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Volumn 66, Issue 15, 2006, Pages 7453-7459

Misexpression of full-length HMGA2 induces benign mesenchymal tumors in mice

Author keywords

[No Author keywords available]

Indexed keywords

HIGH MOBILITY GROUP A2 PROTEIN;

EID: 33747888858     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-0931     Document Type: Article
Times cited : (77)

References (38)
  • 1
    • 0032088139 scopus 로고    scopus 로고
    • HMGI family proteins: Architectural transcription factors in mammalian development and cancer
    • Zhou X, Chada K. HMGI family proteins: architectural transcription factors in mammalian development and cancer. Keio J Med 1998;47:73-7.
    • (1998) Keio J Med , vol.47 , pp. 73-77
    • Zhou, X.1    Chada, K.2
  • 2
    • 0035962921 scopus 로고    scopus 로고
    • HMGI/Y proteins: Flexible regulators of transcription and chromatin structure
    • Reeves R, Beckerbauer L. HMGI/Y proteins: flexible regulators of transcription and chromatin structure. Biochim Biophys Acta 2001;1519:13-29.
    • (2001) Biochim Biophys Acta , vol.1519 , pp. 13-29
    • Reeves, R.1    Beckerbauer, L.2
  • 3
    • 10744227944 scopus 로고    scopus 로고
    • Transcriptional activation of the cyclin A gene by the architectural transcription factor HMGA2
    • Tessari MA, Gostissa M, Altamura S, et al. Transcriptional activation of the cyclin A gene by the architectural transcription factor HMGA2. Mol Cell Biol 2003;23:9104-16.
    • (2003) Mol Cell Biol , vol.23 , pp. 9104-9116
    • Tessari, M.A.1    Gostissa, M.2    Altamura, S.3
  • 4
    • 0345531054 scopus 로고    scopus 로고
    • High mobility group A2 protein and its derivatives bind a specific region of the promoter of DNA repair gene ERCC1 and modulate its activity
    • Borrmann L, Schwanbeck R, Heyduk T, et al. High mobility group A2 protein and its derivatives bind a specific region of the promoter of DNA repair gene ERCC1 and modulate its activity. Nucleic Acids Res 2003;31:6841-51.
    • (2003) Nucleic Acids Res , vol.31 , pp. 6841-6851
    • Borrmann, L.1    Schwanbeck, R.2    Heyduk, T.3
  • 5
    • 0029779677 scopus 로고    scopus 로고
    • HMGI-C expression patterns in human tissues. Implications for the genesis of frequent mesenchymal tumors
    • Rogalla P, Drechsler K, Frey G, et al. HMGI-C expression patterns in human tissues. Implications for the genesis of frequent mesenchymal tumors. Am J Pathol 1996;149:775-9.
    • (1996) Am J Pathol , vol.149 , pp. 775-779
    • Rogalla, P.1    Drechsler, K.2    Frey, G.3
  • 6
    • 0026338691 scopus 로고
    • cDNA cloning of the HMGI-C phosphoprotein, a nuclear protein associated with neoplastic and undifferentiated phenotypes
    • Manfioletti G, Giancotti V, Bandiera A, et al. cDNA cloning of the HMGI-C phosphoprotein, a nuclear protein associated with neoplastic and undifferentiated phenotypes. Nucleic Acids Res 1991;19:6793-7.
    • (1991) Nucleic Acids Res , vol.19 , pp. 6793-6797
    • Manfioletti, G.1    Giancotti, V.2    Bandiera, A.3
  • 7
    • 0029094755 scopus 로고
    • Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-C
    • Zhou X, Benson KF, Ashar HR, Chada K. Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-C. Nature 1995;376:771-4.
    • (1995) Nature , vol.376 , pp. 771-774
    • Zhou, X.1    Benson, K.F.2    Ashar, H.R.3    Chada, K.4
  • 8
    • 0034069653 scopus 로고    scopus 로고
    • In vivo modulation of Hmgic reduces obesity
    • Anand A, Chada K. In vivo modulation of Hmgic reduces obesity. Nat Genet 2000;34:377-80.
    • (2000) Nat Genet , vol.34 , pp. 377-380
    • Anand, A.1    Chada, K.2
  • 10
    • 0029018303 scopus 로고
    • Disruption of the architectural factor HMGI-C: DNA-binding at hook motifs fused in lipomas to distinct transcriptional regulatory domains
    • Ashar HR, Fejzo MS, Tkachenko A, et al. Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains. Cell 1995;82:57-65.
    • (1995) Cell , vol.82 , pp. 57-65
    • Ashar, H.R.1    Fejzo, M.S.2    Tkachenko, A.3
  • 11
    • 9044233250 scopus 로고    scopus 로고
    • HMGI-C rearrangements as the molecular basis for the majority of pulmonary chondroid hamartomas: A survey of 30 tumors
    • Kazmierczak B, Rosigkeit J, Wanschura S, et al. HMGI-C rearrangements as the molecular basis for the majority of pulmonary chondroid hamartomas: a survey of 30 tumors. Oncogene 1996;12:515-21.
    • (1996) Oncogene , vol.12 , pp. 515-521
    • Kazmierczak, B.1    Rosigkeit, J.2    Wanschura, S.3
  • 12
    • 0030752387 scopus 로고    scopus 로고
    • HMGIC expressed in a uterine leiomyoma with a deletion of the long arm of chromosome 7 along with a 12q14-15 rearrangement but not in tumors showing del(7) as the sole cytogenetic abnormality
    • Hennig Y, Rogalla P, Wanschura S, et al. HMGIC expressed in a uterine leiomyoma with a deletion of the long arm of chromosome 7 along with a 12q14-15 rearrangement but not in tumors showing del(7) as the sole cytogenetic abnormality. Cancer Genet Cytogenet 1997;96:129-33.
    • (1997) Cancer Genet Cytogenet , vol.96 , pp. 129-133
    • Hennig, Y.1    Rogalla, P.2    Wanschura, S.3
  • 13
    • 0029919738 scopus 로고    scopus 로고
    • A fibroadenoma with a t(4;12) (q27;q15) affecting the HMGI-C gene, a member of the high mobility group protein gene family
    • Staats B, Bonk U, Wanschura S, et al. A fibroadenoma with a t(4;12) (q27;q15) affecting the HMGI-C gene, a member of the high mobility group protein gene family. Breast Cancer Res Treat 1996;38:299-303.
    • (1996) Breast Cancer Res Treat , vol.38 , pp. 299-303
    • Staats, B.1    Bonk, U.2    Wanschura, S.3
  • 15
    • 0031013993 scopus 로고    scopus 로고
    • Expression of reciprocal hybrid transcripts of HMGIC and FHIT in a pleomorphic adenoma of the parotid gland
    • Geurts JM, Schoenmakers EF, Roijer E, Stenman G, Van de Ven WJ. Expression of reciprocal hybrid transcripts of HMGIC and FHIT in a pleomorphic adenoma of the parotid gland. Cancer Res 1997;57:13-7.
    • (1997) Cancer Res , vol.57 , pp. 13-17
    • Geurts, J.M.1    Schoenmakers, E.F.2    Roijer, E.3    Stenman, G.4    Van De Ven, W.J.5
  • 16
    • 0030990036 scopus 로고    scopus 로고
    • Molecular characterization of a complex chromosomal rearrangement in a pleomorphic salivary gland adenoma involving the 3′-UTR of HMGIC
    • Geurts JM, Schoenmakers EF, Van de Ven WJ. Molecular characterization of a complex chromosomal rearrangement in a pleomorphic salivary gland adenoma involving the 3′-UTR of HMGIC. Cancer Genet Cytogenet 1997;95:198-205.
    • (1997) Cancer Genet Cytogenet , vol.95 , pp. 198-205
    • Geurts, J.M.1    Schoenmakers, E.F.2    Van De Ven, W.J.3
  • 17
    • 0028785795 scopus 로고
    • A hamartoma of the breast with an aberration of 12q mapped to the MAK region by fluorescence in situ hybridization
    • Rohen C, Caselitz J, Stern C, et al. A hamartoma of the breast with an aberration of 12q mapped to the MAK region by fluorescence in situ hybridization. Cancer Genet Cytogenet 1995;84:82-4.
    • (1995) Cancer Genet Cytogenet , vol.84 , pp. 82-84
    • Rohen, C.1    Caselitz, J.2    Stern, C.3
  • 19
    • 0031969943 scopus 로고    scopus 로고
    • Amplification and expression of the HMGIC gene in a benign endometrial polyp
    • Dal Cin P, Wanschura S, Kazmierczak B, et al. Amplification and expression of the HMGIC gene in a benign endometrial polyp. Genes Chromosomes Cancer 1998;22:95-9.
    • (1998) Genes Chromosomes Cancer , vol.22 , pp. 95-99
    • Dal Cin, P.1    Wanschura, S.2    Kazmierczak, B.3
  • 20
    • 0030975144 scopus 로고    scopus 로고
    • Misexpression of disrupted HMGI architectural factors activates alternative pathways of tumorigenesis
    • Tkachenko A, Ashar HR, Meloni AM, Sandberg AA, Chada KK. Misexpression of disrupted HMGI architectural factors activates alternative pathways of tumorigenesis. Cancer Res 1997;57:2276-80.
    • (1997) Cancer Res , vol.57 , pp. 2276-2280
    • Tkachenko, A.1    Ashar, H.R.2    Meloni, A.M.3    Sandberg, A.A.4    Chada, K.K.5
  • 21
    • 0030479029 scopus 로고    scopus 로고
    • Fusion transcripts between the HMGIC gene and RTVL-H-related sequences in mesenchymal tumors without cytogenetic aberrations
    • Kazmierczak B, Pohnke Y, Bullerdiek J. Fusion transcripts between the HMGIC gene and RTVL-H-related sequences in mesenchymal tumors without cytogenetic aberrations. Genomics 1996;38:223-6.
    • (1996) Genomics , vol.38 , pp. 223-226
    • Kazmierczak, B.1    Pohnke, Y.2    Bullerdiek, J.3
  • 22
    • 0033215388 scopus 로고    scopus 로고
    • The expression of a truncated HMGI-C gene induces gigantism associated with lipomatosis
    • Battista S, Fidanza V, Fedele M, et al. The expression of a truncated HMGI-C gene induces gigantism associated with lipomatosis. Cancer Res 1999;59:4793-7.
    • (1999) Cancer Res , vol.59 , pp. 4793-4797
    • Battista, S.1    Fidanza, V.2    Fedele, M.3
  • 23
    • 0032581753 scopus 로고    scopus 로고
    • Truncated and chimeric HMGI-C genes induce neoplastic transformation of NIH3T3 murine fibroblasts
    • Fedele M, Berlingieri MT, Scala S, et al. Truncated and chimeric HMGI-C genes induce neoplastic transformation of NIH3T3 murine fibroblasts. Oncogene 1998;17:413-8.
    • (1998) Oncogene , vol.17 , pp. 413-418
    • Fedele, M.1    Berlingieri, M.T.2    Scala, S.3
  • 24
  • 25
    • 0001768750 scopus 로고    scopus 로고
    • Translocation breakpoints upstream of the HMGIC gene in uterine leiomyomata suggest deregulation of this gene by a mechanism different from that in lipomas
    • Schoenberg Fejzo M, Ashar HR, Krauter KS, et al. Translocation breakpoints upstream of the HMGIC gene in uterine leiomyomata suggest deregulation of this gene by a mechanism different from that in lipomas. Genes Chromosomes Cancer 1996;17:1-6.
    • (1996) Genes Chromosomes Cancer , vol.17 , pp. 1-6
    • Schoenberg Fejzo, M.1    Ashar, H.R.2    Krauter, K.S.3
  • 26
    • 0025637601 scopus 로고
    • A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo
    • Ross SR, Graves KA, Greenstein A, et al. A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo. Proc Natl Acad Sci U S A 1990;87:9590-4.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 9590-9594
    • Ross, S.R.1    Graves, K.A.2    Greenstein, A.3
  • 27
    • 0032936408 scopus 로고    scopus 로고
    • Dominant effects of RET receptor misexpression and ligand-independent RET signaling on ureteric bud development
    • Srinivas S, Wu Z, Chen CM, D'Agati V, Costantini F. Dominant effects of RET receptor misexpression and ligand-independent RET signaling on ureteric bud development. Development 1999;126:1375-86.
    • (1999) Development , vol.126 , pp. 1375-1386
    • Srinivas, S.1    Wu, Z.2    Chen, C.M.3    D'Agati, V.4    Costantini, F.5
  • 29
    • 20744439516 scopus 로고    scopus 로고
    • The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it
    • Hay ED. The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it. Dev Dyn 2005;233:706-20.
    • (2005) Dev Dyn , vol.233 , pp. 706-720
    • Hay, E.D.1
  • 31
    • 0033770092 scopus 로고    scopus 로고
    • The melanocortin 5 receptor is expressed in human sebaceous glands and rat preputial cells
    • Thiboutot D, Sivarajah A, Gilliland K, Cong Z, Clawson G. The melanocortin 5 receptor is expressed in human sebaceous glands and rat preputial cells. J Invest Dermatol 2000;115:614-9.
    • (2000) J Invest Dermatol , vol.115 , pp. 614-619
    • Thiboutot, D.1    Sivarajah, A.2    Gilliland, K.3    Cong, Z.4    Clawson, G.5
  • 33
    • 0034640377 scopus 로고    scopus 로고
    • Transgenic mice expressing a truncated form of the high mobility group I-C protein develop adiposity and an abnormally high prevalence of lipomas
    • Arlotta P, Tai AK, Manfioletti G, Clifford C, Jay G, Ono SJ. Transgenic mice expressing a truncated form of the high mobility group I-C protein develop adiposity and an abnormally high prevalence of lipomas. J Biol Chem 2000;275:14394-400.
    • (2000) J Biol Chem , vol.275 , pp. 14394-14400
    • Arlotta, P.1    Tai, A.K.2    Manfioletti, G.3    Clifford, C.4    Jay, G.5    Ono, S.J.6
  • 34
    • 85047700396 scopus 로고    scopus 로고
    • Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas
    • Fedele M, Battista S, Kenyon L, et al. Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas. Oncogene 2002;21:3190-8.
    • (2002) Oncogene , vol.21 , pp. 3190-3198
    • Fedele, M.1    Battista, S.2    Kenyon, L.3
  • 35
    • 17144468766 scopus 로고    scopus 로고
    • HMGI-C and HMGI(Y) immunoreactivity correlates with cytogenetic abnormalities in lipomas, pulmonary chondroid hamartomas, endometrial polyps, and uterine leiomyomas and is compatible with rearrangement of the HMGI-C and HMGI(Y) genes
    • Tallini G, Vanni R, Manfioletti G, et al. HMGI-C and HMGI(Y) immunoreactivity correlates with cytogenetic abnormalities in lipomas, pulmonary chondroid hamartomas, endometrial polyps, and uterine leiomyomas and is compatible with rearrangement of the HMGI-C and HMGI(Y) genes. Lab Invest 2000;80:359-69.
    • (2000) Lab Invest , vol.80 , pp. 359-369
    • Tallini, G.1    Vanni, R.2    Manfioletti, G.3
  • 37
    • 9244227134 scopus 로고    scopus 로고
    • Stromal fibroblasts in cancer initiation and progression
    • Bhowmick NA, Neilson EG, Moses HL. Stromal fibroblasts in cancer initiation and progression. Nature 2004;432:332-7.
    • (2004) Nature , vol.432 , pp. 332-337
    • Bhowmick, N.A.1    Neilson, E.G.2    Moses, H.L.3
  • 38
    • 17044434576 scopus 로고    scopus 로고
    • Fusion oncogenes and tumor type specificity - Insights from salivary gland tumors
    • Stenman G. Fusion oncogenes and tumor type specificity-insights from salivary gland tumors. Semin Cancer Biol 2005;15:224-35.
    • (2005) Semin Cancer Biol , vol.15 , pp. 224-235
    • Stenman, G.1


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