-
1
-
-
0041833334
-
ABC-transporters: Implications on drug resistance from microorganisms to human cancers
-
Lage H: ABC-transporters: implications on drug resistance from microorganisms to human cancers. Int J Antimicrob Agents 2003, 22:188-199.
-
(2003)
Int J Antimicrob Agents
, vol.22
, pp. 188-199
-
-
Lage, H.1
-
2
-
-
0642374221
-
The role of glutathione-S-transferase in anti-cancer drug resistance
-
Townsend DM, Tew KD: The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene 2003, 22:7369-7375.
-
(2003)
Oncogene
, vol.22
, pp. 7369-7375
-
-
Townsend, D.M.1
Tew, K.D.2
-
3
-
-
33644832665
-
Defects of the apoptotic pathway as therapeutic target against cancer
-
Mashima T, Tsuruo T: Defects of the apoptotic pathway as therapeutic target against cancer. Drug Resist Updat 2005, 8:339-343.
-
(2005)
Drug Resist Updat
, vol.8
, pp. 339-343
-
-
Mashima, T.1
Tsuruo, T.2
-
4
-
-
0036367871
-
Clinical development of P glycoprotein modulators in oncology
-
Oza AM: Clinical development of P glycoprotein modulators in oncology. Novartis Found Symp 2002, 243:103-115.
-
(2002)
Novartis Found Symp
, vol.243
, pp. 103-115
-
-
Oza, A.M.1
-
5
-
-
27644577664
-
ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal
-
Choi CH: ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal. Cancer Cell Int 2005, 5:30.
-
(2005)
Cancer Cell Int
, vol.5
, pp. 30
-
-
Choi, C.H.1
-
6
-
-
0034066072
-
Disorders in cell circuitry during multistage carcinogenesis: The role of homeostasis
-
Weinstein IB: Disorders in cell circuitry during multistage carcinogenesis: the role of homeostasis. Carcinogenesis 2000, 21:857-864.
-
(2000)
Carcinogenesis
, vol.21
, pp. 857-864
-
-
Weinstein, I.B.1
-
7
-
-
33644846509
-
Epigenetic gene silencing in cancer - A mechanism for early oncogenic pathway addiction?
-
Baylin SB, Ohm JE: Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction? Nat Rev Cancer 2006, 6:107-116.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 107-116
-
-
Baylin, S.B.1
Ohm, J.E.2
-
8
-
-
13144300125
-
Classification between normal and tumor tissues based on the pairwise gene expression ratio
-
Yap Y, Zhang X, Ling MT, Wang X, Wong YC, Danchin A: Classification between normal and tumor tissues based on the pairwise gene expression ratio. BMC Cancer 2004, 4:72.
-
(2004)
BMC Cancer
, vol.4
, pp. 72
-
-
Yap, Y.1
Zhang, X.2
Ling, M.T.3
Wang, X.4
Wong, Y.C.5
Danchin, A.6
-
9
-
-
27844594381
-
Cross-platform analysis of cancer microarray data improves gene expression based classification of phenotypes
-
Warnat P, Eils R, Brors B: Cross-platform analysis of cancer microarray data improves gene expression based classification of phenotypes. BMC Bioinformatics 2005, 6:265.
-
(2005)
BMC Bioinformatics
, vol.6
, pp. 265
-
-
Warnat, P.1
Eils, R.2
Brors, B.3
-
10
-
-
33645463549
-
The use of microarray technologies in clinical oncology
-
Gabriele L, Moretti F, Pierotti MA, Marincola FM, Foà R, Belardelli FM: The use of microarray technologies in clinical oncology. J Transl Med 2006, 4:8.
-
(2006)
J Transl Med
, vol.4
, pp. 8
-
-
Gabriele, L.1
Moretti, F.2
Pierotti, M.A.3
Marincola, F.M.4
Foà, R.5
Belardelli, F.M.6
-
11
-
-
33745037941
-
Deciphering cellular states of innate tumor drug responses
-
Graudens E, Boulanger V, Mollard C, Mariage-Samson R, Barlet X, Gremy G, Couillault C, Lajemi M, Piatier-Tonneau D, Zaborski P, Eveno E, Auffray C, Imbeaud S: Deciphering cellular states of innate tumor drug responses. Genome Biol 2006, 7:R19.
-
(2006)
Genome Biol
, vol.7
-
-
Graudens, E.1
Boulanger, V.2
Mollard, C.3
Mariage-Samson, R.4
Barlet, X.5
Gremy, G.6
Couillault, C.7
Lajemi, M.8
Piatier-Tonneau, D.9
Zaborski, P.10
Eveno, E.11
Auffray, C.12
Imbeaud, S.13
-
12
-
-
26844481904
-
Cancer cell adaptation to chemotherapy
-
Di Nicolantonio F, Mercer SJ, Knight LA, Gabriel FG, Whitehouse PA, Sharma S, Fernando A, Glaysher S, Di Palma S, Johnson P, Somers SS, Toh S, Higgins B, Lamont A, Gulliford T, Hurren J, Yiangou C, Cree IA: Cancer cell adaptation to chemotherapy. BMC Cancer 2005, 5:78.
-
(2005)
BMC Cancer
, vol.5
, pp. 78
-
-
Di Nicolantonio, F.1
Mercer, S.J.2
Knight, L.A.3
Gabriel, F.G.4
Whitehouse, P.A.5
Sharma, S.6
Fernando, A.7
Glaysher, S.8
Di Palma, S.9
Johnson, P.10
Somers, S.S.11
Toh, S.12
Higgins, B.13
Lamont, A.14
Gulliford, T.15
Hurren, J.16
Yiangou, C.17
Cree, I.A.18
-
13
-
-
33646128506
-
Epigenetics as a mechanism driving polygenic clinical drug resistance
-
Glasspool RM, Teodoridis JM, Brown R: Epigenetics as a mechanism driving polygenic clinical drug resistance. Br J Cancer 2006, 94:1087-1092.
-
(2006)
Br J Cancer
, vol.94
, pp. 1087-1092
-
-
Glasspool, R.M.1
Teodoridis, J.M.2
Brown, R.3
-
14
-
-
0142089873
-
The rise of DNA methylation and the importance of chromatin on multidrug resistance in cancer
-
Baker EK, El-Osta A: The rise of DNA methylation and the importance of chromatin on multidrug resistance in cancer. Exp Cell Res 2003, 290:177-194.
-
(2003)
Exp Cell Res
, vol.290
, pp. 177-194
-
-
Baker, E.K.1
El-Osta, A.2
-
15
-
-
0032948005
-
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
-
Cameron EE, Bachman KE, Myohanen S, Herman JG, Baylin SB: Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat Genet 1999, 21:103-107.
-
(1999)
Nat Genet
, vol.21
, pp. 103-107
-
-
Cameron, E.E.1
Bachman, K.E.2
Myohanen, S.3
Herman, J.G.4
Baylin, S.B.5
-
16
-
-
0037728813
-
Triple analysis of the cancer epigenome: An integrated microarray system for assessing gene expression, DNA methylation, and histone acetylation
-
Shi H, Wei SH, Leu YW, Rahmatpanah F, Liu JC, Yan PS, Nephew KP, Huang TH: Triple analysis of the cancer epigenome: an integrated microarray system for assessing gene expression, DNA methylation, and histone acetylation. Cancer Res 2003, 63:2164-2171.
-
(2003)
Cancer Res
, vol.63
, pp. 2164-2171
-
-
Shi, H.1
Wei, S.H.2
Leu, Y.W.3
Rahmatpanah, F.4
Liu, J.C.5
Yan, P.S.6
Nephew, K.P.7
Huang, T.H.8
-
17
-
-
17844382162
-
Epigenetic hypothesis tests for methylation and acetylation in a triple microarray system
-
Li L, Shi H, Yiannoutsos C, Huang TH, Nephew KP: Epigenetic hypothesis tests for methylation and acetylation in a triple microarray system. J Comput Biol 2005, 12:370-390.
-
(2005)
J Comput Biol
, vol.12
, pp. 370-390
-
-
Li, L.1
Shi, H.2
Yiannoutsos, C.3
Huang, T.H.4
Nephew, K.P.5
-
18
-
-
33645071947
-
Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines
-
Chavez-Blanco A, Perez-Plasencia C, Perez-Cardenas E, Carrasco-Legleu C, Rangel-Lopez E, Segura-Pacheco B, Taja-Chayeb L, Trejo-Becerril C, Gonzalez-Fierro A, Candelaria M, Cabrera G, Duenas-Gonzalez A: Antineoplastic effects of the DNA methylation inhibitor hydralazine and the histone deacetylase inhibitor valproic acid in cancer cell lines. Cancer Cell Int 2006, 6:2.
-
(2006)
Cancer Cell Int
, vol.6
, pp. 2
-
-
Chavez-Blanco, A.1
Perez-Plasencia, C.2
Perez-Cardenas, E.3
Carrasco-Legleu, C.4
Rangel-Lopez, E.5
Segura-Pacheco, B.6
Taja-Chayeb, L.7
Trejo-Becerril, C.8
Gonzalez-Fierro, A.9
Candelaria, M.10
Cabrera, G.11
Duenas-Gonzalez, A.12
-
19
-
-
33645088351
-
Overexpression of thymosin {beta}-4 renders SW480 colon carcinoma cells more resistant to apoptosis triggered by FasL and two topoisomerase II inhibitors via downregulating Fas and upregulating Survivin expression, respectively
-
Hsiao HL, Wang WS, Chen PM, Su Y: Overexpression of thymosin {beta}-4 renders SW480 colon carcinoma cells more resistant to apoptosis triggered by FasL and two topoisomerase II inhibitors via downregulating Fas and upregulating Survivin expression, respectively. Carcinogenesis 2006, 27:936-944.
-
(2006)
Carcinogenesis
, vol.27
, pp. 936-944
-
-
Hsiao, H.L.1
Wang, W.S.2
Chen, P.M.3
Su, Y.4
-
20
-
-
0036089883
-
Human colon cancer cells surviving high doses of cisplatin or oxaliplatin in vitro are not defective in DNA mismatch repair proteins
-
Sergent C, Franco N, Chapusot C, Lizard-Nacol S, Isambert N, Correia M, Chauffert B: Human colon cancer cells surviving high doses of cisplatin or oxaliplatin in vitro are not defective in DNA mismatch repair proteins. Cancer Chemother Pharmacol 2002, 49:445-452.
-
(2002)
Cancer Chemother Pharmacol
, vol.49
, pp. 445-452
-
-
Sergent, C.1
Franco, N.2
Chapusot, C.3
Lizard-Nacol, S.4
Isambert, N.5
Correia, M.6
Chauffert, B.7
-
21
-
-
0032694518
-
Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents
-
Liu L, Taverna P, Whitacre CM, Chatterjee S, Gerson SL: Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents. Clin Cancer Res 1999, 5:2908-2917.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2908-2917
-
-
Liu, L.1
Taverna, P.2
Whitacre, C.M.3
Chatterjee, S.4
Gerson, S.L.5
-
22
-
-
0036392059
-
DNA methylation and genomic imprinting: Insights from cancer into epigenetic mechanisms
-
Feinberg AP, Cui H, Ohlsson R: DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms. Semin Cancer Biol 2002, 12:389-398.
-
(2002)
Semin Cancer Biol
, vol.12
, pp. 389-398
-
-
Feinberg, A.P.1
Cui, H.2
Ohlsson, R.3
-
23
-
-
0037355911
-
Hypomethylation: One side of a larger picture
-
Dunn BK: Hypomethylation: one side of a larger picture. Ann N Y Acad Sci 2003, 983:28-42.
-
(2003)
Ann N Y Acad Sci
, vol.983
, pp. 28-42
-
-
Dunn, B.K.1
-
24
-
-
0036352687
-
Global and gene-specific methylation patterns in cancer: Aspects of tumor biology and clinical potential
-
Fruhwald MC, Plass C: Global and gene-specific methylation patterns in cancer: aspects of tumor biology and clinical potential. Mol Genet Metab 2002, 75:1-16.
-
(2002)
Mol Genet Metab
, vol.75
, pp. 1-16
-
-
Fruhwald, M.C.1
Plass, C.2
-
25
-
-
0036830336
-
Senescence and epigenetic dysregulation in cancer
-
Neumeister P, Albanese C, Balent B, Greally J, Pestell RG: Senescence and epigenetic dysregulation in cancer. Int J Biochem Cell Biol 2002, 34:1475-1490.
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 1475-1490
-
-
Neumeister, P.1
Albanese, C.2
Balent, B.3
Greally, J.4
Pestell, R.G.5
-
26
-
-
0037355935
-
Genetic and epigenetic mosaicism in cancer precursor tissues
-
Tycko B: Genetic and epigenetic mosaicism in cancer precursor tissues. Ann N Y Acad Sci 2003, 983:43-54.
-
(2003)
Ann N Y Acad Sci
, vol.983
, pp. 43-54
-
-
Tycko, B.1
-
27
-
-
21444445084
-
BABELOMICS: A suite of web tools for functional annotation and analysis of groups of genes in high-throughput experiments
-
Al-Shahrour F, Minguez P, Vaquerizas JM, Conde L, Dopazo J: BABELOMICS: a suite of web tools for functional annotation and analysis of groups of genes in high-throughput experiments. Nucleic Acids Res 2005, 33:W460-464.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Al-Shahrour, F.1
Minguez, P.2
Vaquerizas, J.M.3
Conde, L.4
Dopazo, J.5
-
28
-
-
84872267977
-
Babelomics, the systems biology way to functional annotation of genome-scale experiments
-
Babelomics, the systems biology way to functional annotation of genome-scale experiments [http://fatigo.bioinfo.cipf.es/]
-
-
-
-
29
-
-
7944230161
-
Epigenetic silencing mediated by CpG island methylation: Potential as a therapeutic target and as a biomarker
-
Teodoridis JM, Strathdee G, Brown R: Epigenetic silencing mediated by CpG island methylation: potential as a therapeutic target and as a biomarker. Drug Resist Updat 2004, 7:267-278.
-
(2004)
Drug Resist Updat
, vol.7
, pp. 267-278
-
-
Teodoridis, J.M.1
Strathdee, G.2
Brown, R.3
-
30
-
-
28544432478
-
Epigenetic changes to the MDRI locus in response to chemotherapeutic drugs
-
Baker EK, Johnstone RW, Zalcberg JR. El-Osta A: Epigenetic changes to the MDRI locus in response to chemotherapeutic drugs. Oncogene 2005, 24:8061-8075.
-
(2005)
Oncogene
, vol.24
, pp. 8061-8075
-
-
Baker, E.K.1
Johnstone, R.W.2
Zalcberg, J.R.3
El-Osta, A.4
-
31
-
-
27544434739
-
Epigenetic regulation of WTH3 in primary and cultured drug-resistant breast cancer cells
-
Tian K, Jurukovski V, Wang XP, Kaplan MH, Xu H: Epigenetic regulation of WTH3 in primary and cultured drug-resistant breast cancer cells. Cancer Res 2005, 65:10024-10031.
-
(2005)
Cancer Res
, vol.65
, pp. 10024-10031
-
-
Tian, K.1
Jurukovski, V.2
Wang, X.P.3
Kaplan, M.H.4
Xu, H.5
-
32
-
-
0030941622
-
Drug-induced DNA hypermethylation: A potential mediator of acquired drug resistance during cancer chemotherapy
-
Nyce JW: Drug-induced DNA hypermethylation: a potential mediator of acquired drug resistance during cancer chemotherapy. Mutat Res 1997, 386:153-161.
-
(1997)
Mutat Res
, vol.386
, pp. 153-161
-
-
Nyce, J.W.1
-
33
-
-
0027530945
-
Epigenetic mechanisms of drug resistance: Drug-induced DNA hypermethylation and drug resistance
-
Nyce J, Leonard S, Canupp D, Schulz S, Wong S: Epigenetic mechanisms of drug resistance: drug-induced DNA hypermethylation and drug resistance. Proc Natl Acad Sci USA 1993, 90:2960-2964.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 2960-2964
-
-
Nyce, J.1
Leonard, S.2
Canupp, D.3
Schulz, S.4
Wong, S.5
-
34
-
-
0024431109
-
Drug-induced DNA hypermethylation and drug resistance in human tumors
-
Nyce J: Drug-induced DNA hypermethylation and drug resistance in human tumors. Cancer Res 1989, 49:5829-5836.
-
(1989)
Cancer Res
, vol.49
, pp. 5829-5836
-
-
Nyce, J.1
-
35
-
-
0034326784
-
Reversal of drug resistance in human tumor xenografts by 2′-deoxy-5-azacytidine-induced demethylation of the hMLHI gene promoter
-
Plumb JA, Strathdee G, Sludden J, Kaye SB, Brown R: Reversal of drug resistance in human tumor xenografts by 2′-deoxy-5-azacytidine-induced demethylation of the hMLHI gene promoter. Cancer Res 2000, 60:6039-6044.
-
(2000)
Cancer Res
, vol.60
, pp. 6039-6044
-
-
Plumb, J.A.1
Strathdee, G.2
Sludden, J.3
Kaye, S.B.4
Brown, R.5
-
36
-
-
26044476923
-
Inhibition of DNA methyltransferase reverses cisplatin induced drug resistance in murine neuroblastoma cells
-
Qiu YY, Mirkin BL, Dwivedi RS: Inhibition of DNA methyltransferase reverses cisplatin induced drug resistance in murine neuroblastoma cells. Cancer Detect Prev 2005, 29:456-463.
-
(2005)
Cancer Detect Prev
, vol.29
, pp. 456-463
-
-
Qiu, Y.Y.1
Mirkin, B.L.2
Dwivedi, R.S.3
-
37
-
-
0242610850
-
Inhibition of histone deacetylase increases cytotoxicity to anti-cancer drugs targeting DNA
-
Kim MS, Blake M, Baek JH, Kohlhagen G, Pommier Y, Carrier F: Inhibition of histone deacetylase increases cytotoxicity to anti-cancer drugs targeting DNA. Cancer Res 2003, 63:7291-7300.
-
(2003)
Cancer Res
, vol.63
, pp. 7291-7300
-
-
Kim, M.S.1
Blake, M.2
Baek, J.H.3
Kohlhagen, G.4
Pommier, Y.5
Carrier, F.6
-
38
-
-
33645226815
-
Histone deacetylase inhibitors induce cell death and enhance the susceptibility to ionizing radiation, etoposide, and TRAIL in medulloblastoma cells
-
Sonnemann J, Kumar KS, Heesch S, Muller C, Hartwig C, Maass M, Bader P, Beck JF: Histone deacetylase inhibitors induce cell death and enhance the susceptibility to ionizing radiation, etoposide, and TRAIL in medulloblastoma. cells. Int J Oncol 2006, 28:755-766.
-
(2006)
Int J Oncol
, vol.28
, pp. 755-766
-
-
Sonnemann, J.1
Kumar, K.S.2
Heesch, S.3
Muller, C.4
Hartwig, C.5
Maass, M.6
Bader, P.7
Beck, J.F.8
-
39
-
-
33644856123
-
Epigenetic therapy of cancer: Past, present and future
-
Yoo CB, Jones PA: Epigenetic therapy of cancer: past, present and future. Nat Rev Drug Discov 2006, 5:37-50.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 37-50
-
-
Yoo, C.B.1
Jones, P.A.2
-
40
-
-
24744455483
-
Epigenome programming by Polycomb and Trithorax proteins
-
Cernilogar FM, Orlando V: Epigenome programming by Polycomb and Trithorax proteins. Biochem Cell Biol 2005, 83:322-331.
-
(2005)
Biochem Cell Biol
, vol.83
, pp. 322-331
-
-
Cernilogar, F.M.1
Orlando, V.2
|