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Volumn 39, Issue 8, 2006, Pages 1480-1488

Hibernating bears as a model for preventing disuse osteoporosis

Author keywords

Aging; Black bear; Bone mechanical properties; Bone remodeling; Disuse osteoporosis; Hibernation

Indexed keywords

BIOMECHANICS; BONE; DISEASES; MATHEMATICAL MODELS; MORPHOLOGY; POROSITY;

EID: 33747608882     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2005.03.030     Document Type: Article
Times cited : (45)

References (46)
  • 1
    • 33747602158 scopus 로고    scopus 로고
    • Barnes, B.M., 2004. Personal communication.
  • 2
    • 0030977163 scopus 로고    scopus 로고
    • Effects of 1- and 6-month spaceflight on bone mass and biochemistry in two humans
    • Collet P., Uebelhart D., Vico L., Moro L., Hartmann D., Roth M., and Alexandre C. Effects of 1- and 6-month spaceflight on bone mass and biochemistry in two humans. Bone 20 (1997) 547-551
    • (1997) Bone , vol.20 , pp. 547-551
    • Collet, P.1    Uebelhart, D.2    Vico, L.3    Moro, L.4    Hartmann, D.5    Roth, M.6    Alexandre, C.7
  • 3
    • 0027079067 scopus 로고
    • Reconstructing reproductive histories of black bears from the incremental layering of dental cementum
    • Coy P.L., and Garshelis D.L. Reconstructing reproductive histories of black bears from the incremental layering of dental cementum. Can. J. Zool. 70 (1992) 2150-2160
    • (1992) Can. J. Zool. , vol.70 , pp. 2150-2160
    • Coy, P.L.1    Garshelis, D.L.2
  • 4
    • 0016712050 scopus 로고
    • The mechanical properties of bone tissue in children
    • Currey J.D., and Butler G. The mechanical properties of bone tissue in children. J. Bone J. Surg.. Am. Vol. 57 (1975) 810-814
    • (1975) J. Bone J. Surg.. Am. Vol. , vol.57 , pp. 810-814
    • Currey, J.D.1    Butler, G.2
  • 5
    • 0033910897 scopus 로고    scopus 로고
    • Supralesional and sublesional bone mineral density in spinal cord-injured patients
    • Dauty M., Perrouin Verbe B., Maugars Y., Dubois C., and Mathe J.F. Supralesional and sublesional bone mineral density in spinal cord-injured patients. Bone 27 (2000) 305-309
    • (2000) Bone , vol.27 , pp. 305-309
    • Dauty, M.1    Perrouin Verbe, B.2    Maugars, Y.3    Dubois, C.4    Mathe, J.F.5
  • 7
    • 33747618796 scopus 로고    scopus 로고
    • Donahue, S.W., Harvey, K.B., 2004. Bone strength is not compromised with aging in black bears (Ursus americanus) despite annual periods of disuse (hibernation). American Society of Biomechanics 28th Annual Conference, Portland, OR.
  • 8
    • 0345801334 scopus 로고    scopus 로고
    • Bone formation is not impaired by hibernation (disuse) in black bears Ursus americanus
    • Donahue S.W., Vaughan M.R., Demers L.M., and Donahue H.J. Bone formation is not impaired by hibernation (disuse) in black bears Ursus americanus. J. Exp. Biol. 206 (2003) 4233-4239
    • (2003) J. Exp. Biol. , vol.206 , pp. 4233-4239
    • Donahue, S.W.1    Vaughan, M.R.2    Demers, L.M.3    Donahue, H.J.4
  • 10
    • 33747626578 scopus 로고    scopus 로고
    • 2 release in MC-3T3 osteoblastic cells. 50th Annual Meeting of the Orthopaedic Research Society, San Francisco, CA.
  • 11
    • 0027409581 scopus 로고
    • Serum markers of type I collagen formation and degradation in metabolic bone disease: correlation with bone histomorphometry
    • Eriksen E.F., Charles P., Melsen F., Mosekilde L., Risteli L., and Risteli J. Serum markers of type I collagen formation and degradation in metabolic bone disease: correlation with bone histomorphometry. J. Bone Miner. Res. 8 (1993) 127-132
    • (1993) J. Bone Miner. Res. , vol.8 , pp. 127-132
    • Eriksen, E.F.1    Charles, P.2    Melsen, F.3    Mosekilde, L.4    Risteli, L.5    Risteli, J.6
  • 12
    • 0025368588 scopus 로고
    • Calcium and bone metabolic homeostasis in active and denning black bears (Ursus americanus)
    • Floyd T., Nelson R.A., and Wynne G.F. Calcium and bone metabolic homeostasis in active and denning black bears (Ursus americanus). Clin. Orthop. Relat. Res. 255 (1990) 301-309
    • (1990) Clin. Orthop. Relat. Res. , vol.255 , pp. 301-309
    • Floyd, T.1    Nelson, R.A.2    Wynne, G.F.3
  • 13
    • 0023492075 scopus 로고
    • Bone "mass" and the "mechanostat": a proposal
    • Frost H.M. Bone "mass" and the "mechanostat": a proposal. Anat. Rec. 219 (1987) 1-9
    • (1987) Anat. Rec. , vol.219 , pp. 1-9
    • Frost, H.M.1
  • 15
    • 0017816934 scopus 로고
    • Effects of hibernation on interradicular alveolar bone
    • Haller A.C., and Zimny M.L. Effects of hibernation on interradicular alveolar bone. J. Dent. Res. 56 (1977) 1552-1557
    • (1977) J. Dent. Res. , vol.56 , pp. 1552-1557
    • Haller, A.C.1    Zimny, M.L.2
  • 17
    • 2642516523 scopus 로고    scopus 로고
    • Body surface temperature of hibernating black bears may be related to periodic muscle activity
    • Harlow H.J., Lohuis T., Anderson-Sprecher R.C., and Beck T.D.I. Body surface temperature of hibernating black bears may be related to periodic muscle activity. J. Mammal. 85 (2004) 414-419
    • (2004) J. Mammal. , vol.85 , pp. 414-419
    • Harlow, H.J.1    Lohuis, T.2    Anderson-Sprecher, R.C.3    Beck, T.D.I.4
  • 18
    • 4344657917 scopus 로고    scopus 로고
    • Bending properties, porosity, and ash fraction of black bear (Ursus americanus) cortical bone are not compromised with aging despite annual periods of disuse
    • Harvey K.B., and Donahue S.W. Bending properties, porosity, and ash fraction of black bear (Ursus americanus) cortical bone are not compromised with aging despite annual periods of disuse. J. Biomech. 37 (2004) 1513-1520
    • (2004) J. Biomech. , vol.37 , pp. 1513-1520
    • Harvey, K.B.1    Donahue, S.W.2
  • 19
    • 0001741906 scopus 로고    scopus 로고
    • Physiology of hibernation in bears
    • Hellgren E.C. Physiology of hibernation in bears. Ursus 10 (1998) 467-477
    • (1998) Ursus , vol.10 , pp. 467-477
    • Hellgren, E.C.1
  • 20
    • 0022851394 scopus 로고
    • Reversibility of nontraumatic disuse osteoporosis during its active phase
    • Jaworski Z.F., and Uhthoff H.K. Reversibility of nontraumatic disuse osteoporosis during its active phase. Bone 7 (1986) 431-439
    • (1986) Bone , vol.7 , pp. 431-439
    • Jaworski, Z.F.1    Uhthoff, H.K.2
  • 21
    • 0030696015 scopus 로고    scopus 로고
    • The in vivo anabolic actions of prostaglandins in bone
    • Jee W.S., and Ma Y.F. The in vivo anabolic actions of prostaglandins in bone. Bone 21 (1997) 297-304
    • (1997) Bone , vol.21 , pp. 297-304
    • Jee, W.S.1    Ma, Y.F.2
  • 22
    • 0030719898 scopus 로고    scopus 로고
    • Changes in canine cortical and cancellous bone mechanical properties following immobilization and remobilization with exercise
    • Kaneps A.J., Stover S.M., and Lane N.E. Changes in canine cortical and cancellous bone mechanical properties following immobilization and remobilization with exercise. Bone 21 (1997) 419-423
    • (1997) Bone , vol.21 , pp. 419-423
    • Kaneps, A.J.1    Stover, S.M.2    Lane, N.E.3
  • 23
    • 0023179525 scopus 로고
    • Annual skeletal changes in the little brown bat, Myotis lucifugus lucifugus, with particular reference to pregnancy and lactation
    • Kwiecinski G.G., Krook L., and Wimsatt W.A. Annual skeletal changes in the little brown bat, Myotis lucifugus lucifugus, with particular reference to pregnancy and lactation. Am. J. Anat. 178 (1987) 410-420
    • (1987) Am. J. Anat. , vol.178 , pp. 410-420
    • Kwiecinski, G.G.1    Krook, L.2    Wimsatt, W.A.3
  • 24
    • 12344309568 scopus 로고    scopus 로고
    • Cortical and trabecular bone mineral loss from the spine and hip in long-duration spaceflight
    • Lang T., LeBlanc A., Evans H., Lu Y., Genant H., and Yu A. Cortical and trabecular bone mineral loss from the spine and hip in long-duration spaceflight. J. Bone Miner. Res. 19 (2004) 1006-1012
    • (2004) J. Bone Miner. Res. , vol.19 , pp. 1006-1012
    • Lang, T.1    LeBlanc, A.2    Evans, H.3    Lu, Y.4    Genant, H.5    Yu, A.6
  • 26
    • 33747587913 scopus 로고    scopus 로고
    • Lin, D.C., Egeland, L.A., Schertenleib, K.W., Nelson, O.L., Robbins, C.T., 2004. Intermittent muscle activation in grizzly bears during hibernation: a strategy to prevent muscle atrophy? Society for Neuroscience Annual meeting, San Diego, CA.
  • 27
    • 0017656822 scopus 로고
    • The reversibility of disuse osteoporosis: studies of bone density, bone formation, and cell proliferation in bone tissue
    • Lindgren U., and Mattsson S. The reversibility of disuse osteoporosis: studies of bone density, bone formation, and cell proliferation in bone tissue. Calcif. Tissue Res. 23 (1977) 179-184
    • (1977) Calcif. Tissue Res. , vol.23 , pp. 179-184
    • Lindgren, U.1    Mattsson, S.2
  • 28
    • 33747590616 scopus 로고    scopus 로고
    • McGee, M.E., Harvey, K.B., Donahue, S.W., 2004. Whole bone bending properties of black bear tibias are not compromised by annual periods of disuse. 2004 BMES Annual Fall Meeting, Philadelphia, Biomedical Engineering Society.
  • 29
    • 3543054147 scopus 로고    scopus 로고
    • Maintenance of bone mass and architecture in denning black bears (Ursus americanus)
    • Pardy C.K., Wohl G.R., Ukrainetz P.J., Sawers A., Boyd S.K., and Zernicke R.F. Maintenance of bone mass and architecture in denning black bears (Ursus americanus). J. Zool. 263 (2004) 359-364
    • (2004) J. Zool. , vol.263 , pp. 359-364
    • Pardy, C.K.1    Wohl, G.R.2    Ukrainetz, P.J.3    Sawers, A.4    Boyd, S.K.5    Zernicke, R.F.6
  • 30
    • 0032710526 scopus 로고    scopus 로고
    • Expression profiles of mRNAs for osteoblast and osteoclast proteins as indicators of bone loss in mouse immobilization osteopenia model
    • Rantakokko J., Uusitalo H., Jamsa T., Tuukkanen J., Aro H.T., and Vuorio E. Expression profiles of mRNAs for osteoblast and osteoclast proteins as indicators of bone loss in mouse immobilization osteopenia model. J. Bone Miner. Res. 14 (1999) 1934-1942
    • (1999) J. Bone Miner. Res. , vol.14 , pp. 1934-1942
    • Rantakokko, J.1    Uusitalo, H.2    Jamsa, T.3    Tuukkanen, J.4    Aro, H.T.5    Vuorio, E.6
  • 31
    • 0034944477 scopus 로고    scopus 로고
    • Constraints on herbiovory by grizzly bears
    • Rode K.D., Robbins C.T., and Shipley L.A. Constraints on herbiovory by grizzly bears. Oecologia 128 (2001) 62-71
    • (2001) Oecologia , vol.128 , pp. 62-71
    • Rode, K.D.1    Robbins, C.T.2    Shipley, L.A.3
  • 32
    • 33747601933 scopus 로고    scopus 로고
    • Rogers, L.L., 2004. Personal communication.
  • 33
    • 0029859197 scopus 로고    scopus 로고
    • Differentiation of the bone-tissue remodeling response to axial and torsional loading in the turkey ulna
    • Rubin C., Gross T., Qin Y.X., Fritton S., Guilak F., and McLeod K. Differentiation of the bone-tissue remodeling response to axial and torsional loading in the turkey ulna. J. Bone J. Surg.. Am. Vol. 78 (1996) 1523-1533
    • (1996) J. Bone J. Surg.. Am. Vol. , vol.78 , pp. 1523-1533
    • Rubin, C.1    Gross, T.2    Qin, Y.X.3    Fritton, S.4    Guilak, F.5    McLeod, K.6
  • 34
    • 0034814210 scopus 로고    scopus 로고
    • The anabolic activity of bone tissue, suppressed by disuse, is normalized by brief exposure to extremely low-magnitude mechanical stimuli
    • Rubin C., Xu G., and Judex S. The anabolic activity of bone tissue, suppressed by disuse, is normalized by brief exposure to extremely low-magnitude mechanical stimuli. Faseb J. 15 (2001) 2225-2229
    • (2001) Faseb J. , vol.15 , pp. 2225-2229
    • Rubin, C.1    Xu, G.2    Judex, S.3
  • 35
    • 0036192588 scopus 로고    scopus 로고
    • Mechanical strain induced noninvasively in the high-frequency domain, is anabolic to cancellous bone, but not cortical bone
    • Rubin C., Turner A.S., Mallinckrodt C., Jerome C., McLeod K., and Bain S. Mechanical strain induced noninvasively in the high-frequency domain, is anabolic to cancellous bone, but not cortical bone. Bone 30 (2002) 445-452
    • (2002) Bone , vol.30 , pp. 445-452
    • Rubin, C.1    Turner, A.S.2    Mallinckrodt, C.3    Jerome, C.4    McLeod, K.5    Bain, S.6
  • 36
    • 0023236362 scopus 로고
    • Mechanical, morphological and biochemical adaptations of bone and muscle to hindlimb suspension and exercise
    • Shaw S.R., Zernicke R.F., Vailas A.C., DeLuna D., Thomason D.B., and Baldwin K.M. Mechanical, morphological and biochemical adaptations of bone and muscle to hindlimb suspension and exercise. J. Biomech. 20 (1987) 225-234
    • (1987) J. Biomech. , vol.20 , pp. 225-234
    • Shaw, S.R.1    Zernicke, R.F.2    Vailas, A.C.3    DeLuna, D.4    Thomason, D.B.5    Baldwin, K.M.6
  • 37
    • 0018559488 scopus 로고
    • Changes observed in bone during hibernation using Procion red dye as a matrical marker
    • Steinberg B., Singh I.J., and Mitchell O.G. Changes observed in bone during hibernation using Procion red dye as a matrical marker. J. Exper. Zool. 210 (1979) 537-541
    • (1979) J. Exper. Zool. , vol.210 , pp. 537-541
    • Steinberg, B.1    Singh, I.J.2    Mitchell, O.G.3
  • 38
    • 0019509470 scopus 로고
    • The effects of cold-stress. Hibernation, and prolonged inactivity on bone dynamics in the golden hamster, Mesocricetus auratus
    • Steinberg B., Singh I.J., and Mitchell O.G. The effects of cold-stress. Hibernation, and prolonged inactivity on bone dynamics in the golden hamster, Mesocricetus auratus. J. Morphol. 167 (1981) 43-51
    • (1981) J. Morphol. , vol.167 , pp. 43-51
    • Steinberg, B.1    Singh, I.J.2    Mitchell, O.G.3
  • 39
    • 0022614250 scopus 로고
    • An autoradiographic study of the uptake of tritiated proline by osteoblasts during hibernation
    • Steinberg B., Singh I.J., and Mitchell O.G. An autoradiographic study of the uptake of tritiated proline by osteoblasts during hibernation. Histol. Histopathol. 1 (1986) 155-160
    • (1986) Histol. Histopathol. , vol.1 , pp. 155-160
    • Steinberg, B.1    Singh, I.J.2    Mitchell, O.G.3
  • 40
    • 0032126660 scopus 로고    scopus 로고
    • Protein use and muscle-fiber changes in free-ranging, hibernating black bears
    • Tinker D.B., Harlow H.J., and Beck T.D. Protein use and muscle-fiber changes in free-ranging, hibernating black bears. Physiol. Zool. 71 (1998) 414-424
    • (1998) Physiol. Zool. , vol.71 , pp. 414-424
    • Tinker, D.B.1    Harlow, H.J.2    Beck, T.D.3
  • 41
    • 0034758201 scopus 로고    scopus 로고
    • Disuse-induced deterioration of bone strength is not stopped after free remobilization in young adult rats
    • Trebacz H. Disuse-induced deterioration of bone strength is not stopped after free remobilization in young adult rats. J. Biomech. 34 (2001) 1631-1636
    • (2001) J. Biomech. , vol.34 , pp. 1631-1636
    • Trebacz, H.1
  • 42
    • 0034612094 scopus 로고    scopus 로고
    • Effects of long-term microgravity exposure on cancellous and cortical weight-bearing bones of cosmonauts
    • Vico L., Collet P., Guignandon A., Lafage-Proust M.H., Thomas T., Rehaillia M., and Alexandre C. Effects of long-term microgravity exposure on cancellous and cortical weight-bearing bones of cosmonauts. Lancet 355 (2000) 1607-1611
    • (2000) Lancet , vol.355 , pp. 1607-1611
    • Vico, L.1    Collet, P.2    Guignandon, A.3    Lafage-Proust, M.H.4    Thomas, T.5    Rehaillia, M.6    Alexandre, C.7
  • 43
    • 0037228053 scopus 로고    scopus 로고
    • Determination of cortical bone porosity and pore size distribution using a low field pulsed NMR approach
    • Wang X., and Ni Q. Determination of cortical bone porosity and pore size distribution using a low field pulsed NMR approach. J. Orthop. Res. 21 (2003) 312-319
    • (2003) J. Orthop. Res. , vol.21 , pp. 312-319
    • Wang, X.1    Ni, Q.2
  • 44
    • 0024448705 scopus 로고
    • Osteopenia in the immobilized rat hind limb is associated with increased bone resorption and decreased bone formation
    • Weinreb M., Rodan G.A., and Thompson D.D. Osteopenia in the immobilized rat hind limb is associated with increased bone resorption and decreased bone formation. Bone 10 (1989) 187-194
    • (1989) Bone , vol.10 , pp. 187-194
    • Weinreb, M.1    Rodan, G.A.2    Thompson, D.D.3
  • 45
    • 0030725819 scopus 로고    scopus 로고
    • Short-term healing kinetics of cortical and cancellous bone osteopenia induced by unloading during the reloading period in young rats
    • Weinreb M., Patael H., Preisler O., and Ben-Shemen S. Short-term healing kinetics of cortical and cancellous bone osteopenia induced by unloading during the reloading period in young rats. Virchows Arch. 431 (1997) 449-452
    • (1997) Virchows Arch. , vol.431 , pp. 449-452
    • Weinreb, M.1    Patael, H.2    Preisler, O.3    Ben-Shemen, S.4
  • 46
    • 0031924775 scopus 로고    scopus 로고
    • Serum concentration of the pyridinoline cross-linked carboxyterminal telopeptide of type I collagen (ICTP) is a useful indicator of decline and recovery of bone mineral density in lumbar spine: analysis in Japanese postmenopausal women with or without hormone replacement
    • Yasumizu T., Hoshi K., Iijima S., and Asaka A. Serum concentration of the pyridinoline cross-linked carboxyterminal telopeptide of type I collagen (ICTP) is a useful indicator of decline and recovery of bone mineral density in lumbar spine: analysis in Japanese postmenopausal women with or without hormone replacement. Endocr. J. 45 (1998) 45-51
    • (1998) Endocr. J. , vol.45 , pp. 45-51
    • Yasumizu, T.1    Hoshi, K.2    Iijima, S.3    Asaka, A.4


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