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Stoeckli M., Chaurand P., Hallahan D.E., and Caprioli R.M. Imaging mass spectrometry: a new technology for the analysis of protein expression in mammalian tissues. Nat Med 7 (2001) 493-496
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Profiling and imaging proteins in tissue sections by mass spectrometry
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Review article summarizing tissue section imaging by MALDI-MS.
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Chaurand P., Schwartz S.A., and Caprioli R.M. Profiling and imaging proteins in tissue sections by mass spectrometry. Anal Chem 76 (2004) 86A-93A. Review article summarizing tissue section imaging by MALDI-MS.
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Proteomics in diagnostic pathology: profiling and imaging proteins directly in tissue sections
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Review article summarizing the clinical potential of protein profiles and images.
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Chaurand P., Sanders M.E., Jensen R.A., and Caprioli R.M. Proteomics in diagnostic pathology: profiling and imaging proteins directly in tissue sections. Am J Pathol 165 (2004) 1057-1068. Review article summarizing the clinical potential of protein profiles and images.
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Direct mapping on muscle tissues of duchenne myopathy biomarkers using both MALDI and cluster-SIMS imaging mass spectrometry
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Brunelle A., Touboul D., Piednoel H., Voisin V., De La Porte S., Tallarek E., Hagenhoff B., Halgand F., and Laprevote O. Direct mapping on muscle tissues of duchenne myopathy biomarkers using both MALDI and cluster-SIMS imaging mass spectrometry. Mol Biol Cell 15 (2004) 103A-104A
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Changes in phospholipid composition within the dystrophic muscle by matrix-assisted laser desorption/ionization mass spectrometry and mass spectrometry imaging
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Touboul D., Piednoel H., Voisin V., De La Porte S., Brunelle A., Halgand F., and Laprevote O. Changes in phospholipid composition within the dystrophic muscle by matrix-assisted laser desorption/ionization mass spectrometry and mass spectrometry imaging. Eur J Mass Spectrom 10 (2004) 657-664
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3342996780
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Molecular profiling of experimental Parkinson's disease: direct analysis of peptides and proteins on brain tissue sections by MALDI mass spectrometry
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Pierson J., Norris J.L., Aerni H.R., Svenningsson P., Caprioli R.M., and Andren P.E. Molecular profiling of experimental Parkinson's disease: direct analysis of peptides and proteins on brain tissue sections by MALDI mass spectrometry. J Proteome Res 3 (2004) 289-295
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Detection of pharmaceutical compounds in tissue by matrix-assisted laser desorption/ionization and laser desorption/chemical ionization tandem mass spectrometry with a quadrupole ion trap
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Direct analysis of drug candidates in tissue by matrix-assisted laser desorption/ionization mass spectrometry
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Reyzer M.L., Hsieh Y., Ng K., Korfmacher W.A., and Caprioli R.M. Direct analysis of drug candidates in tissue by matrix-assisted laser desorption/ionization mass spectrometry. J Mass Spectrom 38 (2003) 1081-1092
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MALDI mass spectrometric imaging of biological tissue sections
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Rohner T.C., Staab D., and Stoeckli M. MALDI mass spectrometric imaging of biological tissue sections. Mech Ageing Dev 126 (2005) 177-185
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Wang H.Y.J., Jackson S.N., McEuen J., and Woods A.S. Localization and analyses of small drug molecules in rat brain tissue sections. Anal Chem 77 (2005) 6682-6686
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Early changes in protein expression detected by mass spectrometry predict tumor response to molecular therapeutics
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Key reference demonstrating the correlation between the presence of a drug in tumor tissue and its influence on the proteome monitored by imaging mass spectrometry.
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Reyzer M.L., Caldwell R.L., Dugger T.C., Forbes J.T., Ritter C.A., Guix M., Arteaga C.L., and Caprioli R.M. Early changes in protein expression detected by mass spectrometry predict tumor response to molecular therapeutics. Cancer Res 64 (2004) 9093-9100. Key reference demonstrating the correlation between the presence of a drug in tumor tissue and its influence on the proteome monitored by imaging mass spectrometry.
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Direct tissue analysis using matrix-assisted laser desorption/ionization mass spectrometry: practical aspects of sample preparation
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Methodology article detailing the steps necessary for the successful analysis of tissue specimens by MALDI-MS.
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Schwartz S.A., Reyzer M.L., and Caprioli R.M. Direct tissue analysis using matrix-assisted laser desorption/ionization mass spectrometry: practical aspects of sample preparation. J Mass Spectrom 38 (2003) 699-708. Methodology article detailing the steps necessary for the successful analysis of tissue specimens by MALDI-MS.
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Schwartz, S.A.1
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Spatial profiling invertebrate ganglia using MALDI MS
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Kruse R., and Sweedler J.V. Spatial profiling invertebrate ganglia using MALDI MS. J Am Soc Mass Spectrom 14 (2003) 752-759
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Direct analysis of neuropeptides by in situ MALDI-TOF mass spectrometry in the rat brain
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Fournier I., Day R., and Salzet M. Direct analysis of neuropeptides by in situ MALDI-TOF mass spectrometry in the rat brain. Neuroendocrinol Lett 24 (2003) 9-14
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Solid ionic matrixes for direct tissue analysis and MALDI imaging
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First use of ionic matrices for profiling and imaging peptides and proteins from tissue sections by MALDI-MS.
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Lemaire R., Tabet J.C., Ducoroy P., Hendra J.B., Salzet M., and Fournier I. Solid ionic matrixes for direct tissue analysis and MALDI imaging. Anal Chem 78 (2006) 809-819. First use of ionic matrices for profiling and imaging peptides and proteins from tissue sections by MALDI-MS.
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In situ MALDI-TOF MS regional analysis of neutral phospholipids in lens tissue
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Rujoi M., Estrada R., and Yappert M.C. In situ MALDI-TOF MS regional analysis of neutral phospholipids in lens tissue. Anal Chem 76 (2004) 1657-1663
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Direct profiling and imaging of peptides and proteins from mammalian cells and tissue sections by mass spectrometry
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Chaurand P., and Caprioli R.M. Direct profiling and imaging of peptides and proteins from mammalian cells and tissue sections by mass spectrometry. Electrophoresis 23 (2002) 3125-3135
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Chaurand, P.1
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25
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Integrating histology and imaging mass spectrometry
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First use of MALDI-compatible tissue staining procedures and conductive glass slides as section support for profiling and imaging mass spectrometry.
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Chaurand P., Schwartz S.A., Billheimer D., Xu B.J., Crecelius A., and Caprioli R.M. Integrating histology and imaging mass spectrometry. Anal Chem 76 (2004) 1145-1155. First use of MALDI-compatible tissue staining procedures and conductive glass slides as section support for profiling and imaging mass spectrometry.
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Chaurand, P.1
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26
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Three-dimensional visualization of protein expression in mouse brain structures using imaging mass spectrometry
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Crecelius A.C., Cornett D.S., Caprioli R.M., Williams B., Dawant B.M., and Bodenheimer B. Three-dimensional visualization of protein expression in mouse brain structures using imaging mass spectrometry. J Am Soc Mass Spectrom 16 (2005) 1093-1099
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27
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Proteomic patterns of tumour subsets in non-small-cell lung cancer
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First demonstration that protein profiles generated by MALDI-MS from lung cancer and control tissue sections can be correlated with patient diagnosis and outcome.
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Yanagisawa K., Shyr Y., Xu B.J., Massion P.P., Larsen P.H., White B.C., Roberts J.R., Edgerton M., Gonzalez A., Nadaf S., et al. Proteomic patterns of tumour subsets in non-small-cell lung cancer. Lancet 362 (2003) 433-439. First demonstration that protein profiles generated by MALDI-MS from lung cancer and control tissue sections can be correlated with patient diagnosis and outcome.
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Yanagisawa, K.1
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28
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1042290316
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Protein profiling in brain tumors using mass spectrometry: feasibility of a new technique for the analysis of protein expression
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Schwartz S.A., Weil R.J., Johnson M.D., Toms S.A., and Caprioli R.M. Protein profiling in brain tumors using mass spectrometry: feasibility of a new technique for the analysis of protein expression. Clin Cancer Res 10 (2004) 981-987
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Clin Cancer Res
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Schwartz, S.A.1
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Caprioli, R.M.5
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29
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24744457360
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Proteomic-based prognosis of brain tumor patients using direct-tissue matrix-assisted laser desorption ionization mass spectrometry
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Demonstration that protein profiles generated by MALDI-MS from brain gliomas and control tissue sections can be correlated with patient diagnosis and outcome.
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Schwartz S.A., Weil R.J., Thompson R.C., Shyr Y., Moore J.H., Toms S.A., Johnson M.D., and Caprioli R.M. Proteomic-based prognosis of brain tumor patients using direct-tissue matrix-assisted laser desorption ionization mass spectrometry. Cancer Res 65 (2005) 7674-7681. Demonstration that protein profiles generated by MALDI-MS from brain gliomas and control tissue sections can be correlated with patient diagnosis and outcome.
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Cancer Res
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Schwartz, S.A.1
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Toms, S.A.6
Johnson, M.D.7
Caprioli, R.M.8
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30
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0036802247
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Imaging mass spectrometry: a new tool to investigate the spatial organization of peptides and proteins in mammalian tissue sections
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Chaurand P., Schwartz S.A., and Caprioli R.M. Imaging mass spectrometry: a new tool to investigate the spatial organization of peptides and proteins in mammalian tissue sections. Curr Opin Chem Biol 6 (2002) 676-681
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Curr Opin Chem Biol
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Chaurand, P.1
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31
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32444438927
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Automated acoustic matrix deposition for MALDI sample preparation
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Key reference showing that arrays of small matrix droplets can be automatically printed on tissue sections for MALDI imaging mass spectrometry.
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Aerni H.R., Cornett D.S., and Caprioli R.M. Automated acoustic matrix deposition for MALDI sample preparation. Anal Chem 78 (2006) 827-834. Key reference showing that arrays of small matrix droplets can be automatically printed on tissue sections for MALDI imaging mass spectrometry.
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Anal Chem
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Aerni, H.R.1
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Automated mass spectrometry imaging with a matrix-assisted laser desorption ionization time-of-flight instrument
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Stoeckli M., Farmer T.B., and Caprioli R.M. Automated mass spectrometry imaging with a matrix-assisted laser desorption ionization time-of-flight instrument. J Am Soc Mass Spectrom 10 (1999) 67-71
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Scanning microprobe matrix-assisted laser desorption ionization (SMALDI) mass spectrometry: instrumentation for sub-micrometer resolved LDI and MALDI surface analysis
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Spengler B., and Hubert M. Scanning microprobe matrix-assisted laser desorption ionization (SMALDI) mass spectrometry: instrumentation for sub-micrometer resolved LDI and MALDI surface analysis. J Am Soc Mass Spectrom 13 (2002) 735-748
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0242608321
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Profiling and imaging proteins in the mouse epididymis by imaging mass spectrometry
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Chaurand P., Fouchecourt S., DaGue B.B., Xu B.J., Reyzer M.L., Orgebin-Crist M.C., and Caprioli R.M. Profiling and imaging proteins in the mouse epididymis by imaging mass spectrometry. Proteomics 3 (2003) 2221-2239
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Proteomics
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Chaurand, P.1
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Caprioli, R.M.7
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35
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4544286905
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High-spatial resolution mass spectrometric imaging of peptide and protein distributions on a surface
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Interesting instrumentation and methodology for imaging by MALDI-MS using a position-sensitive mass spectrometer.
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Luxembourg S.L., Mize T.H., McDonnell L.A., and Heeren R.M.A. High-spatial resolution mass spectrometric imaging of peptide and protein distributions on a surface. Anal Chem 76 (2004) 5339-5344. Interesting instrumentation and methodology for imaging by MALDI-MS using a position-sensitive mass spectrometer.
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Anal Chem
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Luxembourg, S.L.1
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36
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4143070801
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Assessing protein patterns in disease using imaging mass spectrometry
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Chaurand P., Schwartz S.A., and Caprioli R.M. Assessing protein patterns in disease using imaging mass spectrometry. J Proteome Res 3 (2004) 245-252
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J Proteome Res
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Chaurand, P.1
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37
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Deciphering protein molecular signatures in cancer tissues to aid in diagnosis, prognosis, and therapy
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Perspective on the future role of profiling and imaging mass spectrometry in the clinical setting.
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Caprioli R.M. Deciphering protein molecular signatures in cancer tissues to aid in diagnosis, prognosis, and therapy. Cancer Res 65 (2005) 10642-10645. Perspective on the future role of profiling and imaging mass spectrometry in the clinical setting.
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Caprioli, R.M.1
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