Models of malignant glioma

Drug Discovery Today: Disease Models

Volumn 3, Issue 2, 2006, Pages 191-196

  Aldape, Ken ^a   Colman, Howard ^a   James, C David ^b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CD133 ANTIGEN; ONCOPROTEIN; PROTEIN P53; RAS PROTEIN; RETINOBLASTOMA PROTEIN; TELOMERASE; VIRUS PROTEIN;

ASTROCYTE; CANCER CELL CULTURE; CANCER INVASION; CANCER MODEL; CANCER MORTALITY; CARCINOGENESIS; CELL GROWTH; CELL IMMORTALIZATION; COMPUTER MODEL; DISEASE ACTIVITY; GENE ACTIVATION; GENETIC ENGINEERING; GLIOBLASTOMA; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INTERMETHOD COMPARISON; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PAPILLOMA VIRUS; PATHOPHYSIOLOGY; RAT; REVIEW; STEM CELL; TUMOR XENOGRAFT;

EID: 33747349033     PISSN: 17406757     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddmod.2006.06.002     Document Type: Review

References (38)

1. Becher O.J., and Holland E.C. Genetically engineered models have advantages over xenografts for preclinical studies. Cancer Res. 66 (2006) 3355-3358 (discussion 3358-3359)
2. Sausville E.A., and Burger A.M. Contributions of human tumor xenografts to anticancer drug development. Cancer Res. 66 (2006) 3351-3354 (discussion 3354)
3. Kennedy P.G., et al. Antigenic expression by cells derived from human gliomas does not correlate with morphological classification. Neuropathol. Appl. Neurobiol. 13 (1987) 327-347
4. Sonoda Y., et al. Akt pathway activation converts anaplastic astrocytoma to glioblastoma multiforme in a human astrocyte model of glioma. Cancer Res. 61 (2001) 6674-6678
5. Sonoda Y., et al. Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma. Cancer Res. 61 (2001) 4956-4960
6. Lund-Johansen M., et al. Multicellular tumor spheroids in serum-free culture. Anticancer Res. 9 (1989) 413-420
7. Lund-Johansen M., et al. Effect of epidermal growth factor on glioma cell growth, migration, and invasion in vitro. Cancer Res. 50 (1990) 6039-6044
8. Wang J.C., and Dick J.E. Cancer stem cells: lessons from leukemia. Trends Cell Biol. 15 (2005) 494-501
9. Zhang M., and Rosen J.M. Stem cells in the etiology and treatment of cancer. Curr. Opin. Genet. Dev. 16 (2006) 60-64
10. Galderisi U., et al. Stem cells and brain cancer. Cell Death Differ. 13 (2006) 5-11
11. Singh S.K., et al. Cancer stem cells in nervous system tumors. Oncogene 23 (2004) 7267-7273
12. Galli R., et al. Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res. 64 (2004) 7011-7021
13. Yuan X., et al. Isolation of cancer stem cells from adult glioblastoma multiforme. Oncogene 23 (2004) 9392-9400
14. Singh S.K., et al. Identification of human brain tumour initiating cells. Nature 432 (2004) 396-401
15. Giannini C., et al. Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme. Neuro-oncol. 7 (2005) 164-176
16. Sarkaria J.N., et al. Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response. Clin. Cancer Res. 12 7 Pt 1 (2006) 2264-2271
17. Yamini B., et al. Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma. Cancer Res. 64 (2004) 6381-6384
18. Schmidt N.O., et al. Antiangiogenic therapy by local intracerebral microinfusion improves treatment efficiency and survival in an orthotopic human glioblastoma model. Clin. Cancer Res. 10 (2004) 1255-1262
19. Zhang Y., et al. Intravenous RNA interference gene therapy targeting the human epidermal growth factor receptor prolongs survival in intracranial brain cancer. Clin. Cancer Res. 10 (2004) 3667-3677
20. Frederick L., et al. Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas. Cancer Res. 60 (2000) 1383-1387
21. Aldape K.D., et al. Immunohistochemical detection of EGFRvIII in high malignancy grade astrocytomas and evaluation of prognostic significance. J. Neuropathol. Exp. Neurol. 63 (2004) 700-707
22. Bigner S.H., et al. Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts. Cancer Res. 50 (1990) 8017-8022
23. Pandita A., et al. Contrasting in vivo and in vitro fates of glioblastoma cell subpopulations with amplified EGFR. Genes Chromosomes Cancer 39 (2004) 29-36
24. Antunes L., et al. Analysis of tissue chimerism in nude mouse brain and abdominal xenograft models of human glioblastoma multiforme: what does it tell us about the models and about glioblastoma biology and therapy?. J. Histochem. Cytochem. 48 (2000) 847-858
25. Leuraud P., et al. Correlation between genetic alterations and growth of human malignant glioma xenografted in nude mice. Br. J. Cancer 89 (2003) 2327-2332
26. Jeuken J.W., et al. Genetic reflection of glioblastoma biopsy material in xenografts: characterization of 11 glioblastoma xenograft lines by comparative genomic hybridization. J. Neurosurg. 92 (2000) 652-658
27. Horten B.C., et al. Xenograft of human malignant glial tumors into brains of nude mice. A histopatholgical study. J. Neuropathol. Exp. Neurol. 40 (1981) 493-511
28. Shapiro W.R., et al. Human brain tumor transplantation into nude mice. J. Natl. Cancer Inst. 62 (1979) 447-453
29. Mahesparan R., et al. Expression of extracellular matrix components in a highly infiltrative in vivo glioma model. Acta Neuropathol. (Berl.) 105 (2003) 49-57
30. Engebraaten O., et al. Growth of precultured human glioma specimens in nude rat brain. J. Neurosurg. 90 (1999) 125-132
31. Weiss W.A., et al. Genetic determinants of malignancy in a mouse model for oligodendroglioma. Cancer Res. 63 (2003) 1589-1595
32. Xiao A., et al. Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation. Cancer Cell 1 (2002) 157-168
33. Holland E.C., et al. Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nat. Genet. 25 (2000) 55-57
34. Ding H., et al. Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas. Cancer Res. 61 (2001) 3826-3836
35. Chiu I.M., et al. Tumorigenesis in transgenic mice in which the SV40 T antigen is driven by the brain-specific FGF1 promoter. Oncogene 19 (2000) 6229-6239
36. Weissenberger J., et al. Development and malignant progression of astrocytomas in GFAP-v-src transgenic mice. Oncogene 14 (1997) 2005-2013
37. Freije W.A., et al. Gene expression profiling of gliomas strongly predicts survival. Cancer Res. 64 (2004) 6503-6510
38. Phillips H.S., et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 9 (2006) 157-173