Cumulative mutations affecting sterol biosynthesis in the yeast Saccharomyces cerevisiae result in synthetic lethality that is suppressed by alterations in sphingolipid profiles

Genetics

Volumn 173, Issue 4, 2006, Pages 1893-1908

  Valachovic, Martin ^a,e   Bareither, Bart M ^a   Bhuiyan, M Shah Alam ^a   Eckstein, James ^b   Barbuch, Robert ^b   Balderes, Dina ^c   Wilcox, Lisa ^c   Sturley, Stephen L ^c   Dickson, Robert C ^d   Bard, Martin ^a  

^a INDIANA UNIVERSITY   (United States)

^b ELI LILLY AND COMPANY   (United States)

^c NewYork Presbyterian Hospital   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

^e INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

[No Author keywords available]

Indexed keywords

APYRASE; SPHINGOLIPID; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ECM22; TRANSCRIPTION FACTOR HAP1; TRANSCRIPTION FACTOR UPC2; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; GENE CONTROL; GENE DELETION; GENE DISRUPTION; GENE MUTATION; GENE REPRESSION; GENETIC ANALYSIS; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; STEROL SYNTHESIS; TRANSPOSON; YEAST;

CANDIDA ALBICANS; GENE DELETION; GENES, FUNGAL; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SPHINGOLIPIDS; STEROLS;

CANDIDA ALBICANS; SACCHAROMYCES CEREVISIAE;

EID: 33747860537     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.105.053025     Document Type: Article

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