The effects of long chain-length n-alcohols on the firing frequency of dopaminergic neurons of the ventral tegmental area

Journal of Pharmacology and Experimental Therapeutics

Volumn 318, Issue 3, 2006, Pages 1137-1145

  Appel, Sarah B ^a   Wise, Leon ^a   McDaid, John ^a   Koyama, Susumu ^a   McElvain, Maureen A ^a   Brodie, Mark S ^a,b  

^a UNIVERSITY OF ILLINOIS   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DERIVATIVE; BUTANOL; HEPTANOL; HEXANOL; METHANOL; PENTANOL;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; DISSOCIATION; DOPAMINERGIC NERVE CELL; DRUG ABUSE; HYDROPHOBICITY; IN VITRO STUDY; MALE; MEMBRANE POTENTIAL; NERVE EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; RAT; VENTRAL TEGMENTUM;

ALCOHOLS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHYLENE CHLOROHYDRIN; HYDROPHOBICITY; MALE; MEMBRANE POTENTIALS; RATS; RATS, INBRED F344; STRUCTURE-ACTIVITY RELATIONSHIP; VENTRAL TEGMENTAL AREA;

EID: 33747614110     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.105148     Document Type: Article

References (43)

1. Allan AM and Harris RA (1987) Involvement of neuronal chloride channels in ethanol intoxication, tolerance, and dependence. Recent Dev Alcohol 5:313-325.
2. Anantharam V, Bayley H, Wilson A, and Treistman SN (1992) Differential effects of ethanol on electrical properties of various potassium channels expressed in oocytes. Mol Pharmacol 42:499-505.
3. Appel SB, Liu Z, McElvain MA, and Brodie MS (2003) Ethanol excitation of dopaminergic ventral tegmental area neurons is blocked by quinidine. J Pharmacol Exp Ther 306:437-446.
4. Appel SB, Liu ZP, McElvain MA, and Brodie MS (2000) Ethanol excitation of dopaminergic ventral tegmental area neurons is blocked by quinidine. Alcohol Clin Exp Res 24:7A.
5. Brodie MS and Appel SB (1998) The effects of ethanol on dopaminergic neurons of the ventral tegmental area studied with intracellular recording in brain slices. Alcohol Clin Exp Res 22:236-244.
6. Brodie MS, McElvain MA, Bunney EB, and Appel SB (1999a) Pharmacological reduction of small conductance calcium-activated potassium current (SK) potentiates the excitatory effect of ethanol on ventral tegmental area dopamine neurons. J Pharmacol Exp Ther 290:325-333.
7. Brodie MS, Pesold C, and Appel SB (1999b) Ethanol directly excites dopaminergic ventral tegmental area reward neurons. Alcohol Clin Exper Res 23:1848-1852.
8. Brodie MS, Shefner SA, and Dunwiddie TV (1990) Ethanol increases the firing rate of dopamine neurons of the rat ventral tegmental area in vitro. Brain Res 508:65-69.
9. Covarrubias M, Vyas TB, Escobar L, and Wei A (1995) Alcohols inhibit a cloned potassium channel at a discrete saturable site. Insights into the molecular basis of general anesthesia. J Biol Chem 270:19408-19416.
10. Cunningham CL, Malott DH, Dickinson SD, and Risinger FO (1992) Haloperidol does not alter expression of ethanol-induced conditioned place preference. Behav Brain Res 50:1-5.
11. Deutch AY, Moghaddam B, Innis RB, Krystal JH, Aghajanian GK, Bunney BS, and Charney DS (1991) Mechanisms of action of atypical antipsychotic drugs. Implications for novel therapeutic strategies for schizophrenia. Schizophr Res 4:121-156.
12. Di Chiara G and Imperato A (1988) Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic dopamine system of freely moving rats. Proc Natl Acad Sci USA 85:5274-5278.
13. + channels in isolated neurohypophysial terminals. Mol Pharmacol 49:40-48.
14. Franks NP and Lieb WR (1985) Mapping of general anaesthetic target sites provides a molecular basis for cutoff effects. Nature (Lond) 316:349-351.
15. Franks NP and Lieb WR (1986) Partitioning of long-chain alcohols into lipid bilayers: implications for mechanisms of general anesthesia. Proc Natl Acad Sci USA 83:5116-5120.
16. Gessa GL, Muntoni F, Collu M, Vargiu L, and Mereu G (1985) Low doses of ethanol activate dopaminergic neurons in the ventral tegmental area. Brain Res 348:201-203.
17. Grace AA and Bunney BS (1986) Induction of depolarization block in midbrain dopamine neurons by repeated administration of haloperidol: analysis using in vivo intracellular recording. J Pharmacol Exp Ther 238:1092-1100.
18. Haggard HW, Greenberg LA, and Rakieten N (1940) Studies on the absorption, distribution and elimination of alcohol. VI. The principles governing the concentration of alcohol in the blood and the concentration causing respiratory failure. J Pharmacol Exp Ther 69:252-265.
19. Hobbs WR, Rall TW, and Verdoorn TA (1996) Hypnotics and sedatives; ethanol, in Goodman and Gilman's The Pharmacological Basis of Therapeutics (Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, and Gilman AG eds) pp 361-396, McGraw-Hill, New York.
20. Koyama S and Appel SB (2006) Characterization of M-current in ventral tegmental area dopamine neurons. J Neurophysiol 96:535-543.
21. Koyama S, Kanemitsu Y, and Weight FF (2005) Spontaneous activity and properties of two types of principal neurons from the ventral tegmental area of rat. J Neurophysiol 93:3282-3293.
22. A, glycine and GABA rho 1 receptors. J Pharmacol Exp Ther 284:934-942.
23. Lacey MG, Mercuri NB, and North RA (1989) Two cell types in rat substantia nigra zona compacta distinguished by membrane properties and the actions of dopamine and opioids. J Neurosci 9:1233-1241.
24. Lovinger DM (1990) Ethanol (EtOH) potentiates ion current mediated by 5HT receptors in NCB-20 cells. Alcohol Clin Exp Res 14:313.
25. Lovinger DM, Sung KW, and Zhou Q (2000) Ethanol and trichloroethanol alter gating of 5-HT3 receptor-channels in NCB-20 neuroblastoma cells. Neuropharmacology 39:561-570.
26. Lovinger DM, White G, and Weight FF (1990) NMDA receptor-mediated synaptic excitation selectively inhibited by ethanol in hippocampal slice from adult rat. J Neurosci 10:1372-1379.
27. Lyon RC, McComb JA, Schreurs J, and Goldstein DB (1981) A relationship between alcohol intoxication and the disordering of brain membranes by a series of shortchain alcohols. J Pharmacol Exp Ther 218:669-675.
28. Majchrowicz E and Hunt WA (1976) Temporal relationship of the induction of tolerance and physical dependence after continuous intoxication with maximum tolerable doses of ethanol in rats. Psychopharmacology (Berl) 50:107-112.
29. McCreery MJ and Hunt WA (1978) Physico-chemical correlates of alcohol intoxication. Neuropharmacology 17:451-461.
30. Mueller AL and Brodie MS (1989) Intracellular recording from putative dopamine-containing neurons in the ventral tegmental area of Tsai in a brain slice preparation. J Neurosci Methods 28:15-22.
31. Neher E (1992) Correction for liquid junction potentials in patch clamp experiments. Methods Enzymol 207:123-131.
32. Oades RD and Halliday GM (1987) Ventral tegmental (A10) system: neurobiology. 1. Anatomy and connectivity. Brain Res Rev 12:117-165.
33. Peoples RW and Weight FF (1995) Cutoff in potency implicates alcohol inhibition of N-methyl-D-aspartate receptors in alcohol intoxication. Proc Natl Acad Sci USA 92:2825-2829.
34. Price KL and Middaugh LD (2004) The dopamine D1 antagonist reduces ethanol reward for C57BL/6 mice. Alcohol Clin Exp Res 28:1666-1675.
35. Risinger FO, Dickinson SD, and Cunningham CL (1992) Haloperidol reduces ethanol-induced motor activity stimulation but not conditioned place preference. Psychopharmacology (Berl) 107:453-456.
36. Robinson JT (1966) A case of chloral hydrate addiction. Int J Soc Psychiatry 12:66-71.
37. Rodd-Henricks ZA, McKinzie DL, Crile RS, Murphy JM, and McBride WJ (2000) Regional heterogeneity for the intracranial self-administration of ethanol within the ventral tegmental area of female Wistar rats. Psychopharmacology (Berl) 149:217-224.
38. Samson HH, Tolliver GA, and Schwarz-Stevens K (1990) Oral ethanol selfadministration: a behavioral pharmacological approach to CNS control mechanisms. Alcohol 7:187-191.
39. Shen R-Y and Chiodo LA (1993) Acute withdrawal after repeated ethanol treatment reduces the number of spontaneously active dopaminergic neurons in the ventral tegmental area. Brain Res 622:289-293.
40. Thanos PK, Katana JM, Ashby CR Jr, Michaelides M, Gardner EL, Heidbreder CA, and Volkow ND (2005) The selective dopamine D3 receptor antagonist SB-277011-A attenuates ethanol consumption in ethanol preferring (P) and non-preferring (NP) rats. Pharmacol Biochem Behav 81:190-197.
41. Wallgren H (1960) Relative intoxicating effects on rats of ethyl, propyl and butyl alcohols. Acta Pharmacol Toxicol (Copenh) 16:217-222.
42. Weiss F, Lorang MT, Bloom FE, and Koob GF (1993) Oral alcohol self-administration stimulates dopamine release in the rat nucleus accumbens: genetic and motivational determinants. J Pharmacol Exp Ther 267:250-258.
43. Wise RA (1996) Neurobiology of addiction. Curr Opin Neurobiol 6:243-251.