메뉴 건너뛰기




Volumn 387, Issue 8, 2006, Pages 1017-1021

Regulation of human cathepsin B by alternative mRNA splicing: Homeostasis, fatal errors and cell death

Author keywords

Cysteine peptidases; Mitochondria; Overexpression; Trafficking; Unfolded protein; Untranslated region

Indexed keywords

CATHEPSIN B; CYSTEINE PEPTIDASE; MESSENGER RNA; PEPTIDASE; PROCATHEPSIN B; UNCLASSIFIED DRUG;

EID: 33746886312     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2006.125     Document Type: Short Survey
Times cited : (33)

References (31)
  • 1
    • 0028907722 scopus 로고
    • Cathepsin B in osteoarthritis: Zonal variation of enzyme activity in human femoral head cartilage
    • Baici, A., Hörler, D., Lang, A., Merlin, C., and Kissling, R. (1995a). Cathepsin B in osteoarthritis: zonal variation of enzyme activity in human femoral head cartilage. Ann. Rheum. Dis. 54, 281-288.
    • (1995) Ann. Rheum. Dis. , vol.54 , pp. 281-288
    • Baici, A.1    Hörler, D.2    Lang, A.3    Merlin, C.4    Kissling, R.5
  • 2
    • 0028901908 scopus 로고
    • Cathepsin B in osteoarthritis: Cytochemical and histochemical analysis of human femoral head cartilage
    • Baici, A., Lang, A., Hörler, D., Kissling, R., and Merlin, C. (1995b). Cathepsin B in osteoarthritis: cytochemical and histochemical analysis of human femoral head cartilage. Ann. Rheum. Dis. 54, 289-297.
    • (1995) Ann. Rheum. Dis. , vol.54 , pp. 289-297
    • Baici, A.1    Lang, A.2    Hörler, D.3    Kissling, R.4    Merlin, C.5
  • 3
    • 0034890869 scopus 로고    scopus 로고
    • Alternative messenger RNA splicing and enzyme forms of cathepsin B in human osteoarthritic cartilage and cultured chondrocytes
    • Berardi, S., Lang, A., Kostoulas, G., Hörler, D., Vilei, E.M., and Baici, A. (2001). Alternative messenger RNA splicing and enzyme forms of cathepsin B in human osteoarthritic cartilage and cultured chondrocytes. Arthritis Rheum. 44, 1819-1831.
    • (2001) Arthritis Rheum. , vol.44 , pp. 1819-1831
    • Berardi, S.1    Lang, A.2    Kostoulas, G.3    Hörler, D.4    Vilei, E.M.5    Baici, A.6
  • 4
    • 0029048724 scopus 로고
    • Identification of two new exons and multiple transcription start points in the 5′-untranslated region of the human cathepsin-B-encoding gene
    • Berquin, I.M., Cao, L., Fong, D., and Sloane, B.F. (1995). Identification of two new exons and multiple transcription start points in the 5′-untranslated region of the human cathepsin-B-encoding gene. Gene 159, 143-149.
    • (1995) Gene , vol.159 , pp. 143-149
    • Berquin, I.M.1    Cao, L.2    Fong, D.3    Sloane, B.F.4
  • 5
    • 0031465285 scopus 로고    scopus 로고
    • Exon 2 of human cathepsin B derives from an Alu element
    • Berquin, I.M., Ahram, M., and Sloane, B.F. (1997). Exon 2 of human cathepsin B derives from an Alu element. FEBS Lett. 419, 121-123.
    • (1997) FEBS Lett. , vol.419 , pp. 121-123
    • Berquin, I.M.1    Ahram, M.2    Sloane, B.F.3
  • 6
    • 33746904931 scopus 로고    scopus 로고
    • Mitochondrial processing peptidase
    • A.J. Barrett, N.D. Rawlings, and J.F. Woessner Jr., eds. (London, UK: Elsevier)
    • Braun, H.-P. and Schmitz, U.K. (2004). Mitochondrial processing peptidase. In: Handbook of Proteolytic Enzymes, A.J. Barrett, N.D. Rawlings, and J.F. Woessner Jr., eds. (London, UK: Elsevier), pp. 882-886.
    • (2004) Handbook of Proteolytic Enzymes , pp. 882-886
    • Braun, H.-P.1    Schmitz, U.K.2
  • 7
    • 18244392443 scopus 로고    scopus 로고
    • Cell death independent of caspases: A review
    • Bröker, L.E., Kruyt, F.A.E., and Giaccone, G. (2005). Cell death independent of caspases: a review. Clin. Cancer Res. 11, 3155-3162.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 3155-3162
    • Bröker, L.E.1    Kruyt, F.A.E.2    Giaccone, G.3
  • 8
    • 0036631379 scopus 로고    scopus 로고
    • How mitochondria import hydrophilic and hydrophobic proteins
    • Chacinska, A., Pfanner, N., and Meisinger, C. (2002). How mitochondria import hydrophilic and hydrophobic proteins. Trends Cell Biol. 12, 299-303.
    • (2002) Trends Cell Biol. , vol.12 , pp. 299-303
    • Chacinska, A.1    Pfanner, N.2    Meisinger, C.3
  • 9
    • 0022504458 scopus 로고
    • Isolation of a cDNA clone for the human lysosomal proteinase cathepsin B
    • USA
    • Fong, D., Calhoun, D.H., Hsieh, W.T., Lee, B., and Wells, R.D. (1986). Isolation of a cDNA clone for the human lysosomal proteinase cathepsin B. Proc. Natl. Acad. Sci. USA 83, 2909-2913.
    • (1986) Proc. Natl. Acad. Sci. , vol.83 , pp. 2909-2913
    • Fong, D.1    Calhoun, D.H.2    Hsieh, W.T.3    Lee, B.4    Wells, R.D.5
  • 10
    • 0003126050 scopus 로고    scopus 로고
    • Molecular regulation, membrane association and secretion of tumor cathepsin B
    • Frosch, B.A., Berquin, I., Emmert-Buck, M.R., Moin, K., and Sloane, B.F. (1999). Molecular regulation, membrane association and secretion of tumor cathepsin B. APMIS 107, 28-37.
    • (1999) APMIS , vol.107 , pp. 28-37
    • Frosch, B.A.1    Berquin, I.2    Emmert-Buck, M.R.3    Moin, K.4    Sloane, B.F.5
  • 11
    • 0027319177 scopus 로고
    • Characterization of the cathepsin B gene and multiple mRNAs in human tissues: Evidence for alternative splicing of cathepsin B pre-mRNA
    • Gong, Q., Chan, S.J., Bajkowski, A.S., Steiner, D.F., and Frankfater, A. (1993). Characterization of the cathepsin B gene and multiple mRNAs in human tissues: evidence for alternative splicing of cathepsin B pre-mRNA. DNA Cell Biol. 12, 299-309.
    • (1993) DNA Cell Biol. , vol.12 , pp. 299-309
    • Gong, Q.1    Chan, S.J.2    Bajkowski, A.S.3    Steiner, D.F.4    Frankfater, A.5
  • 13
    • 0030923532 scopus 로고    scopus 로고
    • Alternative splicing of the 5′ region of cathepsin B pre-messenger RNA in rheumatoid synovial tissue
    • Lemaire, R., Flipo, R.-M., Migaud, H., Fontaine, C., Huet, G., Dacquembronne, E., and Lafyatis, R. (1997). Alternative splicing of the 5′ region of cathepsin B pre-messenger RNA in rheumatoid synovial tissue. Arthritis Rheum. 40, 1540-1543.
    • (1997) Arthritis Rheum. , vol.40 , pp. 1540-1543
    • Lemaire, R.1    Flipo, R.-M.2    Migaud, H.3    Fontaine, C.4    Huet, G.5    Dacquembronne, E.6    Lafyatis, R.7
  • 14
    • 0034044314 scopus 로고    scopus 로고
    • The PSIPRED protein structure prediction server
    • McGuffin, L.J., Bryson, K., and Jones, D.T. (2000). The PSIPRED protein structure prediction server. Bioinformatics 16, 404-405.
    • (2000) Bioinformatics , vol.16 , pp. 404-405
    • McGuffin, L.J.1    Bryson, K.2    Jones, D.T.3
  • 15
    • 0032557529 scopus 로고    scopus 로고
    • In vivo expression of an alternatively spliced human tumor message that encodes a truncated form of cathepsin B. Subcellular distribution of the truncated enzyme in COS cells
    • Mehtani, S., Gong, Q.M., Panella, J., Subbiah, S., Peffley, D.M., and Frankfater, A. (1998). In vivo expression of an alternatively spliced human tumor message that encodes a truncated form of cathepsin B. Subcellular distribution of the truncated enzyme in COS cells. J. Biol. Chem. 273, 13236-13244.
    • (1998) J. Biol. Chem. , vol.273 , pp. 13236-13244
    • Mehtani, S.1    Gong, Q.M.2    Panella, J.3    Subbiah, S.4    Peffley, D.M.5    Frankfater, A.6
  • 16
    • 0036337915 scopus 로고    scopus 로고
    • A genomic view of alternative splicing
    • Modrek, B. and Lee, C. (2002). A genomic view of alternative splicing. Nat. Genet. 30, 13-19.
    • (2002) Nat. Genet. , vol.30 , pp. 13-19
    • Modrek, B.1    Lee, C.2
  • 18
    • 33746893630 scopus 로고    scopus 로고
    • Cathepsin B
    • A.J. Barrett, N.D. Rawlings, and J.F. Woessner Jr., eds. (London, UK: Elsevier)
    • Mort, J.S. (2004). Cathepsin B. In: Handbook of Proteolytic Enzymes, A.J. Barrett, N.D. Rawlings, and J.F. Woessner Jr., eds. (London, UK: Elsevier), pp. 1079-1086.
    • (2004) Handbook of Proteolytic Enzymes , pp. 1079-1086
    • Mort, J.S.1
  • 19
    • 0037297287 scopus 로고    scopus 로고
    • The alternative use of exons 2 and 3 in cathepsin B mRNA controls enzyme trafficking and triggers nuclear fragmentation in human cells
    • Müntener, K., Zwicky, R., Csucs, G., and Baici, A. (2003). The alternative use of exons 2 and 3 in cathepsin B mRNA controls enzyme trafficking and triggers nuclear fragmentation in human cells. Histochem. Cell Biol. 119, 93-101.
    • (2003) Histochem. Cell Biol. , vol.119 , pp. 93-101
    • Müntener, K.1    Zwicky, R.2    Csucs, G.3    Baici, A.4
  • 20
    • 4644267867 scopus 로고    scopus 로고
    • Exon skipping of cathepsin B: Mitochondrial targeting of a lysosomal peptidase provokes cell death
    • Müntener, K., Zwicky, R., Csucs, G., Rohrer, J., and Baici, A. (2004). Exon skipping of cathepsin B: mitochondrial targeting of a lysosomal peptidase provokes cell death. J. Biol. Chem. 279, 41012-41017.
    • (2004) J. Biol. Chem. , vol.279 , pp. 41012-41017
    • Müntener, K.1    Zwicky, R.2    Csucs, G.3    Rohrer, J.4    Baici, A.5
  • 21
    • 15744362474 scopus 로고    scopus 로고
    • Folding competence of N-terminally truncated forms of human procathepsin B
    • Müntener, K., Willimann, A., Zwicky, R., Svoboda, B., Mach, L., and Baici, A. (2005). Folding competence of N-terminally truncated forms of human procathepsin B. J. Biol. Chem. 280, 11973-11980.
    • (2005) J. Biol. Chem. , vol.280 , pp. 11973-11980
    • Müntener, K.1    Willimann, A.2    Zwicky, R.3    Svoboda, B.4    Mach, L.5    Baici, A.6
  • 22
    • 0038407572 scopus 로고    scopus 로고
    • Apoptoticdetection methods - From morphology to gene
    • Otsuki, Y., Li, Z.L., and Shibata, M.A. (2003). Apoptoticdetection methods - from morphology to gene. Prog. Histochem. Cytochem. 38, 275-340.
    • (2003) Prog. Histochem. Cytochem. , vol.38 , pp. 275-340
    • Otsuki, Y.1    Li, Z.L.2    Shibata, M.A.3
  • 24
    • 0035146891 scopus 로고    scopus 로고
    • Mitochondrial filaments and clusters as intracellular power-transmitting cables
    • Skulachev, V.P. (2001). Mitochondrial filaments and clusters as intracellular power-transmitting cables. Trends Biochem. Sci. 26, 23-29.
    • (2001) Trends Biochem. Sci. , vol.26 , pp. 23-29
    • Skulachev, V.P.1
  • 25
    • 0034687754 scopus 로고    scopus 로고
    • An alternative, nonapoptotic form of programmed cell death
    • USA
    • Sperandio, S., de Belle, I., and Bredesen, D.E. (2000). An alternative, nonapoptotic form of programmed cell death. Proc. Natl. Acad. Sci. USA 97, 14376-14381.
    • (2000) Proc. Natl. Acad. Sci. , vol.97 , pp. 14376-14381
    • Sperandio, S.1    De Belle, I.2    Bredesen, D.E.3
  • 26
    • 0028231609 scopus 로고
    • Human cathepsin B-encoding cDNAs: Sequence variations in the 3′-untranslated region
    • Tam, S.W., Cote-Paulino, L.R., Peak, D.A., Sheahan, K., and Murnane, M.J. (1994). Human cathepsin B-encoding cDNAs: sequence variations in the 3′-untranslated region. Gene 139, 171-176.
    • (1994) Gene , vol.139 , pp. 171-176
    • Tam, S.W.1    Cote-Paulino, L.R.2    Peak, D.A.3    Sheahan, K.4    Murnane, M.J.5
  • 27
    • 0029976244 scopus 로고    scopus 로고
    • Crystal structures of human procathepsin B at 3.2 and 3.3 Å resolution reveal an interaction motif between a papain-like cysteine protease and its propeptide
    • Turk, D., Podobnik, M., Kuhelj, R., Dolinar, M., and Turk, V. (1996). Crystal structures of human procathepsin B at 3.2 and 3.3 Å resolution reveal an interaction motif between a papain-like cysteine protease and its propeptide. FEBS Lett. 384, 211-214.
    • (1996) FEBS Lett. , vol.384 , pp. 211-214
    • Turk, D.1    Podobnik, M.2    Kuhelj, R.3    Dolinar, M.4    Turk, V.5
  • 29
    • 0038486779 scopus 로고    scopus 로고
    • Molecular regulation of human cathepsin B: Implication in pathologies
    • Yan, S.Q. and Sloane, B.F. (2003). Molecular regulation of human cathepsin B: implication in pathologies. Biol. Chem. 384, 845-854.
    • (2003) Biol. Chem. , vol.384 , pp. 845-854
    • Yan, S.Q.1    Sloane, B.F.2
  • 30
    • 0036796264 scopus 로고    scopus 로고
    • Cathepsin B expression and down-regulation by gene silencing and antisense DNA in human chondrocytes
    • Zwicky, R., Müntener, K., Goldring, M.B., and Baici, A. (2002). Cathepsin B expression and down-regulation by gene silencing and antisense DNA in human chondrocytes. Biochem. J. 367, 209-217.
    • (2002) Biochem. J. , vol.367 , pp. 209-217
    • Zwicky, R.1    Müntener, K.2    Goldring, M.B.3    Baici, A.4
  • 31
    • 0042856240 scopus 로고    scopus 로고
    • Exploring the role of 5′-alternative splicing and of the 3′-untranslated region of cathepsin B mRNA
    • Zwicky, R., Müntener, K., Csucs, G., Goldring, M.B., and Baici, A. (2003). Exploring the role of 5′-alternative splicing and of the 3′-untranslated region of cathepsin B mRNA. Biol. Chem. 384, 1007-1018.
    • (2003) Biol. Chem. , vol.384 , pp. 1007-1018
    • Zwicky, R.1    Müntener, K.2    Csucs, G.3    Goldring, M.B.4    Baici, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.