The Role of Inhaled Nitric Oxide and Heliox in the Management of Acute Respiratory Failure

Respiratory Care Clinics of North America

Volumn 12, Issue 3, 2006, Pages 489-500

  Gentile, Michael A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOCAINE; DAPSONE; DIPYRIDAMOLE; ENDOTHELIN 1; HELIOX; METOCLOPRAMIDE; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXYGEN; PRILOCAINE; SILDENAFIL;

ACUTE RESPIRATORY FAILURE; ADULT RESPIRATORY DISTRESS SYNDROME; AEROSOL; ARTIFICIAL VENTILATION; CLINICAL TRIAL; DISEASE EXACERBATION; DRUG DOSE REGIMEN; DRUG INDICATION; DRUG POTENTIATION; HUMAN; LUNG SHUNTING; METHEMOGLOBINEMIA; OXYGEN TENSION; PULMONARY HYPERTENSION; REVIEW; THROMBOCYTE AGGREGATION INHIBITION;

ADMINISTRATION, INHALATION; ANOXIA; FREE RADICAL SCAVENGERS; HELIUM; HUMANS; NITRIC OXIDE; OXYGEN; RESPIRATION, ARTIFICIAL; RESPIRATORY DISTRESS SYNDROME, ADULT; TREATMENT OUTCOME;

EID: 33748037041     PISSN: 10785337     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rcc.2006.06.006     Document Type: Review

References (52)

1. Moncada S., Palmer R.M., and Higgs E.A. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 43 (1991) 109-142
2. Brett S.J., Hansell D.M., and Evans T.W. Clinical correlates in acute lung injury: response to inhaled nitric oxide. Chest 114 (1998) 1397-1404
3. Palmer R.M., Ferrige A.G., and Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327 (1987) 524-526
4. Koshland D.E. The molecule of the year. Science 258 (1992) 1861
5. Bian K., and Murad F. Nitric oxide biogeneration, regulation, and relevance to human diseases. Front Biosci 8 (2003) 264-278
6. Miller C.C., and Miller J.W. Pulmonary vascular smooth muscle regulation: the role of inhaled nitric oxide gas. Respir Care 37 (1992) 1175-1185
7. Kaisers U., Busch T., Deja M., et al. Selective pulmonary vasodilation in acute respiratory distress syndrome. Crit Care Med 31 (2003) S337-S342
8. Villar J., Blazquez M.A., Lubillo S., et al. Pulmonary hypertension in acute respiratory failure. Crit Care Med 17 (1989) 523-526
9. Zapol W.M., and Snider M.T. Pulmonary hypertension in severe acute respiratory failure. N Engl J Med 296 (1977) 476-480
10. Rossaint R., Falke K.J., Lopez F., et al. Inhaled nitric oxide for the adult respiratory distress syndrome. N Engl J Med 328 (1993) 399-405
11. Dobyns E.L., Anas N.G., Fortenberry J.D., et al. Interactive effects of high-frequency oscillatory ventilation and inhaled nitric oxide in acute hypoxemic respiratory failure in pediatrics. Crit Care Med 30 (2002) 2425-2429
12. Kinsella J.P., and Abman S.H. High-frequency oscillatory ventilation augments the response to inhaled nitric oxide in persistent pulmonary hypertension of the newborn: Nitric Oxide Study Group. Chest 114 (1998) 100S
13. Mehta S., MacDonald R., Hallett D.C., et al. Acute oxygenation response to inhaled nitric oxide when combined with high-frequency oscillatory ventilation in adults with acute respiratory distress syndrome. Crit Care Med 31 (2003) 383-389
14. Puybasset L., Rouby J.J., Mourgeon E., et al. Factors influencing cardiopulmonary effects of inhaled nitric oxide in acute respiratory failure. Am J Respir Crit Care Med 152 (1995) 318-328
15. Bigatello L.M., Hurford W.E., Kacmarek R.M., et al. Prolonged inhalation of low concentrations of nitric oxide in patients with severe adult respiratory distress syndrome. Effects on pulmonary hemodynamics and oxygenation. Anesthesiology 80 (1994) 761-770
16. Dellinger R.P., Zimmerman J.L., and Taylor R.W. Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: results of a randomized, phase II trial. Crit Care Med 26 (1998) 15-23
17. Taylor R.W., Zimmerman J.L., and Dellinger R.P. Low-dose inhaled nitric oxide in patients with acute lung injury: a randomized controlled trial. JAMA 291 (2004) 1603-1609
18. Young J.D., Brampton W.J., Knighton J.D., et al. Inhaled nitric oxide in acute respiratory failure in adults. Br J Anaesth 73 (1994) 499-502
19. Gerlach H., Pappert D., Lewandowski K., et al. Long-term inhalation with evaluated low doses of nitric oxide for selective improvement of oxygenation in patients with adult respiratory distress syndrome. Intensive Care Med 19 (1993) 443-449
20. Michael J.R., Barton R.G., Saffle J.R., et al. Inhaled nitric oxide versus conventional therapy: effect on oxygenation in ARDS. Am J Respir Crit Care Med 157 (1998) 1372-1380
21. Gerlach H., Keh D., Semmerow A., et al. Dose-response characteristics during long-term inhalation of nitric oxide in patients with severe acute respiratory distress syndrome: a prospective, randomized, controlled study. Am J Respir Crit Care Med 167 (2003) 1008-1015
22. McIntyre R.C., Moore F.A., Moore E.E., et al. Inhaled nitric oxide variably improves oxygenation and pulmonary hypertension in patients with acute respiratory distress syndrome. J Trauma 39 (1995) 418-425
23. Papazian L., Bregeon F., Gaillat F., et al. Respective and combined effects of prone position and inhaled nitric oxide in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 157 (1998) 580-585
24. Krafft P.P., Fridich R.D., and Fitzgerald D. Effectiveness of nitric oxide inhalation in septic ARDS. Chest 109 (1996) 486-493
25. Abman S.H., Griebel J.L., Parker D.K., et al. Acute effects of inhaled nitric oxide in children with severe hypoxemic respiratory failure. J Pediatr 124 (1994) 881-888
26. Okamoto K., Hamaguchi M., Kukita I., et al. Efficacy of inhaled nitric oxide in children with ARDS. Chest 114 (1998) 827-833
27. Day R.W., Allen E.M., and Witte M.K. A randomized, controlled study of the 1-hour and 24-hour effects of inhaled nitric oxide therapy in children with acute hypoxemic respiratory failure. Chest 112 (1997) 1324-1331
28. Goldman A.P., Tasker R.C., Hosiasson S., et al. Early response to inhaled nitric oxide and its relationship to outcome in children with severe hypoxemic respiratory failure. Chest 112 (1997) 752-758
29. Fioretto J.R., de Moraes M.A., Bonatto R.C., et al. Acute and sustained effects of early administration of inhaled nitric oxide to children with acute respiratory distress syndrome. Pediatr Crit Care Med 5 (2004) 469-474
30. Mehta S., MacDonald R., Hullett D.C., et al. Acute oxygenation response to inhaled nitric oxide when combined with high-frequency oscillatory ventilation in adults with acute respiratory distress syndrome. Crit Care Med 31 2 (2003) 383-389
31. Baldauf M., Silver P., and Sagy M. Evaluating the validity of responsiveness to inhaled nitric oxide in pediatric patients with ARDS: an analytic tool. Chest 119 (2001) 1166-1172
32. Clark R.H., Kueser T.J., Walker M.W., et al. Low-dose nitric oxide therapy for persistent pulmonary hypertension of the newborn. Clinical Inhaled Nitric Oxide Research Group. N Engl J Med 342 (2000) 469-474
33. Davidson D., Barefield E.S., Kattwinkel J., et al. Inhaled nitric oxide for the early treatment of persistent pulmonary hypertension of the term newborn: a randomized, double-masked, placebo-controlled, dose-response, multicenter study. The I-NO/PPHN Study Group. Pediatrics 101 (1998) 325-334
34. Roberts Jr. J.D., Fineman J.R., Morin III F.C., et al. Inhaled nitric oxide and persistent pulmonary hypertension of the newborn. The Inhaled Nitric Oxide Study Group. N Engl J Med 336 (1997) 605-610
35. The Neonatal Inhaled Nitric Oxide Study. Inhaled nitric oxide in full-term and nearly full-term infants with hypoxic respiratory failure. N Engl J Med 336 (1997) 597-604
36. Atz A.M., Lefler A.K., Fairbrother D.L., et al. Sildenafil augments the effect of inhaled nitric oxide for postoperative pulmonary hypertensive crises. J Thorac Cardiovasc Surg 124 (2002) 628-629
37. Saygili A., Canter B., Iriz E., et al. Use of sildenafil with inhaled nitric oxide in the management of severe pulmonary hypertension. J Cardiothorac Vasc Anesth 18 (2004) 775-776
38. Weinberger B., Laskin D.L., Heck D.E., et al. The toxicology of inhaled nitric oxide. Toxicol Sci 59 (2001) 5-16
39. Barach A.L. The use of helium in the treatment of asthma and obstructive lesions in the larynx and trachea. Ann Intern Med 9 (1935) 739-765
40. Barnett T.B. Effects of helium and oxygen mixtures on pulmonary mechanics during airway constriction. J Appl Physiol 22 (1967) 707-713
41. Kemper K.J., Ritz R.H., Benson M.S., et al. Helium-oxygen mixture in the treatment of postextubation stridor in pediatric trauma patients. Crit Care Med 19 (1991) 356-359
42. Gluck E.H., Onoranto D.J., and Castriotta R. Helium-oxygen mixtures in intubated patients with status asthmaticus and respiratory acidosis. Chest 98 (1990) 693-698
43. Rodeberg D.A., Easter A.J., Washam M.A., et al. Use of a helium-oxygen mixture in the treatment of postextubation stridor in pediatric patients with burns. J Burn Care Rehabil 16 (1995) 476-480
44. Douglas J.D., and Robinson C. Heliox treatment for spinal decompression sickness following air dives. Undersea Biomed Res 15 (1988) 315-319
45. Winters J.W., Willing M.A., and Sanfilippo D. Heliox improves ventilation during high-frequency oscillatory ventilation in pediatric patients. Pediatr Crit Care Med 1 (2000) 33-37
46. Fleming M.D., Weigelt J.A., Brewer V., et al. Effect of helium and oxygen on airflow in a narrowed airway. Arch Surg 127 (1992) 956-959
47. Gupta V.K., and Cheifetz I.M. Heliox administration in the pediatric intensive care unit: an evidence-based review. Pediatr Crit Care Med 6 (2005) 204-211
48. Gupta V.K., Grayck E.N., and Cheifetz I.M. Heliox administration during high-frequency jet ventilation augments carbon dioxide clearance. Respir Care 49 (2004) 1038-1044
49. Katz A.L., Gentile M.A., Craig D.M., et al. Heliox does not affect gas exchange during high-frequency oscillatory ventilation if tidal volume is held constant. Crit Care Med 31 (2003) 2006-2009
50. Anderson M., Svartengren M., Bylin G., et al. Deposition in asthmatics of particles inhaled in air or in helium-oxygen. Am Rev Respir Dis 147 (1993) 524-528
51. Kim I.K., Phrampus E., Venkataraman S., et al. Helium/oxygen-driven albuterol nebulization in the treatment of children with moderate to severe asthma exacerbations: a randomized, controlled trial. Pediatrics 116 (2005) 1127-1133
52. Oppenheim-Eden A., Cohen Y., Weissman C., et al. The effect of helium on ventilator performance: study of five ventilators and a bedside Pitot tube spirometer. Chest 120 (2001) 582-588