Neuroleptic drugs in the human brain: Clinical impact of persistence and region-specific distribution

European Archives of Psychiatry and Clinical Neuroscience

Volumn 256, Issue 5, 2006, Pages 274-280

  Kornhuber, Johannes ^a   Wiltfang, Jens ^a   Riederer, Peter ^b   Bleich, Stefan ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Haloperidol; Human; Levomepromazine; Neuroleptic drug; Pharmacokinetics; Postmortem brain; Region specific distribution

Indexed keywords

HALOPERIDOL; LEVOMEPROMAZINE; NEUROLEPTIC AGENT; NORLEVOMEPROMAZINE; UNCLASSIFIED DRUG;

ADULT; AGED; AUTOPSY; BASAL GANGLION; BRAIN CORTEX; BRAIN TISSUE; CEREBELLUM; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; DRUG EFFECT; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; FEMALE; HUMAN; HUMAN TISSUE; LIMBIC SYSTEM; MALE; NEUROTOXICITY; PRIORITY JOURNAL; REVIEW; SCHIZOPHRENIA; THALAMUS;

AGED; AGED, 80 AND OVER; ANTIPSYCHOTIC AGENTS; BLOOD-BRAIN BARRIER; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION; FEMALE; HALF-LIFE; HALOPERIDOL; HUMANS; MALE; METHOTRIMEPRAZINE; MIDDLE AGED; POSTMORTEM CHANGES; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 33747831757     PISSN: 09401334     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00406-006-0661-7     Document Type: Review

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