Gz proteins are functionally coupled to dopamine D2-like receptors in vivo

Neuropharmacology

Volumn 51, Issue 3, 2006, Pages 597-605

  Leck, Kwong J ^a   Blaha, Charles D ^b   Matthaei, Klaus I ^a   Forster, Gina L ^b   Holgate, Joan ^a   Hendry, Ian A ^a  

^a Biology and Environment   (Australia)

^b MACQUARIE UNIVERSITY   (Australia)

Author keywords

Amperometry; G z knockout mouse; Psychostimulant; Quinpirole

Indexed keywords

2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; CORTICOTROPIN RELEASING FACTOR; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA Z SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; PROTEIN SUBUNIT; QUINPIROLE; SEROTONIN AGONIST; UNCLASSIFIED DRUG; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 7 HYDROXY 2 N,N DIPROPYLAMINOTETRALIN; 7-HYDROXY-2-N,N-DIPROPYLAMINOTETRALIN; CORTICOTROPIN; DOPAMINE; GNAZ PROTEIN, MOUSE; TETRALIN DERIVATIVE;

ALPHA CHAIN; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CORTICOTROPIN RELEASE; DOPAMINE BRAIN LEVEL; DOPAMINE RELEASE; DOPAMINERGIC ACTIVITY; DOPAMINERGIC NERVE CELL; DRUG INHIBITION; ELECTROSTIMULATION; FEMALE; FOREBRAIN; HYPOTHERMIA; LOCOMOTION; MALE; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR INTRINSIC ACTIVITY; SPECIES COMPARISON; WESTERN BLOTTING; WILD TYPE; ANIMAL; BLOOD; BODY TEMPERATURE; C57BL MOUSE; COMPARATIVE STUDY; DRUG EFFECT; METABOLISM; METHODOLOGY; MOTOR ACTIVITY; MOUSE MUTANT; PHYSIOLOGY; TIME;

2,3,4,5-TETRAHYDRO-7,8-DIHYDROXY-1-PHENYL-1H-3-BENZAZEPINE; 8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ADRENOCORTICOTROPIC HORMONE; ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; BODY TEMPERATURE; DOPAMINE; DOPAMINE AGONISTS; GTP-BINDING PROTEIN ALPHA SUBUNITS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; NUCLEUS ACCUMBENS; QUINPIROLE; RECEPTORS, DOPAMINE D2; SEROTONIN AGONISTS; TETRAHYDRONAPHTHALENES; TIME FACTORS;

EID: 33747071188     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2006.05.002     Document Type: Article

References (54)

1. Allgeier A., Laugwitz K.L., Van Sande J., Schultz G., and Dumont J.E. Multiple G-protein coupling of the dog thyrotropin receptor. Mol. Cell. Endocrinol. 127 (1997) 81-90
2. 3H]PD 128907, a putatively selective ligand for the D3 dopamine receptor, in rat brain: a receptor binding and quantitative autoradiographic study. Neuropsychopharmacology 18 (1998) 305-316
3. Benoit-Marand M., Borrelli E., and Gonon F. Inhibition of dopamine release via presynaptic D2 receptors: time course and functional characteristics in vivo. J. Neurosci. 21 (2001) 9134-9141
4. Borowsky B., and Kuhn C.M. D1 and D2 dopamine receptors stimulate hypothalamo-pituitary-adrenal activity in rats. Neuropharmacology 31 (1992) 671-678
5. Boulay D., Depoortere R., Perrault G., Borrelli E., and Sanger D.J. Dopamine D2 receptor knock-out mice are insensitive to the hypolocomotor and hypothermic effects of dopamine D2/D3 receptor agonists. Neuropharmacology 38 (1999) 1389-1396
6. Boulay D., Depoortere R., Rostene W., Perrault G., and Sanger D.J. Dopamine D3 receptor agonists produce similar decreases in body temperature and locomotor activity in D3 knock-out and wild-type mice. Neuropharmacology 38 (1999) 555-565
7. van den Buuse M., Martin S., Brosda J., Leck K.J., Matthaei K.I., and Hendry I. Enhanced effect of dopaminergic stimulation on prepulse inhibition in mice deficient in the alpha subunit of Gz. Psychopharmacology 183 (2005) 358-367
8. Chaperon F., Tricklebank M.D., Unger L., and Neijt H.C. Evidence for regulation of body temperature in rats by dopamine D2 receptor and possible influence of D1 but not D3 and D4 receptors. Neuropharmacology 44 (2003) 1047-1053
9. Crouch M.F., and Hendry I.A. Gi alpha and Gi beta are part of a signaling complex in Balb/c 3T3 cells: phosphorylation of Gi beta in growth factor activated fibroblasts. Cell Signal 5 (1993) 41-52
10. Crouch M.F., Heydon K., Garnaut S.M., Milburn P.J., and Hendry I.A. Retrograde axonal transport of the alpha subunit of the GTP binding protein Gz in mouse sciatic nerve: a potential pathway for signal transduction in neurons. Eur. J. Neurosci. 6 (1994) 626-631
11. Degtiar V.E., Harhammer R., and Nurnberg B. Receptors couple to L-type calcium channels via distinct Go proteins in rat neuroendocrine cell lines. J. Physiol. 502 (1997) 321-333
12. Dommett E., Coizet V., Blaha C.D., Martindale J., Lefebvre V., Walton N., Mayhew J.E., Overton P.G., and Redgrave P. How visual stimuli activate dopaminergic neurons at short latency. Science 307 (2005) 1476-1479
13. Forster G.L., and Blaha C.D. Pedunculopontine tegmental stimulation evokes striatal dopamine efflux by activation of acetylcholine and glutamate receptors in the midbrain and pons of the rat. Eur. J. Neurosci. 17 (2003) 751-762
14. Franco R., Ferre S., Agnati L., Torvinen M., Gines S., Hillion J., Casado V., Lledo P., Zoli M., Lluis C., and Fuxe K. Evidence for adenosine/dopamine receptor interactions: indications for heteromerization. Neuropsychopharmacology 23 (2000) S50-S59
15. Franklin K.B.J., and Paxinos G. The Mouse Brain in Stereotaxic Coordinates (1997), Academic Press, San Diego
16. zalpha. J. Biol. Chem. 273 (1998) 26008-26013
17. Grammatopoulos D.K., Randeva H.S., Levine M.A., Kanellopoulou K.A., and Hillhouse E.W. Rat cerebral cortex corticotropin-releasing hormone receptors: evidence for receptor coupling to multiple G-proteins. J. Neurochem. 76 (2001) 509-519
18. Hendry I.A., Kelleher K.L., Bartlett S.E., Leck K.J., Reynolds A.J., Heydon K., Mellick A., Megirian D., and Matthaei K.I. Hypertolerance to morphine in G(z alpha)-deficient mice. Brain Res. 870 (2000) 10-19
19. z-alpha, in neurons of brain and retina. J. Neurosci. 10 (1990) 2763-2770
20. z protein. Biol. Signals Recept. 7 (1998) 80-89
21. Hur E.M., and Kim K.T. G protein-coupled receptor signalling and cross-talk. Achieving rapidity and specificity. Cell. Signal. 14 (2002) 397-405
22. Jiang M., Spicher K., Boulay G., Wang Y., and Birnbaumer L. Most central nervous system D2 dopamine receptors are coupled to their effectors by Go. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 3577-3582
23. Joseph J.D., Wang Y.M., Miles P.R., Budygin E.A., Picetti R., Gainetdinov R.R., Caron M.G., and Wightman R.M. Dopamine autoreceptor regulation of release and uptake in mouse brain slices in the absence of D(3) receptors. Neuroscience 112 (2002) 39-49
24. Koeltzow T.E., Xu M., Cooper D.C., Hu X.T., Tonegawa S., Wolf M.E., and White F.J. Alterations in dopamine release but not dopamine autoreceptor function in dopamine D3 receptor mutant mice. J. Neurosci. 18 (1998) 2231-2238
25. L'hirondel M., Cheramy A., Godeheu G., Artaud F., Saiardi A., Borrelli E., and Glowinski J. Lack of autoreceptor-mediated inhibitory control of dopamine release in striatal synaptosomes of D2 receptor-deficient mice. Brain Res. 792 (1998) 253-262
26. Le Moine C., and Bloch B. Expression of the D3 dopamine receptor in peptidergic neurons of the nucleus accumbens: comparison with the D1 and D2 dopamine receptors. Neuroscience 73 (1996) 131-143
27. Levant B. Differential distribution of D3 dopamine receptors in the brains of several mammalian species. Brain Res. 800 (1998) 269-274
28. Levant B., Bancroft G.N., and Selkirk C.M. in vivo occupancy of D2 dopamine receptors by 7-OH-DPAT. Synapse 24 (1996) 60-64
29. 3H]quinpirole binding to human dopamine D2A and D3 receptors: effects of ions and guanine nucleotides. J. Pharmacol. Exp. Ther. 274 (1995) 790-797
30. Mende U., Zagrovic B., Cohen A., Li Y., Valenzuela D., Fishman M.C., and Neer E.J. Effect of deletion of the major brain G-protein alpha subunit (alpha(o)) on coordination of G-protein subunits and on adenylyl cyclase activity. J. Neurosci. Res. 54 (1998) 263-272
31. Missale C., Nash S.R., Robinson S.W., Jaber M., and Caron M.G. Dopamine receptors: from structure to function. Physiol. Rev. 78 (1998) 189-225
32. Monsma Jr. F.J., McVittie L.D., Gerfen C.R., Mahan L.C., and Sibley D.R. Multiple D2 dopamine receptors produced by alternative RNA splicing. Nature 342 (1989) 926-929
33. Morris B.J., Newman-Tancredi A., Audinot V., Simpson C.S., and Millan M.J. Activation of dopamine D(3) receptors induces c-fos expression in primary cultures of rat striatal neurons. J. Neurosci. Res. 59 (2000) 740-749
34. Muglia L.J., Jacobson L., Luedke C., Vogt S.K., Schaefer M.L., Dikkes P., Fukuda S., Sakai Y., Suda T., and Majzoub J.A. Corticotropin-releasing hormone links pituitary adrenocorticotropin gene expression and release during adrenal insufficiency. J. Clin. Invest. 105 (2000) 1269-1277
35. Oak J.N., Oldenhof J., and Van Tol H.H. The dopamine D(4) receptor: one decade of research. Eur. J. Pharmacol. 405 (2000) 303-327
36. s. Cell. Mol. Neurobiol. 19 (1999) 653-664
37. Ostrom R.S., Post S.R., and Insel P.A. Stoichiometry and compartmentation in G protein-coupled receptor signaling: implications for therapeutic interventions involving G(s). J. Pharmacol. Exp. Ther. 294 (2000) 407-412
38. Rivier C., and Vale W. Cocaine stimulates adrenocorticotropin (ACTH) secretion through a corticotropin-releasing factor (CRF)-mediated mechanism. Brain Res. 422 (1987) 403-406
39. Rouge-Pont F., Usiello A., Benoit-Marand M., Gonon F., Piazza P.V., and Borrelli E. Changes in extracellular dopamine induced by morphine and cocaine: crucial control by D2 receptors. J. Neurosci. 22 (2002) 3293-3301
40. Sautel F., Griffon N., Levesque D., Pilon C., Schwartz J.-C., and Sokoloff P. A functional test identifies dopamine agonists selective for D3 versus D2 receptors. Neuroreport 6 (1995) 329-332
41. 2+ currents in an insulin-secreting cell line (RINm5F). J. Biol. Chem. 266 (1991) 18025-18033
42. Schmitz Y., Lee C.J., Schmauss C., Gonon F., and Sulzer D. Amphetamine distorts stimulation-dependent dopamine overflow: effects on D2 autoreceptors, transporters, and synaptic vesicle stores. J. Neurosci. 21 (2001) 5916-5924
43. Serres F., Li Q., Garcia F., Raap D.K., Battaglia G., Muma N.A., and van de Kar L.D. Evidence that G(z)-proteins couple to hypothalamic 5-HT(1A) receptors in vivo. J. Neurosci. 20 (2000) 3095-3103
44. Sidhu A., and Niznik H.B. Coupling of dopamine receptor subtypes to multiple and diverse G proteins. Int. J. Dev. Neurosci. 18 (2000) 669-677
45. Starr B.S., and Starr M.S. Differential effects of dopamine D1 and D2 agonists and antagonists on velocity of movement, rearing and grooming in the mouse. Implications for the roles of D1 and D2 receptors. Neuropharmacology 25 (1986) 455-463
46. Sternweis P.C., and Robishaw J.D. Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain. J. Biol. Chem. 259 (1984) 13806-13813
47. Swanson C.J., Heath S., Stratford T.R., and Kelley A.E. Differential behavioral responses to dopaminergic stimulation of nucleus accumbens subregions in the rat. Pharmacol. Biochem. Behav. 58 (1997) 933-945
48. Tsunoda S., and Zuker C.S. The organization of INAD-signaling complexes by a multivalent PDZ domain protein in Drosophila photoreceptor cells ensures sensitivity and speed of signaling. Cell Calcium 26 (1999) 165-171
49. Uhl G.R., Hall F.S., and Sora I. Cocaine, reward, movement and monoamine transporters. Mol. Psychiatry 7 (2002) 21-26
50. Usiello A., Baik J.H., Rouge-Pont F., Picetti R., Dierich A., LeMeur M., Piazza P.V., and Borrelli E. Distinct functions of the two isoforms of dopamine D2 receptors. Nature 408 (2000) 199-203
51. z gtpase-activating protein subfamily. J. Biol. Chem. 273 (1998) 26014-26025
52. Wang Y., Xu R., Sasaoka T., Tonegawa S., Kung M.P., and Sankoorikal E.B. Dopamine D2 long receptor-deficient mice display alterations in striatum-dependent functions. J. Neurosci. 20 (2000) 8305-8314
53. z, results in abnormal platelet activation and altered responses to psychoactive drugs. Proc. Natl. Acad. Sci. U.S.A 97 (2000) 9984-9989
54. Zuch C.L., and Cory-Slechta D.A. Stimulus properties of 7-OH-DPAT versus auto- and postsynaptic receptor-specific doses of quinpirole. Pharmacol. Biochem. Behav. 68 (2001) 469-479