Blood monocytes mimic endothelial progenitor cells

Stem Cells

Volumn 24, Issue 2, 2006, Pages 357-367

  Rohde, Eva ^a   Malischnik, Christina ^a   Thaler, Daniela ^a   Maierhofer, Theresa ^a   Linkesch, Werner ^a   Lanzer, Gerhard ^a   Guelly, Christian ^a   Strunk, Dirk ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Circulating angiogenic cells; Circulating endothelial cells; Circulating endothelial progenitors; Endothelial cells; Endothelial progenitor cells; Monocytes

Indexed keywords

CD14 ANTIGEN; CD31 ANTIGEN; CD45 ANTIGEN; CELL MARKER; ENDOGLIN; LECTIN; LOW DENSITY LIPOPROTEIN; VASCULAR ENDOTHELIAL CADHERIN; BIOLOGICAL MARKER; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANGIOGENESIS; ANTIGEN EXPRESSION; ARTICLE; BLOOD; CELL FUNCTION; CONTROLLED STUDY; ENDOTHELIUM CELL; EXPERIMENTAL MODEL; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; MALE; MEASUREMENT; MOLECULAR MIMICRY; MONOCYTE; NORMAL HUMAN; PHENOTYPE; PROGENY; PROTEIN BINDING; PROTEIN TRANSPORT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL STRAIN HL 60; ERYTHROID PRECURSOR CELL; EVALUATION; METABOLISM; PHYSIOLOGY; POLYMERASE CHAIN REACTION; UPREGULATION;

BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELLS, CULTURED; CHOLESTEROL, LDL; ENDOTHELIAL CELLS; ERYTHROID PROGENITOR CELLS; FLOW CYTOMETRY; HL-60 CELLS; HUMANS; LECTINS; MALE; MICROSCOPY, FLUORESCENCE; MONOCYTES; NEOVASCULARIZATION, PHYSIOLOGIC; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEM CELLS; UP-REGULATION;

EID: 33746881458     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2005-0072     Document Type: Article

References (45)

1. Kinnaird T, Stabile E, Burnett MS et al. Bone marrow-derived cells for enhancing collateral development: Mechanisms, animal data, and initial clinical experiences. Circ Res 2004;95:354-363.
2. Rafii S, Lyden D. Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration. Nat Med 2003;9:702-712.
3. Urbich C, Dimmeler S. Endothelial progenitor cells: Characterization and role in vascular biology. Circ Res 2004;95:343-353.
4. Asahara T, Murohara T, Sullivan A et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997;275:964-967.
5. Asahara T, Masuda H, Takahashi T et al. Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res 1999;85:221-228.
6. Ziegler BL, Valtieri M, Porada GA et al. KDR receptor: A key marker defining hematopoietic stem cells. Science 1999;285:1553-1558.
7. Peichev M, Naiyer AJ, Pereira D et al. Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood 2000;95:952-958.
8. Pelosi E, Valtieri M, Coppola S et al. Identification of the hemangioblast in postnatal life. Blood 2002;100:3203-3208.
9. Salven P, Mustjoki S, Alitalo R et al. VEGFR-3 and CD133 identify a population of CD34(+) lymphatic/vascular endothelial precursor cells. Blood 2003;101:168-172.
10. Risau W. Mechanisms of angiogenesis. Nature 1997;386:671-674.
11. Kalka C, Masuda H, Takahashi T et al. Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. Proc Natl Acad Sci U S A 2000;97:3422-3427.
12. Aoki M, Yasutake M, Murohara T. Derivation of functional endothelial progenitor cells from human umbilical cord blood mononuclear cells isolated by a novel cell filtration device. STEM CELLS 2004;22:994-1002.
13. Llevadot J, Murasawa S, Kureishi Y et al. HMG-CoA reductase inhibitor mobilizes bone marrow-derived endothelial progenitor cells. J Clin Invest 2001;108:399-405.
14. Dimmeler S, Aicher A, Vasa M et al. HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway. J Clin Invest 2001;108:391-397.
15. Walter DH, Rittig K, Bahlmann FH et al. Statin therapy accelerates reendothelialization: A novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells. Circulation 2002;105:3017-3024.
16. Vasa M, Fichtlscherer S, Aicher A et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 2001;89:E1-E7.
17. Vasa M, Fichtlscherer S, Adler K et al. Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease. Circulation 2001;103:2885-2890.
18. Pujol BF, Lucibello FC, Gehling UM et al. Endothelial-like cells derived from human CD14 positive monocytes. Differentiation 2000;65:287-300.
19. Schmeisser A, Garlichs CD, Zhang H et al. Monocytes coexpress endothelial and macrophagocytic lineage markers and form cord-like structures in Matrigel® under angiogenic conditions. Cardiovasc Res 2001;49:671-680.
20. Nakul-Aquaronne D, Bayle J, Frelin C. Coexpression of endothelial markers and CD14 by cytokine mobilized CD34(+) cells under angiogenic stimulation. Cardiovasc Res 2003;57:816-823.
21. Rehman J, Li JL, Orschell CM et al. Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors. Circulation 2003;107:1164-1169.
22. Urbich C, Heeschen C, Aicher A et al. Relevance of monocytic features for neovascularization capacity of circulating endothelial progenitor cells. Circulation 2003;108:2511-2516.
23. Lehmann JM, Riethmuller G, Johnson JP. MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily. Proc Natl Acad Sci U S A 1989;86:9891-9895.
24. Hill JM, Zalos G, Halcox JP et al. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 2003;348:593-600.
25. Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001;29:e45.
26. Lin Y, Chang LM, Solovey A et al. Use of blood outgrowth endothelial cells for gene therapy for hemophilia A. Blood 2002;99:457-462.
27. Lin Y, Weisdorf D, Solovey A et al. Origins of circulating endothelial cells and endothelial outgrowth from blood. J Clin Invest 2000;105:71-77.
28. Pickl WF, Majdic O, Fischer GF et al. MUC18/MCAM (CD146), an activation antigen of human T lymphocytes. J Immunol 1997;158:2107-2115.
29. Ingram DA, Caplice NM, Yoder MC. Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells. Blood 2005;106:1525-1531.
30. Ingram DA, Mead LE, Tanaka H et al. Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood 2004;104:2752-2760.
31. Ingram DA, Mead LE, Moore DB et al. Vessel wall-derived endothelial cells rapidly proliferate because they contain a complete hierarchy of endothelial progenitor cells. Blood 2005;105:2783-2786.
32. Solovey A, Lin Y, Browne P et al. Circulating activated endothelial cells in sickle cell anemia. N Engl J Med 1997;337:1584-1590.
33. Shintani S, Murohara T, Ikeda H et al. Mobilization of endothelial progenitor cells in patients with acute myocardial infarction. Circulation 2001;103:2776-2779.
34. Assmus B, Schachinger V, Teupe C et al. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction: (TOPCARE-AMI). Circulation 2002;106:3009-3017.
35. Ziegelhoeffer T, Fernandez B, Kostin S et al. Bone marrow-derived cells do not incorporate into the adult growing vasculature. Circ Res 2004;94:230-238.
36. Rajantie L, Ilmonen M, Alminaite A et al. Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells. Blood 2004;104:2084-2086.
37. Heil M, Ziegelhoeffer T, Mees B et al. A different outlook on the role of bone marrow stem cells in vascular growth: Bone marrow delivers software not hardware. Circ Res 2004;94:573-574.
38. Tomita S, Li RK, Weisel RD et al. Autologous transplantation of bone marrow cells improves damaged heart function. Circulation 1999;100:II247-II256.
39. Kobayashi T, Hamano K, Li TS et al. Enhancement of angiogenesis by the implantation of self bone marrow cells in a rat ischemic heart model. J Surg Res 2000;89:189-195.
40. Kamihata H, Matsubara H, Nishiue T et al. Implantation of bone marrow mononuclear cells into ischemic myocardium enhances collateral perfusion and regional function via side supply of angioblasts, angiogenic ligands, and cytokines. Circulation 2001;104:1046-1052.
41. Kamihata H, Matsubara H, Nishiue T et al. Improvement of collateral perfusion and regional function by implantation of peripheral blood mononuclear cells into ischemic hibernating myocardium. Arterioscler Thromb Vasc Biol 2002;22:1804-1810.
42. Reyes M, Dudek A, Jahagirdar B et al. Origin of endothelial progenitors in human postnatal bone marrow. J Clin Invest 2002;109:337-346.
43. Schmeisser A, Strasser RH. Phenotypic overlap between hematopoietic cells with suggested angioblastic potential and vascular endothelial cells. J Hematother Stem Cell Res 2002;11:69-79.
44. Abedin M, Tintut Y, Demer LL. Mesenchymal stem cells and the artery wall. Circ Res 2004;95:671-676.
45. Bou-Gharios G, Ponticos M, Rajkumar V et al. Extra-cellular matrix in vascular networks. Cell Prolif 2004;37:207-220.