Clozapine and some other antipsychotic drugs may preferentially block the same subset of GABAA receptors

Neurochemical Research

Volumn 22, Issue 2, 1997, Pages 151-162

  Squires, Richard F ^a   Saederup, Else ^a  

^a NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

Author keywords

Antipsychotic drugs; Benzodiazepine binding sites; Clozapine; DMCM; GABAA receptor multiplicity; Ro 5 4864; Triazolam

Indexed keywords

2 BROMO 4 (4 CHLOROPHENYL) 9 METHYL 6H THIENO[3,2 F][1,2,4]TRIAZOLO[4,3 A][1,4]DIAZEPINE; 2 PHENYL 5H PYRAZOLO[4,3 C]QUINOLIN 3 ONE; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 4 ETHYL 6,7 DIMETHOXY BETA CARBOLINE 3 CARBOXYLIC ACID METHYL ESTER; 4' CHLORODIAZEPAM; 7 HYDROXYCHLORPROMAZINE; AMOXAPINE; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE; BRETAZENIL; BROTIZOLAM; CLONAZEPAM; CLOZAPINE; FLUMAZENIL; INDALPINE; LOXAPINE; METRALINDOLE; NALOXONE; NEUROLEPTIC AGENT; NITRAFUDAM; QUAZEPAM; STRYCHNINE; THEOPHYLLINE; TRIAZOLAM; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZOLPIDEM; ZOPICLONE; ZOTEPINE;

ARTICLE; BINDING SITE; CONCENTRATION RESPONSE; DRUG RECEPTOR BINDING; FOREBRAIN; LIGAND BINDING; PRIORITY JOURNAL; PSYCHOPHARMACOLOGY; PSYCHOSIS;

ANIMALS; ANTIDEPRESSIVE AGENTS; ANTIPSYCHOTIC AGENTS; BENZODIAZEPINES; BENZODIAZEPINONES; BICYCLO COMPOUNDS, HETEROCYCLIC; CARBOLINES; CLOZAPINE; DRUG SYNERGISM; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; NALOXONE; PROSENCEPHALON; RATS; RECEPTORS, GABA;

STRYCHNOS TOXIFERA;

EID: 0031027977     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/a:1027359422433     Document Type: Article

References (16)

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