Genistein potentiates the relaxation induced by β1- and β2- adrenoceptor activation in rat aortic rings

Journal of Cardiovascular Pharmacology

Volumn 35, Issue 2, 2000, Pages 227-233

  Satake, Nobuhiro ^a   Imanishi, Masami ^a,b   Keto, Yoshihiro ^a,c   Yamada, Hiroyuki ^a,c   Ishikawa, Makoto ^a,c   Shibata, Shoji ^a  

^a UNIVERSITY OF HAWAII   (United States)

^b NARA MEDICAL UNIVERSITY   (Japan)

^c KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

1 , 2 Adrenoceptors; cAMP PDE; Cytochrome P 450; Genistein; Isoproterenol; Rat aortic rings; Relaxation

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; ALPHA NAPHTHOFLAVONE; ATENOLOL; BETA 1 ADRENERGIC RECEPTOR; BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; CYTOCHROME P450 INHIBITOR; DOCEBENONE; FORSKOLIN; GENISTEIN; INDOMETACIN; ISOPRENALINE; MEPACRINE; METYRAPONE; PHOSPHOLIPASE A2 INHIBITOR; PROSTAGLANDIN SYNTHASE INHIBITOR; THEOPHYLLINE;

ANIMAL TISSUE; AORTA; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; DRUG SCREENING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VASODILATATION;

ADRENERGIC BETA-AGONISTS; ANIMALS; AORTA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENZYME INHIBITORS; GENISTEIN; ISOFLAVONES; ISOPROTERENOL; MALE; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2;

EID: 0033957253     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200002000-00008     Document Type: Article

References (3)

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3. Di Salvo J, Semenchuk L, Kolquist K, Pfitzer G. Tyrosine kinase inhibitors suppress agonist-induced contraction in smooth muscle. Biochem Biophys Res Commun 1993;190:968-74.