Mitosin (a new proliferation marker) correlates with clinical outcome in node-negative breast cancer

Cancer Research

Volumn 57, Issue 24, 1997, Pages 5505-5508

  Clark, Gary M ^a   Allred, D Craig ^b   Hilsenbeck, Susan G ^a   Chamness, Gary C ^a   Osborne, C Kent ^a   Jones, Diane ^a   Lee, Wen Hwa ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS PHOSPHOPROTEIN; MITOSIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 14C10; PHOSPHOPROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CELL CYCLE S PHASE; CELL PROLIFERATION; DIAGNOSTIC VALUE; FEMALE; FLOW CYTOMETRY; FOLLOW UP; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANIMALS; ANTIBODIES, MONOCLONAL; BREAST NEOPLASMS; CELL DIVISION; CHROMOSOMAL PROTEINS, NON-HISTONE; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPH NODES; MICE; MICE, INBRED BALB C; MICROFILAMENT PROTEINS; MULTIVARIATE ANALYSIS; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PILOT PROJECTS; PROGNOSIS; TISSUE DISTRIBUTION; TUMOR MARKERS, BIOLOGICAL;

EID: 0031467820     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Zhu, X., Mancini, M. A., Chang, C-H., Liu, C-Y., Chen, C-F., Shan, B., Jones, D., Yang-Feng, T. L., and Lee, W. H. Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression. Mol. Cell. Biol., 15: 5017-5029, 1995.
2. Zhu, X., Chang, K., He, D., Mancini, M. A., Brinkley, W. R., and Lee, W. H. The C-terminus of mitosin is essential for its nuclear localization, centromere/kinetochore targeting, and dimerization. J. Biol. Chem., 270: 19545-19550, 1995.
3. Oi, V. T., and Herzenberg, L. A. Immunoglobin-producing hybrid cell lines. In: B. B Mishell and S. M. Shiigi (ed.s.). Selected Methods in Cellular Immunology, pp. 351-372. San Francisco: W. H. Freeman and Co., 1980.
4. Clark, G. M., Dressler, L. G., Owens, M. A., Pounds, G., Oldaker, T., and McGuire, W. L. Prediction of relapse or survival in patients with node-negative breast cancer by DNA flow cytometry. N. Engl. J. Med., 320: 627-633, 1989.
5. Allred, D. C., Clark, G. M., Tandon, A. K., and McGuire, W. L. Immunohistochemistry on histological sections from small (50 mg) samples of pulverized breast cancer. J. Histotechnol., 16: 117-120, 1993.
6. McGuire, W. L., De La Garza, M., and Chamness, G. C. Evaluation of estrogen receptor assays in human breast cancer tissue. Cancer Res., 37: 637-639, 1977.
7. Powell, B., Garola, R. E., Chamness, G. C., and McGuire, W. L. Measurement of progesterone receptor in human breast cancer biopsies. Cancer Res., 39: 1678-1679, 1979.
8. Dressler, L. G., Seamer, L. C., Owens, M. A., Clark, G. M., and McGuire, W. L. DNA flow cytometry and prognostic factors in 1331 frozen breast cancer specimens. Cancer (Phila.), 61: 420-427, 1988.
9. Wenger, C. R., Beardslee, S., Owens, M. A., Pounds, G., Oldaker, T., Pandian, M. R., Harrington, D., Clark, G. M., and McGuire, W. L. DNA ploidy, S-phase, and steroid receptors in more than 127,000 breast cancer patients. Breast Cancer Res. Treat., 28: 9-20, 1993.
10. Clark, G. M., Mathieu, M-C., Owens, M. A., Dressler, L. G., Eudey, L., Tormey, D. C., Osbome, C. K., Gilchrist, K. W., Mansour, E. G., Abeloff, M. D., and McGuire, W. L. Prognostic significance of S-phase fraction in good-risk, node-negative breast cancer patients. J. Clin. Oncol., 10: 428-432, 1992.
11. Kaplan, E. L. and Meier, P. L. Nonparametric estimation from incomplete observations. Am. Stat. Assoc., 53: 457-481, 1958.
12. Cox, D., and Oakes, D. Analysis of Survival Data, pp. 104-107. New York: Chapman and Hall, 1984.
13. Cox, D. R. Regression models and life-tables. J. R. Stat. Soc. B, 34: 187-200, 1972.
14. Hedley, D. W., Clark, G. M., Comelisse, C. J., Killander, D., Kute, T., and Merkel, D. Consensus review of the clinical utility of DNA cytometry in carcinoma of the breast. Cytometry. 14: 482-485, 1993.
15. Clark, G. M. Prognostic and predictive factors. In: J. R. Harris, M. E. Lippman, M. Morrow, and S. Hellman (eds.). Diseases of the Breast, pp. 199-215. Philadelphia: Lippincott-Raven, 1996.
16. Hilsenbeck, S. G., and Clark, G. M. Practical p-value adjustment for optimally selected cutpoints. Stat. Med., 15: 103-112, 1996.
17. Gasparini, G., Boracchi, P., Verderio, P., and Bevilacqua, P. Cell kinetics in human breast cancer. Comparison between the prognostic value of the cytofluorimetric S-phase fraction and that of the antibodies to Ki-67 and PCNA antigens detected by immunocytochemistry. Int. J. Cancer, 57: 822-829, 1994.
18. Brown, R. W., Allred, D. C., Clark, G. M., Osborne, C. K., and Hilsenbeck, S. G. Prognostic value of Ki-67 compared to S-phase fraction in axillary node-negative breast cancer. Clin. Cancer Res., 2: 585-592, 1996.
19. Siitonen, S. M., Kallioniemi, O-P., and Isola, J. J. Proliferating cell nuclear antigen immunohistochemistry using monoclonal antibody 19A2 and a new antigen retrieval technique has prognostic impact in archival paraffin-embedded node-negative breast cancer. Am. J. Pathol., 142: 1081-1089, 1993.