The N-terminal domain of CCL21 reconstitutes high affinity binding, G protein activation, and chemotactic activity, to the C-terminal domain of CCL19

Biochemical and Biophysical Research Communications

Volumn 348, Issue 3, 2006, Pages 1089-1093

  Ott, Thomas R ^a   Lio, Francisco M ^a   Olshefski, Dennis ^a   Liu, Xin Jun ^a   Ling, Nicholas ^a   Struthers, R Scott ^a  

^a Neurocrine Biosciences ^*  (United States)

Author keywords

CCL19; CCL21; CCR7; Chemokine; Chemokine receptors

Indexed keywords

AMINO ACID; CHEMOKINE RECEPTOR CCR7; GUANINE NUCLEOTIDE BINDING PROTEIN; HEXAPEPTIDE; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; SECONDARY LYMPHOID TISSUE CHEMOKINE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CHEMOTAXIS; CHIMERA; CONTROLLED STUDY; DATA ANALYSIS; FEMALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RECEPTOR UPREGULATION; UPREGULATION;

AMINO ACID SEQUENCE; ANIMALS; CHEMOKINES, CC; CHEMOTAXIS; CHO CELLS; CRICETINAE; CRICETULUS; GTP-BINDING PROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

EID: 33747189527     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.07.165     Document Type: Article

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