Structural basis for D-amino acid transamination by the pyridoxal 5′-phosphate-dependent catalytic antibody 15A9

Journal of Biological Chemistry

Volumn 281, Issue 33, 2006, Pages 23969-23977

  Golinelli Pimpaneau, Béatrice ^a   Lüthi, Christine ^b   Christen, Philipp ^b  

^a LABORATOIRE D ENZYMOLOGIE ET BIOCHIMIE STRUCTURALES   (France)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BIOCHEMISTRY; CRYSTAL STRUCTURE; ENZYME KINETICS; MOLECULAR BIOLOGY; WATER;

ANTIBODY 15A9; ENANTIOMERIC SELECTIVITY; MOBILE TYR-H100B; TRANSAMINATION;

AMINO ACIDS;

5' PHOSPHOPYRIDOXYL(N ALPHA (PYRIDOXAL 5 PHOSPHATE)) N EPSILON ACETYL LYSINE; ALANINE; ALANINE ALDIMINE; ALANINE DERIVATIVE; AMINOTRANSFERASE; CATALYTIC ANTIBODY; CATALYTIC ANTIBODY 15A9; DEXTRO AMINO ACID; HAPTEN; LYSINE; N ACETYL LYSINE; PYRIDOXAL 5 PHOSPHATE; PYRIDOXAL 5 PHOSPHATE DEPENDENT AMINOTRANSFERASE; TYROSINE; UNCLASSIFIED DRUG;

ANTIBODY STRUCTURE; ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; COVALENT BOND; CRYSTAL STRUCTURE; ENANTIOSELECTIVITY; ENZYME ACTIVE SITE; ENZYME BINDING; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTON TRANSPORT; TRANSAMINATION;

ALANINE TRANSAMINASE; ANTIBODIES, CATALYTIC; ANTIBODIES, MONOCLONAL; BINDING SITES, ANTIBODY; CATALYSIS; IMINES; PYRIDOXAL PHOSPHATE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33747725286     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M602184200     Document Type: Article

References (33)

1. Schultz, P. G., and Lerner, R. A. (1995) Science 269, 1835-1842
2. Golinelli-Pimpaneau, B. (2000) Curr. Opin. Struct. Biol. 10, 697-708
3. Golinelli-Pimpaneau, B. (2002) J. Immunol. Methods 269, 157-171
4. Golinelli-Pimpaneau, B., Goncalves, O., Dintinger, T., Blanchard, D., Knossow, M., and Tellier, C. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 9892-9895
5. Debler, E. W., Ito, S., Seebeck, F. P., Heine, A., Hilvert, D., and Wilson, I. A. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 4984-4989
6. Barbas, C. F., III, Heine, A., Zhong, G., Hoffmann, T., Gramatikova, S., Bjornestedt, R., List, B., Anderson, J., Stura, E. A., Wilson, I. A., and Lerner, R. A. (1997) Science 278, 2085-2092
7. Hilvert, D. (2000) Annu. Rev. Biochem. 69, 751-793
8. Hsieh-Wilson, L. C., Schultz, P. G., and Stevens, R. C. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 5363-5367
9. Gramatikova, S. I., and Christen, P. (1996) J. Biol. Chem. 271, 30583-30586
10. Gramatikova, S. I., and Christen, P. (1997) J. Biol. Chem. 272, 9779-9784
11. Mouratou, B., Gramatikova, S. I., Kunz, B., and Christen, P. (2000) Mol. Immunol. 37, 633-640
12. Gramatikova, S., Mouratou, B., Stetefeld, J., Mehta, P. K., and Christen, P. (2002) J. Immunol. Methods 269, 99-110
13. Morino, Y., Osman, A. M., and Okamoto, M. (1974) J. Biol. Chem. 249, 6684-6692
14. Golinelli-Pimpaneau, B. (2005) Acta Crystallogr. Sect. D 61, 472-476
15. Mouratou, B., and Stetefeld, J. (2004) Biochemistry 43, 6612-6619
16. Otwinovsky, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-325
17. Sheldrick, G. M., and Schneider, T. R. (1997) Methods Enzymol. 277, 319-343
18. Navaza, J. (1994) Acta Crystallogr. Sect. A 50, 157-163
19. Banfield, M. J. (1996) Acta Crystallogr. Sect. D 52, 1107-1113
20. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard. (1991) Acta Crystallogr. Sect. A 47, 110-119
21. Adams, P. D., Pannu, N. S., Read, R. J., and Brunger, A. T. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 5018-5023
22. Kirsch, J. F., Eichele, G., Ford, G. C., Vincent, M. G., Jansonius, J. N., Gehring, H., and Christen, P. (1984) J. Mol. Biol. 174, 497-525
23. Jansonius, J. N. (1998) Curr. Opin. Struct. Biol. 8, 759-769
24. α-5′-phosphopyridoxyl-L-lysine. M.D. thesis, University of Zürich
25. Malashkevich, V. N., Toney, M. D., and Jansonius, J. N. (1993) Biochemistry 32, 13451-13462
26. Peisach, D., Chipman, D. M., Van Ophem, P. W., Manning, J. M., and Ringe, D. (1998) Biochemistry 37, 4958-4967
27. Malashkevich, V. N., Jager, J., Ziak, M., Sauder, U., Gehring, H., Christen, P., and Jansonius, J. N. (1995) Biochemistry 34, 405-414
28. Christen, P., Kasper, P., Gehring, H., and Sterk, M. (1996) FEBS Lett. 389, 12-14
29. Mehta, P. K., and Christen, P. (2000) Adv. Enzymol. Relat. Areas Mol. Biol. 74, 129-184
30. Eliot, A. C., and Kirsch, J. F. (2004) Annu. Rev. Biochem. 73, 383-415
31. Ziak, M., Jaussi, R., Gehring, H., and Christen, P. (1990) Eur. J. Biochem. 187, 329-333
32. Ziak, M., Jäger, J., Malashkevich, V. N., Gehring, H., Jaussi, R., Jansonius, J. N., and Christen, P. (1993) Eur. J. Biochem. 211, 475-484
33. Dunathan, H. C. (1971) Adv. Enzymol. Relat. Areas Mol. Biol. 35, 79-134