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Volumn 91, Issue 8, 2006, Pages 3189-3198

Mechanisms of irregular bleeding with hormone therapy: The role of matrix metalloproteinases and their tissue inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTROGEN; GELATINASE B; GESTAGEN; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE INHIBITOR; MEDROXYPROGESTERONE ACETATE; NORETHISTERONE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TISSUE INHIBITOR OF METALLOPROTEINASE 4;

EID: 33747712589     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2005-2748     Document Type: Article
Times cited : (26)

References (45)
  • 1
    • 0035026890 scopus 로고    scopus 로고
    • Oral estrogen replacement therapy versus placebo for hot flushes: A systematic review
    • MacLennan A, Lester S, Moore V 2001 Oral estrogen replacement therapy versus placebo for hot flushes: a systematic review. Climacteric 4:58-74
    • (2001) Climacteric , vol.4 , pp. 58-74
    • MacLennan, A.1    Lester, S.2    Moore, V.3
  • 4
    • 0032079997 scopus 로고    scopus 로고
    • Unexpected vaginal bleeding and associated gynecologic care in postmenopausal women using hormone replacement therapy: Comparison of cyclic versus continuous combined schedules
    • Ettinger B, Li DK, Klein R 1998 Unexpected vaginal bleeding and associated gynecologic care in postmenopausal women using hormone replacement therapy: comparison of cyclic versus continuous combined schedules. Fertil Steril 69:865-869
    • (1998) Fertil Steril , vol.69 , pp. 865-869
    • Ettinger, B.1    Li, D.K.2    Klein, R.3
  • 5
    • 0345377658 scopus 로고    scopus 로고
    • The value of outpatient hysteroscopy in diagnosing endometrial pathology in postmenopausal women with and without hormone replacement therapy
    • Elliott J, Connor ME, Lashen H 2003 The value of outpatient hysteroscopy in diagnosing endometrial pathology in postmenopausal women with and without hormone replacement therapy. Acta Obstet Gynecol Scand 82:1112-1119
    • (2003) Acta Obstet Gynecol Scand , vol.82 , pp. 1112-1119
    • Elliott, J.1    Connor, M.E.2    Lashen, H.3
  • 6
    • 0033823889 scopus 로고    scopus 로고
    • Disturbances of endometrial bleeding with hormone replacement therapy
    • Thomas AM, Hickey M, Fraser IS 2000 Disturbances of endometrial bleeding with hormone replacement therapy. Hum Reprod 15(Suppl 3):7-17
    • (2000) Hum Reprod , vol.15 , Issue.3 SUPPL. , pp. 7-17
    • Thomas, A.M.1    Hickey, M.2    Fraser, I.S.3
  • 7
    • 0037722679 scopus 로고    scopus 로고
    • Changes in endometrial blood vessels in the endometrium of women with hormone replacement therapy-related irregular bleeding
    • Hickey M, Pillai G, Higham JM, Sullivan M, Horncastle D, Doherty D, Stamp G 2003 Changes in endometrial blood vessels in the endometrium of women with hormone replacement therapy-related irregular bleeding. Hum Reprod 18:1100-1106
    • (2003) Hum Reprod , vol.18 , pp. 1100-1106
    • Hickey, M.1    Pillai, G.2    Higham, J.M.3    Sullivan, M.4    Horncastle, D.5    Doherty, D.6    Stamp, G.7
  • 8
    • 0037014937 scopus 로고    scopus 로고
    • Effect on endometrium of long term treatment with continuous combined estrogen/progestogen replacement therapy: Follow up study
    • Wells M, Sturdee DW, Barlow DH, Ulrich LG, O'Brien K, Campbell MJ, Vessey MP, Bragg AJ 2002 Effect on endometrium of long term treatment with continuous combined estrogen/progestogen replacement therapy: follow up study. BMJ 325:239-242
    • (2002) BMJ , vol.325 , pp. 239-242
    • Wells, M.1    Sturdee, D.W.2    Barlow, D.H.3    Ulrich, L.G.4    O'Brien, K.5    Campbell, M.J.6    Vessey, M.P.7    Bragg, A.J.8
  • 9
    • 0035142761 scopus 로고    scopus 로고
    • Endometrial bleeding in hormone replacement therapy users: Preliminary findings regarding the role of matrix metalloproteinase 9 (MMP-9) and tissue inhibitors of MMPs
    • Hickey M, Higham J, Sullivan M, Miles L, Fraser IS 2001 Endometrial bleeding in hormone replacement therapy users: preliminary findings regarding the role of matrix metalloproteinase 9 (MMP-9) and tissue inhibitors of MMPs. Fertil Steril 75:288-296
    • (2001) Fertil Steril , vol.75 , pp. 288-296
    • Hickey, M.1    Higham, J.2    Sullivan, M.3    Miles, L.4    Fraser, I.S.5
  • 13
    • 26244461583 scopus 로고    scopus 로고
    • Response of matrix metalloproteinases and tissue inhibitors of metalloproteinases messenger ribonucleic acids to ovarian steroids in human endometrial explants mimics their gene- And phase-specific differential control in vivo
    • Vassilev V, Pretto CM, Cornet PB, Delvaux D, Eeckhout Y, Courtoy PJ, Marbaix E, Henriet P 2005 Response of matrix metalloproteinases and tissue inhibitors of metalloproteinases messenger ribonucleic acids to ovarian steroids in human endometrial explants mimics their gene- and phase-specific differential control in vivo. J Clin Endocrinol Metab 90:5848-5857
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 5848-5857
    • Vassilev, V.1    Pretto, C.M.2    Cornet, P.B.3    Delvaux, D.4    Eeckhout, Y.5    Courtoy, P.J.6    Marbaix, E.7    Henriet, P.8
  • 14
    • 0033966536 scopus 로고    scopus 로고
    • Progesterone inhibits activation of latent matrix metalloproteinase (MMP)-2 by membrane-type 1 MMP: Enzymes coordinately expressed in human endometrium
    • Zhang J, Hampton AL, Nie G, Salamonsen LA 2000 Progesterone inhibits activation of latent matrix metalloproteinase (MMP)-2 by membrane-type 1 MMP: enzymes coordinately expressed in human endometrium. Biol Reprod 62:85-94
    • (2000) Biol Reprod , vol.62 , pp. 85-94
    • Zhang, J.1    Hampton, A.L.2    Nie, G.3    Salamonsen, L.A.4
  • 15
    • 0036090224 scopus 로고    scopus 로고
    • In vivo evidence for active matrix metalloproteinases in human endometrium supports their role in tissue breakdown at menstruation
    • Zhang J, Salamonsen LA 2002 In vivo evidence for active matrix metalloproteinases in human endometrium supports their role in tissue breakdown at menstruation. J Clin Endocrinol Metab 87:2346-2351
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2346-2351
    • Zhang, J.1    Salamonsen, L.A.2
  • 16
    • 0033031512 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase-9 in endometrium during the menstrual cycle and following administration of intrauterine levonorgestrel
    • Skinner JL, Riley SC, Gebbie AE, Glasier AF, Critchley HO 1999 Regulation of matrix metalloproteinase-9 in endometrium during the menstrual cycle and following administration of intrauterine levonorgestrel. Hum Reprod 14:793-799
    • (1999) Hum Reprod , vol.14 , pp. 793-799
    • Skinner, J.L.1    Riley, S.C.2    Gebbie, A.E.3    Glasier, A.F.4    Critchley, H.O.5
  • 18
    • 0036099773 scopus 로고    scopus 로고
    • Decreased tissue inhibitor of metalloproteinase in the endometrium of women using depot medroxyprogesterone acetate: A role for altered endometrial matrix metalloproteinase/tissue inhibitor of metalloproteinase balance in the pathogenesis of abnormal uterine bleeding?
    • Vincent AJ, Zhang J, Ostor A, Rogers PA, Affandi B, Kovacs G, Salamonsen LA 2002 Decreased tissue inhibitor of metalloproteinase in the endometrium of women using depot medroxyprogesterone acetate: a role for altered endometrial matrix metalloproteinase/tissue inhibitor of metalloproteinase balance in the pathogenesis of abnormal uterine bleeding? Hum Reprod 17:1189-1198
    • (2002) Hum Reprod , vol.17 , pp. 1189-1198
    • Vincent, A.J.1    Zhang, J.2    Ostor, A.3    Rogers, P.A.4    Affandi, B.5    Kovacs, G.6    Salamonsen, L.A.7
  • 19
    • 0029658013 scopus 로고    scopus 로고
    • Effects of high dose progestogens on white cells and necrosis in human endometrium
    • Song JY, Russell P, Markham R, Manconi F, Fraser IS 1996 Effects of high dose progestogens on white cells and necrosis in human endometrium. Hum Reprod 11:1713-1718
    • (1996) Hum Reprod , vol.11 , pp. 1713-1718
    • Song, J.Y.1    Russell, P.2    Markham, R.3    Manconi, F.4    Fraser, I.S.5
  • 20
    • 0033824167 scopus 로고    scopus 로고
    • The role of matrix metalloproteinases and leukocytes in abnormal uterine bleeding associated with progestin-only contraceptives
    • Vincent AJ, Salamonsen LA 2000 The role of matrix metalloproteinases and leukocytes in abnormal uterine bleeding associated with progestin-only contraceptives. Hum Reprod 15(Suppl 3):135-143
    • (2000) Hum Reprod , vol.15 , Issue.3 SUPPL. , pp. 135-143
    • Vincent, A.J.1    Salamonsen, L.A.2
  • 21
    • 0025775599 scopus 로고
    • Menstrual bleeding patterns in untreated women and with long-acting methods of contraception
    • Task Force on Long-Acting Systemic Agents for Fertility Regulation
    • Belsey EM 1991 Menstrual bleeding patterns in untreated women and with long-acting methods of contraception. Task Force on Long-Acting Systemic Agents for Fertility Regulation. Adv Contracept 7:257-270
    • (1991) Adv Contracept , vol.7 , pp. 257-270
    • Belsey, E.M.1
  • 23
    • 0032526166 scopus 로고    scopus 로고
    • Extending the simple linear regression model to account for correlated responses: An introduction to generalized estimating equations and multi-level mixed modelling
    • Burton P, Gurrin L, Sly P 1998 Extending the simple linear regression model to account for correlated responses: an introduction to generalized estimating equations and multi-level mixed modelling. Stat Med 17:1261-1291
    • (1998) Stat Med , vol.17 , pp. 1261-1291
    • Burton, P.1    Gurrin, L.2    Sly, P.3
  • 26
    • 0036173982 scopus 로고    scopus 로고
    • Inhibition of activator protein-1 binding activity and phosphatidylinositol 3-kinase pathway by nobiletin, a polymethoxy flavonoid, results in augmentation of tissue inhibitor of metalloproteinases-1 production and suppression of production of matrix metalloproteinases-1 and -9 in human fibrosarcoma HT-1080 cells
    • Sato T, Koike L, Miyata Y, Hirata M, Mimaki Y, Sashida Y, Yano M, Ito A 2002 Inhibition of activator protein-1 binding activity and phosphatidylinositol 3-kinase pathway by nobiletin, a polymethoxy flavonoid, results in augmentation of tissue inhibitor of metalloproteinases-1 production and suppression of production of matrix metalloproteinases-1 and -9 in human fibrosarcoma HT-1080 cells. Cancer Res 62:1025-1029
    • (2002) Cancer Res , vol.62 , pp. 1025-1029
    • Sato, T.1    Koike, L.2    Miyata, Y.3    Hirata, M.4    Mimaki, Y.5    Sashida, Y.6    Yano, M.7    Ito, A.8
  • 27
    • 0036171194 scopus 로고    scopus 로고
    • Oncostatin M stimulates tissue inhibitor of metalloproteinase-1 via a MEK-sensitive mechanism in human myofibroblasts
    • Sohara N, Trojanowska M, Reuben A 2002 Oncostatin M stimulates tissue inhibitor of metalloproteinase-1 via a MEK-sensitive mechanism in human myofibroblasts. J Hepatol 36:191-199
    • (2002) J Hepatol , vol.36 , pp. 191-199
    • Sohara, N.1    Trojanowska, M.2    Reuben, A.3
  • 28
    • 0034954090 scopus 로고    scopus 로고
    • Hormone replacement therapy and irregular bleeding
    • Hickey M, Higham JM, Fraser IS 2001 Hormone replacement therapy and irregular bleeding. Climacteric 4:95-101
    • (2001) Climacteric , vol.4 , pp. 95-101
    • Hickey, M.1    Higham, J.M.2    Fraser, I.S.3
  • 30
    • 5044250714 scopus 로고    scopus 로고
    • Endometrial TIMP-4 mRNA is high at midcycle and in hyperplasia, but down-regulated in malignant tumours. Coordinated expression with MMP-26
    • Pilka R, Domanski H, Hansson S, Eriksson P, Casslen B 2004 Endometrial TIMP-4 mRNA is high at midcycle and in hyperplasia, but down-regulated in malignant tumours. Coordinated expression with MMP-26. Mol Hum Reprod 10:641-650
    • (2004) Mol Hum Reprod , vol.10 , pp. 641-650
    • Pilka, R.1    Domanski, H.2    Hansson, S.3    Eriksson, P.4    Casslen, B.5
  • 31
    • 0041334206 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinase-26 and tissue inhibitor of matrix metalloproteinase-3 and -4 in endometrium throughout the normal menstrual cycle and alteration in users of levonorgestrel implants who experience irregular uterine bleeding
    • Chegini N, Rhoton-Vlasak A, Williams RS 2003 Expression of matrix metalloproteinase-26 and tissue inhibitor of matrix metalloproteinase-3 and -4 in endometrium throughout the normal menstrual cycle and alteration in users of levonorgestrel implants who experience irregular uterine bleeding. Fertil Steril 80:564-570
    • (2003) Fertil Steril , vol.80 , pp. 564-570
    • Chegini, N.1    Rhoton-Vlasak, A.2    Williams, R.S.3
  • 32
    • 0027383944 scopus 로고
    • Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular endothelial cell proliferation
    • Murphy AN, Unsworth EJ, Stetler-Stevenson WG 1993 Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular endothelial cell proliferation. J Cell Physiol 157:351-358
    • (1993) J Cell Physiol , vol.157 , pp. 351-358
    • Murphy, A.N.1    Unsworth, E.J.2    Stetler-Stevenson, W.G.3
  • 33
    • 0033776892 scopus 로고    scopus 로고
    • Effect of different cyclical sequential progestins on endometrial vascularity in postmenopausal women compared with the natural cycle: A morphometric analysis
    • Wahab M, Thompson J, Al-Azzawi F 2000 Effect of different cyclical sequential progestins on endometrial vascularity in postmenopausal women compared with the natural cycle: a morphometric analysis. Hum Reprod 15:2075-2081
    • (2000) Hum Reprod , vol.15 , pp. 2075-2081
    • Wahab, M.1    Thompson, J.2    Al-Azzawi, F.3
  • 34
    • 1642555940 scopus 로고    scopus 로고
    • Angiogenic factors and the endometrium following long term progestin only contraception
    • Lockwood CJ, Schatz F, Krikun G 2004 Angiogenic factors and the endometrium following long term progestin only contraception. Histol Histopathol 19:167-172
    • (2004) Histol Histopathol , vol.19 , pp. 167-172
    • Lockwood, C.J.1    Schatz, F.2    Krikun, G.3
  • 35
    • 0033824337 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinases in human endometrium
    • Salamonsen LA, Zhang J, Hampton A, Lathbury L 2000 Regulation of matrix metalloproteinases in human endometrium. Hum Reprod 15(Suppl 3):112-119
    • (2000) Hum Reprod , vol.15 , Issue.3 SUPPL. , pp. 112-119
    • Salamonsen, L.A.1    Zhang, J.2    Hampton, A.3    Lathbury, L.4
  • 36
    • 29144462031 scopus 로고    scopus 로고
    • A pilot study to assess the effect of three short-term treatments on frequent and/or prolonged bleeding compared to placebo in women using Implanon
    • Weisberg E, Hickey M, Palmer D, O'Connor V, Salamonsen LA, Findlay JK, Fraser IS 2006 A pilot study to assess the effect of three short-term treatments on frequent and/or prolonged bleeding compared to placebo in women using Implanon. Hum Reprod 21:295-302
    • (2006) Hum Reprod , vol.21 , pp. 295-302
    • Weisberg, E.1    Hickey, M.2    Palmer, D.3    O'Connor, V.4    Salamonsen, L.A.5    Findlay, J.K.6    Fraser, I.S.7
  • 37
    • 0037206409 scopus 로고    scopus 로고
    • Leukocyte networks and human endometrial remodelling
    • Salamonsen LA, Zhang J, Brasted M 2002 Leukocyte networks and human endometrial remodelling. J Reprod Immunol 57:95-108
    • (2002) J Reprod Immunol , vol.57 , pp. 95-108
    • Salamonsen, L.A.1    Zhang, J.2    Brasted, M.3
  • 38
    • 0037499867 scopus 로고    scopus 로고
    • Pathophysiology of endometrial bleeding
    • Ferenczy A 2003 Pathophysiology of endometrial bleeding. Maturitas 45:1-14
    • (2003) Maturitas , vol.45 , pp. 1-14
    • Ferenczy, A.1
  • 39
    • 0028855894 scopus 로고
    • IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes
    • Lacraz S, Nicod LP, Chicheportiche R, Welgus HG, Dayer JM 1995 IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes. J Clin Invest 96:2304-2310
    • (1995) J Clin Invest , vol.96 , pp. 2304-2310
    • Lacraz, S.1    Nicod, L.P.2    Chicheportiche, R.3    Welgus, H.G.4    Dayer, J.M.5
  • 42
    • 0026084918 scopus 로고
    • Hormonal changes associated with bleeding during low dose progestogen contraception delivered by Norplant subdermal implants
    • Faundes A, Alvarez-Sanchez F, Brache V, Jimenez E, Tejada AS 1991 Hormonal changes associated with bleeding during low dose progestogen contraception delivered by Norplant subdermal implants. Adv Contracept 7:85-94
    • (1991) Adv Contracept , vol.7 , pp. 85-94
    • Faundes, A.1    Alvarez-Sanchez, F.2    Brache, V.3    Jimenez, E.4    Tejada, A.S.5
  • 43
    • 30544450747 scopus 로고    scopus 로고
    • Vasomotor symptom relief versus unwanted effects: Role of estrogen dosage
    • Ettinger B 2005 Vasomotor symptom relief versus unwanted effects: role of estrogen dosage. Am J Med 118:74-78
    • (2005) Am J Med , vol.118 , pp. 74-78
    • Ettinger, B.1
  • 44
    • 28044438461 scopus 로고    scopus 로고
    • The performance of Pipelle endometrial sampling in a dedicated postmenopausal bleeding clinic
    • Elsandabesee D, Greenwood P 2005 The performance of Pipelle endometrial sampling in a dedicated postmenopausal bleeding clinic. J Obstet Gynaecol 25:32-34
    • (2005) J Obstet Gynaecol , vol.25 , pp. 32-34
    • Elsandabesee, D.1    Greenwood, P.2
  • 45
    • 0033824168 scopus 로고    scopus 로고
    • The role of tissue factor in regulating endometrial haemostasis: Implications for progestin-only contraception
    • Lockwood CJ, Runic R, Wan L, Krikun G, Demopolous R, Schatz F 2000 The role of tissue factor in regulating endometrial haemostasis: implications for progestin-only contraception. Hum Reprod 15(Suppl 3):144-151
    • (2000) Hum Reprod , vol.15 , Issue.3 SUPPL. , pp. 144-151
    • Lockwood, C.J.1    Runic, R.2    Wan, L.3    Krikun, G.4    Demopolous, R.5    Schatz, F.6


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