Characterization of an LQT5-related mutation in KCNE1, Y81C: Implications for a role of KCNE1 cytoplasmic domain in IKs channel function

Heart Rhythm

Volumn 3, Issue 9, 2006, Pages 1031-1040

  Wu, Dong Mei ^a   Lai, Ling Ping ^b   Zhang, Mei ^a   Wang, Hui Liang ^a   Jiang, Min ^a   Liu, Xian Sheng ^a   Tseng, Gea Ny ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Long QT syndrome; Mutagenesis; Slow delayed rectifier K channel; Voltage clamp

Indexed keywords

POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNE1; POTASSIUM CHANNEL KCNQ1; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

AB INITIO CALCULATION; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOCHEMISTRY; CELL STRAIN COS7; CELL SURFACE; CELLULAR DISTRIBUTION; CHANNEL GATING; CONTROLLED STUDY; CYTOPLASM; DRUG SENSITIVITY; ELECTROPHYSIOLOGY; GENE ACTIVATION; GENE EXPRESSION; GENE MUTATION; IMMUNOCYTOCHEMISTRY; INTRACELLULAR TRANSPORT; LONG QT SYNDROME; NONHUMAN; OOCYTE; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; PROTEIN TRANSPORT; STRUCTURE ANALYSIS; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOPLASM; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; KCNQ POTASSIUM CHANNELS; LONG QT SYNDROME; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, VOLTAGE-GATED;

EID: 33747831107     PISSN: 15475271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hrthm.2006.05.022     Document Type: Article

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