Prevention of AD: The which, when, and on whom?

Alzheimer Disease and Associated Disorders

Volumn 20, Issue SUPPL. 2, 2006, Pages

  Launer, Lenore J ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Cardiovascular risk; Dementia; Prevention

Indexed keywords

ALZHEIMER DISEASE; BRAIN FUNCTION; CARDIOVASCULAR RISK; COGNITIVE DEFECT; DEMENTIA; DIABETES MELLITUS; HUMAN; NOTE; OUTCOMES RESEARCH; PRIORITY JOURNAL; RISK FACTOR;

AGED; ALZHEIMER DISEASE; BRAIN; HUMANS; OUTCOME ASSESSMENT (HEALTH CARE); PATIENT SELECTION; RISK FACTORS;

EID: 33747606716     PISSN: 08930341     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002093-200607001-00011     Document Type: Note

References (39)

1. Launer LJ, Andersen K, Dewey ME, et al. Rates and risk factors for dementia and Alzheimer's disease: Results from EURODEM pooled analyses. Neurology. 1999;52:78-84.
2. Ott A, Slooter AJ, Hofman A, et al. Smoking and risk of dementia and Alzheimer's disease in a population-based cohort study: the Rotterdam Study. Lancet. 1998;351:1840-1843.
3. Tyas SL, White LR, Petrovitch H, et al. Mid-life smoking and late-life dementia: the Honolulu-Asia Aging Study. Neurobiol Aging. 2003;24:589-596.
4. Laurin D, Verreault R, Lindsay J, et al. Physical activity and risk of cognitive impairment and dementia in elderly persons. Arch Neurol. 2001;58:498-504.
5. Engelhart MJ, Geerlings MI, Ruitenberg A, et al. Dietary intake of antioxidants and risk of Alzheimer disease. JAMA. 2002;287:3223-3229.
6. Kalmijn S, Launer LJ, Ott A, et al. Dietary fat intake and the risk of incident dementia in the Rotterdam Study. Ann Neurol. 1997;42:776-782.
7. Launer LJ, Ross GW, Petrovitch H, et al. Midlife blood pressure and dementia: the Honolulu-Asia aging study. Neurobiol Aging. 2000;21:49-55.
8. Skoog I, Lernfelt B, Landahl S, et al. 15-year longitudinal study of blood pressure and dementia. Lancet. 1996;347:1141-1145.
9. Seshadri S, Beiser A, Selhub J, et al. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med. 2002;14:476-483.
10. Kivipelto M, Helkala EL, Laakso MP, et al. Apolipoprotein E ε4, elevated midlife total cholesterol level, and high systolic blood pressure are independent risk factors for late-life Alzheimer's disease. Ann Intern Med. 2002;137:149-155.
11. Schmidt R, Schmidt H, Curb JD, et al. Early inflammation and dementia: A 25-year follow-up of the Honolulu-Asia Aging Study. Ann Neurol. 2002;52:168-174.
12. de Leeuw FE, De Groot JC, Oudkerk M, et al. Aortic atherosclerosis at middle age predicts cerebral white matter lesions in the elderly. Stroke. 2000;31:425-429.
13. Whitmer RA, Gunderson EP, Barrett-Connor E, et al. Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study. BMJ. 2005;330:1360.
14. Leibson CK, Rocca WA, Hanson VA, et al. Risk of dementia among persons with diabetes mellitus: a population-based cohort study. Am J Epidemiol. 1997;145:301-308.
15. Peila R, Rodriguez B, Launer LJ. Type 2 diabetes, APOE gene and the risk for dementia and related pathologies. Diabetes. 2002;58:1629-1634.
16. Ott A, Stolk RP, van Harskamp F, et al. Diabetes mellitus and the risk of dementia: the Rotterdam Study. Neurology. 1999;53:1937-1942.
17. Braak H, de Vos RA, Jansen EN, et al. Neuropathological hallmarks of Alzheimer's and Parkinson's diseases. Prog Brain Res. 1998;117:267-285.
18. Kruit M, van Buchem MA, Hoffman PAM, et al. Migraine as a risk factor for subclinical brain lesions. JAMA. 2004;291:427-434.
19. Small SA, Tsai WY, DeLaPaz R, et al. Imaging hippocampal function across the human life span: is memory decline normal or not? Ann Neurol. 2002;53:290-295.
20. Sowell ER, Peterson BS, Thompson PM, et al. Mapping cortical change across the human life span. Nat Neurosci. 2003;6:309-315.
21. Petersen RC, Smith G, Kokmen E, et al. Memory function in normal aging. Neurology. 1992;42:396-401.
22. Salthouse TA. Aging and measures of processing speed. Biol Psychol. 2000;54:35-54.
23. Stewart R, Masaki K, Xue Q-L, et al. A 32-year prospective study of change in body weight and incident dementia. The Honolulu Asia-Aging Study. Arch Neurol. 2005;62:55-60.
24. Kyng KJ, May A, Steen K, et al. Gene expression profiling in Werner syndrome closely resembles that of normal aging. Proc Natl Acad Sci U S A. 2003;100:12259-12264.
25. Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med. 1999;340:115-126.
26. Festa A, D'Agostino R Jr, Tracy RP, et al. Insulin Resistance Atherosclerosis Study. Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: the insulin resistance atherosclerosis study. Diabetes. 2002;51:1131-1137.
27. McGeer PL, McGeer EG. Inflammatory pathogenesis in Alzheimer's disease: biological mechanisms and cognitive sequeli. Neurobiol Aging. 2001;22:799-809.
28. Cucchiara B, Kasner SE. Use of statins in CNS disorders. J Neurol Sci. 2001;187:81-89.
29. Stewart R, Liolitsa D. Type 2 diabetes mellitus, cognitive impairment and dementia. Diabetic Med. 1999;16:93-112.
30. Kalmijn S, Feskens EJM, Launer LJ, et al. Hyperinsulemia, impaired glucose tolerance and cognitive function (The Zutphen Elderly Study). Diabetologica. 1995;38:1096-1102.
31. Gregg EW, Yaffe K, Cauley JA, et al. Is diabetes associated with cognitive impairment and cognitive decline among older women? Arch Intern Med. 2000;160:174-180.
32. Haan MN, Shemanski L, Jagust WJ, et al. The role of APOE epsilon4 in modulating effects of other risk factors for cognitive decline in elderly men. JAMA. 1999;282:40-46.
33. Schmidt R, Launer LJ, Nilsson LG, et al. CASCADE Consortium. Magnetic resonance imaging of the brain in diabetes: the Cardiovascular Determinants of Dementia (CASCADE) Study. Diabetes. 2004;53:687-692.
34. Luchsinger JA, Tang MX, Stern Y, et al. Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort. Am J Epidemiol. 2001;154:635-641.
35. Diabetes Control and Complications Trial Research Group. Effects of intensive diabetes therapy on neuropsychological function in adults in the Diabetes Control and Complications Trial. Ann Intern Med. 1996;124:379-388.
36. Tuomilehto J, Lindstrom J, Eriksson JG, et al. Finnish Diabetes Prevention Study Group. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med. 2001;344:1343-1350.
37. Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346:393-403.
38. Kleinbaum D, Kupper L, Morgenstern H (eds). Epidemiologic Research. New York: Van Nostrand Reinhold Co; 1982:161.
39. Peila R, White LR, Masaki K, et al. Reducing the risk of dementia. Efficacy of long-term treatment of hypertension. Stroke. 2006;37:1165-1170.