Total synthesis and biological evaluation of ustiloxin natural products and two analogs

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 18, 2006, Pages 4804-4807

  Li, Pixu ^a   Evans, Cory D ^a   Forbeck, Erin M ^a   Park, Haengsoon ^a   Bai, Ruoli ^b   Hamel, Ernest ^b   Joullie M M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Developmental Therapeutics Program   (United States)

Author keywords

Antimitotic agent; Biological evalution; Phomopsin; Total synthesis; Tubulin inhibitor; Ustiloxins D and F

Indexed keywords

6 ISOLEUCINE USTILOXIN; AZIRIDINE DERIVATIVE; ETHER DERIVATIVE; HYDROXYL GROUP; NATURAL PRODUCT; O METHOXYUSTILOXIN D; PHENOL DERIVATIVE; TUBULIN; UNCLASSIFIED DRUG; USTILOXIN; USTILOXIN D; USTILOXIN F;

ARTICLE; BIOLOGICAL ACTIVITY; DRUG ACTIVITY; DRUG BINDING; DRUG PROTEIN BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; RING OPENING;

BIOLOGICAL PRODUCTS; CELL LINE, TUMOR; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; MYCOTOXINS; PEPTIDES, CYCLIC; TUBULIN;

EID: 33746983512     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.06.071     Document Type: Article

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