Cytokine-dependent proliferation of human CD34+ progenitor cells in the absence of serum is suppressed by their progeny's production of serine proteinases

Stem Cells

Volumn 24, Issue 2, 2006, Pages 299-306

  Goselink, Henriette M ^a   Hiemstra, Pieter S ^a   Van Noort, Peter ^a   Barge, Renée M Y ^a   Willemze, Roel ^a   Falkenburg, J H Frederik ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Hematopoietic growth factor; Hematopoietic progenitor cells; Serine proteinase; Serum free culture

Indexed keywords

4 (2 AMINOETHYL)BENZENESULFONYL FLUORIDE; ALBUMIN; ALPHA 1 ANTITRYPSIN; APROTININ; CATHEPSIN G; CYTOKINE; HEMOPOIETIC GROWTH FACTOR; INSULIN; LEUKOCYTE ELASTASE; LEUPEPTIN; MYELOBLASTIN; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; TRANSFERRIN; CD34 ANTIGEN; HGF PROTEIN, HUMAN; SCATTER FACTOR;

ARTICLE; BONE MARROW CELL; CD34 SELECTION; CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; DOSE RESPONSE; ENZYME RELEASE; ENZYME SYNTHESIS; GENE TRANSFER; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MONONUCLEAR CELL; PROGENY; PROTEIN DEGRADATION; STEM CELL; ANIMAL; BIOSYNTHESIS; DRUG EFFECT; ENZYMOLOGY; METABOLISM; PHYSIOLOGY; SECRETION; TIME;

ANIMALS; ANTIGENS, CD34; BONE MARROW CELLS; CELL PROLIFERATION; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; HEMATOPOIETIC STEM CELLS; HEPATOCYTE GROWTH FACTOR; HUMANS; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; TIME FACTORS;

EID: 33746881771     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2005-0153     Document Type: Article

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