Cost-effectiveness of neonatal ECG screening for the long QT syndrome

European Heart Journal

Volumn 27, Issue 15, 2006, Pages 1824-1832

  Quaglini, Silvana ^a   Rognoni, Carla ^a   Spazzolini, Carla ^a,b   Priori, Silvia G ^a,c   Mannarino, Savina ^b   Schwartz, Peter J ^a,b  

^a UNIVERSITY OF PAVIA   (Italy)

^b FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^c IRCCS   (Italy)

Author keywords

Cost effectiveness; Long QT syndrome; Neonatal ECG screening; Sudden death; Sudden infant death syndrome

Indexed keywords

ARTICLE; CONGENITAL HEART DISEASE; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DECISION THEORY; DIAGNOSTIC ACCURACY; DIAGNOSTIC ERROR; DIAGNOSTIC TEST; ELECTROCARDIOGRAPHY MONITORING; HEALTH CARE COST; HEALTH PROGRAM; HUMAN; LONG QT SYNDROME; NEWBORN; NEWBORN SCREENING; PRIORITY JOURNAL; PROBABILITY; SENSITIVITY AND SPECIFICITY;

COHORT STUDIES; COST-BENEFIT ANALYSIS; DEATH, SUDDEN, CARDIAC; DECISION TREES; ELECTROCARDIOGRAPHY; HUMANS; INFANT, NEWBORN; LONG QT SYNDROME; MARKOV CHAINS; NEONATAL SCREENING; QUALITY-ADJUSTED LIFE YEARS;

EID: 33748058449     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehl115     Document Type: Article

References (39)

1. Schwartz PJ, Periti M, Malliani A. The long Q-T syndrome. Am Heart J 1975;89:378-390.
2. Moss AJ, Schwartz PJ. 25th Anniversary of the international Long QT Syndrome Registry: an ongoing quest to uncover the secrets of LQTS. Circulation 2005;111:1199-1201.
3. Schwartz PJ, Priori SG, Bloise R, Napolitano C, Ronchetti E, Piccinini A, Goj A, Breithardt G, Schulze-Bahr E, Wedekind H, Nastoli J. Molecular diagnosis in a child with sudden infant death syndrome. Lancet 2001;358:1342-1343.
4. Schwartz PJ, Stramba-Badiale M, Segantini A, Austoni P, Bosi G, Giorgetti R, Grancini F, Marni ED, Perticone F, Rosti D, Salice P. Prolongation of the QT interval and the sudden infant death syndrome. N Engl J Med 1998;338:1709-1714.
5. Schwartz PJ, Priori SG, Dumaine R, Napolitano C, Antzelevitch C, Stramba-Badiale M, Richard TA, Berti MR, Bloise R. A molecular link between the sudden infant death syndrome and the long QT syndrome. N Engl J Med 2000;343:262-267.
6. Tester DJ, Ackerman MJ. Sudden infant death syndrome: how significant are the cardiac channelopathies? Cardiovasc Res 2005;67:388-396.
7. Crotti L, Arnestad M, Insolia R, Pedrazzini M, Ferrandi C, Rognum T, Schwartz PJ. The role of long QT syndrome in sudden infant death syndrome. Eur Heart J 2005;26(Abstract Suppl.):127.
8. Moss AJ, Zareba W, Hall WJ, Schwartz PJ, Crampton RS, Benhorin J, Vincent GM, Locati EH, Priori SG, Napolitano C, Medina A, Zhang L, Robinson JL, Timothy K, Towbin JA, Andrews ML. Effectiveness and limitations of β-blocker therapy in congenital long QT syndrome. Circulation 2000;101:616-623.
9. Priori SG, Napolitano C, Schwartz PJ, Grillo M, Bloise R, Ronchetti E, Moncalvo C, Tulipani C, Veia A, Bottelli G, Nastoli J. Association of long QT syndrome loci and cardiac events among patients treated with beta-blockers. JAMA 2004;292:1341-1344.
10. Schwartz PJ, Priori SG, Cerrone M, Spazzolini C, Odero A, Napolitano C, Bloise R, De Ferrari GM, Klersy C, Moss AJ, Zareba W, Robinson JL, Hall WJ, Brink PA, Toivonen L, Epstein AE, Li C, Hu D. Left cardiac sympathetic denervation in the management of high-risk patients affected by the long QT syndrome. Circulation 2004;109:1826-1833.
11. Lucey JF. Comments on a sudden infant death article in another journal. Pediatrics 1999;103:812.
12. Schwartz PJ, Stramba-Badiale M. Prolonged repolarization and sudden infant death syndrome. In: Zipes DP, Jalife J, eds. Cardiac Electrophysiology From Cell to Bedside. IV ed. Philadelphia: WB Saunders Co.; 2004. p711-719.
13. Schwartz PJ, Garson A Jr, Paul T, Stramba-Badiale M, Vetter VL, Villain E, Wren C. Guidelines for the interpretation of the neonatal electrocardiogram. Eur Heart J 2002;23:1329-1344.
14. Goulene K, Stramba-Badiale M, Crotti L, Priori SG, Salice P, Mannarino S, Rosati E, Schwartz PJ. Neonatal electrocardiographic screening of genetic arrhythmogenic disorders and congenital cardiovascular diseases: prospective data from 31,000 infants. Eur Heart J 2005;26(Abstract Suppl.):214.
15. Crotti L, Stramba-Badiale M, Pedrazzini M, Ferrandi C, Insolia R, Goulene K, Salice P, Mannarino S, Schwartz PJ. Prevalence of the long QT syndrome. Circulation 2005;112(Suppl. II):II-660.
16. Richmond S, Wren C. Early diagnosis of congenital heart disease. Semin Neonatol 2001;6:27-35.
17. Abu-Harb M, Wyllie J, Hey E, Richmond S, Wren C. Presentation of obstructive left heart malformations in infancy. Arch Dis Child 1994;71:F179-F183.
18. Hall DMB. Health for all children. Report of the Third Joint Working Party on Child Health Surveillance. Oxford: Oxford University Press; 1996.
19. Dodge-Khatami A, Mavroudis C, Backer CL. Anomalous origin of the left coronary artery from the pulmonary artery: collective review of surgical therapy. Ann Thorac Surg 2002;74:946-955.
20. Wren C, Richmond S, Donaldson L. Presentation of congenital heart disease in infancy: implications for routine examination. Arch Dis Child 1999;80:F49-F53.
21. Kuehl KS, Loffredo CA, Ferencz C. Failure to diagnose congenital heart disease in infancy. Pediatrics 1999;103:743-747.
22. Gold MR, Siegel JE, Russell LB, Weinstein MC. Cost-Effectiveness in Health and Medicine. New York: Oxford University Press Inc.; 1996.
23. Weinstein MC, Fineberg HV, Elstein AS, Frazier HS, Neuhauser D, Neutra RR, McNeil BJ. Clinical Decision Analysis. Philadelphia: W. B. Saunders; 1980.
24. Sonnenberg FA, Beck JR. Markov models in medical decision making: a practical guide. Med Decis Making 1993;13:322-338.
25. ISTAT. Tavole di Mortalità per la popolazione italiana, a cura di M. Marsili e M. Battaglini, collana 'Informazioni', n. 9, 2006.
26. Priori SG, Schwartz PJ, Napolitano C, Bloise R, Ronchetti E, Grillo M, Vicentini A, Spazzolini C, Nastoli J, Bottelli G, Folli R, Cappelletti D. Risk stratification in the long-QT syndrome. N Engl J Med 2003;348:1866-1874.
27. Laupacis A, Feeny D, Detsky AS, Tugwell PX. How attractive does a new technology have to be to warrant adoption and utilization? Tentative guidelines for using clinical and economic evaluations. CMAJ 1992;146:473-481.
28. Neumann PJ, Sandberg EA, Bell CM, Stone PW, Chapman RH. Are pharmaceuticals cost-effective? A review of the evidence. Health Aff 2000;19:92-109.
29. Towse A, Pritchard C, Devlin N (eds). Cost-Effectiveness Thresholds: Economic and Ethical Issues. UK:King's Fund and Office of Health Economics; 2002.
30. Zupancic JA, Triedman JK, Alexander M, Walsh EP, Richardson DK, Berul CI. Cost-effectiveness and implications of newborn screening for prolongation of QT interval for the prevention of sudden infant death syndrome. J Pediatr 2000;136:481-489.
31. McBride KL, Marengo L, Canfield M, Langlois P, Fixler D, Belmont JW. Epidemiology of noncomplex left ventricular outflow tract obstruction malformations (aortic valve stenosis, coarctation of the aorta, hypoplastic left heart syndrome) in Texas, 1999-2001. Birth Defects Res A Clin Mol Teratol 2005;73:555-561.
32. Rosen K, Mart C, Myers J. Anomalous left coronary artery from the pulmonary artery: surgical perspective. www.emedicine.com/ped/topic2899.htm (2002).
33. Garson A Jr, Dick M II, Fournier A, Gillette PC, Hamilton R, Kugler JD, van Hare GF III, Vetter V, Vick GW III. The long QT syndrome in children: an international study of 287 patients. Circulation 1993;87:1866-1872.
34. Richmond S, Reay G, Abu Harb M. Routine pulse oximetry in the asymptomatic newborn. Arch Dis Child 2002;87:F83-F88.
35. Schwartz PJ, Priori SG, Napolitano C. How really rare are rare diseases? The intriguing case of independent compound mutations in the long QT syndrome. J Cardiovasc Electrophysiol 2003;14:1120-1121.
36. Zareba W, Moss AJ, Schwartz PJ, Vincent GM, Robinson JL, Priori SG, Benhorin J, Locati EH, Towbin JA, Keating MT, Lehmann MH, Hall WJ, for the International Long-QT Syndrome Registry Research Group. Influence of genotype on the clinical course of the long-QT syndrome. N Engl J Med 1998;339:960-965.
37. Schwartz PJ, Priori SG, Spazzolini C, Moss AJ, Vincent GM, Napolitano C, Denjoy I, Guicheney P, Breithardt G, Keating MT, Towbin JA, Beggs AH, Brink P, Wilde AAM, Toivonen L, Zareba W, Robinson JL, Timothy KW, Corfield V, Wattanasirichaigoon D, Corbett C, Haverkamp W, Schulze-Bahr E, Lehmann MH, Schwartz K, Coumel P, Bloise R. Genotype-phenotype correlation in the long QT syndrome. Gene-specific triggers for life-threatening arrhythmias. Circulation 2001;103:89-95.
38. Zareba W, Moss AJ, Daubert JP, Hall WJ, Robinson JL, Andrews M. Implantable cardioverter defibrillator in high-risk long QT syndrome patients. J Cardiovasc Electrophysiol 2003;14:337-341.
39. Crotti L, Spazzolini C, De Ferrari GM, Landolina M, Bloise R, Napolitano C, Monnig G, Brugada P, Toivonen L, Hohnloser SH, Tukkie R, Wilde AA, Priori SG, Schwartz PJ. Is the implantable defibrillator appropriately used in the long QT syndrome? Data from the European Registry. Heart Rhythm 2004;1(suppl.):582.