Temporary elevation of the intraocular pressure by cauterization of vortex and episcleral veins in rats causes functional deficits in the retina and optic nerve

Experimental Eye Research

Volumn 77, Issue 1, 2003, Pages 27-33

  Grozdanic, Sinisa D ^a   Betts, Daniel M ^a   Sakaguchi, Donald S ^a   Kwon, Young H ^b   Kardon, Randy H ^b   Sonea, Ioana M ^a  

^a IOWA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

Electroretinogram; Glaucoma; Optic nerve; Pupils; Rat; Tonometry

Indexed keywords

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAUTERIZATION; CONTROLLED STUDY; CORRELATION ANALYSIS; ELECTRORETINOGRAM; EVALUATION; EYE INJURY; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; NONHUMAN; OCULAR BLOOD VESSEL; OPTIC NERVE; PRIORITY JOURNAL; PUPIL REFLEX; PUPILLOMETER; RAT; RETINA; VISION;

EID: 0038434061     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4835(03)00089-7     Document Type: Article

References (17)

1. Bayer A.U., Danias J., Brodie S., Maag K.P., Chen B., Shen F., Podos S.M., Mittag T.W. Electroretinographic abnormalities in a rat glaucoma model with chronic elevated intraocular pressure. Exp. Eye. Res. 72:(6):2001;667-677.
2. Bayer A.U., Neuhardt T., May A.C., Martus P., Maag K.P., Brodie S., Lutjen-Drecoll E., Podos S.M., Mittag T. Retinal morphology and ERG response in the DBA/2NNia mouse model of angle-closure glaucoma. Invest. Ophthalmol. Vis. Sci. 42:(6):2001;1258-1265.
3. Chauhan B.C., Pan J., Archibald M.L., LeVatte T.L., Kelly M.E., Tremblay F. Effect of intraocular pressure on optic disc topography, electroretinography, and axonal loss in a chronic pressure-induced rat model of optic nerve damage. Invest. Ophthalmol. Vis. Sci. 43:(9):2002;2969-2976.
4. Farkas R.H., Grosskreutz C.L. Apoptosis, neuroprotection, and retinal ganglion cell death: an overview. Int. Ophthalmol. Clin. 41:2001;111-130.
5. Garcia-Valenzuela E., Shareef S., Walsh J., Sharma S.C. Programmed cell death of retinal ganglion cells during experimental glaucoma. Exp. Eye Res. 61:(1):1995;33-44.
6. Goldblum D., Mittag T. Prospects for relevant glaucoma models with retinal ganglion cell damage in the rodent eye. Vis. Res. 42:2002;471-478.
7. Grozdanic, S., Sakaguchi, D.S., Kwon, Y.H., Kardon, R.H., Sonea, I.M., 2003. Characterization of the pupil light reflex, electroretinogram and tonometric parameters in healthy rat eyes. Curr. Eye Res., accepted for publication.
8. McKinnon S.J., Pease M.E., WoldeMussie E., Zack D.J., Quigley H.A., Kerrigan-Baumrind L.A., Mitchell R.S., Ruiz G. Comparison of three models of rat glaucoma caused by chronic intraocular pressure elevation. Invest. Ophthalmol. Vis. Sci. 40:(Supplement):1999;S787. Abstract.
9. Mittag T.W., Danias J., Pohorenec G., Yuan H.M., Burakgazi E., Chalmers-Redman R., Podos S.M., Tatton W.G. Retinal damage after 3 to 4 months of elevated intraocular pressure in a rat glaucoma model. Invest. Ophthalmol. Vis. Sci. 41:(11):2000;3451-3459.
10. Moore C.G., Milne S.T., Morrison J.C. Noninvasive measurement of rat intraocular pressure with the Tono-Pen. Invest. Ophthalmol. Vis. Sci. 34:(2):1993;363-369.
11. Morrison J.C., Moore C.G., Deppmeier L.M., Gold B.G., Meshul C.K., Johnson E.C. A rat model of chronic pressure-induced optic nerve damage. Exp. Eye Res. 64:(1):1997;85-96.
12. Osborne N.O., Melena J., Chidlow G., Wood J.P. A hypothesis to explain ganglion cell death caused by vascular insults at the optic nerve head: possible implication for the treatment of glaucoma. Br. J. Ophthalmol. 85:2001;1252-1259.
13. Quigley H.A. Number of people with glaucoma worldwide. Br. J. Ophthalmol. 80:1996;389.
14. Quigley H.A. Neuronal death in glaucoma. Prog. Retin. Eye Res. 18:1999;39-57.
15. Quigley H.A., Nickell R.W., Kerrigan L.A., et al. Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis. Invest. Ophthalmol. Vis. Sci. 36:1995;774-786.
16. Shareef S.R., Garcia-Valenzuela E., Salierno A., Walsh J., Sharma S.C. Chronic ocular hypertension following episcleral venous occlusion in rats. Exp. Eye Res. 61:1995;379-382.
17. Ueda J., Sawaguchi S., Hanyu T., Yaoeda K., Fukuchi T., Abe H., Ozawa H. Experimental glaucoma model in the rat induced by laser trabecular photocoagulation after an intracameral injection of India ink. Jpn. J. Ophthalmol. 42:(5):1998;337-344.