Optimal genetic manipulations in batch bioreactor control

Automatica

Volumn 42, Issue 10, 2006, Pages 1723-1733

  Gadkar, Kapil G ^a   Mahadevan, Radhakrishnan ^b   Doyle III, Francis J ^a,c  

^a University of California   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adaptive algorithm; Batch control; Biotechnology; End point control; Fermentation processes; Optimal control; Scheduling algorithms

Indexed keywords

ADAPTIVE ALGORITHMS; BIOREACTORS; BIOTECHNOLOGY; FERMENTATION; MATHEMATICAL MODELS; OPTIMIZATION; SCHEDULING;

BATCH CONTROL; END POINT CONTROL; FERMENTATION PROCESSES; SCHEDULING ALGORITHMS;

OPTIMAL CONTROL SYSTEMS;

EID: 33747768919     PISSN: 00051098     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.automatica.2006.05.004     Document Type: Article

References (26)

1. Arpornwichanop A., Kittisupakorn A., and Mujtaba I.M. On-line dynamic optimization and control strategy for improving the performance of batch reactors. Chemical Engineering Process 44 (2005) 101-114
2. Åström K.J., and Wittenmark B. Adaptive control. 2nd ed. (1989), Addison-Wesley, Reading, MA
3. Atkinson D.E. Cellular energy metabolism and its regulation (1977), Academic Press, New York 88-100
4. Bailey J.E. Towards a science of metabolic engineering. Science 252 (1991) 1668-1675
5. Bonvin D. Optimal operation of batch reactors-A personal view. Journal of Processing Control 8 (1998) 268-355
6. Burgard A.P., Pharkya P., and Maranas C. OptKnock: A bilevel programming framework for identifying gene knockout strategies for microbial strain optimization. Biotechnology and Bioengineering 84 (2003) 647-657
7. Covert M.W., and Palsson B.O. Transcriptional regulation in constraints-based metabolic models of Escherichia coli. Journal of Biology and Chemistry 277 (2002) 28058-28064
8. Edwards J.S., Covert M.W., and Palsson B.O. Metabolic modelling of microbes: The flux-balance approach. Environment Microbiology 4 (2002) 133-140
9. Gadkar K.G., Doyle III F.J., Edwards J.S., and Mahadevan R. Estimating optimal profiles of genetic alterations using constraint-based models. Biotechnology and Bioengineering 89 (2005) 243-251
10. Herring C.D., Glasner J.D., and Blattner F.R. Gene replacement without selection: Regulated suppression of amber mutations in Escherichia coli. Gene 331 (2003) 153-163
11. Kim J.Y.H., and Cha H.J. Down-regulation of acetate pathway through antisense strategy in Escherichia coli: Improved foreign protein production. Biotechnology and Bioengineering 83 (2003) 841-853
12. Lee S.Y., and Papoutsakis E.T. The challenges and promise of metabolic engineering. Metabolic engineering (1999), Marcel Dekker, New York 1-12
13. Leonardo M.R., Dailly Y., and Clark D.P. Role of NAD in regulating the adhE gene of Escherichia coli. Journal of Bacteriology 178 20 (1996) 6013-6018
14. Lima R.M., Francois G., Srinivasan B., and Salcedo R.L. Dynamic optimization of batch emulsion polymerization using MSIMPSA, a simulated-annealing-based algorithm. Industrial Engineering Chemistry Research 43 (2004) 7796-7806
15. Loeblein C., Perkins J.D., Srinivasan B., and Bonvin D. Economic performance analysis in the design of on-line batch optimization systems. Journal of Processing Control 9 (1999) 61-78
16. Mahadevan R., Edwards J.S., and Doyle III F.J. Dynamic flux balance analysis of diauxic growth in E. coli. Biophysics Journal 83 (2002) 1331-1340
17. Nielsen J. Metabolic engineering: Techniques for analysis of genetic manipulations. Biotechnology and Bioengineering 58 (1998) 125-132
18. Neilsen J. Metabolic engineering. Applied Microbiology and Biotechnology 55 (2001) 263-283
19. Price N.D., Reed J.L., and Palsson B.O. Genome-scale models of microbial cells: Evaluating the consequences of constraints. Nature Reviews Microbiology 2 (2004) 886-897
20. Rouf S.A., Moo-Young M., Scharer J.M., and Douglas P.L. Single versus multiple bioreactor scale-up: Economy for high-value products. Biochemical Engineering 6 (2000) 25-31
21. Samsatli N.J., and Shah N. An optimization based design procedure for biochemical processes. 2. Detailed scheduling. Food and Bioproducts Processing 74 (1996) 232-242
22. Schilling C.H., Edwards J.S., Letscher D., and Palsson B.O. Combining pathway analysis with flux balance analysis for the comprehensive study of metabolic systems. Biotechnology and Bioengineering 71 4 (2000) 286-306
23. Sheela B.V. An optimized step-size random search (OSSRS). Computer Methods in Applied Mechanical Engineering 19 (1979) 99-106
24. Shimizu H. Metabolic engineering-integrating methodologies of molecular breeding and bioprocess systems engineering. Journal of Bioscience and Bioengineering 94 (2002) 563-573
25. Underwood S.A., Zhou S., Causey T.B., Yomano L.P., Shanmugam K.T., and Ingram L.O. Genetic changes to optimize carbon partitioning between ethanol and biosynthesis in ethanologenic Escherichia coli. Applied Environmental Microbiology 68 (2002) 6263-6272
26. Yang Y.T., San K.Y., and Bennett G.N. Redistribution of metabolic fluxes in Escherichia coli with fermentative lactate dehydrogenase overexpression and deletion. Metabolic Engineering 1 (1999) 141-152