 536. Infect. Immun. 72 (2004) 5993-6001
17. Hacker J., Hof H., Emody L., and Goebel W. Influence of cloned Escherichia coli hemolysin genes, S-fimbriae and serum resistance on pathogenicity in different animal models. Microb. Pathog. 1 (1986) 533-547
18. Benz R., Schmid A., Wagner W., and Goebel W. Pore formation by the Escherichia coli hemolysin: evidence for an association-dissociation equilibrium of the pore-forming aggregates. Infect. Immun. 57 (1989) 887-895
19. Osickova A., Osicka R., Maier E., Benz R., and Sebo P. An amphipathic alpha-helix including glutamates 509 and 516 is crucial for membrane translocation of adenylate cyclase toxin and modulates formation and cation selectivity of its membrane channels. J. Biol. Chem. 274 (1999) 37644-37650
20. Reed L.J., and Muench H. A simple method of estimating fifty percent end points. Am. J. Hyg. 27 (1938) 493-497
21. Leeds J.A., and Welch R.A. RfaH enhances elongation of Escherichia coli hlyCABD mRNA. J. Bacteriol. 178 (1996) 1850-1857
22. Leeds J.A., and Welch R.A. Enhancing transcription through the Escherichia coli hemolysin operon, hlyCABD: RfaH and upstream JUMPStart DNA sequences function together via a postinitiation mechanism. J. Bacteriol. 179 (1997) 3519-3527
23. Nieto J.M., Bailey M.J., Hughes C., and Koronakis V. Suppression of transcription polarity in the Escherichia coli haemolysin operon by a short upstream element shared by polysaccharide and DNA transfer determinants. Mol. Microbiol. 19 (1996) 705-713
24. Ludwig A., Schmid A., Benz R., and Goebel W. Mutations affecting pore formation by haemolysin from Escherichia coli. Mol. Gen. Genet. 226 (1991) 198-208
25. Benz R., Dobereiner A., Ludwig A., and Goebel W. Haemolysin of Escherichia coli: comparison of pore-forming properties between chromosome and plasmid-encoded haemolysins. FEMS Microbiol. Immunol. 5 (1992) 55-62
26. Hooper S.D., and Berg O.G. On the nature of gene innovation: duplication patterns in microbial genomes. Mol. Biol. Evol. 20 (2003) 945-954
27. Teichmann S.A., and Babu M.M. Gene regulatory network growth by duplication. Nat. Genet. 36 (2004) 492-496
28. Hooper S.D., and Berg O.G. Duplication is more common among laterally transferred genes than among indigenous genes. Genome Biol. 4 (2003) R48
29. Lynch M., and Conery J.S. The evolutionary fate and consequences of duplicate genes. Science 290 (2000) 1151-1155
30. Papp B., Pal C., and Hurst L.D. Evolution of cis-regulatory elements in duplicated genes of yeast. Trends Genet. 19 (2003) 417-422
31. Zhang Z., Gu J., and Gu X. How much expression divergence after yeast gene duplication could be explained by regulatory motif evolution?. Trends Genet. 20 (2004) 403-407
32. Gu X., Zhang Z., and Huang W. Rapid evolution of expression and regulatory divergences after yeast gene duplication. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 707-712
33. Mekalanos J.J. Duplication and amplification of toxin genes in Vibrio cholerae. Cell. 35 (1983) 253-263
34. Murphy G.L., and Dallas W.S. Analysis of two genes encoding heat-labile toxins and located on a single Ent plasmid from Escherichia coli. Gene 103 (1991) 37-43
35. Dalet K., Weber C., Guillemot L., Njamkepo E., and Guiso N. Characterization of adenylate cyclase-hemolysin gene duplication in a Bordetella pertussis isolate. Infect. Immun. 72 (2004) 4874-4877
36. Zhang X.H., Meaden P.G., and Austin B. Duplication of hemolysin genes in a virulent isolate of Vibrio harveyi. Appl. Environ. Microbiol. 67 (2001) 3161-3167
37. Berger H., Hacker J., Juarez A., Hughes C., and Goebel W. Cloning of the chromosomal determinants encoding hemolysin production and mannose-resistant hemagglutination in Escherichia coli. J. Bacteriol. 152 (1982) 1241-1247
38. Hull R.A., Gill R.E., Hsu P., Minshew B.H., and Falkow S. Construction and expression of recombinant plasmids encoding type 1 or D-mannose-resistant pili from a urinary tract infection Escherichia coli isolate. Infect. Immun. 33 (1981) 933-938
39. Yanisch-Perron C., Vieira J., and Messing J. Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene 33 (1985) 103-119