Antihypertensive action of 2-hydroxyoleic acid in SHRs via modulation of the protein kinase A pathway and Rho kinase

Journal of Lipid Research

Volumn 47, Issue 8, 2006, Pages 1762-1770

  Alemany, Regina ^a   Vögler, Oliver ^a   Terés, Silvia ^a   Egea, Carolina ^a   Baamonde, Carmela ^a   Barceló, Francisca ^a   Delgado, Carlos ^b   Jakobs, Karl H ^c   Escribá, Pablo V ^a  

^a UNIVERSITAT DE LES ILLES BALEARS   (Spain)

^b Policlínica Miramar ^*  (Spain)

^c UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Aorta; cAMP dependent protein kinases; Fatty acids; Hypertension; Signal transduction; Spontaneously hypertensive rats

Indexed keywords

2 HYDROXYOLEIC ACID; 8 BROMO ADENOSINE 3',5' CYCLIC MONOPHOSPHOROTHIOIC ACID; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; OLEIC ACID; RHO KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIHYPERTENSIVE ACTIVITY; AORTA; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; HYPERTENSION; MUSCLE CONTRACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE;

ADENYLATE CYCLASE; ANIMALS; ANTIHYPERTENSIVE AGENTS; AORTA; BLOOD PRESSURE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; IMMUNOBLOTTING; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; OLEIC ACIDS; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SIGNAL TRANSDUCTION;

EID: 33747140793     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M500520-JLR200     Document Type: Article

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