Tetrandrine concentrations not affecting oxidative phosphorylation protect rat liver mitochondria from oxidative stress

Mitochondrion

Volumn 6, Issue 4, 2006, Pages 176-185

  Fernandes, Maria A S ^a   Custódio, José B A ^a   Santos, Maria S ^a   Moreno, António J M ^a   Vicente, Joaquim A F ^b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Bisbenzylisoquinoline alkaloide; Cancer; Mitochondrial bioenergetics; Permeability transition pore; Tetrandrine

Indexed keywords

ADENOSINE DIPHOSPHATE; ANION CHANNEL; CALCIUM ION; HYDROGEN PEROXIDE; OXYGEN; PHENYLHYDRAZONE DERIVATIVE; POTASSIUM ION; PROTON; SUCCINIC ACID; TETRANDRINE;

ANIMAL CELL; ARTICLE; BIOENERGY; CELL RESPIRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ELECTRON TRANSPORT; LIPID PEROXIDATION; LIVER MITOCHONDRION; LIVER PROTECTION; MALE; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PERMEABILITY; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN;

ANIMALS; ANTIOXIDANTS; BENZYLISOQUINOLINES; CALCIUM; CELL RESPIRATION; HYDROGEN PEROXIDE; LIPID PEROXIDATION; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, LIVER; MITOCHONDRIAL MEMBRANES; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; RATS;

EID: 33748127909     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2006.06.002     Document Type: Article

References (51)

1. Aon M.A., Cortassa S., Marbán E., and O'Rourke B. Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes. J. Biol. Chem. 278 (2003) 44735-44744
2. 2 generation in isolated mitochondria. J. Bioenerg. Biomembr. 34 (2002) 227-233
3. Beavis A.D. Properties of the inner membrane anion channel in intact mitochondria. J. Bioenerg. Biomembr. 24 (1992) 77-90
4. Beavis A.D., Brannan R.D., and Garlid K.D. Swelling and contraction of the mitochondrial matrix. I. Structural interpretation of the relationship between light scattering and matrix volume. J. Biol. Chem. 260 (1985) 13424-13433
5. Broekemeier K.M., Dempsey M.E., and Pfeiffer D.R. Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria. J. Biol. Chem. 264 (1989) 7826-7830
6. +leak and ROS generation: an odd couple. Free Radic. Biol. Med. 38 (2005) 12-23
7. Buege J.A., and Aust S.D. Microsomal lipid peroxidation. Methods Enzymol. 52 (1978) 302-310
8. Cadenas E. Mitochondrial free radical production and cell signalling. Mol. Aspects Med. 25 (2004) 17-26
9. Cadenas E., and Davies K.J. Mitochondrial free radical generation, oxidative stress, and ageing. Free Radic. Biol. Med. 29 (2000) 222-230
10. Cao Z.F. Scavenging effect of tetrandrine of active oxygen radicals. Planta Med. 62 (1996) 413-414
11. Castranova V. Generation of oxygen radicals and mechanisms of injury prevention. Environ. Health Perspect. 102 suppl. 10 (1994) 65-68
12. Chance B., and Williams G.R. The respiratory chain and oxidative phosphorylation. Adv. Enzymol. 17 (1956) 65-134
13. Costantini P., Chernyak B.V., Petronilli V., and Bernardi P. Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two separate sites. J. Biol. Chem. 271 (1996) 6746-6751
14. Ernster L., and Nordenbrand K. Microsomal lipid peroxidation. In: Colowick S.P., and Kaplan N.O. (Eds). Methods in Enzymology (1967), Academic Press, New York 574-580
15. 2+-activated chloride channel in cultured human umbilical vein endothelial cells. Acta Pharmacol. Sim. 25 (2004) 327-333
16. Gazotti P., Malmstron K., and Crompton M.A. Laboratory manual on transport and bioenergetics. In: Carafoli E., and Semenza G. (Eds). Membrane Biochemistry (1979), Springer, New York 62-69
17. Gornall G., Bardawill C.J., and David M.M. Determination of serum proteins by means of the biuret reaction, J. Biol. Chem. 177 (1949) 751-766
18. Halestrap A.P., Woodfield K.Y., and Connern C.P. Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase. J. Biol. Chem. 272 (1997) 3346-3354
19. Hui S.C., Chan T.Y., and Chen Y.Y. Tetrandrine inhibits lipid peroxidation but lacks reactivity towards superoxide anion and hydrogen peroxide. Pharmacol. Toxicol. 78 (1996) 200-201
20. Jang B.-C., Lim K.-J., Paik J.-H., Cho J.-W., Baek W.-K., Suh M.-H., Park J.-B., Kwon T.K., Park J.-W., Kim S.-P., Shin D.-H., Song D.-K., Bae J.-H., Mun K.-C., and Suh S.-I. Tetrandrine-induced apoptosis is mediated by activation of caspases and PKC-δ in U937 cells. Biochem. Pharmacol. 67 (2004) 1819-1829
21. Jezek P., and Hlavatá L. Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism. Intern. J. Biochem. Cell Biol. 37 (2005) 2478-2503
22. Jin Q., Kang C., Soh Y., Sohn N.W., Lee J., Cho Y.H., Baik H.H., and Kang I. Tetrandrine cytotoxicity and its dual effect on oxidative stress-induced apoptosis through modulating cellular redox status in Neuro 2a mouse neuroblastoma cells. Life Sci. 71 (2002) 2053-2066
23. Kamo N., Muratsugu M., Hongoh R., and Kobatake N. Membrane potential of mitochondria measured with an electrode sensitive to tetraphenylphosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state. J. Membr. Biol. 49 (1979) 105-121
24. Koh S.B., Ban J.Y., Lee B.Y., and Seong Y.H. Protective effects of fangchinoline and tetrandrine on hydrogen peroxide-induced oxidative neuronal cell damage in cultured rat cerebellar granule cells. Planta Med. 69 (2003) 506-512
25. Kowaltowski A.J., and Vercesi A.E. Mitochondrial damage induced by conditions of oxidative stress. Free Radic. Biol. Med. 26 (1999) 463-472
26. Kowaltowski A.J., Castilho R.F., and Vercesi A.E. Mitochondrial permeability transition and oxidative stress. FEBS Lett. 495 (2001) 12-15
27. Lee H.-C., and Wei Y.-H. Mitochondrial role in life and death of cell. J. Biomed. Sci. 7 (2000) 2-15
28. Liu Z., Xu Z., Shen W., Li Y., Zhang J., and Ye X. Effect of pharamacologic preconditioning with tetrandrine on subsequent ischemia/reperfusion injury in rat liver. World J. Surg. 28 (2004) 620-624
29. Matsuno T., Orita K., Edashige K., Kobuchi H., Sato E.F., Inouye B., Inoue M., and Utsumi K. Inhibition of active oxygen generation in guinea-pig neutrophils by biscoclaurine alkaloids. Biochem. Pharmacol. 39 (1990) 1255-1259
30. McStay G.P., Clarke S.J., and Halestrap A.P. Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore. Biochem. J. 367 Pt 2 (2002) 541-548
31. Murphy M.P., and Smith R.A.J. Drug delivery to mitochondria: the key to mitochondrial medicine. Adv. Drug Deliv. Rev. 41 (2000) 235-250
32. Oh S.-H., and Lee B.-H. Induction of apoptosis in human hepatoblatoma cells by tetrandrine via caspase-dependent bid cleavage and cytochrome c release. Biochem. Pharmacol. 66 (2003) 725-731
33. O'Rourke B. Pathophysiological and protective roles of mitochondrial ion channels. J. Physiol. 529 (2000) 23-36
34. Pedersen P.L. Mitochondrial events in the life and death of animal cells. A brief overview. J. Bioenerg. Bomembr. 31 (2000) 291-304
35. 2+ concentration associated with glutamate excitotoxicity in cultured rat brain neurons. Neurosc. Lett. 162 (1993) 149-152
36. Ren Z.J., Zeng D.Y., Zhang X.H., Jiao K.R., and Wang H.L. Protective effects of tetrandrine on experimental myocardial ischaemia and reperfusion injury in rabbits. Chin. J. Pharmacol. Toxicol. 9 (1995) 303-304
37. Sassa H., Takaish Y., and Terada H. The triterpene celastrol as a very potent inhibitor of lipid peroxidation in mitochondria. Biochem. Biophys. Res. Commun. 172 (1990) 890-897
38. Sekiya N., Hikiami H., Yokoyama K., Kouta K., Sakakibara I., Shimada Y., and Terasawa K. Inhibitory effects of Stephania tetrandra S. Moore on free radical-induced lysis of rat red blood cells. Biol. Pharm. Bull. 28 (2005) 667-670
39. Seow W.K., Ferrante A., Li S.Y., and Thong Y.H. Antiphagocytic and antioxidant properties of plant alkaloide tetrandrine. Int. Arch. Allergy Appl. Immunol. 85 (1988) 404-409
40. Shen Y.C., Chen C.F., Wang S.Y., and Sung Y.J. Impediment to calcium influx and reactive oxygen production accounts for the inhibition of neutrophil Mac-1 up-regulation and adhesion by tetrandrine. Mol. Pharmacol. 55 (1999) 186-193
41. Shen Y.C., Chen C.F., and Sung Y.J. Tetrandrine ameliorates ischaemia-reperfusion injury of rat myocardium through inhibition of neutrophil priming and activation. Br. J. Pharmacol. 128 (1999) 1593-1601
42. Shen Y.C., Chou C.J., Chiou W.F., and Chen C.F. Anti-inflammatory effects of the partially purified extract of radix Stephaniae tetrandrae: comparative studies of its active principles tetrandrine and fangchinoline on human polymorphonuclear leukocyte functions. Mol. Pharmacol. 60 (2001) 1083-1090
43. Shi X., Mao Y., Saffiotti U., Wang L., Rojanasakul Y., Leonard S.S., and Vallyathan V. Antioxidant activity of tetrandrine and its inhibition of quartz-induced lipid peroxidation. J. Toxicol. Environ. Health 46 (1995) 233-248
44. Vanden Hoek T.L., Becker L.B., Shao Z., Li C., and Schumacker P.T. Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes. J. Biol. Chem. 273 (1998) 18092-18098
45. Vicente J.A.F., Santos M.S., Vercesi A.E., and Madeira V.M.C. Comparative effects of the herbicide dinitro-o-cresol on mitochondrial bioenergetics. Pestic. Sci. 54 (1998) 43-51
46. Wang G., Lemos J.R., and Ladecola C. Herbal alkaloid tetrandrine: from an ion channel blocker to inhibitor of tumour proliferation. Trends Pharmacol. Sci. 25 (2004) 120-123
47. Wu M.N., McKown L.A., and Gopaul V.S. In-vitro metabolism of isotetrandrine, a bisbenzylisoquinoline alkaloid, in rat hepatic S9 fraction by high-performance liquid chromatography-atmospheric pressure ionisation mass spectrometry. J. Pharm. Pharmacol. 56 (2004) 749-755
48. Yan C., Xin-Ming Q., Li-Kun G., Lin-Lin L., Fang-Ping C., Ying X., Xiong-Fei W., Xiang-Hong Li., and Jin R. Tetrandrine-induced apoptosis in rat primary hepatocytes is initiated from mitochondria: Caspases and Endonuclease G (Endo G) pathway. Toxicology 218 (2006) 1-12
49. Ye J., Ding M., Zhang X., Rojanasakul Y., and Shi X. On the role of hydroxyl radical and the effect of tetrandrine on nuclear factor-kappa B activation by phorbol 12-myristate 13-acetate. Ann. Clin. Lab. Sci. 30 (2000) 65-71
50. Yu-Jen C. Potential role of tetrandrine in cancer therapy. Acta Pharmacol. Sin. 23 (2002) 1102-1106
51. 2+ antagonist binding sites are associated with an inner mitochondrial membrane anion channel. Mol. Pharmacol. 38 (1990) 362-369