-
2
-
-
0034589372
-
Neurotrophins and activity-dependent plasticity
-
Thoenen H. Neurotrophins and activity-dependent plasticity. Prog. Brain Res. 2000; 128: 183-191.
-
(2000)
Prog. Brain Res.
, vol.128
, pp. 183-191
-
-
Thoenen, H.1
-
3
-
-
0027972153
-
Neurotrophic factor therapy for nervous system degenerative diseases
-
Hefti F. Neurotrophic factor therapy for nervous system degenerative diseases. J. Neurobiol. 1994; 25: 1418-1435.
-
(1994)
J. Neurobiol.
, vol.25
, pp. 1418-1435
-
-
Hefti, F.1
-
4
-
-
0027067035
-
Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death
-
Yan Q, Elliott J, Snider WD. Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death. Nature 1992; 360: 753-755.
-
(1992)
Nature
, vol.360
, pp. 753-755
-
-
Yan, Q.1
Elliott, J.2
Snider, W.D.3
-
5
-
-
0027070473
-
Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section
-
Sendtner M, Holtmann B, Kolbeck R, Thoenen H, Barde YA. Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature 1992: 360: 757-759.
-
(1992)
Nature
, vol.360
, pp. 757-759
-
-
Sendtner, M.1
Holtmann, B.2
Kolbeck, R.3
Thoenen, H.4
Barde, Y.A.5
-
6
-
-
3943102116
-
Unraveling the mechanisms involved in motor neuron degeneration in ALS
-
Bruijn LI, Miller TM, Cleveland DW. Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu. Rev. Neurosci. 2004; 27: 723-749.
-
(2004)
Annu. Rev. Neurosci.
, vol.27
, pp. 723-749
-
-
Bruijn, L.I.1
Miller, T.M.2
Cleveland, D.W.3
-
7
-
-
0028040712
-
Brain-derived neurotrophic factor promotes differentiation of striatal GABAergic neurons
-
Mizuno K, Carnahan J, Nawa H. Brain-derived neurotrophic factor promotes differentiation of striatal GABAergic neurons. Dev. Biol. 1994; 165: 243-256.
-
(1994)
Dev. Biol.
, vol.165
, pp. 243-256
-
-
Mizuno, K.1
Carnahan, J.2
Nawa, H.3
-
8
-
-
0036312181
-
Recent advances in Huntington's disease: Implications for experimental therapeutics
-
Feigin A, Zgaljardic D. Recent advances in Huntington's disease: implications for experimental therapeutics. Curr. Opin. Neurol. 2002; 15: 483-489.
-
(2002)
Curr. Opin. Neurol.
, vol.15
, pp. 483-489
-
-
Feigin, A.1
Zgaljardic, D.2
-
9
-
-
0025168085
-
Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture
-
Alderson RF, Alterman AL, Barde YA, Lindsay RM. Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture. Neuron 1990; 5: 297-306.
-
(1990)
Neuron
, vol.5
, pp. 297-306
-
-
Alderson, R.F.1
Alterman, A.L.2
Barde, Y.A.3
Lindsay, R.M.4
-
10
-
-
0020072221
-
Alzheimer's disease and senile dementia: Loss of neurons in the basal forebrain
-
Whitehouse PJ, Price DL, Struble RG, Clark AW, Coyle JT, Delon MR. Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain. Science 1982; 215: 1237-1239.
-
(1982)
Science
, vol.215
, pp. 1237-1239
-
-
Whitehouse, P.J.1
Price, D.L.2
Struble, R.G.3
Clark, A.W.4
Coyle, J.T.5
Delon, M.R.6
-
11
-
-
0029610630
-
Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease
-
Levivier M, Przedborski S, Bencsics C, Kang UJ. Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease. J. Neurosci. 1995; 15: 7810-7820.
-
(1995)
J. Neurosci.
, vol.15
, pp. 7810-7820
-
-
Levivier, M.1
Przedborski, S.2
Bencsics, C.3
Kang, U.J.4
-
12
-
-
0025954066
-
Ageing and Parkinson's disease: Substantia nigra regional selectivity
-
Fearnley JM, Lees AJ. Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 1991; 114: 2283-2301.
-
(1991)
Brain
, vol.114
, pp. 2283-2301
-
-
Fearnley, J.M.1
Lees, A.J.2
-
13
-
-
0033034390
-
Molecular biology of neuroblastoma
-
Maris JM, Matthay KK. Molecular biology of neuroblastoma. J. Clin. Oncol. 1999; 17: 2264-2279.
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 2264-2279
-
-
Maris, J.M.1
Matthay, K.K.2
-
14
-
-
3343020830
-
Epidermal growth factor, neurotrophins and the metastatic cascade in prostate cancer
-
Montano X, Djamgoz MB. Epidermal growth factor, neurotrophins and the metastatic cascade in prostate cancer. FEBS Lett. 2004; 571: 1-8.
-
(2004)
FEBS Lett.
, vol.571
, pp. 1-8
-
-
Montano, X.1
Djamgoz, M.B.2
-
15
-
-
0041488911
-
Trk receptors: Roles in neuronal signal transduction
-
Huang EJ, Reichardt LF. Trk receptors: roles in neuronal signal transduction. Annu. Rev. Biochem. 2003; 72: 609-642.
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 609-642
-
-
Huang, E.J.1
Reichardt, L.F.2
-
16
-
-
0029556562
-
Structural and functional properties of the TRK family of neurotrophin receptors
-
Barbacid M. Structural and functional properties of the TRK family of neurotrophin receptors. Ann. N. Y. Acad. Sci. 1995; 766: 442-458.
-
(1995)
Ann. N. Y. Acad. Sci.
, vol.766
, pp. 442-458
-
-
Barbacid, M.1
-
17
-
-
0023942517
-
Growth factor receptor tyrosine kinases
-
Yarden Y, Ullrich A. Growth factor receptor tyrosine kinases. Annu. Rev. Biochem. 1988; 57: 443-478.
-
(1988)
Annu. Rev. Biochem.
, vol.57
, pp. 443-478
-
-
Yarden, Y.1
Ullrich, A.2
-
18
-
-
0027050178
-
Nerve growth factor mediates signal transduction through trk homodimer receptors
-
Jing S, Tapley P, Barbacid M. Nerve growth factor mediates signal transduction through trk homodimer receptors. Neuron 1992; 9: 1067-1079.
-
(1992)
Neuron
, vol.9
, pp. 1067-1079
-
-
Jing, S.1
Tapley, P.2
Barbacid, M.3
-
19
-
-
0025321521
-
Binding of brain-derived neurotrophic factor to the nerve growth factor receptor
-
Rodriguez-Tebar A, Dechant G, Barde YA. Binding of brain-derived neurotrophic factor to the nerve growth factor receptor. Neuron 1990; 4: 487-492.
-
(1990)
Neuron
, vol.4
, pp. 487-492
-
-
Rodriguez-Tebar, A.1
Dechant, G.2
Barde, Y.A.3
-
20
-
-
0030851905
-
NMR structure of the death domain of the p75 neurotrophin receptor
-
Liepinsh E, Ilag LL, Otting G, Ibanez CF. NMR structure of the death domain of the p75 neurotrophin receptor. EMBO J. 1997; 16: 4999-5005.
-
(1997)
EMBO J.
, vol.16
, pp. 4999-5005
-
-
Liepinsh, E.1
Ilag, L.L.2
Otting, G.3
Ibanez, C.F.4
-
21
-
-
0034730639
-
Chopper, a new death domain of the p75 neurotrophin receptor that mediates rapid neuronal cell death
-
Coulson EJ, Reid K, Baca M, Shipham KA, Hulett SM, Kilpatrick TJ, Bartlett PF. Chopper, a new death domain of the p75 neurotrophin receptor that mediates rapid neuronal cell death. J. Biol. Chem. 2000; 275: 30537-30545.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30537-30545
-
-
Coulson, E.J.1
Reid, K.2
Baca, M.3
Shipham, K.A.4
Hulett, S.M.5
Kilpatrick, T.J.6
Bartlett, P.F.7
-
22
-
-
0033081042
-
Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR
-
Bibel M, Hoppe E, Barde YA. Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR. EMBO J. 1999; 18: 616-622.
-
(1999)
EMBO J.
, vol.18
, pp. 616-622
-
-
Bibel, M.1
Hoppe, E.2
Barde, Y.A.3
-
23
-
-
0346849774
-
The p75 neurotrophin receptor: Multiple interactors and numerous functions
-
Gentry JJ, Barker PA, Carter BD. The p75 neurotrophin receptor: multiple interactors and numerous functions. Prog. Brain Res. 2004; 146: 25-39.
-
(2004)
Prog. Brain Res.
, vol.146
, pp. 25-39
-
-
Gentry, J.J.1
Barker, P.A.2
Carter, B.D.3
-
24
-
-
0025986121
-
New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor
-
McDonald NQ, Lapatto R, Murray-Rust J, Gunning J, Wlodawer A, Blundell TL. New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor. Nature 1991; 354: 411-414.
-
(1991)
Nature
, vol.354
, pp. 411-414
-
-
McDonald, N.Q.1
Lapatto, R.2
Murray-Rust, J.3
Gunning, J.4
Wlodawer, A.5
Blundell, T.L.6
-
25
-
-
0032387835
-
Crystal structure of neurotrophin-3 homodimer shows distinct regions are used to bind its receptors
-
Butte MJ, Hwang PK, Mobley WC, Fletterick RJ. Crystal structure of neurotrophin-3 homodimer shows distinct regions are used to bind its receptors. Biochemistry 1998; 37: 16846-16852.
-
(1998)
Biochemistry
, vol.37
, pp. 16846-16852
-
-
Butte, M.J.1
Hwang, P.K.2
Mobley, W.C.3
Fletterick, R.J.4
-
26
-
-
0033407459
-
The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site
-
Robinson RC, Radziejewski C, Spraggon G, Greenwald J, Kostura MR, Burtnick LD, Stuart DI, Choe S, Jones EY. The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/ neurotrophin 4 heterodimer reveal a common Trk-binding site. Protein Sci. 1999; 8: 2589-2597.
-
(1999)
Protein Sci.
, vol.8
, pp. 2589-2597
-
-
Robinson, R.C.1
Radziejewski, C.2
Spraggon, G.3
Greenwald, J.4
Kostura, M.R.5
Burtnick, L.D.6
Stuart, D.I.7
Choe, S.8
Jones, E.Y.9
-
27
-
-
0029064557
-
Neurotrophic factors: From structure-function studies to designing effective therapeutics
-
Ibanez CF. Neurotrophic factors: from structure-function studies to designing effective therapeutics. Trends Biotechnol. 1995; 13: 217-227.
-
(1995)
Trends Biotechnol.
, vol.13
, pp. 217-227
-
-
Ibanez, C.F.1
-
28
-
-
0033539065
-
Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor
-
Wiesmann C, Ultsch MH, Bass SH, de Vos AM. Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor. Nature 1999; 401: 184-188.
-
(1999)
Nature
, vol.401
, pp. 184-188
-
-
Wiesmann, C.1
Ultsch, M.H.2
Bass, S.H.3
de Vos, A.M.4
-
29
-
-
0031929229
-
Structure-activity relationships of conformationally constrained peptide analogues of loop 2 of brain-derived neurotrophic factor
-
O'Leary PD, Hughes RA. Structure-activity relationships of conformationally constrained peptide analogues of loop 2 of brain-derived neurotrophic factor. J. Neurochem. 1998; 70: 1712-1721.
-
(1998)
J. Neurochem.
, vol.70
, pp. 1712-1721
-
-
O'Leary, P.D.1
Hughes, R.A.2
-
30
-
-
0037477393
-
Design of potent peptide mimetics of brain-derived neurotrophic factor
-
O'Leary PD, Hughes RA. Design of potent peptide mimetics of brain-derived neurotrophic factor. J. Biol. Chem. 2003; 278: 25738-25744.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 25738-25744
-
-
O'Leary, P.D.1
Hughes, R.A.2
-
31
-
-
0344076149
-
A controlled trial of recombinant methionyl human BDNF in ALS
-
The BDNF Study Group (phase III)
-
The BDNF Study Group (phase III). A controlled trial of recombinant methionyl human BDNF in ALS. Neurology 1999; 52: 1427-1433.
-
(1999)
Neurology
, vol.52
, pp. 1427-1433
-
-
-
32
-
-
0036829006
-
Neurotrophins: From enthusiastic expectations through sobering experiences to rational therapeutic approaches
-
Thoenen H, Sendtner M. Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches. Nat. Neurosci. 2002; 5: 1046-1050.
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 1046-1050
-
-
Thoenen, H.1
Sendtner, M.2
-
33
-
-
6444226925
-
Randomized control trials in ALS: Lessons learned
-
Mitsumoto H, Gordon P, Kaufmann P, Gooch CL, Przedborski S, Rowland LP. Randomized control trials in ALS: lessons learned. Amyotroph. Lateral Scler. Other Motor Neuron Disord. 2004; 5: 8-13.
-
(2004)
Amyotroph. Lateral Scler. Other Motor Neuron Disord.
, vol.5
, pp. 8-13
-
-
Mitsumoto, H.1
Gordon, P.2
Kaufmann, P.3
Gooch, C.L.4
Przedborski, S.5
Rowland, L.P.6
-
34
-
-
0029928170
-
Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF
-
Poduslo JF, Curran GL. Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF. Brain Res. Mol. Brain Res. 1996; 36: 280-286.
-
(1996)
Brain Res. Mol. Brain Res.
, vol.36
, pp. 280-286
-
-
Poduslo, J.F.1
Curran, G.L.2
-
35
-
-
0028279458
-
Transport of human recombinant brain-derived neurotrophic factor (BDNF) through the rat blood-brain barrier in vivo using vector-mediated peptide drug delivery
-
Pardridge WM, Kang YS, Buciak JL. Transport of human recombinant brain-derived neurotrophic factor (BDNF) through the rat blood-brain barrier in vivo using vector-mediated peptide drug delivery. Pharm. Res. 1994; 11: 738-746.
-
(1994)
Pharm. Res.
, vol.11
, pp. 738-746
-
-
Pardridge, W.M.1
Kang, Y.S.2
Buciak, J.L.3
-
36
-
-
0025232814
-
Solid-phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids
-
Fields GB, Noble RL. Solid-phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids. Int. J. Pept. Protein Res. 1990; 35: 161-214.
-
(1990)
Int. J. Pept. Protein Res.
, vol.35
, pp. 161-214
-
-
Fields, G.B.1
Noble, R.L.2
-
37
-
-
12044255356
-
Disulfide bond formation in peptides by dimethyl sulfoxide. Scope and applications
-
Tam JP, Wu CR, Liu W, Zhang JW. Disulfide bond formation in peptides by dimethyl sulfoxide. Scope and applications. J. Am. Chem. Soc. 1991; 113: 6657-6662.
-
(1991)
J. Am. Chem. Soc.
, vol.113
, pp. 6657-6662
-
-
Tam, J.P.1
Wu, C.R.2
Liu, W.3
Zhang, J.W.4
-
38
-
-
84943706546
-
The synthesis of cystine peptides by iodine oxidation of S-tritylcysteine and S-acetamidomethylcysteine peptides
-
Kamber B, Hartmann A, Eisler K. et al. The synthesis of cystine peptides by iodine oxidation of S-tritylcysteine and S-acetamidomethylcysteine peptides. Helv. Chim. Acta 1980; 63: 899-915.
-
(1980)
Helv. Chim. Acta
, vol.63
, pp. 899-915
-
-
Kamber, B.1
Hartmann, A.2
Eisler, K.3
-
39
-
-
4444323608
-
A novel approach to the regioselective synthesis of a disulfide-linked heterodimeric bicyclic peptide mimetic of brain-derived neurotrophic factor
-
Fletcher JM, Hughes RA. A novel approach to the regioselective synthesis of a disulfide-linked heterodimeric bicyclic peptide mimetic of brain-derived neurotrophic factor. Tetrahedron Lett. 2004; 45: 6999-7001.
-
(2004)
Tetrahedron Lett.
, vol.45
, pp. 6999-7001
-
-
Fletcher, J.M.1
Hughes, R.A.2
-
40
-
-
0029151839
-
Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 bind to a single leucine-rich motif of TrkB
-
Windisch JM, Marksteiner R, Lang ME, Auer B, Schneider R. Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 bind to a single leucine-rich motif of TrkB. Biochemistry 1995; 34: 11256-11263.
-
(1995)
Biochemistry
, vol.34
, pp. 11256-11263
-
-
Windisch, J.M.1
Marksteiner, R.2
Lang, M.E.3
Auer, B.4
Schneider, R.5
|