Specific deletion of CMF1 nuclear localization domain causes incomplete cell cycle withdrawal and impaired differentiation in avian skeletal myoblasts

Experimental Cell Research

Volumn 312, Issue 16, 2006, Pages 3000-3014

  Dees, Ellen ^a   Robertson, J Brian ^a   Zhu, Tianli ^a   Bader, David ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

CMF1; LEK protein; LEK1; Myocyte differentiation

Indexed keywords

ANIMAL CELL; ARTICLE; BIRD; CELL CYCLE; CELL DIFFERENTIATION; CELL LINE; CELL NUCLEUS; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CHICKEN; CHROMATIN; CONTROLLED STUDY; CYTOPLASM; EMBRYO; GENE DELETION; GENETIC TRANSFECTION; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR TRANSPORT; MITOSIS; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SYNCYTIUM; WILD TYPE;

AVES;

EID: 33747878235     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2006.06.027     Document Type: Article

References (50)

1. Dees E., Pabon-Pena L.M., Goodwin R., and Bader D. Characterization of CMF1 protein in avian skeletal muscle. Dev. Dyn. 219 (2000) 169-181
2. Wei Y., Bader D., and Litvin J. Identification of a novel cardiac-specific transcript critical for cardiac myocyte differentiation. Development 122 (1996) 2779-2789
3. Zhou X., Wang R., Fan L., Li Y., Ma L., Yang Z., Yu W., Jing N., and Zhu X. Mitosin/CENP-F as a negative regulator of activating transcription factor-4. J. Biol. Chem. 280 (2005) 13973-13977
4. Clark G.M., Allred D.C., Hilsenbeck S.G., Chamness G.C., Osborne C.K., Jones D., and Lee W.H. Mitosin (a new proliferation marker) correlates with clinical outcome in node-negative breast cancer. Cancer Res. 57 (1997) 5505-5508
5. Konstantinidou A.E., Korkolopoulou P., Kavantzas N., Mahera H., Thymara I., Kotsiakis X., Perdiki M., Patsouris E., and Davaris P. Mitosin, a novel marker of cell proliferation and early recurrence in intracranial meningiomas. Histol. Histopathol. 18 (2003) 67-74
6. Wang J., Buchholz T.A., Middleton L.P., Allred D.C., Tucker S.L., Kuerer H.M., Esteva F.J., Hortobagyi G.N., and Sahin A.A. Assessment of histologic features and expression of biomarkers in predicting pathologic response to anthracycline-based neoadjuvant chemotherapy in patients with breast carcinoma. Cancer 94 (2002) 3107-3114
7. Zhu X., Chang K., He D., Mancini M.A., Brinkley W.R., and Lee W. The C terminus of mitosin is essential for its nuclear localization, centromere/kinetochore targeting, and dimerization. J. Biol. Chem. 270 (1995) 19545-19550
8. Zhu X., Ding L., and Pei G. Carboxyl terminus of mitosin is sufficient to confer spindle pole localization. J. Cell. Biochem. 66 (1997) 441-449
9. Zhu X., Mancini M.A., Chang K., Liu C., Chen C., Shan B., Jones D., Yang-Feng T.L., and Lee W. Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression. Mol. Cell. Biol. 15 (1995) 5017-5029
10. Soukoulis V., Reddy S., Pooley R.D., Feng Y., Walsh C.A., and Bader D.M. Cytoplasmic LEK1 is a regulator of microtubule function through its interaction with the LIS1 pathway. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 8549-8554
11. Goodwin R.L., Pabon-Pena L.M., Foster G.C., and Bader D. The cloning and analysis of LEK1 identifies variations in the LEK/centromere protein F/mitosin gene family. J. Biol. Chem. 274 (1999) 18597-18604
12. Dees E., Robertson J.B., Ashe M., Pabon-Pena L.M., Bader D., and Goodwin R.L. LEK1 protein expression in normal and dysregulated cardiomyocyte mitosis. Anat. Rec. A Discov. Mol. Cell Evol. Biol. 286A (2005) 823-832
13. Ashe M., Pabon-Pena L., Dees E., Price K.L., and Bader D. LEK1 is a potential inhibitor of pocket protein-mediated cellular processes. J. Biol. Chem. 279 (2004) 664-676
14. Papadimou E., Menard C., Grey C., and Puceat M. Interplay between the retinoblastoma protein and LEK1 specifies stem cells toward the cardiac lineage. EMBO J. 24 (2005) 1750-1761
15. Yang Z.Y., Guo J., Li N., Qian M., Wang S.N., and Zhu X.L. Mitosin/CENP-F is a conserved kinetochore protein subjected to cytoplasmic dynein-mediated poleward transport. Cell Res. 13 (2003) 275-283
16. Pabon-Pena L.M., Goodwin R.L., Cise L.J., and Bader D. Analysis of CMF1 reveals a bone morphogenetic protein-independent component of the cardiomyogenic pathway. J. Biol. Chem. 275 (2000) 21453-21459
17. Bader D., Masaki T., and Fischman D.A. Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro. J. Cell Biol. 95 (1982) 763-770
18. Harlow E., and Lane D. Antibodies: A Laboratory Manual (1988), Cold Spring Harbor Laboratory 479-504
19. Knight R.F., Bader D.M., and Backstrom J.R. Membrane topology of Bves/Pop1A, a cell adhesion molecule that displays dynamic changes in cellular distribution during development. J. Biol. Chem. 278 (2003) 32872-32879
20. Wada A.M., Reese D.E., and Bader D.M. Bves: prototype of a new class of cell adhesion molecules expressed during coronary artery development. Development 128 (2001) 2085-2093
21. Glimm H., Oh I.H., and Eaves C.J. Human hematopoietic stem cells stimulated to proliferate in vitro lose engraftment potential during their S/G(2)/M transit and do not reenter G(0). Blood 96 (2000) 4185-4193
22. Gothot A., Pyatt R., McMahel J., Rice S., and Srour E.F. Functional heterogeneity of human CD34(+) cells isolated in subcompartments of the G0/G1 phase of the cell cycle. Blood 90 (1997) 4384-4393
23. Janumyan Y.M., Sansam C.G., Chattopadhyay A., Cheng N., Soucie E.L., Penn L.Z., Andrews D., Knudson C.M., and Yang E. Bcl-xL/Bcl-2 coordinately regulates apoptosis, cell cycle arrest and cell cycle entry. EMBO J. 22 (2003) 5459-5470
24. Darzynkiewicz Z., Kapuscinski J., Traganos F., and Crissman H.A. Application of pyronin Y(G) in cytochemistry of nucleic acids. Cytometry 8 (1987) 138-145
25. Shapiro H.M. Flow cytometric estimation of DNA and RNA content in intact cells stained with Hoechst 33342 and pyronin Y. Cytometry 2 (1981) 143-150
26. Redkar A., deRiel J.K., Xu Y.S., Montgomery M., Patwardhan V., and Litvin J. Characterization of cardiac muscle factor 1 sequence motifs: retinoblastoma protein binding and nuclear localization. Gene 282 (2002) 53-64
27. Antin P.B., Karp G.C., and Ordahl C.P. Transgene expression in the QM myogenic cell line. Dev. Biol. 143 (1991) 122-129
28. Antin P.B., and Ordahl C.P. Isolation and characterization of an avian myogenic cell line. Dev. Biol. 143 (1991) 111-121
29. Dabiri G.A., Turnacioglu K.K., Sanger J.M., and Sanger J.W. Myofibrillogenesis visualized in living embryonic cardiomyocytes. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 9493-9498
30. Pizon V., Iakovenko A., Van Der Ven P.F., Kelly R., Fatu C., Furst D.O., Karsenti E., and Gautel M. Transient association of titin and myosin with microtubules in nascent myofibrils directed by the MURF2 RING-finger protein. J. Cell Sci. 115 (2002) 4469-4482
31. Cheong H.T., Park T.M., Ikeda K., and Takahashi Y. Cell cycle analysis of bovine cultured somatic cells by flow cytometry. Jpn. J. Vet. Res. 51 (2003) 95-103
32. Andres V., and Walsh K. Myogenin expression, cell cycle withdrawal, and phenotypic differentiation are temporally separable events that precede cell fusion upon myogenesis. J. Cell Biol. 132 (1996) 657-666
33. Chang B.D., Broude E.V., Fang J., Kalinichenko T.V., Abdryashitov R., Poole J.C., and Roninson I.B. p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells. Oncogene 19 (2000) 2165-2170
34. Chang B.D., Xuan Y., Broude E.V., Zhu H., Schott B., Fang J., and Roninson I.B. Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs. Oncogene 18 (1999) 4808-4818
35. Engel F.B., Hauck L., Boehm M., Nabel E.G., Dietz R., and von Harsdorf R. p21(CIP1) controls proliferating cell nuclear antigen level in adult cardiomyocytes. Mol. Cell. Biol. 23 (2003) 555-565
36. Kelman Z., and Hurwitz J. Protein-PCNA interactions: a DNA-scanning mechanism?. Trends Biochem. Sci. 23 (1998) 236-238
37. Kelman Z., and O'Donnell M. Structural and functional similarities of prokaryotic and eukaryotic DNA polymerase sliding clamps. Nucleic Acids Res. 23 (1995) 3613-3620
38. Efimov V.P. Roles of NUDE and NUDF proteins of Aspergillus nidulans: insights from intracellular localization and overexpression effects. Mol. Biol. Cell 14 (2003) 871-888
39. Efimov V.P., and Morris N.R. The LIS1-related NUDF protein of Aspergillus nidulans interacts with the coiled-coil domain of the NUDE/RO11 protein. J. Cell Biol. 150 (2000) 681-688
40. Xiang X., Osmani A.H., Osmani S.A., Xin M., and Morris N.R. NudF, a nuclear migration gene in Aspergillus nidulans, is similar to the human LIS-1 gene required for neuronal migration. Mol. Biol. Cell 6 (1995) 297-310
41. Xiang X., Zuo W., Efimov V.P., and Morris N.R. Isolation of a new set of Aspergillus nidulans mutants defective in nuclear migration. Curr. Genet. 35 (1999) 626-630
42. Asada M., Ohmi K., Delia D., Enosawa S., Suzuki S., Yuo A., Suzuki H., and Mizutani S. Brap2 functions as a cytoplasmic retention protein for p21 during monocyte differentiation. Mol. Cell. Biol. 24 (2004) 8236-8243
43. Li S., Ku C.Y., Farmer A.A., Cong Y.S., Chen C.F., and Lee W.H. Identification of a novel cytoplasmic protein that specifically binds to nuclear localization signal motifs. J. Biol. Chem. 273 (1998) 6183-6189
44. Burton P.B., Raff M.C., Kerr P., Yacoub M.H., and Barton P.J. An intrinsic timer that controls cell-cycle withdrawal in cultured cardiac myocytes. Dev. Biol. 216 (1999) 659-670
45. Chen C.Y., and Schwartz R.J. Identification of novel DNA binding targets and regulatory domains of a murine tinman homeodomain factor, nkx-2.5. J. Biol. Chem. 270 (1995) 15628-15633
46. Lints T.J., Parsons L.M., Hartley L., Lyons I., and Harvey R.P. Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development 119 (1993) 419-431
47. Olson E.N., and Srivastava D. Molecular pathways controlling heart development. Science 272 (1996) 671-676
48. Schultheiss T.M., Burch J.B., and Lassar A.B. A role for bone morphogenetic proteins in the induction of cardiac myogenesis. Genes Dev. 11 (1997) 451-462
49. Srivastava D., Cserjesi P., and Olson E.N. New subclass of bHLH proteins required for cardiac morphogenesis. Science 270 (1995) 1995-1999
50. Zhang H., and Bradley A. Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development. Development 122 (1996) 2977-2986